Strategies for rationalizing antimicrobials in a high-complexity oncology care center

Detalhes bibliográficos
Autor(a) principal: Oliveira, Annie Elisandra Mesquita de
Data de Publicação: 2022
Outros Autores: Santos , Valéria Regina Cavalcante dos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/27937
Resumo: Objective: Implement a reformulation of the therapeutic use antimicrobial form used by the HOL (Hospital Ophir Loyola), focusing on the rational use of restricted use antimicrobials in the Intensive Care Center (ICU). Methods: This is a quali-quantitative, cross-sectional and retrospective study, through data collection, using application forms for antimicrobials for restricted therapeutic use, from August to December 2018. Results: A total of 479 forms of request for antimicrobials for restricted therapeutic use in the ICU were evaluated. The main antimicrobials prescribed were: meropenem (n = 79; 16.5%), vancomycin (n = 60; 12.7%), piperacillin sodium + tazobactam sodium (n = 60; 12.5%), ceftriaxone (n = 50; 10.6%) and ciprofloxacin (n = 50; 10.6%) and the most consumed in DDD/1000 beds/day were: meropenem, fluconazole, vancomycin, ciprofloxacin, sodium piperacillin + sodium tazobactam and polymyxin B. The probable infectious diagnosis, justifying the antimicrobial request was sepsis (n = 124; 25.9%). Most patients were empirically indicated for medication (n = 396; 82.7%). The infectious agents, isolated in culture exams, more incidents were: acinetobacter baumanni and pseudomonas aeruginosa. In view of the results, the main changes were established in the components of the request form for antimicrobials for therapeutic use. Conclusion: This research proposed the restructuring of the form of antimicrobials for therapeutic use, in order to increase the control of the use of drugs of restricted use. Once in use, it will contribute to the optimization of the rational use of antimicrobials. The implementation of the adapted form, resulting as a product of this research, may be extended as a suggestion to professionals from hospital institutions who may be interested in initiating actions consistent with the antimicrobial use management program.
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spelling Strategies for rationalizing antimicrobials in a high-complexity oncology care centerEstrategias para la racionalización de antimicrobianos en un centro de atención oncológica de alta complejidadEstratégias para racionalização de antimicrobianos em um centro de assistência de alta complexidade em oncologiaAntimicrobianosResistência bacterianaGestão de antimicrobianos.AntimicrobianosResistencia bacterianaManejo de antimicrobianos.AntimicrobialsBacterial resistanceAntimicrobial management.Objective: Implement a reformulation of the therapeutic use antimicrobial form used by the HOL (Hospital Ophir Loyola), focusing on the rational use of restricted use antimicrobials in the Intensive Care Center (ICU). Methods: This is a quali-quantitative, cross-sectional and retrospective study, through data collection, using application forms for antimicrobials for restricted therapeutic use, from August to December 2018. Results: A total of 479 forms of request for antimicrobials for restricted therapeutic use in the ICU were evaluated. The main antimicrobials prescribed were: meropenem (n = 79; 16.5%), vancomycin (n = 60; 12.7%), piperacillin sodium + tazobactam sodium (n = 60; 12.5%), ceftriaxone (n = 50; 10.6%) and ciprofloxacin (n = 50; 10.6%) and the most consumed in DDD/1000 beds/day were: meropenem, fluconazole, vancomycin, ciprofloxacin, sodium piperacillin + sodium tazobactam and polymyxin B. The probable infectious diagnosis, justifying the antimicrobial request was sepsis (n = 124; 25.9%). Most patients were empirically indicated for medication (n = 396; 82.7%). The infectious agents, isolated in culture exams, more incidents were: acinetobacter baumanni and pseudomonas aeruginosa. In view of the results, the main changes were established in the components of the request form for antimicrobials for therapeutic use. Conclusion: This research proposed the restructuring of the form of antimicrobials for therapeutic use, in order to increase the control of the use of drugs of restricted use. Once in use, it will contribute to the optimization of the rational use of antimicrobials. The implementation of the adapted form, resulting as a product of this research, may be extended as a suggestion to professionals from hospital institutions who may be interested in initiating actions consistent with the antimicrobial use management program.Objetivo: Implementar una reformulación del formulario de antimicrobianos de uso terapéutico utilizado por el HOL (Hospital Ophir Loyola), con foco en el uso racional de antimicrobianos de uso restringido en la Unidad de Cuidados Intensivos (UCI). Métodos: Se trata de un estudio cuali-cuantitativo, transversal y retrospectivo, mediante recolección de datos, utilizando formularios de solicitud de