Oral and systemic changes in Langerhans Cell Histiocytosis in a pediatric patient: Case report
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/14456 |
Resumo: | Langerhans Cell Histiocytosis (LCH) is a disorder associated with the proliferation of Langerhans cells. Due to its infiltrative nature, LCH can involve organs such as the skin, the ganglia, the lung and the liver. It is estimated that its incidence is approximately 5 to 10 cases in a million per year, mainly in children under 15 years old, with a predominance in males, in the proportion of 2: 1 and its pathogenesis remains unknown. The objective of this study was to describe the systemic and oral manifestations of LCH in a child, highlighting the importance of the dental surgeon in the early diagnosis of oral lesions in primary care. For the description of the clinical case, the information was obtained by consulting the patient's medical record at Hospital University Onofre Lopes - HUOL. Male patient, 4 months old, presented lesions in the oral cavity in the lower, upper alveolar ridge and hard palate, exophytic formed by erythroplastic and leukoplastic regions not removed during scraping, with abdominal distension, normotensive fontanelle, presence of parietal cephalic “nodule”, jaundice, choluria, fecal hypocholia and hyperemic genitals. We concluded that the child had a clinical condition compatible with LCH. This work also showed the importance of the dentist, especially in Primary Health Care, for the correct diagnosis of systemic diseases, with oral manifestations, as well as his responsibility in ordering care in the search for comprehensive care. |
id |
UNIFEI_e4c5afc67f50bcad364370e74b73c962 |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/14456 |
network_acronym_str |
UNIFEI |
network_name_str |
Research, Society and Development |
repository_id_str |
|
spelling |
Oral and systemic changes in Langerhans Cell Histiocytosis in a pediatric patient: Case reportCambios orales y sistémicos em la histiocitosis de células de Langerhans em um paciente pediátrico: Reporte de casoAlterações bucais e sistêmicas da Histiocitose de Células de Langerhans em paciente pediátrico: Relato de casoLangerhans Cell HistiocytosisChidrensOral PathologyPediatric dentistry.Histiocitosis de Células de LangerhansNiñosPatología BucalOdontología pediatrica.Histiocitose de Células de LangerhansCriançasPatologia BucalOdontopediatria.Langerhans Cell Histiocytosis (LCH) is a disorder associated with the proliferation of Langerhans cells. Due to its infiltrative nature, LCH can involve organs such as the skin, the ganglia, the lung and the liver. It is estimated that its incidence is approximately 5 to 10 cases in a million per year, mainly in children under 15 years old, with a predominance in males, in the proportion of 2: 1 and its pathogenesis remains unknown. The objective of this study was to describe the systemic and oral manifestations of LCH in a child, highlighting the importance of the dental surgeon in the early diagnosis of oral lesions in primary care. For the description of the clinical case, the information was obtained by consulting the patient's medical record at Hospital University Onofre Lopes - HUOL. Male patient, 4 months old, presented lesions in the oral cavity in the lower, upper alveolar ridge and hard palate, exophytic formed by erythroplastic and leukoplastic regions not removed during scraping, with abdominal distension, normotensive fontanelle, presence of parietal cephalic “nodule”, jaundice, choluria, fecal hypocholia and hyperemic genitals. We concluded that the child had a clinical condition compatible with LCH. This work also showed the importance of the dentist, especially in Primary Health Care, for the correct diagnosis of systemic diseases, with oral manifestations, as well as his responsibility in ordering care in the search for comprehensive care.La histiocitosis de células de Langerhans (LCH) es un trastorno asociado con la proliferación de células de Langerhans. Debido a su naturaleza infiltrativa, la LCH puede afectar órganos como la piel, los ganglios, el pulmón y el hígado. Se estima que su incidencia es aproximadamente de 5 a 10 casos en un millón por año, principalmente en menores de 15 años, con predominio en el sexo masculino, en la proporción de 2: 1 y su patogenia permanece desconocida. El objetivo de este estudio fue describir las manifestaciones sistémicas y bucales de la LCH en un niño, destacando la importancia del cirujano dentista en el diagnóstico precoz de las lesiones bucales en atención primaria. Para la descripción del caso clínico, la información se obtuvo consultando la historia clínica del paciente en el Hospital Universitário Onofre Lopes - HUOL. Paciente masculino de 4 meses de edad que presenta lesiones en cavidad oral en reborde alveolar superior e inferior y paladar duro, exofíticas formadas por regiones eritroplásicas y leucoplásicas no removidas durante el raspado, con distensión abdominal, fontanela normotensa, presencia de “nódulo” cefálico parietal , ictericia, coluria, hipocolía fecal y genitales hiperémicos. Concluimos que el niño presentaba un cuadro clínico compatible con LCH. Este trabajo también mostró la importancia del odontólogo, especialmente en Atención Primaria de Salud, para el correcto diagnóstico de las enfermedades sistémicas, con manifestaciones bucales, así como su responsabilidad en la ordenación de la atención en la búsqueda de una atención integral.A Histiocitose de Células de Langerhans (LCH) é uma desordem associada à proliferação das células de Langerhans. Devido à sua natureza infiltrativa, a LCH pode envolver órgãos como a pele, os gânglios, o pulmão e o fígado. Estima-se que sua incidência é de aproximadamente 5 a 10 casos em um milhão por ano, principalmente em menores de 15 anos, com predominância no sexo masculino, na proporção de 2:1 e sua patogênese permanece desconhecida. Objetivou-se com este estudo descrever as manifestações sistêmicas e orais da LCH, em uma criança, destacando a importância do cirurgião-dentista no diagnóstico precoce das lesões bucais na atenção básica. Para descrição