Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case report

Detalhes bibliográficos
Autor(a) principal: Gonçalo, Rani Iani Costa
Data de Publicação: 2020
Outros Autores: Medeiros, Cristiane Kalinne Santos, Chaves Neto, Humberto Pereira, Santos, Janaina Lessa de Moraes dos, Germano, Adriano Rocha, Queiroz, Lélia Maria Guedes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/8461
Resumo: Background: Osteosarcoma is a malignant neoplasm that occurs most often in long bones, with the head and neck region being rarely affected, accounting for less than 1% of all cancers in this region. Objective: To report a rare case of a large-extension osteosarcoma with emphasis on its clinical and diagnostic aspects. Case presentation: A 43-year-old woman presenting an intraoral exophytic lesion with involvement of other maxillofacial structures, such as nostril, zygoma and orbit. Despite the initial clinical diagnosis of actinomycosis, an incisional biopsy confirmed the histopathological diagnosis of osteosarcoma, showing a wide morphological variety. Conclusion: This case highlights the importance of clinical and histopathological findings for the correct diagnosis of osteosarcoma. Moreover, it shows that, although surgical resection is the primary treatment for this neoplasia, depending on the extent of the tumor and its proximity to vital anatomical structures, the most appropriate conduct is not always feasible.
id UNIFEI_ae25c67250b5e93b933b4b8ce073b0c7
oai_identifier_str oai:ojs.pkp.sfu.ca:article/8461
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case reportOsteosarcoma de gran extensión con la participación de estructuras maxillofaciales múltiples: un informe de caso raroOsteossarcoma de grande extensão com envolvimento de múltiplas estruturas maxilofaciais: um relato de caso raroCavidade OralNeoplasias de Cabeça e PescoçoNeoplasia ósseaOsteossarcoma.Cavidad OralNeoplasias de Cabeza y CuelloNeoplasia ÓseaOsteosarcoma.Oral cavityHead and Neck NeoplasmsBone NeoplasmOsteosarcoma.Background: Osteosarcoma is a malignant neoplasm that occurs most often in long bones, with the head and neck region being rarely affected, accounting for less than 1% of all cancers in this region. Objective: To report a rare case of a large-extension osteosarcoma with emphasis on its clinical and diagnostic aspects. Case presentation: A 43-year-old woman presenting an intraoral exophytic lesion with involvement of other maxillofacial structures, such as nostril, zygoma and orbit. Despite the initial clinical diagnosis of actinomycosis, an incisional biopsy confirmed the histopathological diagnosis of osteosarcoma, showing a wide morphological variety. Conclusion: This case highlights the importance of clinical and histopathological findings for the correct diagnosis of osteosarcoma. Moreover, it shows that, although surgical resection is the primary treatment for this neoplasia, depending on the extent of the tumor and its proximity to vital anatomical structures, the most appropriate conduct is not always feasible.Introducción: El osteosarcoma es una neoplasia maligna que se presenta con mayor frecuencia en huesos largos, siendo raramente afectada la región de cabeza y cuello, lo que corresponde a menos del 1% de todos los cánceres de esa región. Objetivo: Reportar un caso raro de osteosarcoma a gran escala, con énfasis en sus aspectos clínicos y diagnósticos. Presentación del caso: mujer de 43 años que presenta una lesión intraoral exofítica con afectación de otras estructuras maxilofaciales, como fosa nasal, cigoma y órbita. A pesar del diagnóstico clínico inicial de actinomicosis, la biopsia incisional confirmó el diagnóstico histopatológico de osteosarcoma, presentando una amplia variedad morfológica. Conclusión: El caso clínico destaca la importancia de los hallazgos clínicos e histopatológicos para el correcto diagnóstico del osteosarcoma. Además, muestra que, si bien la resección quirúrgica es el tratamiento primario de esta neoplasia, dependiendo de la extensión del tumor y su proximidad a estructuras anatómicas vitales, el abordaje más adecuado no siempre es factible.Introdução: O osteossarcoma é uma neoplasia maligna que ocorre mais frequentemente em ossos longos, sendo a região da cabeça e pescoço raramente afetada, correspondendo a menos de 1% de todos os cânceres nessa região. Objetivo: Relatar um caso raro de osteossarcoma de grande extensão, com ênfase em seus aspectos clínicos e diagnósticos. Apresentação do caso: Mulher de 43 anos apresentando lesão exofítica intraoral com envolvimento de outras estruturas maxilofaciais, como narina, zigoma e órbita. Apesar do diagnóstico clínico inicial de actinomicose, a biópsia incisional confirmou o diagnóstico histopatológico de osteossarcoma, apresentando uma grande variedade morfológica. Conclusão: O caso clínico destaca a importância dos achados clínicos e histopatológicos para o diagnóstico correto do