Left gastric artery embolization as an alternative for appetite suppression and weight loss in obese patients: an integrative review

• Autor(a) principal: Carvalho, Mateus Nunes
• Data de Publicação: 2021
• Outros Autores: Moura Filho, Edvaldo Pereira de, Silva, Igor Matheus Oliveira, Fernandes Neto, Jose, Vasconcelos, Carlos Augusto Cavalcante de, Nery, Raissa Pinheiro, Nunes, Raissa Martins de Oliveira, Santos, Ramodnil de Moura, Souza, Luan Kelves Miranda de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/11629
• topic: Cirurgia Bariátrica; Embolização Terapêutica; Grelina; Obesidade; Perda de peso.; Bariatric surgery; Embolization, therapeutic; Grelin; Obesity; Weight loss.; Cirugía bariátrica; Embolización Terapéutica; Ghrelina; Obesidad; Pérdida de peso.

Obesity is characterized by the excessive accumulation of body fat at a level that compromises the health of individuals and is associated with the development of chronic diseases. The treatment of obesity consists of diet modification, institution of physical activity and pharmacotherapy followed or not by bariatric surgery. Although surgery has shown positive results in terms of weight loss and reversal of comorbidities, the high cost, invasiveness, risk of mortality and the restriction of the population capable of performing the procedure, encourage research for alternative therapies. Thus, there is embolization of branches of the left gastric artery, in order to promote the suppression of the hormone ghrelin, an endovascular procedure for the treatment of obesity. The purpose of this literature review is to analyze published pre-clinical, clinical and retrospective studies to assess safety, efficacy, side effects, ghrelin levels and the excess weight loss achieved after follow-up over a period. Scientific publications were searched in the PubMed, Medline, CINHAL, Scopus, Cochrane and SCIELO databases from February/1999 to November/2020 and 15 studies were included. We concluded that it is too early to compare the effectiveness of this technique with bariatric surgery, as current reports describe only the experience with a limited number of patients with relatively short follow-up periods. In addition, the variability between these studies is high. Concerns were raised in initial studies about the delay in gastric emptying that can occur after this procedure, needing to be carefully evaluated.