Analysis of the pharmacological activities of Handroanthus serratifolius (Vahl) S.Grose
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/22891 |
Resumo: | Handroanthus serratifolius (Vahl) S.Grose, (syn. Handroanthus albus; syn. Tabebuia serratifolia), popularly known as yellow-ipê, belongs to the Bignoniaceae family. Plants of this family have several pharmacological activities described in the literature, which occur due to the presence of secondary metabolites, such as lapachol, which induces oxidative stress in cells and can be effective against obligate intracellular parasites and cancer cells. The aim of the article was to analyze the pharmacological properties present in chemical compounds isolated from different parts of H. serratifolius (Vahl) S.Grose, (syn. H. albus; syn. T. serratifolia). The study is an integrative literature review, carried out in the databases Science Direct, Google Scholar, Embase, MEDLINE via PubMed, Web of Science and the Virtual Health Library (VHL), based on works published in the last six years, in Portuguese and English, that have fully addressed the topic under investigation. It was observed in the analyzed studies that the species of yellow ipe have antibacterial, antinociceptive, antifungal, antiinflammatory, antiparasitic, cytotoxic, antileishmanial and antiplasmoid activities, and that these activities can be found in leaf and stem extracts. Furthermore, lapachol has been shown to be responsible for some of these pharmacological properties. Therefore, it can be concluded that Handroanthus serratifolius is a potential source for research and development of new substances with different pharmacological applicability. |
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Analysis of the pharmacological activities of Handroanthus serratifolius (Vahl) S.GroseAnálisis de las actividades farmacológicas de Handroanthus serratifolius (Vahl) S.GroseAnálise das atividades farmacológicas da Handroanthus serratifolius (Vahl) S.GroseHandroanthus serratifolius (Vahl) S.GroseHandroanthus albusTabebuia serratifoliaPharmacological activityLapachol.Handroanthus serratifolius (Vahl) S.GroseHandroanthus albusTabebuia serratifoliaActividad farmacológicaLapachol.Handroanthus serratifolius (Vahl) S.GroseHandroanthus albusTabebuia serratifoliaAtividade farmacológicaLapachol.Handroanthus serratifolius (Vahl) S.Grose, (syn. Handroanthus albus; syn. Tabebuia serratifolia), popularly known as yellow-ipê, belongs to the Bignoniaceae family. Plants of this family have several pharmacological activities described in the literature, which occur due to the presence of secondary metabolites, such as lapachol, which induces oxidative stress in cells and can be effective against obligate intracellular parasites and cancer cells. The aim of the article was to analyze the pharmacological properties present in chemical compounds isolated from different parts of H. serratifolius (Vahl) S.Grose, (syn. H. albus; syn. T. serratifolia). The study is an integrative literature review, carried out in the databases Science Direct, Google Scholar, Embase, MEDLINE via PubMed, Web of Science and the Virtual Health Library (VHL), based on works published in the last six years, in Portuguese and English, that have fully addressed the topic under investigation. It was observed in the analyzed studies that the species of yellow ipe have antibacterial, antinociceptive, antifungal, antiinflammatory, antiparasitic, cytotoxic, antileishmanial and antiplasmoid activities, and that these activities can be found in leaf and stem extracts. Furthermore, lapachol has been shown to be responsible for some of these pharmacological properties. Therefore, it can be concluded that Handroanthus serratifolius is a potential source for research and development of new substances with different pharmacological applicability.Handroanthus serratifolius (Vahl) S. Grose, (sin. Handroanthus albus; sin. Tabebuia serratifolia), planta de la familia Bignoniaceae, conocida popularmente como yellow-ipê. Las plantas de la familia Bignoniaceae, tienen varias actividades farmacológicas descritas en la literatura. Estas propiedades se deben a la presencia de metabolitos secundarios, como el lapachol, que induce estrés oxidativo en las células y puede ser eficaz contra parásitos intracelulares obligados y células cancerosas. Así, las plantas emergen como fuentes importantes en la investigación y desarrollo de