Overview of neonatal sepsis in an Intensive Care Unit: a literature review

Detalhes bibliográficos
Autor(a) principal: Catapani, Emanuelle Brancalion
Data de Publicação: 2023
Outros Autores: Menezes, João Daniel de Souza, Guarnieri, Giovanna Marques, Pereira, Amanda Alves, Sacardo, Yuri, Parro, Maria Cláudia
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/40796
Resumo: Neonatal sepsis is considered a systemic inflammatory response syndrome caused by suspected or confirmed infection, being one of the main causes of neonatal death worldwide and one of the main causes of increased neonatal mortality. In Brazil, on average, 3,000 children die each year from neonatal sepsis, with prematurity being na additional risk factor. Objective: to understand through the literature about sepsis in newborns. Methodology: this is a literature review study, according to pre-established criteria for selection and exclusion of articles. We opted for more recently published articles that answered the guiding question: “What has been disclosed about the development of sepsis in pediatric patients”. Results: Neonatal sepsis can be classified as early (PNS), in which it occurs in the first 48 to 72 hours of life; or late (SNT), which occurs after 72 hours. SNP can be caused by maternal risk factors and/or interactions during childbirth or neonatal, while SNT holds the main risk factors inherent in the newborn. Clinical manifestations are very variable and nonspecific, which makes the diagnosis of neonatal sepsis difficult. Complementary tests are based on collection of blood and cerebrospinal fluid and, in late sepsis, urine culture. Given the diagnosis, treatment is carried out through empirical antibiotic therapy. Conclusion: the detailed and continuous observation of the newborn, its clinical signs and risk factors is fundamental for the morbidity and mortality of neonatal sepsis to be reduced.
id UNIFEI_c6c88542db8210f62565cec15c50e5c1
oai_identifier_str oai:ojs.pkp.sfu.ca:article/40796
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Overview of neonatal sepsis in an Intensive Care Unit: a literature reviewPanorama general de la sepsis neonatal en una Unidad de Cuidados Intensivos: una revisión de la literaturaPanorama da sepse neonatal em Unidade de Terapia Intensiva: uma revisão integrativaNeonatologiaSepseEnfermagem.NeonatologíaSepticemiaEnfermería.NeonatologySepsisNursing.Neonatal sepsis is considered a systemic inflammatory response syndrome caused by suspected or confirmed infection, being one of the main causes of neonatal death worldwide and one of the main causes of increased neonatal mortality. In Brazil, on average, 3,000 children die each year from neonatal sepsis, with prematurity being na additional risk factor. Objective: to understand through the literature about sepsis in newborns. Methodology: this is a literature review study, according to pre-established criteria for selection and exclusion of articles. We opted for more recently published articles that answered the guiding question: “What has been disclosed about the development of sepsis in pediatric patients”. Results: Neonatal sepsis can be classified as early (PNS), in which it occurs in the first 48 to 72 hours of life; or late (SNT), which occurs after 72 hours. SNP can be caused by maternal risk factors and/or interactions during childbirth or neonatal, while SNT holds the main risk factors inherent in the newborn. Clinical manifestations are very variable and nonspecific, which makes the diagnosis of neonatal sepsis difficult. Complementary tests are based on collection of blood and cerebrospinal fluid and, in late sepsis, urine culture. Given the diagnosis, treatment is carried out through empirical antibiotic therapy. Conclusion: the detailed and continuous observation of the newborn, its clinical signs and risk factors is fundamental for the morbidity and mortality of neonatal sepsis to be reduced.La sepsis neonatal se considera un síndrome de respuesta inflamatoria sistémica causado por una infección sospechada o confirmada, siendo una de las principales causas de muerte neonatal a nivel mundial y una de las principales causas del aumento de la mortalidad neonatal. En Brasil, en promedio, 3.000 niños mueren cada año por sepsis neonatal, siendo la prematuridad un factor de riesgo adicional. Objetivo: comprender a través de la literatura acerca de la sepsis en recién nacidos. Metodología: se trata de un estudio de revisión bibliográfica, según criterios preestablecidos de selección y exclusión de artículos. Optamos por artículos publicados más recientemente que respondieran a la pregunta guía: “¿Qué se ha divulgado sobre el desarrollo de sepsis en pacientes pediátricos?”. Resultados: La sepsis neonatal se puede clasificar en temprana (SNP), en la que se presenta en las primeras 48 a 72 horas de vida; o tarde (SNT), que ocurre después de 72 horas. El SNP puede ser causado por factores de riesgo maternos y/o interacciones durante el parto o neonatal, mientras que el SNT contiene los principales factores de riesgo inherentes al recién nacido. Las manifestaciones clínicas son muy variables e inespecíficas, lo que dificulta el diagnóstico de sepsis neonatal. Las pruebas complementarias se basan en la extracción de sangre y líquido cefalorraquídeo y, en la sepsis tardía, el cultivo de orina. Dado el diagnóstico, el tratamiento se realiza mediante antibioterapia empírica. Conclusión: la observación detallada y continua del recién nacido, sus signos clínicos y factores de riesgo es fundamental para que se reduzca la morbimortalidad de la sepsis neonatal.A sepse neonatal é considerada uma síndrome de resposta inflamatória sistêmica causada por infecção suspeita ou confirmada, sendo uma das principais causas de morte neonatal em todo o mundo e uma das principais causas de aumento da mortalidade neonatal. No Brasil, em média, 3.000 crianças morrem a cada ano por sepse neonatal, sendo a prematuridade um fator de risco adicional. Objetivo: