Comparison of the clinical profile of two groups of patients who underwent the Brain Death protocol
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/33807 |
Resumo: | Introduction: Brain death (BD) is the irreversible cessation of the functions of intracranial neurological structures, fulfilling prerequisites such as coma with known and irreversible cause; absence of hypothermia, hypotension or severe metabolic disorder and exclusion of intoxication or depressive effect of the central nervous system. Methodology: Approved by the Research Ethics Committee (CEP/ UFU), used data from patients of the Adult Intensive Care Unit of the Hospital de Clínicas of the Federal University of Uberlândia (UTIA/ HC-UFU) in a state of coma for which the Brain Death Diagnostic Protocol was opened with graphic examination, proceeding descriptive and statistical analysis. Results: present male profile, aged >41 years, born in other municipalities, with complete elementary school. Presenting 52.68% of the cases of etiology by TBI, from traffic accident 23.65%, 7.53%, gunshot wound 6.45%, beating 5.38% and other 21.51%; most did not have comorbidities (50.53%)and alcoholism also appear in greater percentage and age over 44 years. Discussion: The main causes of ED were cranioencephalic trauma (TBI), stroke (CVA) and ischemic hypoxia (HI) after cardiac arrest. All open protocols for diagnosis of BD evolved to death, and no case of opening of the protocol with improvement of the individual was found. Conclusion: the predominant profile was greater than 40 years, residents outside Uberlândia and of average schooling consisting of complete elementary school, victims of stroke or trauma, in use of sedatives, with significant increase of CO2 pressure and reduction of O2 pressure (p <0.001) between the beginning of hospitalization and the outcome of the condition. The main findings of the patients admitted were the presence of comorbidities, the use of sedatives and significant worsening in laboratory tests. |
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Comparison of the clinical profile of two groups of patients who underwent the Brain Death protocolComparación del perfil clínico de dos grupos de pacientes que fueron sometidos al protocolo de Muerte EncefálicaComparação do perfil clínico de dois grupos de pacientes que foram submetidos ao protocolo de Morte Encefálica Muerte encefálicaPerfil clínicoProtocolo.Brain deathClinical profileProtocol.Morte encefálicaPerfil clínicoProtocolo. Introduction: Brain death (BD) is the irreversible cessation of the functions of intracranial neurological structures, fulfilling prerequisites such as coma with known and irreversible cause; absence of hypothermia, hypotension or severe metabolic disorder and exclusion of intoxication or depressive effect of the central nervous system. Methodology: Approved by the Research Ethics Committee (CEP/ UFU), used data from patients of the Adult Intensive Care Unit of the Hospital de Clínicas of the Federal University of Uberlândia (UTIA/ HC-UFU) in a state of coma for which the Brain Death Diagnostic Protocol was opened with graphic examination, proceeding descriptive and statistical analysis. Results: present male profile, aged >41 years, born in other municipalities, with complete elementary school. Presenting 52.68% of the cases of etiology by TBI, from traffic accident 23.65%, 7.53%, gunshot wound 6.45%, beating 5.38% and other 21.51%; most did not have comorbidities (50.53%)and alcoholism also appear in greater percentage and age over 44 years. Discussion: The main causes of ED were cranioencephalic trauma (TBI), stroke (CVA) and ischemic hypoxia (HI) after cardiac arrest. All open protocols for diagnosis of BD evolved to death, and no case of opening of the protocol with improvement of the individual was found. Conclusion: the predominant profile was greater than 40 years, residents outside Uberlândia and of average schooling consisting of complete elementary school, victims of stroke or trauma, in use of sedatives, with significant increase of CO2 pressure and reduction of O2 pressure (p <0.001) between the beginning of hospitalization and the outcome of the condition. The main findings of the patients admitted were the presence of comorbidities, the use of sedatives and significant worsening in laboratory tests.Introducción: Muerte encefálica (ME) es el cese irreversible de las funciones de las estructuras neurológicas intracraneales, cumpliendo prerrequisitos como coma con causa conocida e irreversible; ausencia de hipotermia, hipotensión o trastorno