nuevas alternativas terapéuticas o en la mejora de tratamientos existentes. Así, el objetivo del artículo fue analizar las propiedades farmacológicas presentes en compuestos químicos aislados de diferentes partes de H. serratifolius (Vahl) S.Grose, (sin. H. albus; sin. T. serratifolia). El estudio es una revisión integradora de la literatura, realizada en las bases de datos Science Direct, Google Scholar, Embase, MEDLINE vía PubMed, Web of Science y la Virtual Health Library (VHL), a partir de trabajos publicados en los últimos seis años, en portugués e inglés, que han abordado en su totalidad el tema investigado. En los estudios analizados se observó que las especies de ipe amarillo tienen actividades antibacterianas, antinociceptivas, antifúngicas, antiinflamatorias, antiparasitarias, citotóxicas, antileishmaniales y antiplasmoides, y que estas actividades se pueden encontrar en extractos de hojas y tallos. Además, se ha demostrado que el lapachol es responsable de algunas de estas propiedades farmacológicas. Por tanto, se puede concluir que Handroanthus serratifolius es una fuente potencial de investigación y desarrollo de nuevas sustancias con diferente aplicabilidad farmacológica.Handroanthus serratifolius (Vahl) S.Grose, (sin. Handroanthus albus; sin. Tabebuia serratifolia), conhecida popularmente como ipê-amarelo, pertence à família Bignoniaceae. Plantas dessa família, possuem diversas atividades farmacológicas descritas na literatura, as quais ocorrem devido à presença de metabólitos secundários como, por exemplo, o lapachol, que induz o estresse oxidativo em células e pode ser eficaz contra parasitas intracelulares obrigatórios e células de câncer. O objetivo do artigo foi analisar as propriedades farmacológicas presentes nos compostos químicos isolados de diferentes partes da H. serratifolius (Vahl) S.Grose, (sin. H. albus; sin. T. serratifolia). O estudo trata-se de uma revisão de literatura do tipo integrativa, realizada nas bases de dados Science Direct, Google Scholar, Embase, MEDLINE via PubMed, Web of Science e na Biblioteca Virtual de Saúde (BVS), a partir de trabalhos publicados nos últimos seis anos, nos idiomas português e inglês, que tenham abordado na íntegra o tema em pesquisa. Observou-se nos estudos analisados que as espécies de ipê amarelo possuem atividades antibacteriana, antinociceptiva, antifúngica, antinflámatória, antiparasitária, citotóxica, antileishmanicida, e que essas atividades podem ser encontradas em extratos de folhas e no caule. Além disso, o lapachol mostrou-se responsável por algumas dessas propriedades farmacológicas. Portanto, pode-se concluir que a Handroanthus serratifolius é uma fonte potencial para pesquisas e desenvolvimento de novas substâncias com diferentes aplicabilidades farmacológicas.Research, Society and Development2022-01-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2289110.33448/rsd-v11i2.22891Research, Society and Development; Vol. 11 No. 2; e5611222891Research, Society and Development; Vol. 11 Núm. 2; e5611222891Research, Society and Development; v. 11 n. 2; e56112228912525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/22891/22299Copyright (c) 2022 Fernanda Arias de Almeida Macêdo; Mayara Ladeira Coêlho; Manoela Cavalcante Ribeiro; Elcio Daniel Sousa Barros; João Paulo da Silva Gomes; Ceres Lima Batista; Layana Karine Farias Lima; Renato Pinto de Sousahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMacêdo, Fernanda Arias de Almeida Coêlho, Mayara Ladeira Ribeiro, Manoela Cavalcante Barros, Elcio Daniel Sousa Gomes, João Paulo da Silva Batista, Ceres Lima Lima, Layana Karine Farias Sousa, Renato Pinto de 2022-02-07T01:42:50Zoai:ojs.pkp.sfu.ca:article/22891Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:41:55.480800Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Analysis of the pharmacological activities of Handroanthus serratifolius (Vahl) S.Grose Análisis de las actividades farmacológicas de Handroanthus serratifolius (Vahl) S.Grose Análise das atividades farmacológicas da Handroanthus serratifolius (Vahl) S.Grose |
title |
Analysis of the pharmacological activities of Handroanthus serratifolius (Vahl) S.Grose |
spellingShingle |
Analysis of the pharmacological activities of Handroanthus serratifolius (Vahl) S.Grose Macêdo, Fernanda Arias de Almeida Handroanthus serratifolius (Vahl) S.Grose Handroanthus albus Tabebuia serratifolia Pharmacological activity Lapachol. Handroanthus serratifolius (Vahl) S.Grose Handroanthus albus Tabebuia serratifolia Actividad farmacológica Lapachol. Handroanthus serratifolius (Vahl) S.Grose Handroanthus albus Tabebuia serratifolia Atividade farmacológica Lapachol. |
