Association of serum vitamin D3 levels and oral diseases - Systematic Review
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/23019 |
Resumo: | The active metabolite of vitamin D3, cholecalciferol, is a multifunctional hormone that acts in the regulation of calcium and phosphorus homeostasis and which, in addition, has shown promising results as an immunomodulator, an antitumor agent, among other functions. Therefore, this systematic review aims to review in the scientific literature how cholecalciferol acts as a hormonal modulator and what is its role in oral pathologies. A search was carried out in the PubMed (MEDLINE), Scopus, Embase, Google Scholar and The Cochrane Library databases, having as inclusion criteria studies which will use issues related to oral health associated with the use of cholecalciferol. We found several oral pathologies that are associated with cholecalciferol, and we verified its role in inflammation, chemoprevention and as an antitumor agent, we also revealed that low levels of this vitamin are associated with the appearance and/or predisposition of oral pathologies. We conclude that maintaining optimal serum cholecalciferol levels is very important for the preservation and maintenance of oral health as well as systemic health. |
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Association of serum vitamin D3 levels and oral diseases - Systematic ReviewAsociación de niveles séricos de vitamina D3 y enfermedades bucales - Revisión SistemáticaAssociação de níveis séricos de vitamina D3 e doenças orais – Revisão SistemáticaColecalciferolVitamin D3Mouth diseases.ColecalciferolVitamina D3Enfermedades de la boca.ColecalciferolVitamina D3Doenças bucais.The active metabolite of vitamin D3, cholecalciferol, is a multifunctional hormone that acts in the regulation of calcium and phosphorus homeostasis and which, in addition, has shown promising results as an immunomodulator, an antitumor agent, among other functions. Therefore, this systematic review aims to review in the scientific literature how cholecalciferol acts as a hormonal modulator and what is its role in oral pathologies. A search was carried out in the PubMed (MEDLINE), Scopus, Embase, Google Scholar and The Cochrane Library databases, having as inclusion criteria studies which will use issues related to oral health associated with the use of cholecalciferol. We found several oral pathologies that are associated with cholecalciferol, and we verified its role in inflammation, chemoprevention and as an antitumor agent, we also revealed that low levels of this vitamin are associated with the appearance and/or predisposition of oral pathologies. We conclude that maintaining optimal serum cholecalciferol levels is very important for the preservation and maintenance of oral health as well as systemic health.El metabolito activo de la vitamina D3, colecalciferol, es una hormona multifuncional que actúa en la regulación de la homeostasis del calcio y fósforo y que, además, ha mostrado resultados prometedores como inmunomodulador, agente antitumoral, entre otras funciones. Por tanto, esta revisión sistemática tiene como objetivo revisar en la literatura científica cómo actúa el colecalciferol como modulador hormonal y cuál es su papel en las patologías bucales. Se realizó una búsqueda en las bases de datos PubMed (MEDLINE), Scopus, Embase, Google Scholar y The Cochrane Library, teniendo como criterios de inclusión estudios que utilizarán temas relacionados con la salud bucal asociados al uso de colecalciferol. Encontramos varias patologías bucales que se asocian con colecalciferol, y verificamos su papel en la inflamación, quimioprevención y como agente antitumoral, también revelamos que niveles bajos de esta vitamina se asocian con la aparición y / o predisposición de patologías bucales. Concluimos que mantener niveles óptimos de colecalciferol sérico es muy importante para la preservación y mantenimiento de la salud bucal, así como la salud sistémica.O metabólito ativo da vitamina D3, o colecalciferol, é um hormônio multifuncional, que atua na regulação da homeostase do cálcio e do fósforo e que além disso, vem mostrado resultados promissores como imunomodulador, agente antitumoral entre outras funções. Destarde, essa revisão sistemática objetiva revisar na literatura científica como o colecalciferol atua como modulador hormonal e qual é seu papel frente a patologias orais. Foi realizada uma busca nas bases de dados PubMed (MEDLINE), Scopus, Embase, Google Scholar e The Cochrane Library, tendo como critérios de inclusão estudos os quais recorrerão assuntos referente à saúde oral associada ao uso do colecalciferol. Encontramos várias patologias orais que fazem associação com o colecalciferol, e verificamos seu papel na inflamação, na quimioprevenção e como um agente