do caso clínico, as informações foram obtidas por meio de consulta ao prontuário do paciente no Hospital Universitário Onofre Lopes – HUOL. Paciente do sexo masculino, 4 meses, apresentava lesões na cavidade oral em rebordo alveolar inferior, superior e palato duro, exofíticas formada por regiões eritroplásicas e leucoplásicas não removida durante raspagem, com distensão abdominal, fontanela normotensa, presença de “nódulo” cefálico parietal, ictérico, colúria, hipocolia fecal e genitália hiperemiada. Concluímos que a criança possuía quadro clínico compatível com LCH. Este trabalho mostrou ainda a importância do cirurgião-dentista, especialmente na Atenção Básica de saúde, para o correto diagnóstico de doenças sistêmicas, com manifestações bucais, assim como a sua responsabilidade na ordenação do cuidado na busca pela integralidade da atenção.Research, Society and Development2021-04-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1445610.33448/rsd-v10i4.14456Research, Society and Development; Vol. 10 No. 4; e48210414456Research, Society and Development; Vol. 10 Núm. 4; e48210414456Research, Society and Development; v. 10 n. 4; e482104144562525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/14456/12908Copyright (c) 2021 Chauí de Lima Cabral; Nayron Lourenço Ivo de Souza; Romário Dias da Cunha; Ana Larissa Fernandes de Holanda Soareshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCabral, Chauí de LimaSouza, Nayron Lourenço Ivo de Cunha, Romário Dias da Soares, Ana Larissa Fernandes de Holanda 2021-04-25T11:21:26Zoai:ojs.pkp.sfu.ca:article/14456Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:35:34.889814Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Oral and systemic changes in Langerhans Cell Histiocytosis in a pediatric patient: Case report Cambios orales y sistémicos em la histiocitosis de células de Langerhans em um paciente pediátrico: Reporte de caso Alterações bucais e sistêmicas da Histiocitose de Células de Langerhans em paciente pediátrico: Relato de caso |
title |
Oral and systemic changes in Langerhans Cell Histiocytosis in a pediatric patient: Case report |
spellingShingle |
Oral and systemic changes in Langerhans Cell Histiocytosis in a pediatric patient: Case report Cabral, Chauí de Lima Langerhans Cell Histiocytosis Chidrens Oral Pathology Pediatric dentistry. Histiocitosis de Células de Langerhans Niños Patología Bucal Odontología pediatrica. Histiocitose de Células de Langerhans Crianças Patologia Bucal Odontopediatria. |
title_short |
Oral and systemic changes in Langerhans Cell Histiocytosis in a pediatric patient: Case report |
title_full |
Oral and systemic changes in Langerhans Cell Histiocytosis in a pediatric patient: Case report |
title_fullStr |
Oral and systemic changes in Langerhans Cell Histiocytosis in a pediatric patient: Case report |
title_full_unstemmed |
Oral and systemic changes in Langerhans Cell Histiocytosis in a pediatric patient: Case report |
title_sort |
Oral and systemic changes in Langerhans Cell Histiocytosis in a pediatric patient: Case report |
author |
Cabral, Chauí de Lima |
author_facet |
Cabral, Chauí de Lima Souza, Nayron Lourenço Ivo de Cunha, Romário Dias da Soares, Ana Larissa Fernandes de Holanda |
author_role |
author |
author2 |
Souza, Nayron Lourenço Ivo de Cunha, Romário Dias da Soares, Ana Larissa Fernandes de Holanda |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Cabral, Chauí de Lima Souza, Nayron Lourenço Ivo de Cunha, Romário Dias da Soares, Ana Larissa Fernandes de Holanda |
dc.subject.por.fl_str_mv |
Langerhans Cell Histiocytosis Chidrens Oral Pathology Pediatric dentistry. Histiocitosis de Células de Langerhans Niños Patología Bucal Odontología pediatrica. Histiocitose de Células de Langerhans Crianças Patologia Bucal Odontopediatria. |
topic |
Langerhans Cell Histiocytosis Chidrens Oral Pathology Pediatric dentistry. Histiocitosis de Células de Langerhans Niños Patología Bucal Odontología pediatrica. Histiocitose de Células de Langerhans Crianças Patologia Bucal Odontopediatria. |
description |
Langerhans Cell Histiocytosis (LCH) is a disorder associated with the proliferation of Langerhans cells. Due to its infiltrative nature, LCH can involve organs such as the skin, the ganglia, the lung and the liver. It is estimated that its incidence is approximately 5 to 10 cases in a million per year, mainly in children under 15 years old, with a predominance in males, in the proportion of 2: 1 and its pathogenesis remains unknown. The objective of this study was to describe the systemic and oral manifestations of LCH in a child, highlighting the importance of the dental surgeon in the early diagnosis of oral lesions in primary care. For the description of the clinical case, the information was obtained by consulting the patient's medical record at Hospital University Onofre Lopes - HUOL. Male patient, 4 months old, presented lesions in the oral cavity in the lower, upper alveolar ridge and hard palate, exophytic formed by erythroplastic and leukoplastic regions not removed during scraping, with abdominal distension, normotensive fontanelle, presence of parietal cephalic “nodule”, jaundice, choluria, fecal hypocholia and hyperemic genitals. We concluded that the child had a clinical condition compatible with LCH. This work also showed the importance of the dentist, especially in Primary Health Care, for the correct diagnosis of systemic diseases, with oral manifestations, as well as his responsibility in ordering care in the search for comprehensive care. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-04-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/14456 10.33448/rsd-v10i4.14456 |
url |
https://rsdjournal.org/index.php/rsd/article/view/14456 |
identifier_str_mv |
10.33448/rsd-v10i4.14456 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/14456/12908 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 4; e48210414456 Research, Society and Development; Vol. 10 Núm. 4; e48210414456 Research, Society and Development; v. 10 n. 4; e48210414456 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
_version_ |
1797052675287678976 |