Idiopathic intracranial hypertension in children and adolescents in southern Brazil
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
DOI: | 10.33448/rsd-v12i6.42419 |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/42419 |
Resumo: | Introduction: Idiopathic intracranial hypertension (IIH) is a syndrome characterized by signs and symptoms of elevated intracranial pressure without the identification of tumor or ventriculomegaly. The aim of this study is to evaluate the epidemiological profile of children diagnosed with IIH in southern Brazil. Methods: This is a retrospective study, through the analysis of medical records and complementary exams. The medical records of patients diagnosed with IIH from January 2012 to September 2022 were evaluated. Results: Data from 33 children were analyzed and the mean age at diagnosis was 9 years, 66.7% of whom were female. In patients less than 8 years of age, the mean weight Z-score was -0.32 (SD :1.88). Of the analyzed patients, 66.7% had symptoms for up to one month, 93.3% had primary IIH and 86.7% had headache as the first symptom. Regarding treatment, 90.0% responded to monotherapy and 13.3% required surgical intervention. There was a higher risk of surgery in patients who had higher cerebrospinal fluid opening pressure at diagnosis (p=0.029). Visual sequelae at hospital discharge were observed in 47.1% of patients. Conclusion: Clinical signs and symptoms can be variable in pediatrics, requiring additional tests. A higher prevalence of IIH was observed in female adolescents. There is an increase in incidence over time, which reinforces the care and attention for this condition in pediatrics. |
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Idiopathic intracranial hypertension in children and adolescents in southern BrazilHipertensión intracanal idiopática en niños y adolescentes del sur de BrasilHipertensão intracraniana idiopática em crianças e adolescentes no sul do BrasilPseudotumorHipertensão intracraniana idiopáticaPapiledemaPediatria.PseudotumorPapiledemaHipertensión intracraneal idiopáticaPediatría.PseudotumorIdiopathic intracranial hypertensionPapilledemaPediatrics.Introduction: Idiopathic intracranial hypertension (IIH) is a syndrome characterized by signs and symptoms of elevated intracranial pressure without the identification of tumor or ventriculomegaly. The aim of this study is to evaluate the epidemiological profile of children diagnosed with IIH in southern Brazil. Methods: This is a retrospective study, through the analysis of medical records and complementary exams. The medical records of patients diagnosed with IIH from January 2012 to September 2022 were evaluated. Results: Data from 33 children were analyzed and the mean age at diagnosis was 9 years, 66.7% of whom were female. In patients less than 8 years of age, the mean weight Z-score was -0.32 (SD :1.88). Of the analyzed patients, 66.7% had symptoms for up to one month, 93.3% had primary IIH and 86.7% had headache as the first symptom. Regarding treatment, 90.0% responded to monotherapy and 13.3% required surgical intervention. There was a higher risk of surgery in patients who had higher cerebrospinal fluid opening pressure at diagnosis (p=0.029). Visual sequelae at hospital discharge were observed in 47.1% of patients. Conclusion: Clinical signs and symptoms can be variable in pediatrics, requiring additional tests. A higher prevalence of IIH was observed in female adolescents. There is an increase in incidence over time, which reinforces the care and attention for this condition in pediatrics. Introducción: La hipertensión intracraneal idiopática (HII) es un síndrome caracterizado por signos y síntomas de presión intracraneal elevada sin identificación de tumor o ventriculomegalia. El objetivo de este estudio es evaluar el perfil epidemiológico de los niños diagnosticados con HII en el sur de Brasil. Métodos: Este es un estudio retrospectivo, a través del análisis de historias clínicas y exámenes complementarios. Se evaluaron las historias clínicas de los pacientes diagnosticados con HII desde enero de 2012 hasta septiembre de 2022. Resultados: Se analizaron los