antitumoral, revelamos também que níveis baixos dessa vitamina estão associados ao aparecimento e /ou predisposição de patologias orais. Concluímos que a manutenção de níveis séricos ideais de colecalciferol é muito importante para a preservação e manutenção saúde bucal assim como para a saúde sistêmica.Research, Society and Development2021-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2301910.33448/rsd-v10i15.23019Research, Society and Development; Vol. 10 No. 15; e481101523019Research, Society and Development; Vol. 10 Núm. 15; e481101523019Research, Society and Development; v. 10 n. 15; e4811015230192525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/23019/20518Copyright (c) 2021 Stephane Silva Santana; Ivânia Aparecida Pimenta Santos Silva; Gustavo Augusto Santos; Adriano Luís Pulquério de Almeida; Rodrigo Soares de Andradehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantana, Stephane Silva Silva, Ivânia Aparecida Pimenta Santos Santos, Gustavo Augusto Almeida, Adriano Luís Pulquério de Andrade, Rodrigo Soares de 2021-12-06T10:13:53Zoai:ojs.pkp.sfu.ca:article/23019Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:42:00.809575Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Association of serum vitamin D3 levels and oral diseases - Systematic Review Asociación de niveles séricos de vitamina D3 y enfermedades bucales - Revisión Sistemática Associação de níveis séricos de vitamina D3 e doenças orais – Revisão Sistemática |
title |
Association of serum vitamin D3 levels and oral diseases - Systematic Review |
spellingShingle |
Association of serum vitamin D3 levels and oral diseases - Systematic Review Santana, Stephane Silva Colecalciferol Vitamin D3 Mouth diseases. Colecalciferol Vitamina D3 Enfermedades de la boca. Colecalciferol Vitamina D3 Doenças bucais. |
title_short |
Association of serum vitamin D3 levels and oral diseases - Systematic Review |
title_full |
Association of serum vitamin D3 levels and oral diseases - Systematic Review |
title_fullStr |
Association of serum vitamin D3 levels and oral diseases - Systematic Review |
title_full_unstemmed |
Association of serum vitamin D3 levels and oral diseases - Systematic Review |
title_sort |
Association of serum vitamin D3 levels and oral diseases - Systematic Review |
author |
Santana, Stephane Silva |
author_facet |
Santana, Stephane Silva Silva, Ivânia Aparecida Pimenta Santos Santos, Gustavo Augusto Almeida, Adriano Luís Pulquério de Andrade, Rodrigo Soares de |
author_role |
author |
author2 |
Silva, Ivânia Aparecida Pimenta Santos Santos, Gustavo Augusto Almeida, Adriano Luís Pulquério de Andrade, Rodrigo Soares de |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Santana, Stephane Silva Silva, Ivânia Aparecida Pimenta Santos Santos, Gustavo Augusto Almeida, Adriano Luís Pulquério de Andrade, Rodrigo Soares de |
dc.subject.por.fl_str_mv |
Colecalciferol Vitamin D3 Mouth diseases. Colecalciferol Vitamina D3 Enfermedades de la boca. Colecalciferol Vitamina D3 Doenças bucais. |
topic |
Colecalciferol Vitamin D3 Mouth diseases. Colecalciferol Vitamina D3 Enfermedades de la boca. Colecalciferol Vitamina D3 Doenças bucais. |
description |
The active metabolite of vitamin D3, cholecalciferol, is a multifunctional hormone that acts in the regulation of calcium and phosphorus homeostasis and which, in addition, has shown promising results as an immunomodulator, an antitumor agent, among other functions. Therefore, this systematic review aims to review in the scientific literature how cholecalciferol acts as a hormonal modulator and what is its role in oral pathologies. A search was carried out in the PubMed (MEDLINE), Scopus, Embase, Google Scholar and The Cochrane Library databases, having as inclusion criteria studies which will use issues related to oral health associated with the use of cholecalciferol. We found several oral pathologies that are associated with cholecalciferol, and we verified its role in inflammation, chemoprevention and as an antitumor agent, we also revealed that low levels of this vitamin are associated with the appearance and/or predisposition of oral pathologies. We conclude that maintaining optimal serum cholecalciferol levels is very important for the preservation and maintenance of oral health as well as systemic health. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/23019 10.33448/rsd-v10i15.23019 |
url |
https://rsdjournal.org/index.php/rsd/article/view/23019 |
identifier_str_mv |
10.33448/rsd-v10i15.23019 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/23019/20518 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 15; e481101523019 Research, Society and Development; Vol. 10 Núm. 15; e481101523019 Research, Society and Development; v. 10 n. 15; e481101523019 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052758831923200 |