Kawasaki disease and its relationship to Covid-19
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/33948 |
Resumo: | Introduction: Children affected by Covid-19, the picture of hyperinflammation presented showed changes in the coronary arteries, characteristic of Kawasaki disease (KD). Children present with persistent high fever, rash, swelling of the extremities, non-purulent conjunctivitis, abdominal pain, vomiting, and diarrhea. Objective: to present the scientific evidence available so far, which brings an existing association between Kawasaki Covid-19 Disease in children. Methodology: This is a literature review carried out between June and July 2021, in the following databases: Virtual Health Library (VHL), Google Scholar, Scientific Electronic Library Online (SciELO) and National Library of Medicine (PubMed MEDLINE). Results and discussion: It is suggested that the mechanism of KD is based on an antibody-mediated post-inflammatory reaction, thus, the identification of viral replication was not truly relevant in these cases. In addition to the link between the Covid-19 pandemic and the increase in DK cases, another period where there was a peak in DK incidence was during the context of the H1N1 pandemic, suggesting that SARS-CoV-2 is not the only virus capable of trigger such emergence of Kawasaki disease. Conclusion: Despite the more severe manifestations in patients affected by Covid-19, the occurrence of KD associated with Covid-19 is not very frequent, however, it is important to be aware of the signs and symptoms of the disease in order to obtain the earliest possible diagnosis. and proceed with the appropriate treatment, in order to avoid the occurrence of complicated or aggravated clinical conditions. |
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Kawasaki disease and its relationship to Covid-19Enfermedad de Kawasaki y su relación con el Covid-19Doença de Kawasaki e sua relação com a Covid-19Covid-19La enfermedad de KawasakiEnfermedad multisistémicaNiños.Covid-19Kawasaki diseaseMultisystemic diseaseKids.Covid-19Doença de KawasakiDoença multissistêmicaCrianças.Introduction: Children affected by Covid-19, the picture of hyperinflammation presented showed changes in the coronary arteries, characteristic of Kawasaki disease (KD). Children present with persistent high fever, rash, swelling of the extremities, non-purulent conjunctivitis, abdominal pain, vomiting, and diarrhea. Objective: to present the scientific evidence available so far, which brings an existing association between Kawasaki Covid-19 Disease in children. Methodology: This is a literature review carried out between June and July 2021, in the following databases: Virtual Health Library (VHL), Google Scholar, Scientific Electronic Library Online (SciELO) and National Library of Medicine (PubMed MEDLINE). Results and discussion: It is suggested that the mechanism of KD is based on an antibody-mediated post-inflammatory reaction, thus, the identification of viral replication was not truly relevant in these cases. In addition to the link between the Covid-19 pandemic and the increase in DK cases, another period where there was a peak in DK incidence was during the context of the H1N1 pandemic, suggesting that SARS-CoV-2 is not the only virus capable of trigger such emergence of Kawasaki disease. Conclusion: Despite the more severe manifestations in patients affected by Covid-19, the occurrence of KD associated with Covid-19 is not very frequent, however, it is important to be aware of the signs and symptoms of the disease in order to obtain the earliest possible diagnosis. and proceed with the appropriate treatment, in order to avoid the occurrence of complicated or aggravated clinical conditions.Introducción: Niños afectados por Covid-19, el cuadro de hiperinflamación presentado mostró cambios en las arterias coronarias, característicos de la enfermedad de Kawasaki (KD). Los niños presentan fiebre alta persistente, erupción cutánea, hinchazón de las extremidades, conjuntivitis no purulenta, dolor abdominal, vómitos y diarrea. Objetivo: presentar la evidencia científica disponible hasta el momento, que trae una asociación existente entre la Enfermedad de Kawasaki Covid-19 en niños. Metodología: Se trata de una revisión de la