Aspectos atuais sobre a seleção dos pacientes candidatos ao transplante pulmonar

• Autor(a) principal: Oliveira, Flávia Demartine Borges de
• Data de Publicação: 2023
• Outros Autores: Guimarães, Gabriela Peres, Calderari, Yasmin, Corrêa, Letícia Leite, Castro, André Mendonça de, Machado, Helena Piton, Troya, Juliana, Peruzzi, Viviane Bonato, Socorro, Ana Júlia Silva, Oliveira, Maria Eduarda Osório de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/43832
• topic: Trasplante de pulmón; Selección; Contra indicaciones.; Transplante de pulmão; Seleção; Contraindicações.; Lung transplantation; Selection; Contraindications.

Currently, the main indications for lung transplantation worldwide are chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, cystic fibrosis, alpha-1-antitrypsin (alpha-1) deficiency, idiopathic pulmonary arterial hypertension, bronchiectasis, retransplantation, sarcoidosis and severe lung injury caused by COVID-19, and these candidates must demonstrate knowledge regarding the procedure, good adherence to the medical treatment performed, adequate psychosocial structure and family support. Furthermore, the proper assessment of contraindications contributes to a lower occurrence of unfavorable clinical outcomes unrelated to the graft, benefiting patients with a greater chance of success and, thus, improving overall survival with treatment. Among the absolute contraindications, lung cancer, cardiac dysfunction unrelated to lung disease, significant organic dysfunction of any other noble organ, hepatitis B and C virus infections, active pulmonary tuberculosis and severe rib cage deformity stand out. Furthermore, among the relative contraindications, there is age over 65 years, severe clinical instability, HIV infection, obesity, severe osteoporosis and decompensated systemic diseases.