metabólico grave y exclusión de intoxicación o efecto depresivo del sistema nervioso central. Metodología: Aprobado por el Comité de Ética en Investigación (CEP/UFU), utilizó datos de pacientes de la Unidad de Terapia Intensiva Adulto del Hospital de Clínicas de la Universidad Federal de Uberlândia (UTIA/HC-UFU) en estado de coma para los cuales se abrió el Protocolo de diagnóstico de Muerte Encefálica con realización de examen gráfico, procediendo análisis descriptivo y estadístico. Resultados: presentan perfil del sexo masculino, con edad >41 años, natural de otros municipios, con enseñanza primaria completa. Presentando 52,68% de los casos de etiología por TCE, proveniente de accidente tránsito 23,65%, atropello 7,53%, herida por proyectil de arma de fuego 6,45%, paliza 5,38% y otros 21,51%; la mayoría no poseía comorbilidades (50,53%) siendo que cuando presentes la HAS y el etilismo también aparecen en mayor porcentaje y en edad encima de 44 años. Discusión: Las principales causas de ME fueron trauma craneoencefálico (TCE), accidente cerebrovascular (AVC) e hipoxia isquémica (HI) post paro cardíaco. Todos los protocolos abiertos para diagnóstico de ME evolucionaron a muerte, no habiendo sido encontrado ningún caso de apertura del protocolo con mejora del individuo. Conclusión: el perfil predominante fue mayor que 40 años, residentes fuera de Uberlândia y de escolaridad media constando enseñanza primaria completa, víctimas de accidentes cerebrovasculares o trauma, en uso de sedativos, con aumento significativo de la presión de CO2 y reducción de la presión de O2 (p<0,001) entre el inicio de la hospitalización y el desenlace del cuadro. Los principales hallazgos de los pacientes admitidos fueron la presencia de comorbilidades, el uso de sedantes y empeora significativa en exámenes de laboratorio.Introdução: Morte encefálica (ME) é a cessação irreversível das funções das estruturas neurológicas intracranianas, cumprindo pré-requisitos como coma com causa conhecida e irreversível; ausência de hipotermia, hipotensão ou distúrbio metabólico grave e exclusão de intoxicação ou efeito depressor do sistema nervoso central. Metodologia: Aprovado pelo Comitê de Ética em Pesquisa (CEP/UFU), utilizou dados de pacientes da Unidade de Terapia Intensiva Adulto do Hospital de Clínicas da Universidade Federal de Uberlândia (UTIA/HC-UFU) em estado de coma para os quais foi aberto o Protocolo de diagnóstico de Morte Encefálica com realização de exame gráfico, procedendo análise descritiva e estatística. Resultados: apresentam perfil do sexo masculino, com idade >41 anos, natural de outros municípios, com ensino fundamental completo. Apresentando 52,68% dos casos de etiologia por TCE, proveniente de acidente trânsito 23,65%, atropelamento 7,53%, ferimento por projétil de arma de fogo 6,45%, espancamento 5,38% e outros 21,51 %; a maioria não possuía comorbidades (50,53%), sendo que quando presentes a HAS e o etilismo também aparecem em maior porcentagem e em idade acima de 44 anos. Discussão: As principais causas de ME foram trauma cranioencefálico (TCE), acidente vascular cerebral (AVC) e hipóxia isquêmica (HI) pós parada cardíaca. Todos os protocolos abertos para diagnóstico de ME evoluíram a óbito, não tendo sido encontrado nenhum caso de abertura do protocolo com melhora do indivíduo. Conclusão: o perfil predominante foi maior que 40 anos, residentes fora de Uberlândia e de escolaridade média constando ensino fundamental completo, vítimas de AVC ou trauma, em uso de sedativos, com aumento significativo da pressão de CO2 e redução da pressão de O2 (p<0,001) entre o início da internação e o desfecho do quadro. Os principais achados dos pacientes admitidos foram a presença de comorbidades, o uso de sedativos e piora significativa em exames laboratoriais.Research, Society and Development2022-08-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3380710.33448/rsd-v11i11.33807Research, Society and Development; Vol. 11 No. 11; e386111133807Research, Society and Development; Vol. 11 Núm. 11; e386111133807Research, Society and Development; v. 11 n. 11; e3861111338072525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/33807/28537Copyright (c) 2022 Liliana Silva; Francisco Edes da Silva Pinheiro; Nathália Varano; Ana Jullia Felipe de Paula Carrilho; João-Batista Destro-Filhohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, LilianaPinheiro, Francisco Edes da SilvaVarano, NatháliaCarrilho, Ana Jullia Felipe de PaulaDestro-Filho, João-Batista2022-09-05T13:24:46Zoai:ojs.pkp.sfu.ca:article/33807Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:49:21.267517Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Comparison of the clinical profile of two groups of patients who underwent the Brain Death protocol Comparación del perfil clínico de dos grupos de pacientes que fueron sometidos al protocolo de Muerte Encefálica Comparação do perfil clínico de dois grupos de pacientes que foram submetidos ao protocolo de Morte Encefálica |