literatura realizada entre junio y julio de 2021, en las siguientes bases de datos: Virtual Health Library (BVS), Google Scholar, Scientific Electronic Library Online (SciELO) y National Library of Medicine (PubMed MEDLINE). Resultados y discusión: Se sugiere que el mecanismo de KD se basa en una reacción posinflamatoria mediada por anticuerpos, por lo que la identificación de la replicación viral no fue realmente relevante en estos casos. Además del vínculo entre la pandemia de Covid-19 y el aumento de casos de DK, otro período en el que hubo un pico en la incidencia de DK fue durante el contexto de la pandemia H1N1, lo que sugiere que el SARS-CoV-2 no es el único virus capaz de desencadenar tal aparición de la enfermedad de Kawasaki. Conclusión: A pesar de las manifestaciones más graves en pacientes afectados por Covid-19, la ocurrencia de EK asociada a Covid-19 no es muy frecuente, sin embargo, es importante estar atento a los signos y síntomas de la enfermedad para poder obtener la diagnóstico lo más temprano posible y proceder con el tratamiento adecuado, con el fin de evitar la aparición de condiciones clínicas complicadas o agravadas.Introdução: Em crianças acometidas pela Covid-19, o quadro de hiperinflamação apresentado demonstrou alterações nas artérias coronárias, característica da doença de Kawasaki (DK). As crianças apresentam febre alta e persistente, erupções cutâneas, edema nas extremidades, conjuntivite não purulenta, dor abdominal, vômitos e diarreia. Objetivo: apresentar as evidências científicas disponíveis até o momento, que trazem uma associação existente entre a Doença de Kawasaki Covid-19 em crianças. Metodologia: Trata-se de uma revisão de literatura realizada entre os meses de junho e julho de 2021, nas seguintes bases de dados: Biblioteca Virtual em Saúde (BVS), Google Scholar, Scientific Electronic Library Online (SciELO) e National Library of Medicine (PubMed MEDLINE). Resultados e discussão: Sugere-se que o mecanismo da DK seja baseado em uma reação pós-inflamatória mediada por anticorpos, assim, a identificação da replicação viral não se mostrou verdadeiramente relevante nesses casos. Além da ligação da pandemia de Covid-19 e aumento dos casos de DK, outro período em que houve pico de incidência da DK foi durante o contexto da pandemia de H1N1, sugerindo que o SARS-CoV-2 não é o único vírus capaz de desencadear tal surgimento da doença de Kawasaki. Conclusão: Apesar das manifestações mais graves nos pacientes acometidos pelo Covid-19, a ocorrência da DK associada à Covid-19 não é muito frequente, no entanto, é importante estar atento aos sinais e sintomas da doença para se obter o diagnóstico mais precoce possível e proceder com o tratamento adequado, de forma a se evitar a ocorrência de quadros clínicos complicados ou agravados.Research, Society and Development2022-08-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3394810.33448/rsd-v11i11.33948Research, Society and Development; Vol. 11 No. 11; e490111133948Research, Society and Development; Vol. 11 Núm. 11; e490111133948Research, Society and Development; v. 11 n. 11; e4901111339482525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/33948/28636Copyright (c) 2022 Bárbara Queiroz de Figueiredo; Bárbara Ferreira de Brito; Eduarda Cristina Diel; Ítalo Íris Boiba Rodrigues da Cunha; Karine Felipe Martins; Keila Cristiane Batista do Valle; Liz Silva Loureiro; Sara Rosa Peixoto; Sarah Grace Alves Travasso; Luciana de Almeida Françahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFigueiredo, Bárbara Queiroz de Brito, Bárbara Ferreira de Diel, Eduarda CristinaCunha, Ítalo Íris Boiba Rodrigues da Martins, Karine FelipeValle, Keila Cristiane Batista do Loureiro, Liz SilvaPeixoto, Sara RosaTravasso, Sarah Grace AlvesFrança, Luciana de Almeida2022-09-05T13:24:46Zoai:ojs.pkp.sfu.ca:article/33948Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:49:26.476683Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Kawasaki disease and its relationship to Covid-19 Enfermedad de Kawasaki y su relación con el Covid-19 Doença de Kawasaki e sua relação com a Covid-19 |
title |
Kawasaki disease and its relationship to Covid-19 |
spellingShingle |
