Takotsubo syndrome in the context of the COVID-19 pandemic: An integrative review
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/36810 |
Resumo: | Introduction: Takotsubo syndrome (TTS) is characterized by a temporary left ventricular (LV) systolic dysfunction, usually in the context of acute physical or emotional stress. Thus, the stress mechanism generated by the pandemic and the COVID-19 infection has been related to this syndrome. Objective: To analyze, through a literature review, the relationship between COVID-19 and Takotsubo Syndrome, taking into account the pathophysiological mechanisms involved. Methods: This is a literature review with searches performed in July 2022, using the PubMed database. Results and Discussion: 29 articles were selected, after full evaluation, the main findings show an increase in the incidence of TTS in the general population and in patients with COVID-19. The pathophysiological mechanisms involved include the increase in catecholamines and cortisol, cytokine storm, microvascular dysfunction and the direct action of SARS-COV-2 on cardiomyocytes and endothelium, in addition to the psychological burden resulting from the pandemic. Conclusion: The incidence of stress-induced cardiomyopathy is expected to increase in the general population, driven by the psychosocial consequences of this period. Therefore, it is imperative that clinicians are familiar with the clinical presentation, possible complications, and management of TTS. |
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Takotsubo syndrome in the context of the COVID-19 pandemic: An integrative reviewSíndrome de Takotsubo en el contexto de la pandemia de COVID-19: Una revisión integradoraSíndrome de Takotsubo no contexto da pandemia de COVID-19: Uma revisão integrativaTakotsubo CardiomyopathyCOVID-19EpidemiologyPathophysiologyPsychological distress. Cardiomiopatia de TakotsuboCOVID-19EpidemiologíaFisiopatologíaDistrés psicológico. COVID-19EpidemiologiaFisiopatologiaCardiomiopatia de TakotsuboEstresse emocional. Introduction: Takotsubo syndrome (TTS) is characterized by a temporary left ventricular (LV) systolic dysfunction, usually in the context of acute physical or emotional stress. Thus, the stress mechanism generated by the pandemic and the COVID-19 infection has been related to this syndrome. Objective: To analyze, through a literature review, the relationship between COVID-19 and Takotsubo Syndrome, taking into account the pathophysiological mechanisms involved. Methods: This is a literature review with searches performed in July 2022, using the PubMed database. Results and Discussion: 29 articles were selected, after full evaluation, the main findings show an increase in the incidence of TTS in the general population and in patients with COVID-19. The pathophysiological mechanisms involved include the increase in catecholamines and cortisol, cytokine storm, microvascular dysfunction and the direct action of SARS-COV-2 on cardiomyocytes and endothelium, in addition to the psychological burden resulting from the pandemic. Conclusion: The incidence of stress-induced cardiomyopathy is expected to increase in the general population, driven by the psychosocial consequences of this period. Therefore, it is imperative that clinicians are familiar with the clinical presentation, possible complications, and management of TTS.Introducción: El síndrome de Takotsubo (TTS) se caracteriza por una disfunción sistólica temporal del ventrículo izquierdo (VI), generalmente en el contexto de estrés físico o emocional agudo. Así, el mecanismo de estrés generado por la pandemia y la infección por COVID-19 se ha relacionado con este síndrome. Objetivo: Analizar, a través de una revisión bibliográfica, la relación entre el COVID-19 y el Síndrome de Takotsubo, teniendo en cuenta los mecanismos fisiopatológicos involucrados. Métodos: Esta es una revisión de la literatura con búsquedas realizadas en julio de 2022, utilizando la base de datos PubMed. Resultados y Discusión: Se seleccionaron 29 artículos, luego de una evaluación completa, los principales hallazgos muestran un aumento en la incidencia de STT en la población general y en pacientes con COVID-19. Los mecanismos fisiopatológicos involucrados incluyen el aumento de catecolaminas y cortisol, la tormenta de citocinas, la disfunción microvascular y la acción directa del SARS-COV-2 sobre los cardiomiocitos y el endotelio, además de la carga psicológica derivada de la pandemia. Conclusión: Se espera que la incidencia de miocardiopatía inducida por estrés aumente en la población general, impulsada por las consecuencias psicosociales de este período. Por lo tanto, es imperativo que los médicos estén familiarizados con la presentación clínica, las posibles complicaciones y el manejo del TTS.Introdução: A síndrome de Takotsubo (STT) é caracterizada por uma disfunção sistólica temporária do ventrículo esquerdo (VE), geralmente no contexto de estresse físico ou emocional agudo. Sendo assim, o mecanismo de estresse gerado pela pandemia e pela infecção do COVID-19 tem sido relacionado a essa síndrome. Objetivo: Analisar, por meio de uma revisão de literatura, a relação entre a COVID-19 e a Síndrome de Takotsubo, levando em consideração os mecanismos fisiopatológicos envolvidos. Métodos: Trata-se de uma revisão de literatura com buscas realizadas em julho de 2022, utilizando a base de dados PubMed. Resultados e Discussão: Foram selecionados 29 artigos, após avaliação na íntegra, os principais achados mostram aumento da incidência da STT na população geral e em pacientes com COVID-19. Os mecanismos fisiopatológicos envolvidos incluem o aumento de catecolaminas e cortisol, tempestade de citocinas, disfunção microvascular e a ação direta do SARS-COV-2 nos cardiomiócitos e no endotélio, além da sobrecarga psicológica decorrente da pandemia. Conclusão: Espera-se que a incidência