Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions

Detalhes bibliográficos
Autor(a) principal: Oliveira, Évelin Cogo de
Data de Publicação: 2021
Outros Autores: Viana, Altevir Rossato, Serafin, Marissa Bolson, Pompeu, Lenise Deon, Manfron, Melania Palermo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
DOI: 10.33448/rsd-v10i16.23778
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/23778
Resumo: The medicinal species Glechon spathulata Benth, belonging to the family Lamiaceae, known as the "Mangeroninha-do-campo". The objective of the study was to evaluate the antimicrobial activity of the crude extract and fractions obtained in open - column chromatography of G. spathulata through the broth microdilution method, to test against different gram positive and gram-negative bacteria. According to the results obtained, the greatest inhibitory potential occurred against gram negative bacteria. The fractions C and E, G fraction and crude extract presented better results against gram negative bacteria, and the highest inhibitory potential occurred in relation to the two strains of Escherichia coli (ATCC 35218 and ATCC 25922). The crude extract and C and F fractions showed a greater inhibitory effect against Salmonella tiphymurium ATCC 52117. There was also an inhibitory potential against Staphylococcus aureus strains ATCC 25923, both for the crude extract, as well as fractions C and B And fractions F and G. Inhibition of Staphylococcus epidermidis strains ATCC 12228 occurred only in crude extract and ethyl acetate fractions. Both the crude extract and the fractions of G. spathulata presented a potential antibacterial activity. The extract and the fractions presented better activity against the strain of Salmonella tiphymurium when compared to studies that used the same plant and plants of the same family. This study showed that both the crude extract and some fractions of Glechon spathulata Benth are potential candidates for the development of new antimicrobial agents.
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spelling Antimicrobial activity of Glechon spathulata BENTH crude extract and fractionsActividad antimicrobiana del extracto crudo y fracciones de Glechon spathulata BENTHAtividade antimicrobiana do extrato bruto e frações de Glechon spathulata BENTHGlechon spathulataLamiaceaeMinimum Inhibitory ConcentrationGram positive and gram negative bactéria.Glechon spathulataLamiaceaeConcentración mínima inhibitoriaBacterias gram positivas y gram negativas.Glechon spathulataLamiaceaeConcentração Inibitória MínimaBactérias gram positivas e gram negativas.The medicinal species Glechon spathulata Benth, belonging to the family Lamiaceae, known as the "Mangeroninha-do-campo". The objective of the study was to evaluate the antimicrobial activity of the crude extract and fractions obtained in open - column chromatography of G. spathulata through the broth microdilution method, to test against different gram positive and gram-negative bacteria. According to the results obtained, the greatest inhibitory potential occurred against gram negative bacteria. The fractions C and E, G fraction and crude extract presented better results against gram negative bacteria, and the highest inhibitory potential occurred in relation to the two strains of Escherichia coli (ATCC 35218 and ATCC 25922). The crude extract and C and F fractions showed a greater inhibitory effect against Salmonella tiphymurium ATCC 52117. There was also an inhibitory potential against Staphylococcus aureus strains ATCC 25923, both for the crude extract, as well as fractions C and B And fractions F and G. Inhibition of Staphylococcus epidermidis strains ATCC 12228 occurred only in crude extract and ethyl acetate fractions. Both the crude extract and the fractions of G. spathulata presented a potential antibacterial activity. The extract and the fractions presented better activity against the strain of Salmonella tiphymurium when compared to studies that used the same plant and plants of the same family. This study showed that both the crude extract and some fractions of Glechon spathulata Benth are potential candidates for the development of new antimicrobial agents.La especie medicinal Glechon spathulata Benth perteneciente a la familia Lamiaceae, conocida como “Manjeroninha-do-campo”. El objetivo del estudio fue evaluar la actividad antimicrobiana del extracto crudo y fracciones