antimicrobianos de uso terapéutico restringido, de agosto a diciembre de 2018. Resultados: Un total de 479 formularios de solicitud de antimicrobianos de uso terapéutico restringido. se evaluó el uso en la UCI. Los principales antimicrobianos prescritos fueron: meropenem (n = 79; 16,5%), vancomicina (n = 60; 12,7%), piperacilina sódica + tazobactam sódico (n = 60; 12,5%), ceftriaxona (n = 50; 10,6%) y ciprofloxacino (n = 50; 10,6%) y los más consumidos en DDD/1000 camas/día fueron: meropenem, fluconazol, vancomicina, ciprofloxacino, piperacilina sódica + tazobactam sódico y polimixina B. El probable diagnóstico infeccioso, que justificó la solicitud de antimicrobiano, fue sepsis (n = 124; 25,9%). La mayoría de los pacientes tenían indicación empírica de medicación (n = 396; 82,7%). Los agentes infecciosos, aislados en exámenes de cultivo, fueron más incidentes: acinetobacter baumanni y pseudomonas aeruginosa. En vista de los resultados, los principales cambios se establecieron en los componentes del formulario de solicitud de antimicrobianos para uso terapéutico. Conclusión: Esta investigación propuso la reestructuración de la forma de antimicrobianos para uso terapéutico, con el fin de aumentar el control del uso de medicamentos de uso restringido. Una vez en uso, contribuirá a la optimización del uso racional de los antimicrobianos. La implementación del formulario adaptado, resultante como producto de esta investigación, podrá extenderse como sugerencia a los profesionales de instituciones hospitalarias que estén interesados en iniciar acciones congruentes con el programa de gestión del uso de antimicrobianos.Objetivo: Implementar reformulação do formulário de antimicrobianos de uso terapêutico utilizada pelo HOL (Hospital Ophir Loyola), com foco no uso racional dos antimicrobianos de uso restrito no Centro de Terapia Intensiva (CTI). Métodos: Trata-se de uma pesquisa quali-quantitativa, de natureza transversal e caráter retrospectivo, por meio de coleta de dados, utilizando-se formulários de solicitação de antimicrobianos de uso terapêutico restrito, no período de agosto a dezembro de 2018. Resultados: Foram avaliados 479 formulários de solicitação de antimicrobianos de uso terapêutico restrito no CTI. Os principais antimicrobianos prescritos foram: meropenem (n = 79; 16.5%), vancomicina (n = 60; 12.7%), piperacilina sódica + tazobactam sódico (n = 60; 12.5%), da ceftriaxona (n = 50; 10.6%) e ciprofloxacino (n = 50; 10.6%) e os mais consumidos em DDD/1000 leitos/dia foram: meropenem, fluconazol, vancomicina, ciprofloxacino, piperacilina sódica + tazobactam sódico e polimixina B. O provável diagnóstico infeccioso, justificando a solicitação do antimicrobiano, foi a sepse (n = 124; 25.9%). A maioria dos pacientes tiveram indicação medicamentosa de forma empírica (n = 396; 82.7%). Os agentes infecciosos, isolados em exames de cultura, mais incidentes foram: acinetobacter baumanni e pseudomonas aeruginosa. Diante dos resultados, foram estabelecidas as principais alterações nos componentes do formulário de solicitação de antimicrobianos de uso terapêutico. Conclusão: Esta pesquisa propôs a reestruturação do formulário de antimicrobianos de uso terapêutico, a fim de aumentar o controle do uso de medicamentos de uso restrito. Uma vez em uso, contribuirá para otimização da utilização racional de antimicrobianos. A implantação do formulário adaptado, resultante como produto desta pesquisa, poderá ser estendido como sugestão para os profissionais de instituições hospitalares que vierem a apresentar interesse em iniciar ações condizentes ao programa de gerenciamento de uso de antimicrobianos.Research, Society and Development2022-05-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2793710.33448/rsd-v11i6.27937Research, Society and Development; Vol. 11 No. 6; e41611627937Research, Society and Development; Vol. 11 Núm. 6; e41611627937Research, Society and Development; v. 11 n. 6; e416116279372525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/27937/25354Copyright (c) 2022 Annie Elisandra Mesquita de Oliveira; Valéria Regina Cavalcante dos Santos https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOliveira, Annie Elisandra Mesquita de Santos , Valéria Regina Cavalcante dos 2022-05-13T18:04:10Zoai:ojs.pkp.sfu.ca:article/27937Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:45:30.783259Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Strategies for rationalizing antimicrobials in a high-complexity oncology care center
Estrategias para la racionalización de antimicrobianos en un centro de atención oncológica de alta complejidad
Estratégias para racionalização de antimicrobianos em um centro de assistência de alta complexidade em oncologia
title Strategies for rationalizing antimicrobials in a high-complexity oncology care center
spellingShingle Strategies for rationalizing antimicrobials in a high-complexity oncology care center
Oliveira, Annie Elisandra Mesquita de
Antimicrobianos
Resistência bacteriana
Gestão de antimicrobianos.
