Analysis of the use of potentially inappropriate medication in elderly hospitalized in an Intensive Care Unit in a large hospital in Recife

Detalhes bibliográficos
Autor(a) principal: Neves, Anna Carolinne Santana
Data de Publicação: 2022
Outros Autores: Vasconcelos, Alan Lucena de, Lins, Maria do Carmo Lencastre de Menezes e Cruz Dueire, Almeida, Victor Avelino de, Silva, Aurylanne Mikaelle Brandão
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/30749
Resumo: Aim: To analyze the use of potentially inappropriate drugs prescribed to the elderly in Intensive Care Units. Methodology: Observational, descriptive, cross-sectional and retrospective study. The study was carried out by analyzing the electronic medical records of patients over 60 years of age, using potentially inappropriate drugs in the elderly with action on the central nervous system. Clinical and sociodemographic data were collected, as well as data regarding the use of these drugs (active pharmaceutical ingredient, drug class, treatment time, clinical indication and adverse reactions). Results: The most prescribed therapeutic classes were benzodiazepines, antipsychotics and hypnotics. Among the uses, 7.6% had no clinical justification, and the other justifications included medication reconciliation, hyperactive delirium, weaning from sedation and insomnia as the most frequent. Adverse reactions such as lowered level of consciousness, daytime sleepiness, constipation, mental confusion, and others have been observed. The results obtained are in agreement with the expected results regarding the possibility of contributing to the discussion on the current scenario of the use of potentially inappropriate drugs for the elderly in Intensive Care Units and possible perspectives and therapeutic alternatives. Conclusion: It is important to emphasize the importance of monitoring the use of these drugs when their use is unavoidable, as well as avoiding or reducing their prescription, associating other therapies with lower risk, in view of the potential harmful effects of inappropriate drugs.
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spelling Analysis of the use of potentially inappropriate medication in elderly hospitalized in an Intensive Care Unit in a large hospital in RecifeAnálisis del uso de medicación potencialmente inapropiada en ancianos hospitalizados en una Unidad De Cuidados Intensivos en un gran hospital de RecifeAnálise do uso de medicamentos potencialmente inapropriados em idosos internados em Unidade de Terapia Intensiva em um hospital de grande porte em RecifeCritérios de BeersGeriatriaGerontologiaPrescriçãoUnidade de Terapia Intensiva.Beers CriteriaGeriatricsGerontologyPrescriptionIntensive Care Unit.Criterios de BeersGeriatriaGerontologiaPrescripciónUnidad de Cuidados Intensivos.Aim: To analyze the use of potentially inappropriate drugs prescribed to the elderly in Intensive Care Units. Methodology: Observational, descriptive, cross-sectional and retrospective study. The study was carried out by analyzing the electronic medical records of patients over 60 years of age, using potentially inappropriate drugs in the elderly with action on the central nervous system. Clinical and sociodemographic data were collected, as well as data regarding the use of these drugs (active pharmaceutical ingredient, drug class, treatment time, clinical indication and adverse reactions). Results: The most prescribed therapeutic classes were benzodiazepines, antipsychotics and hypnotics. Among the uses, 7.6% had no clinical justification, and the other justifications included medication reconciliation, hyperactive delirium, weaning from sedation and insomnia as the most frequent. Adverse reactions such as lowered level of consciousness, daytime sleepiness, constipation, mental confusion, and others have been observed. The results obtained are in agreement with the expected results regarding the possibility of contributing to the discussion on the current scenario of the use of potentially inappropriate drugs for the elderly in Intensive Care Units and possible perspectives and therapeutic alternatives. Conclusion: It is important to emphasize the importance of monitoring the use of these drugs when their use is unavoidable, as well as avoiding or reducing their prescription, associating other therapies with lower risk, in view of the potential harmful effects of inappropriate drugs.Objetivo: Analizar el uso de medicamentos potencialmente inapropiados prescritos a ancianos en Unidades de Cuidados Intensivos. Metodología: Estudio observacional, descriptivo, transversal y retrospectivo. El estúdio se llevó a cabo mediante el análisis de historias clínicas electrónicas de pacientes mayores de 60 años, utilizando fármacos