Idiopathic intracranial hypertension in children and adolescents in southern Brazil

Detalhes bibliográficos
Autor(a) principal: Reto, Amanda Lopes Pereira
Data de Publicação: 2023
Outros Autores: Folchini, Caroline Mensor, Karuta, Simone Carreiro Vieira, Fidalski, Solena Ziemer Kusma, Valle, Daniel Almeida do
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/42419
Resumo: Introduction: Idiopathic intracranial hypertension (IIH) is a syndrome characterized by signs and symptoms of elevated intracranial pressure without the identification of tumor or ventriculomegaly. The aim of this study is to evaluate the epidemiological profile of children diagnosed with IIH in southern Brazil. Methods: This is a retrospective study, through the analysis of medical records and complementary exams. The medical records of patients diagnosed with IIH from January 2012 to September 2022 were evaluated. Results: Data from 33 children were analyzed and the mean age at diagnosis was 9 years, 66.7% of whom were female. In patients less than 8 years of age, the mean weight Z-score was -0.32 (SD :1.88). Of the analyzed patients, 66.7% had symptoms for up to one month, 93.3% had primary IIH and 86.7% had headache as the first symptom. Regarding treatment, 90.0% responded to monotherapy and 13.3% required surgical intervention. There was a higher risk of surgery in patients who had higher cerebrospinal fluid opening pressure at diagnosis (p=0.029). Visual sequelae at hospital discharge were observed in 47.1% of patients. Conclusion: Clinical signs and symptoms can be variable in pediatrics, requiring additional tests. A higher prevalence of IIH was observed in female adolescents. There is an increase in incidence over time, which reinforces the care and attention for this condition in pediatrics. 
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spelling Idiopathic intracranial hypertension in children and adolescents in southern BrazilHipertensión intracanal idiopática en niños y adolescentes del sur de BrasilHipertensão intracraniana idiopática em crianças e adolescentes no sul do BrasilPseudotumorHipertensão intracraniana idiopáticaPapiledemaPediatria.PseudotumorPapiledemaHipertensión intracraneal idiopáticaPediatría.PseudotumorIdiopathic intracranial hypertensionPapilledemaPediatrics.Introduction: Idiopathic intracranial hypertension (IIH) is a syndrome characterized by signs and symptoms of elevated intracranial pressure without the identification of tumor or ventriculomegaly. The aim of this study is to evaluate the epidemiological profile of children diagnosed with IIH in southern Brazil. Methods: This is a retrospective study, through the analysis of medical records and complementary exams. The medical records of patients diagnosed with IIH from January 2012 to September 2022 were evaluated. Results: Data from 33 children were analyzed and the mean age at diagnosis was 9 years, 66.7% of whom were female. In patients less than 8 years of age, the mean weight Z-score was -0.32 (SD :1.88). Of the analyzed patients, 66.7% had symptoms for up to one month, 93.3% had primary IIH and 86.7% had headache as the first symptom. Regarding treatment, 90.0% responded to monotherapy and 13.3% required surgical intervention. There was a higher risk of surgery in patients who had higher cerebrospinal fluid opening pressure at diagnosis (p=0.029). Visual sequelae at hospital discharge were observed in 47.1% of patients. Conclusion: Clinical signs and symptoms can be variable in pediatrics, requiring additional tests. A higher prevalence of IIH was observed in female adolescents. There is an increase in incidence over time, which reinforces the care and attention for this condition in pediatrics. Introducción: La hipertensión intracraneal idiopática (HII) es un síndrome caracterizado por signos y síntomas de presión intracraneal elevada sin identificación de tumor o ventriculomegalia. El objetivo de este estudio es evaluar el perfil epidemiológico de los niños diagnosticados con HII en el sur de Brasil. Métodos: Este es un estudio retrospectivo, a través del análisis de historias