osteossarcoma. Além disso, mostra que, embora a ressecção cirúrgica seja o tratamento primário dessa neoplasia, dependendo da extensão do tumor e de sua proximidade com estruturas anatômicas vitais, a conduta mais adequada nem sempre é viável.Research, Society and Development2020-09-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/846110.33448/rsd-v9i10.8461Research, Society and Development; Vol. 9 No. 10; e1519108461Research, Society and Development; Vol. 9 Núm. 10; e1519108461Research, Society and Development; v. 9 n. 10; e15191084612525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/8461/7459Copyright (c) 2020 Rani Iani Costa Gonçalo; Cristiane Kalinne Santos Medeiros; Humberto Pereira Chaves Neto; Janaina Lessa de Moraes dos Santos; Adriano Rocha Germano; Lélia Maria Guedes Queirozhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGonçalo, Rani Iani CostaMedeiros, Cristiane Kalinne Santos Chaves Neto, Humberto PereiraSantos, Janaina Lessa de Moraes dosGermano, Adriano RochaQueiroz, Lélia Maria Guedes 2020-10-31T12:03:23Zoai:ojs.pkp.sfu.ca:article/8461Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:30:55.749061Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case report
Osteosarcoma de gran extensión con la participación de estructuras maxillofaciales múltiples: un informe de caso raro
Osteossarcoma de grande extensão com envolvimento de múltiplas estruturas maxilofaciais: um relato de caso raro
title Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case report
spellingShingle Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case report
Gonçalo, Rani Iani Costa
Cavidade Oral
Neoplasias de Cabeça e Pescoço
Neoplasia óssea
Osteossarcoma.
Cavidad Oral
Neoplasias de Cabeza y Cuello
Neoplasia Ósea
Osteosarcoma.
Oral cavity
Head and Neck Neoplasms
Bone Neoplasm
Osteosarcoma.
title_short Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case report
title_full Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case report
title_fullStr Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case report
title_full_unstemmed Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case report
title_sort Large-extension osteosarcoma with involvement of multiple maxillofacial structures: a rare case report
author Gonçalo, Rani Iani Costa
author_facet Gonçalo, Rani Iani Costa
Medeiros, Cristiane Kalinne Santos
Chaves Neto, Humberto Pereira
Santos, Janaina Lessa de Moraes dos
Germano, Adriano Rocha
Queiroz, Lélia Maria Guedes
author_role author
author2 Medeiros, Cristiane Kalinne Santos
Chaves Neto, Humberto Pereira
Santos, Janaina Lessa de Moraes dos
Germano, Adriano Rocha
Queiroz, Lélia Maria Guedes
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Gonçalo, Rani Iani Costa
Medeiros, Cristiane Kalinne Santos
Chaves Neto, Humberto Pereira
Santos, Janaina Lessa de Moraes dos
Germano, Adriano Rocha
Queiroz, Lélia Maria Guedes
dc.subject.por.fl_str_mv Cavidade Oral
Neoplasias de Cabeça e Pescoço
Neoplasia óssea
Osteossarcoma.
Cavidad Oral
Neoplasias de Cabeza y Cuello
Neoplasia Ósea
Osteosarcoma.
Oral cavity
Head and Neck Neoplasms
Bone Neoplasm
Osteosarcoma.
topic Cavidade Oral
Neoplasias de Cabeça e Pescoço
Neoplasia óssea
Osteossarcoma.
Cavidad Oral
Neoplasias de Cabeza y Cuello
Neoplasia Ósea
Osteosarcoma.
Oral cavity
Head and Neck Neoplasms
Bone Neoplasm
Osteosarcoma.
description Background: Osteosarcoma is a malignant neoplasm that occurs most often in long bones, with the head and neck region being rarely affected, accounting for less than 1% of all cancers in this region. Objective: To report a rare case of a large-extension osteosarcoma with emphasis on its clinical and diagnostic aspects. Case presentation: A 43-year-old woman presenting an intraoral exophytic lesion with involvement of other maxillofacial structures, such as nostril, zygoma and orbit. Despite the initial clinical diagnosis of actinomycosis, an incisional biopsy confirmed the histopathological diagnosis of osteosarcoma, showing a wide morphological variety. Conclusion: This case highlights the importance of clinical and histopathological findings for the correct diagnosis of osteosarcoma. Moreover, it shows that, although surgical resection is the primary treatment for this neoplasia, depending on the extent of the tumor and its proximity to vital anatomical structures, the most appropriate conduct is not always feasible.
publishDate 2020
dc.date.none.fl_str_mv 2020-09-21
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/8461
10.33448/rsd-v9i10.8461
url https://rsdjournal.org/index.php/rsd/article/view/8461
identifier_str_mv 10.33448/rsd-v9i10.8461
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/8461/7459
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 10; e1519108461
Research, Society and Development; Vol. 9 Núm. 10; e1519108461
Research, Society and Development; v. 9 n. 10; e1519108461
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052740644372480