de cardiomiopatia induzida por estresse aumente na população em geral, impulsionada pelas consequências psicossociais desse período. Portanto, é imprescindível que os médicos estejam familiarizados com a apresentação clínica, possíveis complicações e manejo da STT.Research, Society and Development2022-11-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3681010.33448/rsd-v11i14.36810Research, Society and Development; Vol. 11 No. 14; e587111436810Research, Society and Development; Vol. 11 Núm. 14; e587111436810Research, Society and Development; v. 11 n. 14; e5871114368102525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/36810/30694Copyright (c) 2022 Eduarda Santana dos Santos; Úrsula Maria Moreira Costa Burgos; Ana Teresa dos Anjos Nobre; Arthur Oliveira da Cruz; Gabrielle Araújo Oliveira Santana; Lara Lima Canuto; Mariana Flor Rocha Mendonça Melo; Maysa Nogueira de Barros Melohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, Eduarda Santana dos Burgos, Úrsula Maria Moreira CostaNobre, Ana Teresa dos Anjos Cruz, Arthur Oliveira daSantana, Gabrielle Araújo Oliveira Canuto, Lara LimaMelo, Mariana Flor Rocha Mendonça Melo, Maysa Nogueira de Barros 2022-11-08T13:36:27Zoai:ojs.pkp.sfu.ca:article/36810Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:51:13.173242Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Takotsubo syndrome in the context of the COVID-19 pandemic: An integrative review Síndrome de Takotsubo en el contexto de la pandemia de COVID-19: Una revisión integradora Síndrome de Takotsubo no contexto da pandemia de COVID-19: Uma revisão integrativa |
title |
Takotsubo syndrome in the context of the COVID-19 pandemic: An integrative review |
spellingShingle |
Takotsubo syndrome in the context of the COVID-19 pandemic: An integrative review Santos, Eduarda Santana dos Takotsubo Cardiomyopathy COVID-19 Epidemiology Pathophysiology Psychological distress. Cardiomiopatia de Takotsubo COVID-19 Epidemiología Fisiopatología Distrés psicológico. COVID-19 Epidemiologia Fisiopatologia Cardiomiopatia de Takotsubo Estresse emocional. |
title_short |
Takotsubo syndrome in the context of the COVID-19 pandemic: An integrative review |
title_full |
Takotsubo syndrome in the context of the COVID-19 pandemic: An integrative review |
title_fullStr |
Takotsubo syndrome in the context of the COVID-19 pandemic: An integrative review |
title_full_unstemmed |
Takotsubo syndrome in the context of the COVID-19 pandemic: An integrative review |
title_sort |
Takotsubo syndrome in the context of the COVID-19 pandemic: An integrative review |
author |
Santos, Eduarda Santana dos |
author_facet |
Santos, Eduarda Santana dos Burgos, Úrsula Maria Moreira Costa Nobre, Ana Teresa dos Anjos Cruz, Arthur Oliveira da Santana, Gabrielle Araújo Oliveira Canuto, Lara Lima Melo, Mariana Flor Rocha Mendonça Melo, Maysa Nogueira de Barros |
author_role |
author |
author2 |
Burgos, Úrsula Maria Moreira Costa Nobre, Ana Teresa dos Anjos Cruz, Arthur Oliveira da Santana, Gabrielle Araújo Oliveira Canuto, Lara Lima Melo, Mariana Flor Rocha Mendonça Melo, Maysa Nogueira de Barros |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Santos, Eduarda Santana dos Burgos, Úrsula Maria Moreira Costa Nobre, Ana Teresa dos Anjos Cruz, Arthur Oliveira da Santana, Gabrielle Araújo Oliveira Canuto, Lara Lima Melo, Mariana Flor Rocha Mendonça Melo, Maysa Nogueira de Barros |
dc.subject.por.fl_str_mv |
Takotsubo Cardiomyopathy COVID-19 Epidemiology Pathophysiology Psychological distress. Cardiomiopatia de Takotsubo COVID-19 Epidemiología Fisiopatología Distrés psicológico. COVID-19 Epidemiologia Fisiopatologia Cardiomiopatia de Takotsubo Estresse emocional. |
topic |
Takotsubo Cardiomyopathy COVID-19 Epidemiology Pathophysiology Psychological distress. Cardiomiopatia de Takotsubo COVID-19 Epidemiología Fisiopatología Distrés psicológico. COVID-19 Epidemiologia Fisiopatologia Cardiomiopatia de Takotsubo Estresse emocional. |
description |
Introduction: Takotsubo syndrome (TTS) is characterized by a temporary left ventricular (LV) systolic dysfunction, usually in the context of acute physical or emotional stress. Thus, the stress mechanism generated by the pandemic and the COVID-19 infection has been related to this syndrome. Objective: To analyze, through a literature review, the relationship between COVID-19 and Takotsubo Syndrome, taking into account the pathophysiological mechanisms involved. Methods: This is a literature review with searches performed in July 2022, using the PubMed database. Results and Discussion: 29 articles were selected, after full evaluation, the main findings show an increase in the incidence of TTS in the general population and in patients with COVID-19. The pathophysiological mechanisms involved include the increase in catecholamines and cortisol, cytokine storm, microvascular dysfunction and the direct action of SARS-COV-2 on cardiomyocytes and endothelium, in addition to the psychological burden resulting from the pandemic. Conclusion: The incidence of stress-induced cardiomyopathy is expected to increase in the general population, driven by the psychosocial consequences of this period. Therefore, it is imperative that clinicians are familiar with the clinical presentation, possible complications, and management of TTS. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-11-07 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/36810 10.33448/rsd-v11i14.36810 |
url |
https://rsdjournal.org/index.php/rsd/article/view/36810 |
identifier_str_mv |
10.33448/rsd-v11i14.36810 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/36810/30694 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 14; e587111436810 Research, Society and Development; Vol. 11 Núm. 14; e587111436810 Research, Society and Development; v. 11 n. 14; e587111436810 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052727928291328 |