Antimicrobianos
Resistencia bacteriana
Manejo de antimicrobianos.
Antimicrobials
Bacterial resistance
Antimicrobial management.
title_short Strategies for rationalizing antimicrobials in a high-complexity oncology care center
title_full Strategies for rationalizing antimicrobials in a high-complexity oncology care center
title_fullStr Strategies for rationalizing antimicrobials in a high-complexity oncology care center
title_full_unstemmed Strategies for rationalizing antimicrobials in a high-complexity oncology care center
title_sort Strategies for rationalizing antimicrobials in a high-complexity oncology care center
author Oliveira, Annie Elisandra Mesquita de
author_facet Oliveira, Annie Elisandra Mesquita de
Santos , Valéria Regina Cavalcante dos
author_role author
author2 Santos , Valéria Regina Cavalcante dos
author2_role author
dc.contributor.author.fl_str_mv Oliveira, Annie Elisandra Mesquita de
Santos , Valéria Regina Cavalcante dos
dc.subject.por.fl_str_mv Antimicrobianos
Resistência bacteriana
Gestão de antimicrobianos.
Antimicrobianos
Resistencia bacteriana
Manejo de antimicrobianos.
Antimicrobials
Bacterial resistance
Antimicrobial management.
topic Antimicrobianos
Resistência bacteriana
Gestão de antimicrobianos.
Antimicrobianos
Resistencia bacteriana
Manejo de antimicrobianos.
Antimicrobials
Bacterial resistance
Antimicrobial management.
description Objective: Implement a reformulation of the therapeutic use antimicrobial form used by the HOL (Hospital Ophir Loyola), focusing on the rational use of restricted use antimicrobials in the Intensive Care Center (ICU). Methods: This is a quali-quantitative, cross-sectional and retrospective study, through data collection, using application forms for antimicrobials for restricted therapeutic use, from August to December 2018. Results: A total of 479 forms of request for antimicrobials for restricted therapeutic use in the ICU were evaluated. The main antimicrobials prescribed were: meropenem (n = 79; 16.5%), vancomycin (n = 60; 12.7%), piperacillin sodium + tazobactam sodium (n = 60; 12.5%), ceftriaxone (n = 50; 10.6%) and ciprofloxacin (n = 50; 10.6%) and the most consumed in DDD/1000 beds/day were: meropenem, fluconazole, vancomycin, ciprofloxacin, sodium piperacillin + sodium tazobactam and polymyxin B. The probable infectious diagnosis, justifying the antimicrobial request was sepsis (n = 124; 25.9%). Most patients were empirically indicated for medication (n = 396; 82.7%). The infectious agents, isolated in culture exams, more incidents were: acinetobacter baumanni and pseudomonas aeruginosa. In view of the results, the main changes were established in the components of the request form for antimicrobials for therapeutic use. Conclusion: This research proposed the restructuring of the form of antimicrobials for therapeutic use, in order to increase the control of the use of drugs of restricted use. Once in use, it will contribute to the optimization of the rational use of antimicrobials. The implementation of the adapted form, resulting as a product of this research, may be extended as a suggestion to professionals from hospital institutions who may be interested in initiating actions consistent with the antimicrobial use management program.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-02
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/27937
10.33448/rsd-v11i6.27937
url https://rsdjournal.org/index.php/rsd/article/view/27937
identifier_str_mv 10.33448/rsd-v11i6.27937
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/27937/25354
dc.rights.driver.fl_str_mv Copyright (c) 2022 Annie Elisandra Mesquita de Oliveira; Valéria Regina Cavalcante dos Santos
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Annie Elisandra Mesquita de Oliveira; Valéria Regina Cavalcante dos Santos
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 6; e41611627937
Research, Society and Development; Vol. 11 Núm. 6; e41611627937
Research, Society and Development; v. 11 n. 6; e41611627937
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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