Diagnosis, classification and monitoring of leukemia based on Raman spectroscopy

Detalhes bibliográficos
Autor(a) principal: Lima, Ana Mara Ferreira
Data de Publicação: 2021
Outros Autores: Silva, Janyersson Dannys Pereira da, Daniel, Camila Ribeiro
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/21657
Resumo: The diagnosis, classification and monitoring of leukemia requires the use and combination of various technologies usually involving staining and examining the morphology of cells in a blood sample or selective detection of specific cell membrane antigens. Raman spectroscopy is an optical technique based on the inelastic scattering of light by molecules and can provide highly specific biochemical information with minimal or no sample pretreatment. Based on this, the present study aimed to carry out a systematic review through the survey of peaks and markers in experimental and clinical studies about the use of Raman spectroscopy in the diagnosis and classification of leukemia. With the analysis of the selected studies, it was possible to show great progress in research on the applicability of Raman spectroscopy in diagnosis, in particular on its specificity and sensitivity, to ensure the differentiation between the four main subtypes of leukemia: chronic lymphoid leukemia (CLL), acute lymphoid leukemia (ALL), chronic myeloid leukemia (CML) and acute myeloid leukemia (AML).
id UNIFEI_bf27b1e6263f47401120a975840a31a6
oai_identifier_str oai:ojs.pkp.sfu.ca:article/21657
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Diagnosis, classification and monitoring of leukemia based on Raman spectroscopy Diagnóstico, clasificación y seguimiento de la leucemia basado en espectroscopia RamanDiagnóstico, classificação e monitoramento de leucemias baseado em espectroscopia Raman Espectroscopia RamanDiagnósticoLeucemia.Espectroscopia RamanDiagnósticoLeucemia.Raman spectroscopyDiagnosisLeukemia.The diagnosis, classification and monitoring of leukemia requires the use and combination of various technologies usually involving staining and examining the morphology of cells in a blood sample or selective detection of specific cell membrane antigens. Raman spectroscopy is an optical technique based on the inelastic scattering of light by molecules and can provide highly specific biochemical information with minimal or no sample pretreatment. Based on this, the present study aimed to carry out a systematic review through the survey of peaks and markers in experimental and clinical studies about the use of Raman spectroscopy in the diagnosis and classification of leukemia. With the analysis of the selected studies, it was possible to show great progress in research on the applicability of Raman spectroscopy in diagnosis, in particular on its specificity and sensitivity, to ensure the differentiation between the four main subtypes of leukemia: chronic lymphoid leukemia (CLL), acute lymphoid leukemia (ALL), chronic myeloid leukemia (CML) and acute myeloid leukemia (AML).El diagnóstico, la clasificación y el seguimiento de la leucemia requiere el uso y la combinación de varias tecnologías que normalmente implican la coloración y el examen de la morfología de las células en una muestra de sangre o la detección selectiva de antígenos específicos de la membrana celular. La espectroscopia Raman es una técnica óptica basada en la dispersión inelástica de luz por las moléculas y puede proporcionar información bioquímica detallada con un pretratamiento mínimo o nulo de la muestra. En base a esto, el presente estudio tuvo como objetivo realizar una revisión sistemática a través del relevamiento de picos y marcadores en estudios experimentales y clínicos sobre la utilización de la espectroscopia Raman en el diagnóstico y clasificación de la leucemia. El análisis de los estudios seleccionados ha evidenciado un gran avance en la investigación sobre la aplicabilidad de la espectroscopia Raman en el diagnóstico, en particular en su especificidad y sensibilidad, para asegurar la diferenciación entre los cuatro principales subtipos de leucemia: leucemia linfoide crónica, leucemia linfoide aguda, leucemia mieloide crónica y leucemia mieloide aguda.O diagnóstico, classificação e monitoramento de leucemia requerem o uso e a combinação de várias tecnologias geralmente envolvendo coloração e exame da morfologia das células em uma amostra de sangue ou detecção seletiva de antígenos específicos da membrana celular. A espectroscopia Raman é uma técnica óptica baseada no espalhamento inelástico de luz por moléculas e pode fornecer informações bioquímicas altamente específicas com mínimo ou nenhum pré-tratamento de amostra. Com base nisso o presente estudo teve como objetivo realizar uma revisão sistemática por meio