Diagnosis of HPV in men: a systematic review

Detalhes bibliográficos
Autor(a) principal: Silva, Andressa Kelly Ferreira e
Data de Publicação: 2021
Outros Autores: Nascimento, Maria Luísa Lima Barreto do, Gomes Júnior, Antonio Luiz, Barreto, Humberto Medeiros, Costa Neto, João Soares da, Cruz, Maysa Gabriela Costa, Aquino, Kairo Igor Freitas de, Reis, Renandro de Carvalho
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/20064
Resumo: Human papillomavirus infection is the cause of several diseases in men and women. More than 100 types of HPV are known and about 30 are related to anogenital infection, with the most prevalent sexually transmitted viral infection worldwide. Given the proposal, the work aims to conduct a systematic review on the diagnosis of HPV in men. The study is a systematic review with the research question 'How is HPV diagnosed in men?' To answer this question, the descriptors “HPV OR papillomavirus” AND “diagnostic” and “man OR men” were used, in the PubMed, ScienceDirect and SciELO databases. After extracting the articles from the three databases and applying the inclusion and exclusion criteria, a total of 26 articles was reached at the end. Within the review, the most used methods for screening male HPV were seen, such as: peniscopy, cytological and histological evaluation, serological tests, p16 immunohistochemistry and molecular tests that are of great importance in the conclusive diagnosis, being reported in 14 articles. The genotype most found in the articles was HPV 16, a high-risk type of HPV, being mentioned in 11 studies. In addition, ten diseases were associated with HPV infection such as: cancer or anal dysplasia, head and neck cancer, penile cancer, co-infections with more than one HPV genotype and with HIV virus. This study was limited due to the lack of methodological standardization of the papers used. Although the prevalence of HPV infection in men is high, there is no consensus on which tests should be used to establish a diagnosis. The different methodologies have different sensitivity and specificity values, thus, the diagnosis of male HPV infection tends to associate the available methods.
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spelling Diagnosis of HPV in men: a systematic reviewDiagnóstico del VPH en hombres: una revisión sistemáticaDiagnóstico do HPV em homens: uma revisão sistemáticaTestes molecularesDisplasia analdisplasia analMétodosmétodosCâncer peniano.câncer penianoMolecular testsAnal dysplasiaanal dysplasiamethodsMethodspenile cancerPenile cancer.Pruebas molecularesdisplasia analDisplasia analMétodosmétodosCáncer de pene.cáncer de peneHuman papillomavirus infection is the cause of several diseases in men and women. More than 100 types of HPV are known and about 30 are related to anogenital infection, with the most prevalent sexually transmitted viral infection worldwide. Given the proposal, the work aims to conduct a systematic review on the diagnosis of HPV in men. The study is a systematic review with the research question 'How is HPV diagnosed in men?' To answer this question, the descriptors “HPV OR papillomavirus” AND “diagnostic” and “man OR men” were used, in the PubMed, ScienceDirect and SciELO databases. After extracting the articles from the three databases and applying the inclusion and exclusion criteria, a total of 26 articles was reached at the end. Within the review, the most used methods for screening male HPV were seen, such as: peniscopy, cytological and histological evaluation, serological tests, p16 immunohistochemistry and molecular tests that are of great importance in the conclusive diagnosis, being reported in 14 articles. The genotype most found in the articles was HPV 16, a high-risk type of HPV, being mentioned in 11 studies. In addition, ten diseases were associated with HPV infection such as: cancer or anal dysplasia, head and neck cancer, penile cancer, co-infections with more than one HPV genotype and with HIV virus. This study was limited due to the lack of methodological standardization of the papers used. Although the prevalence of HPV infection in men is high, there is no consensus on which tests should be used to establish a diagnosis. The different methodologies have different sensitivity and specificity values, thus, the diagnosis of male HPV infection tends to associate the available methods.La infección por el virus del papiloma humano es la causa de varias enfermedades en hombres y mujeres. Se conocen más de 100 tipos de VPH y alrededor de 30 están relacionados con la infección anogenital, siendo la infección viral de transmisión sexual más prevalente en todo el mundo. Ante la propuesta, el trabajo tiene como objetivo realizar una revisión sistemática sobre el diagnóstico de VPH en hombres. El estudio es una revisión sistemática con la pregunta de investigación '¿Cómo se diagnostica el