Development of a 3D polyetheretherketone structure that mimics the cranial bone morphology for use in cranioplasty
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/13336 |
Resumo: | Cranioencephalic traumatism (TBI) is a common situation in trauma hospitals and has become responsible for high rates of mortality worldwide. When the victim of TBI is affected by injuries to the skullcap with a need for grafting, problems regarding the availability of suitable and affordable materials eventually happen. In this study, a 3D structure of Polyetheretherketone (PEEK) that mimics the cranial bone morphology for use in cranioplasty was developed. Samples of different formulations, in the form of round bars, were obtained through uniaxial compression, and porosity was controlled by the salt leaching technique. Then, the specimens were characterized in terms of pore morphology and distribution, surface roughness, compression resistance and cytotoxicity. Results exhibited high levels of similarity of the 3D strutures of PEEK to the natural human bone, which indicates the effectiveness of the proposed method in mimicking the morphology of the compact/porous/compact system of the skullcap (diploe). |
id |
UNIFEI_bf4df498acb646b5e9f937ebfed21c46 |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/13336 |
network_acronym_str |
UNIFEI |
network_name_str |
Research, Society and Development |
repository_id_str |
|
spelling |
Development of a 3D polyetheretherketone structure that mimics the cranial bone morphology for use in cranioplastyDesarrollo de una estructura 3D de polieteretercetona similar a la morfología ósea craneal para su aplicación en la craneoplastiaDesenvolvimento de estrutura 3D de polieteretercetona semelhante a morfologia do osso craniano para uso em cranioplastia3D structurePolyetheretherketoneCranial boneSalt leaching technique.Estructura 3DPolieteretercetonaHueso cranealTécnica de lixiviación de sal.Estrutura 3DPolieteretercetonaOsso cranianoTécnica de lixiviação de sal.Cranioencephalic traumatism (TBI) is a common situation in trauma hospitals and has become responsible for high rates of mortality worldwide. When the victim of TBI is affected by injuries to the skullcap with a need for grafting, problems regarding the availability of suitable and affordable materials eventually happen. In this study, a 3D structure of Polyetheretherketone (PEEK) that mimics the cranial bone morphology for use in cranioplasty was developed. Samples of different formulations, in the form of round bars, were obtained through uniaxial compression, and porosity was controlled by the salt leaching technique. Then, the specimens were characterized in terms of pore morphology and distribution, surface roughness, compression resistance and cytotoxicity. Results exhibited high levels of similarity of the 3D strutures of PEEK to the natural human bone, which indicates the effectiveness of the proposed method in mimicking the morphology of the compact/porous/compact system of the skullcap (diploe).El traumatismo craneoencefálico (LCT) es una situación común en los hospitales de traumatología y se ha convertido en responsable de las altas tasas de mortalidad en todo el mundo. Cuando la víctima de TBI se ve afectada por lesiones en el casquete con la necesidad de un injerto, eventualmente surgen problemas con respecto a la disponibilidad de materiales adecuados y asequibles. En este estudio, se desarrolló una estructura 3D de polieteretercetona que imita la morfología del hueso craneal para su uso en craneoplastia. Se obtuvieron muestras de diferentes formulaciones, en forma de barras redondas, mediante compresión uniaxial y se controló la porosidad mediante la técnica de lixiviación de sales. Luego, las muestras se caracterizaron en términos de morfología y distribución de los poros, rugosidad superficial, resistencia a la compresión y citotoxicidad. Los resultados mostraron altos niveles de similitud de las muestras con el hueso humano natural, lo que indica la efectividad del método propuesto para imitar la morfología del sistema compacto/poroso/compacto del casquete (diploe).O traumatismo cranioencefálico (TCE) é uma situação comum em hospitais de trauma e tem se tornado responsável por altas taxas de mortalidade em todo o mundo. Quando a vítima de TCE é acometida por lesões na calota craniana com necessidade de enxerto, eventualmente surgem problemas de disponibilidade de materiais adequados e acessíveis. Neste estudo, foi desenvolvida uma estrutura 3D de Polieteretercetona (PEEK) que mimetiza a morfologia do osso craniano para uso em cranioplastia. Amostras de diferentes formulações, na forma de pastilhas redondas, foram obtidas por compressão uniaxial, e a porosidade foi controlada pela técnica de lixiviação de sal. Em seguida, os espécimes foram caracterizados quanto à morfologia e distribuição dos poros, rugosidade superficial, resistência à compressão e citotoxicidade. Os resultados exibiram altos níveis de similaridade das estruturas 3D de PEEK com o osso humano natural, o que indica a eficácia do método proposto em mimetizar a morfologia do sistema compacto/poroso/compacto da calota craniana (diploe).Research, Society and Development2021-03-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1333610.33448/rsd-v10i3.13336Research, Society and Development; Vol. 10 No. 3; e29810313336Research, Society and Development; Vol. 10 Núm. 3; e29810313336Research, Society and Development; v. 10 n. 3; e298103133362525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/13336/12007Copyright (c) 2021 Maria Dennise Medeiros Macedo; Claudio Orestes Britto Filho; Matheus Ferreira de Souza; Wladymyr Jefferson Bacalhau de Sousa; Thiago Caju Pedrosa; Ana Caroline Santana de Azevedo; Kleilton Oliveira Santos; Glauber Rodrigues Cerqueira de Cerqueira; Fernando Melo Gadelha; Marcus Vinicius Lia Fookhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMacedo, Maria Dennise MedeirosBritto Filho, Claudio OrestesSouza, Matheus Ferreira deSousa, Wladymyr Jefferson Bacalhau dePedrosa, Thiago CajuAzevedo, Ana Caroline Santana deSantos, Kleilton OliveiraCerqueira, Glauber Rodrigues Cerqueira deGadelha, Fernando Melo Fook, Marcus Vinicius Lia2021-03-28T12:03:35Zoai:ojs.pkp.sfu.ca:article/13336Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:34:42.110112Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Development of a 3D polyetheretherketone structure that mimics the cranial bone morphology for use in cranioplasty Desarrollo de una estructura 3D de polieteretercetona similar a la morfología ósea craneal para su aplicación en la craneoplastia Desenvolvimento de estrutura 3D de polieteretercetona semelhante a morfologia do osso craniano para uso em cranioplastia |
title |
Development of a 3D polyetheretherketone structure that mimics the cranial bone morphology for use in cranioplasty |
spellingShingle |
Development of a 3D polyetheretherketone structure that mimics the cranial bone morphology for use in cranioplasty Macedo, Maria Dennise Medeiros 3D structure Polyetheretherketone Cranial bone Salt leaching technique. Estructura 3D Polieteretercetona Hueso craneal Técnica de lixiviación de sal. Estrutura 3D Polieteretercetona Osso craniano Técnica de lixiviação de sal. |
title_short |
Development of a 3D polyetheretherketone structure that mimics the cranial bone morphology for use in cranioplasty |
title_full |
Development of a 3D polyetheretherketone structure that mimics the cranial bone morphology for use in cranioplasty |
title_fullStr |
Development of a 3D polyetheretherketone structure that mimics the cranial bone morphology for use in cranioplasty |
title_full_unstemmed |
Development of a 3D polyetheretherketone structure that mimics the cranial bone morphology for use in cranioplasty |
title_sort |
Development of a 3D polyetheretherketone structure that mimics the cranial bone morphology for use in cranioplasty |
author |
Macedo, Maria Dennise Medeiros |
author_facet |
Macedo, Maria Dennise Medeiros Britto Filho, Claudio Orestes Souza, Matheus Ferreira de Sousa, Wladymyr Jefferson Bacalhau de Pedrosa, Thiago Caju Azevedo, Ana Caroline Santana de Santos, Kleilton Oliveira Cerqueira, Glauber Rodrigues Cerqueira de Gadelha, Fernando Melo Fook, Marcus Vinicius Lia |
author_role |
author |
author2 |
Britto Filho, Claudio Orestes Souza, Matheus Ferreira de Sousa, Wladymyr Jefferson Bacalhau de Pedrosa, Thiago Caju Azevedo, Ana Caroline Santana de Santos, Kleilton Oliveira Cerqueira, Glauber Rodrigues Cerqueira de Gadelha, Fernando Melo Fook, Marcus Vinicius Lia |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Macedo, Maria Dennise Medeiros Britto Filho, Claudio Orestes Souza, Matheus Ferreira de Sousa, Wladymyr Jefferson Bacalhau de Pedrosa, Thiago Caju Azevedo, Ana Caroline Santana de Santos, Kleilton Oliveira Cerqueira, Glauber Rodrigues Cerqueira de Gadelha, Fernando Melo Fook, Marcus Vinicius Lia |
dc.subject.por.fl_str_mv |
3D structure Polyetheretherketone Cranial bone Salt leaching technique. Estructura 3D Polieteretercetona Hueso craneal Técnica de lixiviación de sal. Estrutura 3D Polieteretercetona Osso craniano Técnica de lixiviação de sal. |
topic |
3D structure Polyetheretherketone Cranial bone Salt leaching technique. Estructura 3D Polieteretercetona Hueso craneal Técnica de lixiviación de sal. Estrutura 3D Polieteretercetona Osso craniano Técnica de lixiviação de sal. |
description |
Cranioencephalic traumatism (TBI) is a common situation in trauma hospitals and has become responsible for high rates of mortality worldwide. When the victim of TBI is affected by injuries to the skullcap with a need for grafting, problems regarding the availability of suitable and affordable materials eventually happen. In this study, a 3D structure of Polyetheretherketone (PEEK) that mimics the cranial bone morphology for use in cranioplasty was developed. Samples of different formulations, in the form of round bars, were obtained through uniaxial compression, and porosity was controlled by the salt leaching technique. Then, the specimens were characterized in terms of pore morphology and distribution, surface roughness, compression resistance and cytotoxicity. Results exhibited high levels of similarity of the 3D strutures of PEEK to the natural human bone, which indicates the effectiveness of the proposed method in mimicking the morphology of the compact/porous/compact system of the skullcap (diploe). |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-03-16 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/13336 10.33448/rsd-v10i3.13336 |
url |
https://rsdjournal.org/index.php/rsd/article/view/13336 |
identifier_str_mv |
10.33448/rsd-v10i3.13336 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/13336/12007 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 3; e29810313336 Research, Society and Development; Vol. 10 Núm. 3; e29810313336 Research, Society and Development; v. 10 n. 3; e29810313336 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
_version_ |
1797052817374969856 |