compreender através da literatura sobre a sepse em recém-nascidos. Metodologia: trata-se de um estudo de revisão de literatura, segundo critérios pré-estabelecidos de seleção e exclusão de artigos. Optou-se por artigos mais recentemente publicados que respondessem a pergunta norteadora: “O que vem sendo divulgado sobre o desenvolvimento de sepse em paciente pediátricos”. Resultados: A sepse neonatal pode ser classificada em precoce (SNP), em que ocorre nas primeiras 48 a 72 horas de vida; ou em tardia (SNT), que ocorre após as 72 horas. A SNP pode ser causada por fatores de risco materno e/ou interações durante o parto ou neonatal, enquanto que a SNT detém os fatores de risco principais inerentes ao recém-nascido. As manifestações clínicas são muito variáveis e inespecíficas, o que dificulta o diagnóstico de sepse neonatal. Os exames complementares baseiam-se na coleta de hemocultura e líquor e, na sepse tardia, a urocultura. Dado o diagnóstico, o tratamento é realizado por meio da antibioticoterapia empírica. Conclusão: a observação minuciosa e contínua do recém-nascido, dos seus sinais clínicos e fatores de risco é fundamental para que a morbimortalidade de sepse neonatal seja reduzida.Research, Society and Development2023-05-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4079610.33448/rsd-v12i5.40796Research, Society and Development; Vol. 12 No. 5; e11212540796Research, Society and Development; Vol. 12 Núm. 5; e11212540796Research, Society and Development; v. 12 n. 5; e112125407962525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/40796/33752Copyright (c) 2023 Emanuelle Brancalion Catapani; João Daniel de Souza Menezes; Giovanna Marques Guarnieri; Amanda Alves Pereira; Yuri Sacardo; Maria Cláudia Parrohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCatapani, Emanuelle BrancalionMenezes, João Daniel de SouzaGuarnieri, Giovanna MarquesPereira, Amanda AlvesSacardo, YuriParro, Maria Cláudia 2023-05-30T13:24:21Zoai:ojs.pkp.sfu.ca:article/40796Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-05-30T13:24:21Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Overview of neonatal sepsis in an Intensive Care Unit: a literature review
Panorama general de la sepsis neonatal en una Unidad de Cuidados Intensivos: una revisión de la literatura
Panorama da sepse neonatal em Unidade de Terapia Intensiva: uma revisão integrativa
title Overview of neonatal sepsis in an Intensive Care Unit: a literature review
spellingShingle Overview of neonatal sepsis in an Intensive Care Unit: a literature review
Catapani, Emanuelle Brancalion
Neonatologia
Sepse
Enfermagem.
Neonatología
Septicemia
Enfermería.
Neonatology
Sepsis
Nursing.
title_short Overview of neonatal sepsis in an Intensive Care Unit: a literature review
title_full Overview of neonatal sepsis in an Intensive Care Unit: a literature review
title_fullStr Overview of neonatal sepsis in an Intensive Care Unit: a literature review
title_full_unstemmed Overview of neonatal sepsis in an Intensive Care Unit: a literature review
title_sort Overview of neonatal sepsis in an Intensive Care Unit: a literature review
author Catapani, Emanuelle Brancalion
author_facet Catapani, Emanuelle Brancalion
Menezes, João Daniel de Souza
Guarnieri, Giovanna Marques
Pereira, Amanda Alves
Sacardo, Yuri
Parro, Maria Cláudia
author_role author
author2 Menezes, João Daniel de Souza
Guarnieri, Giovanna Marques
Pereira, Amanda Alves
Sacardo, Yuri
Parro, Maria Cláudia
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Catapani, Emanuelle Brancalion
Menezes, João Daniel de Souza
Guarnieri, Giovanna Marques
Pereira, Amanda Alves
Sacardo, Yuri
Parro, Maria Cláudia
dc.subject.por.fl_str_mv Neonatologia
Sepse
Enfermagem.
Neonatología
Septicemia
Enfermería.
Neonatology
Sepsis
Nursing.
topic Neonatologia
Sepse
Enfermagem.
Neonatología
Septicemia
Enfermería.
Neonatology
Sepsis
Nursing.
description Neonatal sepsis is considered a systemic inflammatory response syndrome caused by suspected or confirmed infection, being one of the main causes of neonatal death worldwide and one of the main causes of increased neonatal mortality. In Brazil, on average, 3,000 children die each year from neonatal sepsis, with prematurity being na additional risk factor. Objective: to understand through the literature about sepsis in newborns. Methodology: this is a literature review study, according to pre-established criteria for selection and exclusion of articles. We opted for more recently published articles that answered the guiding question: “What has been disclosed about the development of sepsis in pediatric patients”. Results: Neonatal sepsis can be classified as early (PNS), in which it occurs in the first 48 to 72 hours of life; or late (SNT), which occurs after 72 hours. SNP can be caused by maternal risk factors and/or interactions during childbirth or neonatal, while SNT holds the main risk factors inherent in the newborn. Clinical manifestations are very variable and nonspecific, which makes the diagnosis of neonatal sepsis difficult. Complementary tests are based on collection of blood and cerebrospinal fluid and, in late sepsis, urine culture. Given the diagnosis, treatment is carried out through empirical antibiotic therapy. Conclusion: the detailed and continuous observation of the newborn, its clinical signs and risk factors is fundamental for the morbidity and mortality of neonatal sepsis to be reduced.
publishDate 2023
dc.date.none.fl_str_mv 2023-05-10
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/40796
10.33448/rsd-v12i5.40796
url https://rsdjournal.org/index.php/rsd/article/view/40796
identifier_str_mv 10.33448/rsd-v12i5.40796
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/40796/33752
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 12 No. 5; e11212540796
Research, Society and Development; Vol. 12 Núm. 5; e11212540796
Research, Society and Development; v. 12 n. 5; e11212540796
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052620618072064