potencialmente inapropiados en ancianos con acción sobre el sistema nervioso central. Se recogieron datos clínicos y sociodemográficos, así como datos sobre el uso de estos fármacos (principio activo, clase, tiempo de tratamiento, indicación clínica y reacciones adversas). Resultados: Las clases terapéuticas más prescritas fueron las benzodiacepinas, los antipsicóticos y los hipnóticos. Entre los usos, el 7,6% no tuvo justificación clínica, y las demás justificaciones incluyeron la conciliación de medicamentos, el delirio hiperactivo, el destete de la sedación y el insomnio como los más frecuentes. Se han observado reacciones adversas como disminución del nivel de conciencia, somnolencia diurna, estreñimiento, confusión mental y otras. Los resultados obtenidos están de acuerdo con los resultados esperados en cuanto a la posibilidad de contribuir a la discusión sobre el escenario actual del uso de medicamentos potencialmente inapropiados para los ancianos en Unidades de Cuidados Intensivos y posibles perspectivas y alternativas terapéuticas. Conclusión: Es importante resaltar la importancia de monitorear el uso de estos medicamentos cuando su uso es inevitable, así como evitar o reducir su prescripción, asociando otras terapias con menor riesgo, ante los potenciales efectos nocivos de los medicamentos inapropiados.Objetivo: Analisar o uso de medicamentos potencialmente inapropriados prescritos a idosos em Unidades de Terapia Intensiva. Metodologia: Estudo observacional, descritivo, transversal e retrospectivo. Foi realizado por meio de análise de prontuários eletrônicos de pacientes com mais de 60 anos, em uso de medicamentos potencialmente inapropriados em idosos com ação no sistema nervoso central. Foram coletados dados clínicos e sóciodemográficos, bem como dados referentes ao uso destes medicamentos (princípio ativo, classe, tempo de tratamento, indicação clínica e reações adversas). Resultados: As classes terapêuticas mais prescritas foram os benzodiazepínicos, antipsicóticos e hipnóticos. Dentre os usos, 7,6% não tiveram justificativa clínica, e as demais justificativas incluíram conciliação medicamentosa, delirium hiperativo, desmame de sedação e insônia como as mais frequentes. Reações adversas como rebaixamento de nível de consciência, sonolência diurna, constipação, confusão mental, e outras foram observadas. Os resultados obtidos estão de acordo com os resultados esperados no que se refere à possibilidade de contribuição para discussão sobre o panorama atual do uso de medicamentos potencialmente inapropriados a idosos em Unidades de Terapia Intensiva e possíveis perspectivas e alternativas terapêuticas. Conclusão: É importante ressaltar a importância do monitoramento do uso destes medicamentos quando seu uso for inevitável, bem como evitar ou reduzir sua prescrição, associando outras terapias com menor risco, tendo em vista os potenciais efeitos nocivos dos medicamentos inapropriados.Research, Society and Development2022-06-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3074910.33448/rsd-v11i8.30749Research, Society and Development; Vol. 11 No. 8; e22211830749Research, Society and Development; Vol. 11 Núm. 8; e22211830749Research, Society and Development; v. 11 n. 8; e222118307492525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/30749/26436Copyright (c) 2022 Anna Carolinne Santana Neves; Alan Lucena de Vasconcelos; Maria do Carmo Lencastre de Menezes e Cruz Dueire Lins; Victor Avelino de Almeida; Aurylanne Mikaelle Brandão Silvahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessNeves, Anna Carolinne Santana Vasconcelos, Alan Lucena de Lins, Maria do Carmo Lencastre de Menezes e Cruz DueireAlmeida, Victor Avelino de Silva, Aurylanne Mikaelle Brandão 2022-07-01T13:34:06Zoai:ojs.pkp.sfu.ca:article/30749Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:47:24.038010Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Analysis of the use of potentially inappropriate medication in elderly hospitalized in an Intensive Care Unit in a large hospital in Recife
Análisis del uso de medicación potencialmente inapropiada en ancianos hospitalizados en una Unidad De Cuidados Intensivos en un gran hospital de Recife
Análise do uso de medicamentos potencialmente inapropriados em idosos internados em Unidade de Terapia Intensiva em um hospital de grande porte em Recife
title Analysis of the use of potentially inappropriate medication in elderly hospitalized in an Intensive Care Unit in a large hospital in Recife
spellingShingle Analysis of the use of potentially inappropriate medication in elderly hospitalized in an Intensive Care Unit in a large hospital in Recife
Neves, Anna Carolinne Santana
Critérios de Beers
Geriatria
Gerontologia
Prescrição
Unidade de Terapia Intensiva.