title |
Comparison of the clinical profile of two groups of patients who underwent the Brain Death protocol |
spellingShingle |
Comparison of the clinical profile of two groups of patients who underwent the Brain Death protocol Silva, Liliana Muerte encefálica Perfil clínico Protocolo. Brain death Clinical profile Protocol. Morte encefálica Perfil clínico Protocolo. |
title_short |
Comparison of the clinical profile of two groups of patients who underwent the Brain Death protocol |
title_full |
Comparison of the clinical profile of two groups of patients who underwent the Brain Death protocol |
title_fullStr |
Comparison of the clinical profile of two groups of patients who underwent the Brain Death protocol |
title_full_unstemmed |
Comparison of the clinical profile of two groups of patients who underwent the Brain Death protocol |
title_sort |
Comparison of the clinical profile of two groups of patients who underwent the Brain Death protocol |
author |
Silva, Liliana |
author_facet |
Silva, Liliana Pinheiro, Francisco Edes da Silva Varano, Nathália Carrilho, Ana Jullia Felipe de Paula Destro-Filho, João-Batista |
author_role |
author |
author2 |
Pinheiro, Francisco Edes da Silva Varano, Nathália Carrilho, Ana Jullia Felipe de Paula Destro-Filho, João-Batista |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Silva, Liliana Pinheiro, Francisco Edes da Silva Varano, Nathália Carrilho, Ana Jullia Felipe de Paula Destro-Filho, João-Batista |
dc.subject.por.fl_str_mv |
Muerte encefálica Perfil clínico Protocolo. Brain death Clinical profile Protocol. Morte encefálica Perfil clínico Protocolo. |
topic |
Muerte encefálica Perfil clínico Protocolo. Brain death Clinical profile Protocol. Morte encefálica Perfil clínico Protocolo. |
description |
Introduction: Brain death (BD) is the irreversible cessation of the functions of intracranial neurological structures, fulfilling prerequisites such as coma with known and irreversible cause; absence of hypothermia, hypotension or severe metabolic disorder and exclusion of intoxication or depressive effect of the central nervous system. Methodology: Approved by the Research Ethics Committee (CEP/ UFU), used data from patients of the Adult Intensive Care Unit of the Hospital de Clínicas of the Federal University of Uberlândia (UTIA/ HC-UFU) in a state of coma for which the Brain Death Diagnostic Protocol was opened with graphic examination, proceeding descriptive and statistical analysis. Results: present male profile, aged >41 years, born in other municipalities, with complete elementary school. Presenting 52.68% of the cases of etiology by TBI, from traffic accident 23.65%, 7.53%, gunshot wound 6.45%, beating 5.38% and other 21.51%; most did not have comorbidities (50.53%)and alcoholism also appear in greater percentage and age over 44 years. Discussion: The main causes of ED were cranioencephalic trauma (TBI), stroke (CVA) and ischemic hypoxia (HI) after cardiac arrest. All open protocols for diagnosis of BD evolved to death, and no case of opening of the protocol with improvement of the individual was found. Conclusion: the predominant profile was greater than 40 years, residents outside Uberlândia and of average schooling consisting of complete elementary school, victims of stroke or trauma, in use of sedatives, with significant increase of CO2 pressure and reduction of O2 pressure (p <0.001) between the beginning of hospitalization and the outcome of the condition. The main findings of the patients admitted were the presence of comorbidities, the use of sedatives and significant worsening in laboratory tests. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-08-25 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/33807 10.33448/rsd-v11i11.33807 |
url |
https://rsdjournal.org/index.php/rsd/article/view/33807 |
identifier_str_mv |
10.33448/rsd-v11i11.33807 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/33807/28537 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 11; e386111133807 Research, Society and Development; Vol. 11 Núm. 11; e386111133807 Research, Society and Development; v. 11 n. 11; e386111133807 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052770794078208 |