Use of xenograft for tissue repair in the treatment of burns: integrative literature review

• Autor(a) principal: Silva, Eduardo Brito da
• Data de Publicação: 2021
• Outros Autores: Silva, Kaio Germano Sousa da, Coêlho , Luana Pereira Ibiapina, da Silva, Wenderson Costa, Aguiar, Leiliane Barbosa de, Silva, Felipe Azevedo da, Silva , Amanda Kauany Pereira da, Marques, Victória Ribeiro de Sousa, Coelho, Lara Beatriz de Sousa, Melo, Rafael Fernandes de, Rocha, Danielle Carvalho, Chaves, Rondinelle dos Santos, Mesquita, Eudilene da Silva, Coêlho , Bruna Rafaelle Pereira Ibiapina, Leão, George do Carmo, Santos , Jesica Cristina Lira dos, Coelho , Isadora Sayonara Ferreira, Oliveira , Milka Esthefanni dos Santos Passos, Ferreira, Geovanna Clara Cunha Lima, Santos , Thalita Cristina Oliveira, Nascimento, Ianca Sabrina Silva, Santos, Sara Tereza Lisboa dos, Viana, Jeslaine da Silva Alves, Silva, Wanderson de Almeida, Silva, Laianny Luize Lima e
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/18560
• topic: Burns; Heterografts; Wound healing.; Quemaduras; Xenoinjertos; Cicatrización de heridas.; Queimaduras; Xenoenxertos; Cicatrização.

Biological tissues of animal origin, such as pig skin, frog skin, bovine pericardium and pig intestinal submucosa have been used in bioocclusive dressings (xenotransplantation) for burns. The present study aimed to analyze the use of xenograft therapy in the treatment of burns. This is an integrative literature review, in which the following clinical question was formulated: “What is the scientific evidence on the use of xenograft therapy in tissue repair in burn victims?”. PubMed, Bireme and CINAHL databases were consulted. Studies available in their entirety, published from 2016 to 2021, in Portuguese, Spanish and English, were used. Eight studies were included in this review. The studies addressed the characteristics of the use of xenograft as a biological dressing in the therapy of burn patients, such as gender, type of burn, degree of burn, percentage of affected area, type of biological dressing, indication, intervention time and evolution of cases. The results conclude that the use of xenotransplantation has been shown to be effective in reducing pain, reducing hospital stays, faster re-epithelialization, less dressing changes, lower cost-effectiveness, and fewer infections. The study allowed an evaluation of the treatment of burns through heterologous dressing therapy, concluding that it is effective, in addition, it was concluded that the Nile tilapia skin dressing had statistically more significant results when compared to all interventions, including with porcine biological dressing.