obtenidas por cromatografía en columna abierta) de G. spathulata mediante el método de microdilución en caldo, para contrastar diferentes bacterias gram positivas y gram negativas. Según los resultados obtenidos, el mayor potencial inhibitorio se presentó frente a bacterias gram negativas. Las fracciones C y E, la fracción G y el extracto crudo mostraron mejores resultados contra bacterias gramnegativas, con el mayor potencial inhibitorio ocurriendo contra las cepas de Escherichia coli (ATCC 35218 y ATCC 25922). El extracto crudo y las fracciones C y F mostraron un mayor efecto inhibidor frente a Salmonella tiphymurium ATCC 52117. También existió un potencial inhibitorio frente a cepas de Staphylococcus aureus ATCC 25923, tanto para el extracto crudo como para las fracciones C y B y fracciones F y G. La inhibición de las cepas de Staphylococcus epidermidis ATCC 12228 se produjo sólo en el extracto crudo y en las fracciones de acetato de etilo. Tanto el extracto crudo como las fracciones de G. spathulata mostraron una potencial actividad antibacteriana. El extracto y las fracciones mostraron una mejor actividad contra la cepa de Salmonella tiphymurium en comparación con los estudios que utilizaron la misma planta y plantas de la misma familia. Este estudio mostró que tanto el extracto crudo como algunas fracciones de Gelchon spathulata Benth son candidatos potenciales para el desarrollo de nuevos agentes antimicrobianos.A espécie medicinal Glechon spathulata Benth pertencente à família Lamiaceae, conhecida como “Manjeroninha-do-campo”. O objetivo do estudo, foi avaliar a atividade antimicrobiana do extrato bruto e frações obtida em cromatografia em coluna aberta de G. spathulata através do método de microdiluição em caldo, para testar frente a diferentes bactérias gram positivas e gram negativas. De acordo com os resultados obtidos, o maior potencial inibitório ocorreu frente às bactérias gram negativas. As frações C e E, fração G e o extrato bruto apresentaram melhores resultados frente a bactérias gram negativas, sendo que o maior potencial inibitório ocorreu frente às duas cepas de Escherichia coli (ATCC 35218 e ATCC 25922). O extrato bruto e as frações C e F apresentaram um maior efeito inibitório frente à Salmonella tiphymurium ATCC 52117. Também houve um potencial inibitório frente às cepas de Staphylococcus aureus ATCC 25923, tanto pelo extrato bruto, como pelas frações C e B e frações F e G. A inibição das cepas de Staphylococcus epidermidis ATCC 12228 ocorreu somente no extrato bruto e nas frações de acetato de etila. Tanto o extrato bruto quanto as frações de G. spathulata apresentaram potencial atividade antibacteriana. O extrato e as frações apresentaram melhor atividade frente à cepa de Salmonella tiphymurium quando comparado a estudos que utilizaram a mesma planta e plantas da mesma família. Este estudo mostrou que tanto o extrato bruto, quanto algumas frações de Gelchon spathulata Benth são candidatos potenciais para o desenvolvimento de novos agentes antimicrobianos.Research, Society and Development2021-12-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2377810.33448/rsd-v10i16.23778Research, Society and Development; Vol. 10 No. 16; e247101623778Research, Society and Development; Vol. 10 Núm. 16; e247101623778Research, Society and Development; v. 10 n. 16; e2471016237782525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/23778/20905Copyright (c) 2021 Évelin Cogo de Oliveira; Altevir Rossato Viana; Marissa Bolson Serafin; Lenise Deon Pompeu; Melania Palermo Manfronhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOliveira, Évelin Cogo de Viana, Altevir Rossato Serafin, Marissa Bolson Pompeu, Lenise Deon Manfron, Melania Palermo 2021-12-20T11:03:07Zoai:ojs.pkp.sfu.ca:article/23778Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:42:32.356369Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
Actividad antimicrobiana del extracto crudo y fracciones de Glechon spathulata BENTH
Atividade antimicrobiana do extrato bruto e frações de Glechon spathulata BENTH
title Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
spellingShingle Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
Oliveira, Évelin Cogo de
Glechon spathulata
Lamiaceae
Minimum Inhibitory Concentration
Gram positive and gram negative bactéria.
Glechon spathulata
Lamiaceae
Concentración mínima inhibitoria
Bacterias gram positivas y gram negativas.
