Vitamin E as a protective factor against neurological diseases
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/26838 |
Resumo: | Despite being an essential nutrient for humans, unlike most nutrients, the vitamin E does not have a specific role in metabolic functions, but the deficiency can cause a number of symptoms that include progressive neurological disorder, spinocerebellar ataxia, and death of peripheral nerves, specifically sensory neurons. This present investigation is a systematic review that aimed to elucidate the influence and role of vitamin E in the preservation of human neurological health, as well as probable neuroprotective mechanisms related to nutritional deficiency, increment of vitamin E in the diet and improvement of the quality of life in patients with neurological disorders. For the selection of articles, were selected the databases Scientific Electronic Library Online (SciELO), Virtual Health Library Portal (BVS) and Elsevier, in addition to articles published in the last five years. After analyzing the articles included in this review, the results of the studies showed that vitamin E is associated with improvement and prevention of several neurological disorders, such as Parkinson's disease, Alzheimer's disease, effects on synaptic plasticity and cognitive function in the hippocampus after traumatic brain injury, cognitive deficit in hypothyroidism and also had a protective role in neural tube development in mouse fetuses. |
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Vitamin E as a protective factor against neurological diseasesLa Vitamina E como factor protector ante enfermedades neurológicasVitamina E como um fator de proteção contra doenças neurológicasTocoferolDoenças DegenerativasNeurologiaEnsaios clínicosDemência.TocoferolEnfermedades degenerativasNeurologíaEnsayos clínicosLocura.TocopherolDegenerative DiseasesNeurologyClinical trialsInsanity.Despite being an essential nutrient for humans, unlike most nutrients, the vitamin E does not have a specific role in metabolic functions, but the deficiency can cause a number of symptoms that include progressive neurological disorder, spinocerebellar ataxia, and death of peripheral nerves, specifically sensory neurons. This present investigation is a systematic review that aimed to elucidate the influence and role of vitamin E in the preservation of human neurological health, as well as probable neuroprotective mechanisms related to nutritional deficiency, increment of vitamin E in the diet and improvement of the quality of life in patients with neurological disorders. For the selection of articles, were selected the databases Scientific Electronic Library Online (SciELO), Virtual Health Library Portal (BVS) and Elsevier, in addition to articles published in the last five years. After analyzing the articles included in this review, the results of the studies showed that vitamin E is associated with improvement and prevention of several neurological disorders, such as Parkinson's disease, Alzheimer's disease, effects on synaptic plasticity and cognitive function in the hippocampus after traumatic brain injury, cognitive deficit in hypothyroidism and also had a protective role in neural tube development in mouse fetuses.A pesar de ser un nutriente esencial para el ser humano, la vitamina E, a diferencia de la mayoría de los nutrientes, no tiene un papel específico en las funciones metabólicas, pero la deficiencia puede causar una serie de síntomas que incluyen trastorno neurológico progresivo, ataxia espinocerebelosa y muerte de los nervios periféricos, específicamente neuronas sensoriales. La presente investigación es una revisión sistemática que tuvo como objetivo dilucidar la influencia y el papel de la vitamina E en la preservación de la salud neurológica humana, así como probables mecanismos neuroprotectores relacionados con la deficiencia nutricional, incremento de vitamina E en la dieta y mejora de la calidad de vida en pacientes con trastornos neurológicos. Para la selección de artículos se seleccionaron las bases de datos Scientific Electronic Library Online (SciELO), Virtual Health Library Portal (BVS) y Elsevier y se seleccionaron artículos publicados en los últimos cinco años. Tras analizar los artículos incluidos en la revisión, los resultados de los estudios mostraron que la vitamina E está asociada con la mejora y prevención de varios trastornos neurológicos, como la enfermedad de Parkinson, la enfermedad de Alzheimer, efectos sobre la plasticidad sináptica y la función cognitiva en el hipocampo después de un traumatismo craneoencefálico, convulsiones, déficit cognitivo en el hipotiroidismo y también tuvo un papel protector en el desarrollo del tubo neural en fetos de ratón.Apesar de ser um nutriente essencial para os humanos, a vitamina E, ao contrário da maioria dos nutrientes, não tem um papel específico nas funções metabólicas, porém a deficiência pode causar vários sintomas que incluem distúrbio neurológico progressivo, ataxia espinocerebelar e morte de nervos periféricos, especificamente neurônios sensoriais. A presente investigação é uma revisão integrativa que teve como objetivo elucidar a influência e o papel da vitamina E na preservação da saúde neurológica humana, bem como prováveis mecanismos neuroprotetores relacionados com a carência nutricional, incremento da vitamina E na dieta e melhoria da qualidade de vida em pacientes com distúrbios neurológicos. Para a seleção dos artigos utilizou-se as bases de dados Scientific Eletronic Library Online (SciELO), Portal da Biblioteca Virtual de Saúde (BVS) e Elsevier e foram selecionados artigos publicados nos últimos cinco anos. Após análise dos