VPH en los hombres?' Para responder a esta pregunta, se utilizaron los descriptores “VPH OR papillomavirus” AND “diagnóstico” y “hombre O hombres”, en las bases de datos PubMed, ScienceDirect y SciELO. Tras extraer los artículos de las tres bases de datos y aplicar los criterios de inclusión y exclusión, se alcanzó al final un total de 26 artículos. Dentro de la revisión, se observaron los métodos más utilizados para el cribado del VPH masculino, tales como: peniscopia, evaluación citológica e histológica, pruebas serológicas, inmunohistoquímica p16 y pruebas moleculares que son de gran importancia en el diagnóstico concluyente, siendo reportadas en 14 artículos. El genotipo más encontrado en los artículos fue el VPH 16, un tipo de VPH de alto riesgo, mencionado en 11 estudios. Además, diez enfermedades se asociaron a la infección por VPH como: cáncer o displasia anal, cáncer de cabeza y cuello, cáncer de pene, coinfecciones con más de un genotipo de VPH y con el virus del VIH. El estudio fue limitado debido a la falta de estandarización metodológica de los artículos utilizados. Aunque la prevalencia de la infección por VPH en los hombres es alta, no existe consenso sobre qué pruebas deben usarse para establecer un diagnóstico. Las diferentes metodologías tienen diferentes valores de sensibilidad y especificidad, por lo que el diagnóstico de infección por VPH masculina tiende a asociar los métodos disponibles.A infecção pelo papilomavírus humano é a causa de diversas doenças em homens e mulheres. Mais de 100 tipos de HPV são conhecidos e cerca de 30 estão relacionados à infecção anogenital, sendo a infecção viral sexualmente transmissível mais prevalente em todo o mundo. Diante do proposto, o trabalho tem como objetivo realizar uma revisão sistemática sobre o diagnóstico do HPV em homens. O estudo trata-se de uma revisão sistemática com a questão de pesquisa ‘como é realizado o diagnóstico do HPV em homens?’ Para responder a essa pergunta, foram utilizados os descritores “HPV OR papillomavirus” AND “diagnostic” AND “man OR men”, nas bases de dados do PubMed, ScienceDirect e SciELO. Após a extração dos artigos das três bases de dados e aplicação dos critérios de inclusão e exclusão, se chegou ao final com um total de 26 artigos. Dentro da revisão, foram vistos os métodos mais utilizados para a triagem de HPV masculino, como: a peniscopia, avaliação citológica e histológica, ensaios sorológicos, imuno-histoquímica de p16 e os testes moleculares que possuem grande importância no diagnóstico conclusivo, sendo relatados em 14 artigos. O genótipo mais encontrado nos artigos foi o HPV 16, tipo de HPV de alto risco, sendo mencionado em 11 estudos.  Além disso, dez enfermidades foram associadas à infecção por HPV como: câncer ou displasia anal, câncer de cabeça e pescoço, câncer peniano, coinfecções com mais de um genótipo de HPV e com vírus de HIV. O estudo foi limitado por falta de padronização metodológica dos artigos utilizados. Embora a prevalência de infecção por HPV em homens seja alta não existe consenso de quais testes devem ser usados ​​para estabelecer um diagnóstico. As diversas metodologias possuem valores de sensibilidade e especificidade diferentes, dessa forma, o diagnóstico da infecção de HPV masculino tende a associar os métodos disponíveis.Research, Society and Development2021-09-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2006410.33448/rsd-v10i12.20064Research, Society and Development; Vol. 10 No. 12; e329101220064Research, Society and Development; Vol. 10 Núm. 12; e329101220064Research, Society and Development; v. 10 n. 12; e3291012200642525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/20064/18288Copyright (c) 2021 Andressa Kelly Ferreira e Silva; Maria Luísa Lima Barreto do Nascimento; Antonio Luiz Gomes Júnior; Humberto Medeiros Barreto; João Soares da Costa Neto; Maysa Gabriela Costa Cruz; Kairo Igor Freitas de Aquino; Renandro de Carvalho Reishttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Andressa Kelly Ferreira eNascimento, Maria Luísa Lima Barreto doGomes Júnior, Antonio Luiz Barreto, Humberto MedeirosCosta Neto, João Soares daCruz, Maysa Gabriela CostaAquino, Kairo Igor Freitas deReis, Renandro de Carvalho2021-11-14T20:26:51Zoai:ojs.pkp.sfu.ca:article/20064Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:39:48.989931Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Diagnosis of HPV in men: a systematic review
Diagnóstico del VPH en hombres: una revisión sistemática
Diagnóstico do HPV em homens: uma revisão sistemática
title Diagnosis of HPV in men: a systematic review
spellingShingle Diagnosis of HPV in men: a systematic review
Silva, Andressa Kelly Ferreira e
Testes moleculares
Displasia anal
displasia anal
Métodos
métodos
Câncer peniano.
câncer peniano
Molecular tests
Anal dysplasia
anal dysplasia
methods
Methods
penile cancer
Penile cancer.