clínicas y exámenes complementarios. Se evaluaron las historias clínicas de los pacientes diagnosticados con HII desde enero de 2012 hasta septiembre de 2022. Resultados: Se analizaron los datos de 33 niños y la edad media al diagnóstico fue de 9 años, de los cuales el 66,7% eran mujeres. En pacientes menores de 8 años, el Z-score de peso medio fue de -0,32 (DE: 1,88). De los pacientes analizados, el 66,7% presentaba síntomas hasta un mes, el 93,3% presentaba HII primaria y el 86,7% presentaba cefalea como primer síntoma. En cuanto al tratamiento, el 90,0% respondió a la monoterapia y el 13,3% requirió intervención quirúrgica. Hubo un mayor riesgo de cirugía en los pacientes que tenían una mayor presión de apertura del líquido cefalorraquídeo en el momento del diagnóstico (p = 0,029). Se observaron secuelas visuales al alta hospitalaria en el 47,1% de los pacientes. Conclusión: Los signos y síntomas clínicos pueden ser variables en pediatría, requiriendo exámenes adicionales. Se observó una mayor prevalencia de HII en mujeres adolescentes. Hay un aumento de la incidencia a lo largo del tiempo, lo que refuerza el cuidado y la atención de esta patología en pediatría.Introdução: A hipertensão intracraniana idiopática (HII) é uma síndrome caracterizada por sinais e sintomas de elevação da pressão intracraniana sem identificação de tumor ou ventriculomegalia. O objetivo deste estudo é avaliar o perfil epidemiológico de crianças com diagnóstico de HII no sul do Brasil. Métodos: Trata-se de um estudo retrospectivo, por meio da análise de prontuários e exames complementares. Foram avaliados os prontuários de pacientes diagnosticados com HII no período de janeiro de 2012 a setembro de 2022. Resultados: Foram analisados dados de 33 crianças e a média de idade ao diagnóstico foi de 9 anos, sendo 66,7% do sexo feminino. Em pacientes com menos de 8 anos de idade, o escore Z de peso médio foi -0,32 (DP:1,88). Dos pacientes analisados, 66,7% apresentavam sintomas por até um mês, 93,3% apresentavam HII primária e 86,7% apresentavam cefaleia como primeiro sintoma. Em relação ao tratamento, 90,0% responderam à monoterapia e 13,3% necessitaram de intervenção cirúrgica. Houve maior risco de cirurgia em pacientes que apresentavam maior pressão de abertura do líquido cefalorraquidiano ao diagnóstico (p=0,029). Sequelas visuais na alta hospitalar foram observadas em 47,1% dos pacientes. Conclusão: Os sinais e sintomas clínicos podem ser variáveis em pediatria, necessitando de exames complementares. Maior prevalência de HII foi observada em adolescentes do sexo feminino. Há aumento da incidência ao longo do tempo, o que reforça o cuidado e a atenção com essa condição na pediatria.Research, Society and Development2023-07-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4241910.33448/rsd-v12i6.42419Research, Society and Development; Vol. 12 No. 6; e29512642419Research, Society and Development; Vol. 12 Núm. 6; e29512642419Research, Society and Development; v. 12 n. 6; e295126424192525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/42419/34273Copyright (c) 2023 Amanda Lopes Pereira Reto; Caroline Mensor Folchini; Simone Carreiro Vieira Karuta; Solena Ziemer Kusma Fidalski; Daniel Almeida do Vallehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessReto, Amanda Lopes Pereira Folchini, Caroline Mensor Karuta, Simone Carreiro Vieira Fidalski, Solena Ziemer Kusma Valle, Daniel Almeida do 2023-07-06T11:16:27Zoai:ojs.pkp.sfu.ca:article/42419Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-07-06T11:16:27Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Idiopathic intracranial hypertension in children and adolescents in southern Brazil
Hipertensión intracanal idiopática en niños y adolescentes del sur de Brasil
Hipertensão intracraniana idiopática em crianças e adolescentes no sul do Brasil
title Idiopathic intracranial hypertension in children and adolescents in southern Brazil
spellingShingle Idiopathic intracranial hypertension in children and adolescents in southern Brazil
Reto, Amanda Lopes Pereira
Pseudotumor
Hipertensão intracraniana idiopática
Papiledema
Pediatria.