artigos incluídos nesta revisão, os resultados dos estudos apontaram que a vitamina E está associada com a melhora e prevenção de várias desordens neurológicas, como a Doença de Parkinson, Doença de Alzheimer, efeitos na plasticidade sináptica e função cognitiva no hipocampo pós lesão cerebral traumática, convulsões, déficit cognitivo no hipotireoidismo e também apresentou papel protetivo no desenvolvimento do tubo neural em fetos de camundongos.Research, Society and Development2022-03-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2683810.33448/rsd-v11i3.26838Research, Society and Development; Vol. 11 No. 3; e57011326838Research, Society and Development; Vol. 11 Núm. 3; e57011326838Research, Society and Development; v. 11 n. 3; e570113268382525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/26838/23575Copyright (c) 2022 Letícia Caroline Gomes Martins; Adriana Sousa e Silva Carvalho; Fabiana Viana Nunes; Lucas Silva Peixoto; Mariana Pereira Ribeiro; Geovana Rocha Plácidohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMartins, Letícia Caroline GomesCarvalho, Adriana Sousa e SilvaNunes, Fabiana VianaPeixoto, Lucas SilvaRibeiro, Mariana PereiraPlácido, Geovana Rocha2022-03-09T13:44:38Zoai:ojs.pkp.sfu.ca:article/26838Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:46.659247Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Vitamin E as a protective factor against neurological diseases La Vitamina E como factor protector ante enfermedades neurológicas Vitamina E como um fator de proteção contra doenças neurológicas |
| title |
Vitamin E as a protective factor against neurological diseases |
| spellingShingle |
Vitamin E as a protective factor against neurological diseases Martins, Letícia Caroline Gomes Tocoferol Doenças Degenerativas Neurologia Ensaios clínicos Demência. Tocoferol Enfermedades degenerativas Neurología Ensayos clínicos Locura. Tocopherol Degenerative Diseases Neurology Clinical trials Insanity. |
| title_short |
Vitamin E as a protective factor against neurological diseases |
| title_full |
Vitamin E as a protective factor against neurological diseases |
| title_fullStr |
Vitamin E as a protective factor against neurological diseases |
| title_full_unstemmed |
Vitamin E as a protective factor against neurological diseases |
| title_sort |
Vitamin E as a protective factor against neurological diseases |
| author |
Martins, Letícia Caroline Gomes |
| author_facet |
Martins, Letícia Caroline Gomes Carvalho, Adriana Sousa e Silva Nunes, Fabiana Viana Peixoto, Lucas Silva Ribeiro, Mariana Pereira Plácido, Geovana Rocha |
| author_role |
author |
| author2 |
Carvalho, Adriana Sousa e Silva Nunes, Fabiana Viana Peixoto, Lucas Silva Ribeiro, Mariana Pereira Plácido, Geovana Rocha |
| author2_role |
author author author author author |
| dc.contributor.author.fl_str_mv |
Martins, Letícia Caroline Gomes Carvalho, Adriana Sousa e Silva Nunes, Fabiana Viana Peixoto, Lucas Silva Ribeiro, Mariana Pereira Plácido, Geovana Rocha |
| dc.subject.por.fl_str_mv |
Tocoferol Doenças Degenerativas Neurologia Ensaios clínicos Demência. Tocoferol Enfermedades degenerativas Neurología Ensayos clínicos Locura. Tocopherol Degenerative Diseases Neurology Clinical trials Insanity. |
| topic |
Tocoferol Doenças Degenerativas Neurologia Ensaios clínicos Demência. Tocoferol Enfermedades degenerativas Neurología Ensayos clínicos Locura. Tocopherol Degenerative Diseases Neurology Clinical trials Insanity. |
| description |
Despite being an essential nutrient for humans, unlike most nutrients, the vitamin E does not have a specific role in metabolic functions, but the deficiency can cause a number of symptoms that include progressive neurological disorder, spinocerebellar ataxia, and death of peripheral nerves, specifically sensory neurons. This present investigation is a systematic review that aimed to elucidate the influence and role of vitamin E in the preservation of human neurological health, as well as probable neuroprotective mechanisms related to nutritional deficiency, increment of vitamin E in the diet and improvement of the quality of life in patients with neurological disorders. For the selection of articles, were selected the databases Scientific Electronic Library Online (SciELO), Virtual Health Library Portal (BVS) and Elsevier, in addition to articles published in the last five years. After analyzing the articles included in this review, the results of the studies showed that vitamin E is associated with improvement and prevention of several neurological disorders, such as Parkinson's disease, Alzheimer's disease, effects on synaptic plasticity and cognitive function in the hippocampus after traumatic brain injury, cognitive deficit in hypothyroidism and also had a protective role in neural tube development in mouse fetuses. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-03-08 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/26838 10.33448/rsd-v11i3.26838 |
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https://rsdjournal.org/index.php/rsd/article/view/26838 |
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10.33448/rsd-v11i3.26838 |
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por |
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por |
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https://rsdjournal.org/index.php/rsd/article/view/26838/23575 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 11 No. 3; e57011326838 Research, Society and Development; Vol. 11 Núm. 3; e57011326838 Research, Society and Development; v. 11 n. 3; e57011326838 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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