Pruebas moleculares
displasia anal
Displasia anal
Métodos
métodos
Cáncer de pene.
cáncer de pene
title_short Diagnosis of HPV in men: a systematic review
title_full Diagnosis of HPV in men: a systematic review
title_fullStr Diagnosis of HPV in men: a systematic review
title_full_unstemmed Diagnosis of HPV in men: a systematic review
title_sort Diagnosis of HPV in men: a systematic review
author Silva, Andressa Kelly Ferreira e
author_facet Silva, Andressa Kelly Ferreira e
Nascimento, Maria Luísa Lima Barreto do
Gomes Júnior, Antonio Luiz
Barreto, Humberto Medeiros
Costa Neto, João Soares da
Cruz, Maysa Gabriela Costa
Aquino, Kairo Igor Freitas de
Reis, Renandro de Carvalho
author_role author
author2 Nascimento, Maria Luísa Lima Barreto do
Gomes Júnior, Antonio Luiz
Barreto, Humberto Medeiros
Costa Neto, João Soares da
Cruz, Maysa Gabriela Costa
Aquino, Kairo Igor Freitas de
Reis, Renandro de Carvalho
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Andressa Kelly Ferreira e
Nascimento, Maria Luísa Lima Barreto do
Gomes Júnior, Antonio Luiz
Barreto, Humberto Medeiros
Costa Neto, João Soares da
Cruz, Maysa Gabriela Costa
Aquino, Kairo Igor Freitas de
Reis, Renandro de Carvalho
dc.subject.por.fl_str_mv Testes moleculares
Displasia anal
displasia anal
Métodos
métodos
Câncer peniano.
câncer peniano
Molecular tests
Anal dysplasia
anal dysplasia
methods
Methods
penile cancer
Penile cancer.
Pruebas moleculares
displasia anal
Displasia anal
Métodos
métodos
Cáncer de pene.
cáncer de pene
topic Testes moleculares
Displasia anal
displasia anal
Métodos
métodos
Câncer peniano.
câncer peniano
Molecular tests
Anal dysplasia
anal dysplasia
methods
Methods
penile cancer
Penile cancer.
Pruebas moleculares
displasia anal
Displasia anal
Métodos
métodos
Cáncer de pene.
cáncer de pene
description Human papillomavirus infection is the cause of several diseases in men and women. More than 100 types of HPV are known and about 30 are related to anogenital infection, with the most prevalent sexually transmitted viral infection worldwide. Given the proposal, the work aims to conduct a systematic review on the diagnosis of HPV in men. The study is a systematic review with the research question 'How is HPV diagnosed in men?' To answer this question, the descriptors “HPV OR papillomavirus” AND “diagnostic” and “man OR men” were used, in the PubMed, ScienceDirect and SciELO databases. After extracting the articles from the three databases and applying the inclusion and exclusion criteria, a total of 26 articles was reached at the end. Within the review, the most used methods for screening male HPV were seen, such as: peniscopy, cytological and histological evaluation, serological tests, p16 immunohistochemistry and molecular tests that are of great importance in the conclusive diagnosis, being reported in 14 articles. The genotype most found in the articles was HPV 16, a high-risk type of HPV, being mentioned in 11 studies. In addition, ten diseases were associated with HPV infection such as: cancer or anal dysplasia, head and neck cancer, penile cancer, co-infections with more than one HPV genotype and with HIV virus. This study was limited due to the lack of methodological standardization of the papers used. Although the prevalence of HPV infection in men is high, there is no consensus on which tests should be used to establish a diagnosis. The different methodologies have different sensitivity and specificity values, thus, the diagnosis of male HPV infection tends to associate the available methods.
publishDate 2021
dc.date.none.fl_str_mv 2021-09-23
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/20064
10.33448/rsd-v10i12.20064
url https://rsdjournal.org/index.php/rsd/article/view/20064
identifier_str_mv 10.33448/rsd-v10i12.20064
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/20064/18288
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 12; e329101220064
Research, Society and Development; Vol. 10 Núm. 12; e329101220064
Research, Society and Development; v. 10 n. 12; e329101220064
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
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instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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