Considerations on the management of gastroesophageal varices resulting from portal hypertension
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/45302 |
Resumo: | Introduction: Liver cirrhosis is currently the leading cause of portal hypertension, which is a clinical condition with many pathophysiological consequences. In this sense, the approach to gastroesophageal varices resulting from this condition represents a clinical entity of great relevance to the medical scenario. Objectives: The objetive of this study was to evaluate the clinical, epidemiological and pathophysiological aspects of esophageal varices resulting from portal hypertension, building knowledge based on case reports and knowledge based on the literature. Materials and Methods: This is an integrative literature review on the general clinical characteristics of esophageal varices. The PICO strategy was used to develop the guiding question. In addition, the descriptors "Esophageal Varices"; "Portal Hypertension"; "Propaedeutics" were cross-referenced in the National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (SCIELO), Ebscohost, Google Scholar and Virtual Health Library (VHL) databases. Results and Discussion: A significant proportion of the articles showed that variceal upper gastrointestinal bleeding results from the alterations caused by portal hypertension and that it must be managed incisively in order to improve the patient's prognosis. Conclusion: It was possible to see that the management of digestive hemorrhage has to be started as early as possible, with the need to stabilize the patient with active bleeding. In addition, the use of vasoactive drugs and prophylactic antibiotic therapy are indicated in association with endoscopic treatment, which should be the first line of choice. |
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Considerations on the management of gastroesophageal varices resulting from portal hypertensionConsideraciones sobre el tratamiento de las várices gastroesofágicas derivadas de la hipertensión portalConsiderações acerca do manejo das varizes gastroesofágicas decorrentes da hipertensão portalVárices esofágicasHipertensión portalHemorragia.Varizes esofagianasHipertensão portalHemorragia.Esophageal varicesPortal hypertensionHemorrhage.Introduction: Liver cirrhosis is currently the leading cause of portal hypertension, which is a clinical condition with many pathophysiological consequences. In this sense, the approach to gastroesophageal varices resulting from this condition represents a clinical entity of great relevance to the medical scenario. Objectives: The objetive of this study was to evaluate the clinical, epidemiological and pathophysiological aspects of esophageal varices resulting from portal hypertension, building knowledge based on case reports and knowledge based on the literature. Materials and Methods: This is an integrative literature review on the general clinical characteristics of esophageal varices. The PICO strategy was used to develop the guiding question. In addition, the descriptors "Esophageal Varices"; "Portal Hypertension"; "Propaedeutics" were cross-referenced in the National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (SCIELO), Ebscohost, Google Scholar and Virtual Health Library (VHL) databases. Results and Discussion: A significant proportion of the articles showed that variceal upper gastrointestinal bleeding results from the alterations caused by portal hypertension and that it must be managed incisively in order to improve the patient's prognosis. Conclusion: It was possible to see that the management of digestive hemorrhage has to be started as early as possible, with the need to stabilize the patient with active bleeding. In addition, the use of vasoactive drugs and prophylactic antibiotic therapy are indicated in association with endoscopic treatment, which should be the first line of choice.Introducción: La cirrosis hepática es actualmente la principal causa de hipertensión portal, que es una condición clínica con muchas consecuencias fisiopatológicas. En este sentido, el abordaje de las varices gastroesofágicas derivadas de esta condición representa una entidad clínica de gran relevancia en el escenario médico. Objetivo: El objetivo de este estudio fue evaluar los aspectos clínicos, epidemiológicos y fisiopatológicos de las várices esofágicas resultantes de la hipertensión portal, construyendo conocimiento basado en relatos de casos y conocimiento basado en la literatura. Materiales y métodos: Se trata de una revisión bibliográfica integradora sobre las características clínicas generales de las varices esofágicas. Se utilizó la estrategia PICO para desarrollar la pregunta guía. Además, se cruzaron los descriptores "Várices esofágicas"; "Hipertensión portal"; "Propedéutica" en las bases de datos National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (SCIELO), Ebscohost, Google Scholar y Virtual Health Library (BVS). Resultados y Discusión: Una proporción significativa de los artículos mostró que la hemorragia digestiva alta por varices es el resultado de las alteraciones causadas por la hipertensión portal y que debe ser manejada de forma incisiva para mejorar el pronóstico del paciente. Conclusión: Se pudo comprobar que el manejo de la hemorragia digestiva debe iniciarse lo más precozmente posible, siendo necesario estabilizar al paciente con hemorragia activa. Además, el uso de fármacos vasoactivos y la antibioticoterapia profiláctica están indicados en asociación con el tratamiento endoscópico, que debe ser la primera línea de elección.Introdução: A cirrose hepática representa, hoje, a maior causa de hipertensão portal, sendo esta uma condição clínica com muitos desdobramentos fisiopatológicos. Nesse sentido, a abordagem das varizes gastroesofágicas decorrentes dessa condição representa uma entidade clínica de grande relevância para o cenário médico. Objetivo: O presente estudo teve como objetivo avaliar os aspectos clínicos, epidemiológicos e fisiopatológicos das varizes esofagianas decorrentes da hipertensão portal, alicerçando a construção do conhecimento com base em relatos de casos e conhecimento sedimentado na literatura. Materiais e Métodos: Trata-se de uma revisão integrativa de literatura