Beers Criteria
Geriatrics
Gerontology
Prescription
Intensive Care Unit.
Criterios de Beers
Geriatria
Gerontologia
Prescripción
Unidad de Cuidados Intensivos.
title_short Analysis of the use of potentially inappropriate medication in elderly hospitalized in an Intensive Care Unit in a large hospital in Recife
title_full Analysis of the use of potentially inappropriate medication in elderly hospitalized in an Intensive Care Unit in a large hospital in Recife
title_fullStr Analysis of the use of potentially inappropriate medication in elderly hospitalized in an Intensive Care Unit in a large hospital in Recife
title_full_unstemmed Analysis of the use of potentially inappropriate medication in elderly hospitalized in an Intensive Care Unit in a large hospital in Recife
title_sort Analysis of the use of potentially inappropriate medication in elderly hospitalized in an Intensive Care Unit in a large hospital in Recife
author Neves, Anna Carolinne Santana
author_facet Neves, Anna Carolinne Santana
Vasconcelos, Alan Lucena de
Lins, Maria do Carmo Lencastre de Menezes e Cruz Dueire
Almeida, Victor Avelino de
Silva, Aurylanne Mikaelle Brandão
author_role author
author2 Vasconcelos, Alan Lucena de
Lins, Maria do Carmo Lencastre de Menezes e Cruz Dueire
Almeida, Victor Avelino de
Silva, Aurylanne Mikaelle Brandão
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Neves, Anna Carolinne Santana
Vasconcelos, Alan Lucena de
Lins, Maria do Carmo Lencastre de Menezes e Cruz Dueire
Almeida, Victor Avelino de
Silva, Aurylanne Mikaelle Brandão
dc.subject.por.fl_str_mv Critérios de Beers
Geriatria
Gerontologia
Prescrição
Unidade de Terapia Intensiva.
Beers Criteria
Geriatrics
Gerontology
Prescription
Intensive Care Unit.
Criterios de Beers
Geriatria
Gerontologia
Prescripción
Unidad de Cuidados Intensivos.
topic Critérios de Beers
Geriatria
Gerontologia
Prescrição
Unidade de Terapia Intensiva.
Beers Criteria
Geriatrics
Gerontology
Prescription
Intensive Care Unit.
Criterios de Beers
Geriatria
Gerontologia
Prescripción
Unidad de Cuidados Intensivos.
description Aim: To analyze the use of potentially inappropriate drugs prescribed to the elderly in Intensive Care Units. Methodology: Observational, descriptive, cross-sectional and retrospective study. The study was carried out by analyzing the electronic medical records of patients over 60 years of age, using potentially inappropriate drugs in the elderly with action on the central nervous system. Clinical and sociodemographic data were collected, as well as data regarding the use of these drugs (active pharmaceutical ingredient, drug class, treatment time, clinical indication and adverse reactions). Results: The most prescribed therapeutic classes were benzodiazepines, antipsychotics and hypnotics. Among the uses, 7.6% had no clinical justification, and the other justifications included medication reconciliation, hyperactive delirium, weaning from sedation and insomnia as the most frequent. Adverse reactions such as lowered level of consciousness, daytime sleepiness, constipation, mental confusion, and others have been observed. The results obtained are in agreement with the expected results regarding the possibility of contributing to the discussion on the current scenario of the use of potentially inappropriate drugs for the elderly in Intensive Care Units and possible perspectives and therapeutic alternatives. Conclusion: It is important to emphasize the importance of monitoring the use of these drugs when their use is unavoidable, as well as avoiding or reducing their prescription, associating other therapies with lower risk, in view of the potential harmful effects of inappropriate drugs.
publishDate 2022
dc.date.none.fl_str_mv 2022-06-16
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/30749
10.33448/rsd-v11i8.30749
url https://rsdjournal.org/index.php/rsd/article/view/30749
identifier_str_mv 10.33448/rsd-v11i8.30749
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/30749/26436
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 8; e22211830749
Research, Society and Development; Vol. 11 Núm. 8; e22211830749
Research, Society and Development; v. 11 n. 8; e22211830749
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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