do levantamento de picos e marcadores em estudos experimentais e clínicos acerca do emprego da espectroscopia Raman no diagnóstico e a classificação da leucemia. Com a análise dos estudos selecionados foi possível evidenciar um grande progresso nas pesquisas sobre a aplicabilidade da espectroscopia Raman no diagnóstico, em especial sobre a sua especificidade e sensibilidade, para garantir a diferenciação entre os quatro principais subtipos de leucemias: leucemia linfoide crônica (LLC), leucemia linfoide aguda (LLA), leucemia mieloide crônica (LMC) e leucemia mieloide aguda (LMA). Research, Society and Development2021-10-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2165710.33448/rsd-v10i14.21657Research, Society and Development; Vol. 10 No. 14; e67101421657Research, Society and Development; Vol. 10 Núm. 14; e67101421657Research, Society and Development; v. 10 n. 14; e671014216572525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/21657/19350Copyright (c) 2021 Ana Mara Ferreira Lima; Janyersson Dannys Pereira da Silva; Camila Ribeiro Danielhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLima, Ana Mara Ferreira Silva, Janyersson Dannys Pereira da Daniel, Camila Ribeiro 2021-12-04T11:48:39Zoai:ojs.pkp.sfu.ca:article/21657Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:41:01.893470Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Diagnosis, classification and monitoring of leukemia based on Raman spectroscopy
Diagnóstico, clasificación y seguimiento de la leucemia basado en espectroscopia Raman
Diagnóstico, classificação e monitoramento de leucemias baseado em espectroscopia Raman
title Diagnosis, classification and monitoring of leukemia based on Raman spectroscopy
spellingShingle Diagnosis, classification and monitoring of leukemia based on Raman spectroscopy
Lima, Ana Mara Ferreira
Espectroscopia Raman
Diagnóstico
Leucemia.
Espectroscopia Raman
Diagnóstico
Leucemia.
Raman spectroscopy
Diagnosis
Leukemia.
title_short Diagnosis, classification and monitoring of leukemia based on Raman spectroscopy
title_full Diagnosis, classification and monitoring of leukemia based on Raman spectroscopy
title_fullStr Diagnosis, classification and monitoring of leukemia based on Raman spectroscopy
title_full_unstemmed Diagnosis, classification and monitoring of leukemia based on Raman spectroscopy
title_sort Diagnosis, classification and monitoring of leukemia based on Raman spectroscopy
author Lima, Ana Mara Ferreira
author_facet Lima, Ana Mara Ferreira
Silva, Janyersson Dannys Pereira da
Daniel, Camila Ribeiro
author_role author
author2 Silva, Janyersson Dannys Pereira da
Daniel, Camila Ribeiro
author2_role author
author
dc.contributor.author.fl_str_mv Lima, Ana Mara Ferreira
Silva, Janyersson Dannys Pereira da
Daniel, Camila Ribeiro
dc.subject.por.fl_str_mv Espectroscopia Raman
Diagnóstico
Leucemia.
Espectroscopia Raman
Diagnóstico
Leucemia.
Raman spectroscopy
Diagnosis
Leukemia.
topic Espectroscopia Raman
Diagnóstico
Leucemia.
Espectroscopia Raman
Diagnóstico
Leucemia.
Raman spectroscopy
Diagnosis
Leukemia.
description The diagnosis, classification and monitoring of leukemia requires the use and combination of various technologies usually involving staining and examining the morphology of cells in a blood sample or selective detection of specific cell membrane antigens. Raman spectroscopy is an optical technique based on the inelastic scattering of light by molecules and can provide highly specific biochemical information with minimal or no sample pretreatment. Based on this, the present study aimed to carry out a systematic review through the survey of peaks and markers in experimental and clinical studies about the use of Raman spectroscopy in the diagnosis and classification of leukemia. With the analysis of the selected studies, it was possible to show great progress in research on the applicability of Raman spectroscopy in diagnosis, in particular on its specificity and sensitivity, to ensure the differentiation between the four main subtypes of leukemia: chronic lymphoid leukemia (CLL), acute lymphoid leukemia (ALL), chronic myeloid leukemia (CML) and acute myeloid leukemia (AML).
publishDate 2021
dc.date.none.fl_str_mv 2021-10-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/21657
10.33448/rsd-v10i14.21657
url https://rsdjournal.org/index.php/rsd/article/view/21657
identifier_str_mv 10.33448/rsd-v10i14.21657
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/21657/19350
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 14; e67101421657
Research, Society and Development; Vol. 10 Núm. 14; e67101421657
Research, Society and Development; v. 10 n. 14; e67101421657
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052819348389888

Registros relacionados