acerca das características clínicas gerais sobre das varizes esofagianas. Utilizou-se a estratégia PICO para a elaboração da pergunta norteadora. Ademais, realizou-se o cruzamento dos descritores “Varizes Esofagianas”; “Hipertensão Portal”; “Propedêutica”, nas bases de dados National Library of Medicine (PubMed MEDLINE), Scientific Eletronic Library Online (SCIELO), Ebscohost, Google Scholar e Biblioteca Virtual de Saúde (BVS). Resultados e Discussão: Uma parcela significativa dos artigos demonstrou que a hemorragia digestiva alta varicosa decorre das alterações provocadas pela hipertensão portal e ainda que o seu manejo deve ser realizado de forma incisiva, com o intuito de melhorar o prognóstico do paciente. Conclusão: Foi possível perceber que o manejo da hemorragia digestiva tem que ser iniciado o mais precocemente possível, havendo a necessidade de se estabilizar o paciente com sangramento ativo. Além disso, a utilização de drogas vasoativas e da antibioticoterapia profilática são indicadas em associação com o tratamento endoscópico, o qual deve ser a primeira linha de escolha.Research, Society and Development2024-03-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4530210.33448/rsd-v13i3.45302Research, Society and Development; Vol. 13 No. 3; e7513345302Research, Society and Development; Vol. 13 Núm. 3; e7513345302Research, Society and Development; v. 13 n. 3; e75133453022525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/45302/36132Copyright (c) 2024 Tiago Mouallem Rennó ; Renan Rosa de Miranda; Alana Silva Monteiro; Rayssa Silva Corrêa; Ana Clara Vargas Consoli Almeidahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRennó , Tiago Mouallem Miranda, Renan Rosa de Monteiro, Alana Silva Corrêa, Rayssa Silva Almeida, Ana Clara Vargas Consoli 2024-04-04T18:36:46Zoai:ojs.pkp.sfu.ca:article/45302Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-04-04T18:36:46Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Considerations on the management of gastroesophageal varices resulting from portal hypertension Consideraciones sobre el tratamiento de las várices gastroesofágicas derivadas de la hipertensión portal Considerações acerca do manejo das varizes gastroesofágicas decorrentes da hipertensão portal |
title |
Considerations on the management of gastroesophageal varices resulting from portal hypertension |
spellingShingle |
Considerations on the management of gastroesophageal varices resulting from portal hypertension Rennó , Tiago Mouallem Várices esofágicas Hipertensión portal Hemorragia. Varizes esofagianas Hipertensão portal Hemorragia. Esophageal varices Portal hypertension Hemorrhage. |
title_short |
Considerations on the management of gastroesophageal varices resulting from portal hypertension |
title_full |
Considerations on the management of gastroesophageal varices resulting from portal hypertension |
title_fullStr |
Considerations on the management of gastroesophageal varices resulting from portal hypertension |
title_full_unstemmed |
Considerations on the management of gastroesophageal varices resulting from portal hypertension |
title_sort |
Considerations on the management of gastroesophageal varices resulting from portal hypertension |
author |
Rennó , Tiago Mouallem |
author_facet |
Rennó , Tiago Mouallem Miranda, Renan Rosa de Monteiro, Alana Silva Corrêa, Rayssa Silva Almeida, Ana Clara Vargas Consoli |
author_role |
author |
author2 |
Miranda, Renan Rosa de Monteiro, Alana Silva Corrêa, Rayssa Silva Almeida, Ana Clara Vargas Consoli |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Rennó , Tiago Mouallem Miranda, Renan Rosa de Monteiro, Alana Silva Corrêa, Rayssa Silva Almeida, Ana Clara Vargas Consoli |
dc.subject.por.fl_str_mv |
Várices esofágicas Hipertensión portal Hemorragia. Varizes esofagianas Hipertensão portal Hemorragia. Esophageal varices Portal hypertension Hemorrhage. |
topic |
Várices esofágicas Hipertensión portal Hemorragia. Varizes esofagianas Hipertensão portal Hemorragia. Esophageal varices Portal hypertension Hemorrhage. |
description |
Introduction: Liver cirrhosis is currently the leading cause of portal hypertension, which is a clinical condition with many pathophysiological consequences. In this sense, the approach to gastroesophageal varices resulting from this condition represents a clinical entity of great relevance to the medical scenario. Objectives: The objetive of this study was to evaluate the clinical, epidemiological and pathophysiological aspects of esophageal varices resulting from portal hypertension, building knowledge based on case reports and knowledge based on the literature. Materials and Methods: This is an integrative literature review on the general clinical characteristics of esophageal varices. The PICO strategy was used to develop the guiding question. In addition, the descriptors "Esophageal Varices"; "Portal Hypertension"; "Propaedeutics" were cross-referenced in the National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (SCIELO), Ebscohost, Google Scholar and Virtual Health Library (VHL) databases. Results and Discussion: A significant proportion of the articles showed that variceal upper gastrointestinal bleeding results from the alterations caused by portal hypertension and that it must be managed incisively in order to improve the patient's prognosis. Conclusion: It was possible to see that the management of digestive hemorrhage has to be started as early as possible, with the need to stabilize the patient with active bleeding. In addition, the use of vasoactive drugs and prophylactic antibiotic therapy are indicated in association with endoscopic treatment, which should be the first line of choice. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-03-19 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/45302 10.33448/rsd-v13i3.45302 |
url |
https://rsdjournal.org/index.php/rsd/article/view/45302 |
identifier_str_mv |
10.33448/rsd-v13i3.45302 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/45302/36132 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 13 No. 3; e7513345302 Research, Society and Development; Vol. 13 Núm. 3; e7513345302 Research, Society and Development; v. 13 n. 3; e7513345302 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052639055183872 |