datos de 33 niños y la edad media al diagnóstico fue de 9 años, de los cuales el 66,7% eran mujeres. En pacientes menores de 8 años, el Z-score de peso medio fue de -0,32 (DE: 1,88). De los pacientes analizados, el 66,7% presentaba síntomas hasta un mes, el 93,3% presentaba HII primaria y el 86,7% presentaba cefalea como primer síntoma. En cuanto al tratamiento, el 90,0% respondió a la monoterapia y el 13,3% requirió intervención quirúrgica. Hubo un mayor riesgo de cirugía en los pacientes que tenían una mayor presión de apertura del líquido cefalorraquídeo en el momento del diagnóstico (p = 0,029). Se observaron secuelas visuales al alta hospitalaria en el 47,1% de los pacientes. Conclusión: Los signos y síntomas clínicos pueden ser variables en pediatría, requiriendo exámenes adicionales. Se observó una mayor prevalencia de HII en mujeres adolescentes. Hay un aumento de la incidencia a lo largo del tiempo, lo que refuerza el cuidado y la atención de esta patología en pediatría.Introdução: A hipertensão intracraniana idiopática (HII) é uma síndrome caracterizada por sinais e sintomas de elevação da pressão intracraniana sem identificação de tumor ou ventriculomegalia. O objetivo deste estudo é avaliar o perfil epidemiológico de crianças com diagnóstico de HII no sul do Brasil. Métodos: Trata-se de um estudo retrospectivo, por meio da análise de prontuários e exames complementares. Foram avaliados os prontuários de pacientes diagnosticados com HII no período de janeiro de 2012 a setembro de 2022. Resultados: Foram analisados dados de 33 crianças e a média de idade ao diagnóstico foi de 9 anos, sendo 66,7% do sexo feminino. Em pacientes com menos de 8 anos de idade, o escore Z de peso médio foi -0,32 (DP:1,88). Dos pacientes analisados, 66,7% apresentavam sintomas por até um mês, 93,3% apresentavam HII primária e 86,7% apresentavam cefaleia como primeiro sintoma. Em relação ao tratamento, 90,0% responderam à monoterapia e 13,3% necessitaram de intervenção cirúrgica. Houve maior risco de cirurgia em pacientes que apresentavam maior pressão de abertura do líquido cefalorraquidiano ao diagnóstico (p=0,029). Sequelas visuais na alta hospitalar foram observadas em 47,1% dos pacientes. Conclusão: Os sinais e sintomas clínicos podem ser variáveis em pediatria, necessitando de exames complementares. Maior prevalência de HII foi observada em adolescentes do sexo feminino. Há aumento da incidência ao longo do tempo, o que reforça o cuidado e a atenção com essa condição na pediatria.Research, Society and Development2023-07-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4241910.33448/rsd-v12i6.42419Research, Society and Development; Vol. 12 No. 6; e29512642419Research, Society and Development; Vol. 12 Núm. 6; e29512642419Research, Society and Development; v. 12 n. 6; e295126424192525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/42419/34273Copyright (c) 2023 Amanda Lopes Pereira Reto; Caroline Mensor Folchini; Simone Carreiro Vieira Karuta; Solena Ziemer Kusma Fidalski; Daniel Almeida do Vallehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessReto, Amanda Lopes Pereira Folchini, Caroline Mensor Karuta, Simone Carreiro Vieira Fidalski, Solena Ziemer Kusma Valle, Daniel Almeida do 2023-07-06T11:16:27Zoai:ojs.pkp.sfu.ca:article/42419Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-07-06T11:16:27Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Idiopathic intracranial hypertension in children and adolescents in southern Brazil Hipertensión intracanal idiopática en niños y adolescentes del sur de Brasil Hipertensão intracraniana idiopática em crianças e adolescentes no sul do Brasil |
title |
Idiopathic intracranial hypertension in children and adolescents in southern Brazil |
spellingShingle |
Idiopathic intracranial hypertension in children and adolescents in southern Brazil Idiopathic intracranial hypertension in children and adolescents in southern Brazil Reto, Amanda Lopes Pereira Pseudotumor Hipertensão intracraniana idiopática Papiledema Pediatria. Pseudotumor Papiledema Hipertensión intracraneal idiopática Pediatría. Pseudotumor Idiopathic intracranial hypertension Papilledema Pediatrics. Reto, Amanda Lopes Pereira Pseudotumor Hipertensão intracraniana idiopática Papiledema Pediatria. Pseudotumor Papiledema Hipertensión intracraneal idiopática Pediatría. Pseudotumor Idiopathic intracranial hypertension Papilledema Pediatrics. |
