A literature review on the use of Chamomile (Matricaria recutita L.) in the treatment of Generalized Anxiety Disorder
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/28680 |
Resumo: | Generalized anxiety disorder affects a significant portion of the world population, for its treatment benzodiazepine drugs are used, which have a high rate of side effects and chemical dependence. Thus, the population seeks alternative treatments to treat the disease, such as through traditional herbal products, including Matricaria recutita L. (chamomile), which has a low probability of adverse reaction. The objective of this work was to carry out a literature review of articles published from the years 2000 to 2022, which report the use of chamomile in the treatment of anxiety. For this, 4 databases were selected, having as markers the keywords: “chamomile”, “chamomile & anxiolytic”, “chamomile & anxiety”, “chamomile & sedative”; and only the works that met the inclusion criteria were analyzed. Altogether, 16 scientific studies were used for the construction of this review, including clinical and pre-clinical trials, as well as review articles already published. The analysis parameters, such as pharmacological properties of the plant, treatment purposes and evidence of action through in vivo, in vitro and in silico studies, could be observed through the complete reading of the selected articles, highlighting the anxiolytic effect of chamomile granted by secondary metabolites of the flavonoid class. It was also evidenced the scarcity of research on the therapeutic effects of the herb, where this fact is linked to the devaluation of popular medicine. |
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A literature review on the use of Chamomile (Matricaria recutita L.) in the treatment of Generalized Anxiety DisorderUna revisión de la literatura sobre el uso de la Manzanilla (Matricaria recutita L.) en el tratamiento del Trastorno de Ansiedad GeneralizadaUma revisão bibliográfica sobre a utilização da Camomila (Matricaria recutita L.) no tratamento do Transtorno de Ansiedade GeneralizadaChamomileAnxiolyticAnxietyHerbal medicine.ManzanillaAnsiolíticoAnsiedadMedicina herbaria.CamomilaAnsiolíticoAnsiedadeFitoterápicoEnsino.Generalized anxiety disorder affects a significant portion of the world population, for its treatment benzodiazepine drugs are used, which have a high rate of side effects and chemical dependence. Thus, the population seeks alternative treatments to treat the disease, such as through traditional herbal products, including Matricaria recutita L. (chamomile), which has a low probability of adverse reaction. The objective of this work was to carry out a literature review of articles published from the years 2000 to 2022, which report the use of chamomile in the treatment of anxiety. For this, 4 databases were selected, having as markers the keywords: “chamomile”, “chamomile & anxiolytic”, “chamomile & anxiety”, “chamomile & sedative”; and only the works that met the inclusion criteria were analyzed. Altogether, 16 scientific studies were used for the construction of this review, including clinical and pre-clinical trials, as well as review articles already published. The analysis parameters, such as pharmacological properties of the plant, treatment purposes and evidence of action through in vivo, in vitro and in silico studies, could be observed through the complete reading of the selected articles, highlighting the anxiolytic effect of chamomile granted by secondary metabolites of the flavonoid class. It was also evidenced the scarcity of research on the therapeutic effects of the herb, where this fact is linked to the devaluation of popular medicine.El trastorno de ansiedad generalizada afecta a una parte importante de la población mundial, para su tratamiento se utilizan fármacos benzodiazepínicos, los cuales presentan un alto índice de efectos secundarios y dependencia química. Así, la población busca tratamientos alternativos para tratar la enfermedad, como por ejemplo a través de productos herbolarios tradicionales, entre ellos Matricaria recutita L. (manzanilla), que tiene baja probabilidad de reacción adversa. El objetivo de este trabajo fue realizar una revisión bibliográfica de artículos publicados desde los años 2000 al 2022, que reporten el uso de la manzanilla en el tratamiento de la ansiedad. Para