Glechon spathulata
Lamiaceae
Concentração Inibitória Mínima
Bactérias gram positivas e gram negativas.
Oliveira, Évelin Cogo de
Glechon spathulata
Lamiaceae
Minimum Inhibitory Concentration
Gram positive and gram negative bactéria.
Glechon spathulata
Lamiaceae
Concentración mínima inhibitoria
Bacterias gram positivas y gram negativas.
Glechon spathulata
Lamiaceae
Concentração Inibitória Mínima
Bactérias gram positivas e gram negativas.
title_short Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
title_full Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
title_fullStr Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
title_full_unstemmed Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
title_sort Antimicrobial activity of Glechon spathulata BENTH crude extract and fractions
author Oliveira, Évelin Cogo de
author_facet Oliveira, Évelin Cogo de
Oliveira, Évelin Cogo de
Viana, Altevir Rossato
Serafin, Marissa Bolson
Pompeu, Lenise Deon
Manfron, Melania Palermo
Viana, Altevir Rossato
Serafin, Marissa Bolson
Pompeu, Lenise Deon
Manfron, Melania Palermo
author_role author
author2 Viana, Altevir Rossato
Serafin, Marissa Bolson
Pompeu, Lenise Deon
Manfron, Melania Palermo
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Évelin Cogo de
Viana, Altevir Rossato
Serafin, Marissa Bolson
Pompeu, Lenise Deon
Manfron, Melania Palermo
dc.subject.por.fl_str_mv Glechon spathulata
Lamiaceae
Minimum Inhibitory Concentration
Gram positive and gram negative bactéria.
Glechon spathulata
Lamiaceae
Concentración mínima inhibitoria
Bacterias gram positivas y gram negativas.
Glechon spathulata
Lamiaceae
Concentração Inibitória Mínima
Bactérias gram positivas e gram negativas.
topic Glechon spathulata
Lamiaceae
Minimum Inhibitory Concentration
Gram positive and gram negative bactéria.
Glechon spathulata
Lamiaceae
Concentración mínima inhibitoria
Bacterias gram positivas y gram negativas.
Glechon spathulata
Lamiaceae
Concentração Inibitória Mínima
Bactérias gram positivas e gram negativas.
description The medicinal species Glechon spathulata Benth, belonging to the family Lamiaceae, known as the "Mangeroninha-do-campo". The objective of the study was to evaluate the antimicrobial activity of the crude extract and fractions obtained in open - column chromatography of G. spathulata through the broth microdilution method, to test against different gram positive and gram-negative bacteria. According to the results obtained, the greatest inhibitory potential occurred against gram negative bacteria. The fractions C and E, G fraction and crude extract presented better results against gram negative bacteria, and the highest inhibitory potential occurred in relation to the two strains of Escherichia coli (ATCC 35218 and ATCC 25922). The crude extract and C and F fractions showed a greater inhibitory effect against Salmonella tiphymurium ATCC 52117. There was also an inhibitory potential against Staphylococcus aureus strains ATCC 25923, both for the crude extract, as well as fractions C and B And fractions F and G. Inhibition of Staphylococcus epidermidis strains ATCC 12228 occurred only in crude extract and ethyl acetate fractions. Both the crude extract and the fractions of G. spathulata presented a potential antibacterial activity. The extract and the fractions presented better activity against the strain of Salmonella tiphymurium when compared to studies that used the same plant and plants of the same family. This study showed that both the crude extract and some fractions of Glechon spathulata Benth are potential candidates for the development of new antimicrobial agents.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-12
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/23778
10.33448/rsd-v10i16.23778
url https://rsdjournal.org/index.php/rsd/article/view/23778
identifier_str_mv 10.33448/rsd-v10i16.23778
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/23778/20905
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 16; e247101623778
Research, Society and Development; Vol. 10 Núm. 16; e247101623778
Research, Society and Development; v. 10 n. 16; e247101623778
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1822178625096515584
dc.identifier.doi.none.fl_str_mv 10.33448/rsd-v10i16.23778

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