title_short |
Idiopathic intracranial hypertension in children and adolescents in southern Brazil |
title_full |
Idiopathic intracranial hypertension in children and adolescents in southern Brazil |
title_fullStr |
Idiopathic intracranial hypertension in children and adolescents in southern Brazil Idiopathic intracranial hypertension in children and adolescents in southern Brazil |
title_full_unstemmed |
Idiopathic intracranial hypertension in children and adolescents in southern Brazil Idiopathic intracranial hypertension in children and adolescents in southern Brazil |
title_sort |
Idiopathic intracranial hypertension in children and adolescents in southern Brazil |
author |
Reto, Amanda Lopes Pereira |
author_facet |
Reto, Amanda Lopes Pereira Reto, Amanda Lopes Pereira Folchini, Caroline Mensor Karuta, Simone Carreiro Vieira Fidalski, Solena Ziemer Kusma Valle, Daniel Almeida do Folchini, Caroline Mensor Karuta, Simone Carreiro Vieira Fidalski, Solena Ziemer Kusma Valle, Daniel Almeida do |
author_role |
author |
author2 |
Folchini, Caroline Mensor Karuta, Simone Carreiro Vieira Fidalski, Solena Ziemer Kusma Valle, Daniel Almeida do |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Reto, Amanda Lopes Pereira Folchini, Caroline Mensor Karuta, Simone Carreiro Vieira Fidalski, Solena Ziemer Kusma Valle, Daniel Almeida do |
dc.subject.por.fl_str_mv |
Pseudotumor Hipertensão intracraniana idiopática Papiledema Pediatria. Pseudotumor Papiledema Hipertensión intracraneal idiopática Pediatría. Pseudotumor Idiopathic intracranial hypertension Papilledema Pediatrics. |
topic |
Pseudotumor Hipertensão intracraniana idiopática Papiledema Pediatria. Pseudotumor Papiledema Hipertensión intracraneal idiopática Pediatría. Pseudotumor Idiopathic intracranial hypertension Papilledema Pediatrics. |
description |
Introduction: Idiopathic intracranial hypertension (IIH) is a syndrome characterized by signs and symptoms of elevated intracranial pressure without the identification of tumor or ventriculomegaly. The aim of this study is to evaluate the epidemiological profile of children diagnosed with IIH in southern Brazil. Methods: This is a retrospective study, through the analysis of medical records and complementary exams. The medical records of patients diagnosed with IIH from January 2012 to September 2022 were evaluated. Results: Data from 33 children were analyzed and the mean age at diagnosis was 9 years, 66.7% of whom were female. In patients less than 8 years of age, the mean weight Z-score was -0.32 (SD :1.88). Of the analyzed patients, 66.7% had symptoms for up to one month, 93.3% had primary IIH and 86.7% had headache as the first symptom. Regarding treatment, 90.0% responded to monotherapy and 13.3% required surgical intervention. There was a higher risk of surgery in patients who had higher cerebrospinal fluid opening pressure at diagnosis (p=0.029). Visual sequelae at hospital discharge were observed in 47.1% of patients. Conclusion: Clinical signs and symptoms can be variable in pediatrics, requiring additional tests. A higher prevalence of IIH was observed in female adolescents. There is an increase in incidence over time, which reinforces the care and attention for this condition in pediatrics. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-04 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/42419 10.33448/rsd-v12i6.42419 |
url |
https://rsdjournal.org/index.php/rsd/article/view/42419 |
identifier_str_mv |
10.33448/rsd-v12i6.42419 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/42419/34273 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 12 No. 6; e29512642419 Research, Society and Development; Vol. 12 Núm. 6; e29512642419 Research, Society and Development; v. 12 n. 6; e29512642419 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1822182214933151744 |
dc.identifier.doi.none.fl_str_mv |
10.33448/rsd-v12i6.42419 |