ello, se seleccionaron 4 bases de datos, teniendo como marcadores las palabras clave: “chamomile”, “chamomile & ansiolytic”, “chamomile & ansiedad”, “chamomile & sedative”; y solo se analizaron los trabajos que cumplieron con los criterios de inclusión. En total, se utilizaron 16 estudios científicos para la construcción de esta revisión, incluidos ensayos clínicos y preclínicos, así como artículos de revisión ya publicados. Los parámetros de análisis, tales como propiedades farmacológicas de la planta, propósitos del tratamiento y evidencia de acción a través de estudios in vivo, in vitro e in silico, se pudieron observar a través de la lectura completa de los artículos seleccionados, destacando el efecto ansiolítico de la Manzanilla otorgado por estudios secundarios. metabolitos de la clase de los flavonoides. También se evidenció la escasez de investigaciones sobre los efectos terapéuticos de la hierba, donde este hecho se vincula a la desvalorización de la medicina popular.O transtorno de ansiedade generalizada acomete uma parcela significativa da população mundial, para seu tratamento utiliza-se medicamentos benzodiazepínicos, que possuem uma alta taxa de efeitos colaterais e dependência química. Desse modo, a população busca tratamentos alternativos para tratar a doença, como por exemplo, através dos produtos tradicionais fitoterápicos, dentre esses a Matricaria recutita L. (Camomila), que possui uma baixa probabilidade de reação adversa. O objetivo deste trabalho foi realizar ums revisão bibliográfica dos artigos publicados dos anos 2000 a 2022, que relatam a utilização da Camomila no tratamento da ansiedade. Para isso foram selecionadas 4 bases de dados, tendo como marcadores as palavras-chaves: “chamomile”, “chamomile & anxiolytic”, “chamomile & anxiety”, “chamomile & sedative”; e analisados somente os trabalhos que atenderam aos critérios de inclusão. Ao todo, foram utilizados para construção desta revisão 16 estudos científicos, dentre esses, ensaios clínicos e pré-clínicos, assim como artigos de revisão já publicados. Os parâmetros de análise, como propriedades farmacológicas da planta, fins de tratamento e comprovações de ação por meio de estudos in vivo, in vitro e in silico, puderam ser observados através da leitura completa dos artigos selecionados, destacando-se o efeito ansiolítico da Camomila concedido por metabolitos secundários da classe dos flavonóides. Evidenciou-se também, a escassez de pesquisas acerca dos efeitos terapêuticos da erva, onde tal fato atrela-se a desvalorização da medicina popular.Research, Society and Development2022-04-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2868010.33448/rsd-v11i5.28680Research, Society and Development; Vol. 11 No. 5; e56811528680Research, Society and Development; Vol. 11 Núm. 5; e56811528680Research, Society and Development; v. 11 n. 5; e568115286802525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/28680/24861Copyright (c) 2022 Natasha Alves Rocha; William da Silva Sousa; Letícia Geovanna Cartonilho Siqueira; Penina Sousa Mourão; Maria Karina da Silva ; Luis Fernando Guimarães Noleto ; Mariana Oliveira Cardoso Nascimento ; Marly Lopes de Oliveira; Beneilde Cabral Morais; Valdiléia Teixeira Uchôahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRocha, Natasha Alves Sousa, William da Silva Siqueira, Letícia Geovanna Cartonilho Mourão, Penina Sousa Silva , Maria Karina da Noleto , Luis Fernando Guimarães Nascimento , Mariana Oliveira Cardoso Oliveira, Marly Lopes de Morais, Beneilde Cabral Uchôa, Valdiléia Teixeira 2022-04-17T18:18:56Zoai:ojs.pkp.sfu.ca:article/28680Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:46:00.081016Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
A literature review on the use of Chamomile (Matricaria recutita L.) in the treatment of Generalized Anxiety Disorder Una revisión de la literatura sobre el uso de la Manzanilla (Matricaria recutita L.) en el tratamiento del Trastorno de Ansiedad Generalizada Uma revisão bibliográfica sobre a utilização da Camomila (Matricaria recutita L.) no tratamento do Transtorno de Ansiedade Generalizada |
| title |
A literature review on the use of Chamomile (Matricaria recutita L.) in the treatment of Generalized Anxiety Disorder |
| spellingShingle |