Pseudotumor
Papiledema
Hipertensión intracraneal idiopática
Pediatría.
Pseudotumor
Idiopathic intracranial hypertension
Papilledema
Pediatrics.
title_short Idiopathic intracranial hypertension in children and adolescents in southern Brazil
title_full Idiopathic intracranial hypertension in children and adolescents in southern Brazil
title_fullStr Idiopathic intracranial hypertension in children and adolescents in southern Brazil
title_full_unstemmed Idiopathic intracranial hypertension in children and adolescents in southern Brazil
title_sort Idiopathic intracranial hypertension in children and adolescents in southern Brazil
author Reto, Amanda Lopes Pereira
author_facet Reto, Amanda Lopes Pereira
Folchini, Caroline Mensor
Karuta, Simone Carreiro Vieira
Fidalski, Solena Ziemer Kusma
Valle, Daniel Almeida do
author_role author
author2 Folchini, Caroline Mensor
Karuta, Simone Carreiro Vieira
Fidalski, Solena Ziemer Kusma
Valle, Daniel Almeida do
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Reto, Amanda Lopes Pereira
Folchini, Caroline Mensor
Karuta, Simone Carreiro Vieira
Fidalski, Solena Ziemer Kusma
Valle, Daniel Almeida do
dc.subject.por.fl_str_mv Pseudotumor
Hipertensão intracraniana idiopática
Papiledema
Pediatria.
Pseudotumor
Papiledema
Hipertensión intracraneal idiopática
Pediatría.
Pseudotumor
Idiopathic intracranial hypertension
Papilledema
Pediatrics.
topic Pseudotumor
Hipertensão intracraniana idiopática
Papiledema
Pediatria.
Pseudotumor
Papiledema
Hipertensión intracraneal idiopática
Pediatría.
Pseudotumor
Idiopathic intracranial hypertension
Papilledema
Pediatrics.
description Introduction: Idiopathic intracranial hypertension (IIH) is a syndrome characterized by signs and symptoms of elevated intracranial pressure without the identification of tumor or ventriculomegaly. The aim of this study is to evaluate the epidemiological profile of children diagnosed with IIH in southern Brazil. Methods: This is a retrospective study, through the analysis of medical records and complementary exams. The medical records of patients diagnosed with IIH from January 2012 to September 2022 were evaluated. Results: Data from 33 children were analyzed and the mean age at diagnosis was 9 years, 66.7% of whom were female. In patients less than 8 years of age, the mean weight Z-score was -0.32 (SD :1.88). Of the analyzed patients, 66.7% had symptoms for up to one month, 93.3% had primary IIH and 86.7% had headache as the first symptom. Regarding treatment, 90.0% responded to monotherapy and 13.3% required surgical intervention. There was a higher risk of surgery in patients who had higher cerebrospinal fluid opening pressure at diagnosis (p=0.029). Visual sequelae at hospital discharge were observed in 47.1% of patients. Conclusion: Clinical signs and symptoms can be variable in pediatrics, requiring additional tests. A higher prevalence of IIH was observed in female adolescents. There is an increase in incidence over time, which reinforces the care and attention for this condition in pediatrics. 
publishDate 2023
dc.date.none.fl_str_mv 2023-07-04
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/42419
10.33448/rsd-v12i6.42419
url https://rsdjournal.org/index.php/rsd/article/view/42419
identifier_str_mv 10.33448/rsd-v12i6.42419
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/42419/34273
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 12 No. 6; e29512642419
Research, Society and Development; Vol. 12 Núm. 6; e29512642419
Research, Society and Development; v. 12 n. 6; e29512642419
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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