title_short |
Analysis of the pharmacological activities of Handroanthus serratifolius (Vahl) S.Grose |
title_full |
Analysis of the pharmacological activities of Handroanthus serratifolius (Vahl) S.Grose |
title_fullStr |
Analysis of the pharmacological activities of Handroanthus serratifolius (Vahl) S.Grose |
title_full_unstemmed |
Analysis of the pharmacological activities of Handroanthus serratifolius (Vahl) S.Grose |
title_sort |
Analysis of the pharmacological activities of Handroanthus serratifolius (Vahl) S.Grose |
author |
Macêdo, Fernanda Arias de Almeida |
author_facet |
Macêdo, Fernanda Arias de Almeida Coêlho, Mayara Ladeira Ribeiro, Manoela Cavalcante Barros, Elcio Daniel Sousa Gomes, João Paulo da Silva Batista, Ceres Lima Lima, Layana Karine Farias Sousa, Renato Pinto de |
author_role |
author |
author2 |
Coêlho, Mayara Ladeira Ribeiro, Manoela Cavalcante Barros, Elcio Daniel Sousa Gomes, João Paulo da Silva Batista, Ceres Lima Lima, Layana Karine Farias Sousa, Renato Pinto de |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Macêdo, Fernanda Arias de Almeida Coêlho, Mayara Ladeira Ribeiro, Manoela Cavalcante Barros, Elcio Daniel Sousa Gomes, João Paulo da Silva Batista, Ceres Lima Lima, Layana Karine Farias Sousa, Renato Pinto de |
dc.subject.por.fl_str_mv |
Handroanthus serratifolius (Vahl) S.Grose Handroanthus albus Tabebuia serratifolia Pharmacological activity Lapachol. Handroanthus serratifolius (Vahl) S.Grose Handroanthus albus Tabebuia serratifolia Actividad farmacológica Lapachol. Handroanthus serratifolius (Vahl) S.Grose Handroanthus albus Tabebuia serratifolia Atividade farmacológica Lapachol. |
topic |
Handroanthus serratifolius (Vahl) S.Grose Handroanthus albus Tabebuia serratifolia Pharmacological activity Lapachol. Handroanthus serratifolius (Vahl) S.Grose Handroanthus albus Tabebuia serratifolia Actividad farmacológica Lapachol. Handroanthus serratifolius (Vahl) S.Grose Handroanthus albus Tabebuia serratifolia Atividade farmacológica Lapachol. |
description |
Handroanthus serratifolius (Vahl) S.Grose, (syn. Handroanthus albus; syn. Tabebuia serratifolia), popularly known as yellow-ipê, belongs to the Bignoniaceae family. Plants of this family have several pharmacological activities described in the literature, which occur due to the presence of secondary metabolites, such as lapachol, which induces oxidative stress in cells and can be effective against obligate intracellular parasites and cancer cells. The aim of the article was to analyze the pharmacological properties present in chemical compounds isolated from different parts of H. serratifolius (Vahl) S.Grose, (syn. H. albus; syn. T. serratifolia). The study is an integrative literature review, carried out in the databases Science Direct, Google Scholar, Embase, MEDLINE via PubMed, Web of Science and the Virtual Health Library (VHL), based on works published in the last six years, in Portuguese and English, that have fully addressed the topic under investigation. It was observed in the analyzed studies that the species of yellow ipe have antibacterial, antinociceptive, antifungal, antiinflammatory, antiparasitic, cytotoxic, antileishmanial and antiplasmoid activities, and that these activities can be found in leaf and stem extracts. Furthermore, lapachol has been shown to be responsible for some of these pharmacological properties. Therefore, it can be concluded that Handroanthus serratifolius is a potential source for research and development of new substances with different pharmacological applicability. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/22891 10.33448/rsd-v11i2.22891 |
url |
https://rsdjournal.org/index.php/rsd/article/view/22891 |
identifier_str_mv |
10.33448/rsd-v11i2.22891 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/22891/22299 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
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Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 2; e5611222891 Research, Society and Development; Vol. 11 Núm. 2; e5611222891 Research, Society and Development; v. 11 n. 2; e5611222891 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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