A literature review on the use of Chamomile (Matricaria recutita L.) in the treatment of Generalized Anxiety Disorder Rocha, Natasha Alves Chamomile Anxiolytic Anxiety Herbal medicine. Manzanilla Ansiolítico Ansiedad Medicina herbaria. Camomila Ansiolítico Ansiedade Fitoterápico Ensino. |
| title_short |
A literature review on the use of Chamomile (Matricaria recutita L.) in the treatment of Generalized Anxiety Disorder |
| title_full |
A literature review on the use of Chamomile (Matricaria recutita L.) in the treatment of Generalized Anxiety Disorder |
| title_fullStr |
A literature review on the use of Chamomile (Matricaria recutita L.) in the treatment of Generalized Anxiety Disorder |
| title_full_unstemmed |
A literature review on the use of Chamomile (Matricaria recutita L.) in the treatment of Generalized Anxiety Disorder |
| title_sort |
A literature review on the use of Chamomile (Matricaria recutita L.) in the treatment of Generalized Anxiety Disorder |
| author |
Rocha, Natasha Alves |
| author_facet |
Rocha, Natasha Alves Sousa, William da Silva Siqueira, Letícia Geovanna Cartonilho Mourão, Penina Sousa Silva , Maria Karina da Noleto , Luis Fernando Guimarães Nascimento , Mariana Oliveira Cardoso Oliveira, Marly Lopes de Morais, Beneilde Cabral Uchôa, Valdiléia Teixeira |
| author_role |
author |
| author2 |
Sousa, William da Silva Siqueira, Letícia Geovanna Cartonilho Mourão, Penina Sousa Silva , Maria Karina da Noleto , Luis Fernando Guimarães Nascimento , Mariana Oliveira Cardoso Oliveira, Marly Lopes de Morais, Beneilde Cabral Uchôa, Valdiléia Teixeira |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Rocha, Natasha Alves Sousa, William da Silva Siqueira, Letícia Geovanna Cartonilho Mourão, Penina Sousa Silva , Maria Karina da Noleto , Luis Fernando Guimarães Nascimento , Mariana Oliveira Cardoso Oliveira, Marly Lopes de Morais, Beneilde Cabral Uchôa, Valdiléia Teixeira |
| dc.subject.por.fl_str_mv |
Chamomile Anxiolytic Anxiety Herbal medicine. Manzanilla Ansiolítico Ansiedad Medicina herbaria. Camomila Ansiolítico Ansiedade Fitoterápico Ensino. |
| topic |
Chamomile Anxiolytic Anxiety Herbal medicine. Manzanilla Ansiolítico Ansiedad Medicina herbaria. Camomila Ansiolítico Ansiedade Fitoterápico Ensino. |
| description |
Generalized anxiety disorder affects a significant portion of the world population, for its treatment benzodiazepine drugs are used, which have a high rate of side effects and chemical dependence. Thus, the population seeks alternative treatments to treat the disease, such as through traditional herbal products, including Matricaria recutita L. (chamomile), which has a low probability of adverse reaction. The objective of this work was to carry out a literature review of articles published from the years 2000 to 2022, which report the use of chamomile in the treatment of anxiety. For this, 4 databases were selected, having as markers the keywords: “chamomile”, “chamomile & anxiolytic”, “chamomile & anxiety”, “chamomile & sedative”; and only the works that met the inclusion criteria were analyzed. Altogether, 16 scientific studies were used for the construction of this review, including clinical and pre-clinical trials, as well as review articles already published. The analysis parameters, such as pharmacological properties of the plant, treatment purposes and evidence of action through in vivo, in vitro and in silico studies, could be observed through the complete reading of the selected articles, highlighting the anxiolytic effect of chamomile granted by secondary metabolites of the flavonoid class. It was also evidenced the scarcity of research on the therapeutic effects of the herb, where this fact is linked to the devaluation of popular medicine. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-04-16 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/28680 10.33448/rsd-v11i5.28680 |
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por |
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https://rsdjournal.org/index.php/rsd/article/view/28680/24861 |
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Research, Society and Development |
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Research, Society and Development; Vol. 11 No. 5; e56811528680 Research, Society and Development; Vol. 11 Núm. 5; e56811528680 Research, Society and Development; v. 11 n. 5; e56811528680 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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