Kawasaki disease and its relationship to Covid-19 Figueiredo, Bárbara Queiroz de Covid-19 La enfermedad de Kawasaki Enfermedad multisistémica Niños. Covid-19 Kawasaki disease Multisystemic disease Kids. Covid-19 Doença de Kawasaki Doença multissistêmica Crianças. |
title_short |
Kawasaki disease and its relationship to Covid-19 |
title_full |
Kawasaki disease and its relationship to Covid-19 |
title_fullStr |
Kawasaki disease and its relationship to Covid-19 |
title_full_unstemmed |
Kawasaki disease and its relationship to Covid-19 |
title_sort |
Kawasaki disease and its relationship to Covid-19 |
author |
Figueiredo, Bárbara Queiroz de |
author_facet |
Figueiredo, Bárbara Queiroz de Brito, Bárbara Ferreira de Diel, Eduarda Cristina Cunha, Ítalo Íris Boiba Rodrigues da Martins, Karine Felipe Valle, Keila Cristiane Batista do Loureiro, Liz Silva Peixoto, Sara Rosa Travasso, Sarah Grace Alves França, Luciana de Almeida |
author_role |
author |
author2 |
Brito, Bárbara Ferreira de Diel, Eduarda Cristina Cunha, Ítalo Íris Boiba Rodrigues da Martins, Karine Felipe Valle, Keila Cristiane Batista do Loureiro, Liz Silva Peixoto, Sara Rosa Travasso, Sarah Grace Alves França, Luciana de Almeida |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Figueiredo, Bárbara Queiroz de Brito, Bárbara Ferreira de Diel, Eduarda Cristina Cunha, Ítalo Íris Boiba Rodrigues da Martins, Karine Felipe Valle, Keila Cristiane Batista do Loureiro, Liz Silva Peixoto, Sara Rosa Travasso, Sarah Grace Alves França, Luciana de Almeida |
dc.subject.por.fl_str_mv |
Covid-19 La enfermedad de Kawasaki Enfermedad multisistémica Niños. Covid-19 Kawasaki disease Multisystemic disease Kids. Covid-19 Doença de Kawasaki Doença multissistêmica Crianças. |
topic |
Covid-19 La enfermedad de Kawasaki Enfermedad multisistémica Niños. Covid-19 Kawasaki disease Multisystemic disease Kids. Covid-19 Doença de Kawasaki Doença multissistêmica Crianças. |
description |
Introduction: Children affected by Covid-19, the picture of hyperinflammation presented showed changes in the coronary arteries, characteristic of Kawasaki disease (KD). Children present with persistent high fever, rash, swelling of the extremities, non-purulent conjunctivitis, abdominal pain, vomiting, and diarrhea. Objective: to present the scientific evidence available so far, which brings an existing association between Kawasaki Covid-19 Disease in children. Methodology: This is a literature review carried out between June and July 2021, in the following databases: Virtual Health Library (VHL), Google Scholar, Scientific Electronic Library Online (SciELO) and National Library of Medicine (PubMed MEDLINE). Results and discussion: It is suggested that the mechanism of KD is based on an antibody-mediated post-inflammatory reaction, thus, the identification of viral replication was not truly relevant in these cases. In addition to the link between the Covid-19 pandemic and the increase in DK cases, another period where there was a peak in DK incidence was during the context of the H1N1 pandemic, suggesting that SARS-CoV-2 is not the only virus capable of trigger such emergence of Kawasaki disease. Conclusion: Despite the more severe manifestations in patients affected by Covid-19, the occurrence of KD associated with Covid-19 is not very frequent, however, it is important to be aware of the signs and symptoms of the disease in order to obtain the earliest possible diagnosis. and proceed with the appropriate treatment, in order to avoid the occurrence of complicated or aggravated clinical conditions. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-08-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/33948 10.33448/rsd-v11i11.33948 |
url |
https://rsdjournal.org/index.php/rsd/article/view/33948 |
identifier_str_mv |
10.33448/rsd-v11i11.33948 |
dc.language.iso.fl_str_mv |
por |
language |
por |
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https://rsdjournal.org/index.php/rsd/article/view/33948/28636 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
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Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 11; e490111133948 Research, Society and Development; Vol. 11 Núm. 11; e490111133948 Research, Society and Development; v. 11 n. 11; e490111133948 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052721731207168 |