Bioactive potential of finches: Effect of the aqueous extract of leaves of Phoradendron piperoides (Kunt.) Trel. (Santalaceae) on mitosis

Detalhes bibliográficos
Autor(a) principal: Rieder , Arno
Data de Publicação: 2021
Outros Autores: Rodrigues , Fabiana Aparecida Caldart, Santos, Maria das Dores dos, Pegaiani, Kauanne Naysa Alves, Abreu, Edir de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/17070
Resumo: Medicinal mistletoes are also used in cancer therapies. Mitotic effects of the aqueous leaf extract of Phoradendron piperoides (Kunth) Trel. were evaluated. The plant material was collected in Cáceres, Mato Grosso, Brazil, in 2017. The test with three concentrations of aqueous leaf extract (0, 6 and 18 g of leaf powder/500 mL of water) was applied to Allium cepa L. Newly-emitted onion roots were immersed in the solution for 24 hours (action) and another 24 hours in water (recovery). Roots were collected for microscopy and cell counting was used to calculate the mitotic indices (MI%), which showed a lower value at the highest concentration than the intermediate concentration (3.95% c < 16.80% b), both differing from the control (60.40% a). Mitosis inhibition increased with an increase in extract concentration. The mitotic indices in the control of action and recovery tests were similar (60.47%) but higher than in the other concentrations. The indices were higher (3.95% B < 46.00% A) at intermediate doses (16.80% B < 36.60% A) and lower (p < 0.05) in the action than the recovery considering the overall average (27.05% B < 47.71% A). Thus, P. piperoides has bioactive compounds extracted in water that are inhibitors of mitosis, dose-dependent, and partially reversible effects on recovery.
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spelling Bioactive potential of finches: Effect of the aqueous extract of leaves of Phoradendron piperoides (Kunt.) Trel. (Santalaceae) on mitosisPotencial bioactivo de los pinzones: Efecto del extracto acuoso de hojas de Phoradendron piperoides (Kunt.) Trel. (Santalaceae) sobre la mitosis Potencial bioativo de ervas-de-passarinho: Efeito do extrato aquoso de folhas de Phoradendron piperoides (Kunt.) Trel. (Santalaceae) na mitoseExtratosUso popularBioatividadeAlterações na mitoseCitotóxicoRecuperação.ExtractosUso popularBioactividadCambios en la mitosisCitotóxicoRecuperación. ExtractsFolk useBioactivityChanges in mitosisCytotoxicRecovery.Medicinal mistletoes are also used in cancer therapies. Mitotic effects of the aqueous leaf extract of Phoradendron piperoides (Kunth) Trel. were evaluated. The plant material was collected in Cáceres, Mato Grosso, Brazil, in 2017. The test with three concentrations of aqueous leaf extract (0, 6 and 18 g of leaf powder/500 mL of water) was applied to Allium cepa L. Newly-emitted onion roots were immersed in the solution for 24 hours (action) and another 24 hours in water (recovery). Roots were collected for microscopy and cell counting was used to calculate the mitotic indices (MI%), which showed a lower value at the highest concentration than the intermediate concentration (3.95% c < 16.80% b), both differing from the control (60.40% a). Mitosis inhibition increased with an increase in extract concentration. The mitotic indices in the control of action and recovery tests were similar (60.47%) but higher than in the other concentrations. The indices were higher (3.95% B < 46.00% A) at intermediate doses (16.80% B < 36.60% A) and lower (p < 0.05) in the action than the recovery considering the overall average (27.05% B < 47.71% A). Thus, P. piperoides has bioactive compounds extracted in water that are inhibitors of mitosis, dose-dependent, and partially reversible effects on recovery.Las hierbas medicinales para aves también se utilizan en terapias contra el cáncer. Se evaluaron los efectos mitóticos del extracto acuoso de hojas de Phoradendron piperoides (Kunth) Trel. El material vegetal fue recolectado en Cáceres, Mato Grosso, Brasil, 2017. Se aplicó la prueba de Allium cepa L. con tres concentraciones de extracto acuoso de hoja (0, 6 y 18 g de polvo de hoja / 500 mL de agua). Las cebollas con raíces recién emitidas se sumergieron en la solución durante 24 horas (acción) y durante otras 24 horas en agua (recuperación). Se recolectaron raíces para microscopía y recuento celular para calcular índices mitóticos (% IM). Este, en la concentración más alta, fue menor que en el intermedio (3,95% c <16,80% b) y ambos fueron diferentes del control (60,40% a). La inhibición de la mitosis se acentuó con el aumento de la concentración del extracto. Los índices mitóticos, en el control de la acción y las pruebas de recuperación fueron similares (60,47%), pero superiores a las demás concentraciones; en las dosis intermedias (16.80% B < 36,60% A), superiores (3,95% B <46,00% A) y en la media general (27,05% B < 47,71% A) fueron menores (p < 0,05) en la acción que en la recuperación. Se concluye que P. piperoides tiene compuestos bioactivos, extraídos en agua, inhibidores de la mitosis, efectos dosis-dependientes y parcialmente reversibles en recuperación. Ervas-de-passarinho medicinais são utilizadas também em câncer-terapias. Nesse trabalho avaliaram-se efeitos mitóticos do extrato aquoso de folhas do Phoradendron piperoides (Kunth) Trel.. O material vegetal foi coletado em Cáceres, Mato Grosso, Brasil, 2017. Aplicou-se o teste Allium cepa com três concentrações de extrato aquoso foliar (0, 6 e 18 g do pó de folhas/500 mL de água). As cebolas com raízes recém-emitidas ficaram imersas, na solução, por 24 horas (ação) e, por mais 24 horas em água (recuperação). Foram coletadas raízes para microscopia e contagem de células para cálculo dos índices mitóticos (IM%). O IM% na maior concentração foi menor que na intermediária (3,95% c < 16,80% b) e, estas duas, distinguiram-se do controle (60,40% a). A inibição da mitose acentuou-se com o aumento da concentração do extrato. Os IM%, no controle dos ensaios de ação e de recuperação estiveram similares (60,47%), mas maiores que nas demais concentrações; nas doses intermediária (16,80% B < 36,60% A), maior (3,95% B < 46,00% A) e na média geral (27,05% B < 47,71% A) foram menores (p < 0,05) na ação que na recuperação. Por fim evidencia-se que P. piperoides possui compostos bioativos, extraídos em água, inibidores da mitose, efeitos dose-dependente e parcialmente reversíveis na recuperação. Research, Society and Development2021-07-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1707010.33448/rsd-v10i8.17070Research, Society and Development; Vol. 10 No. 8; e8310817070Research, Society and Development; Vol. 10 Núm. 8; e8310817070Research, Society and Development; v. 10 n. 8; e83108170702525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/17070/15228Copyright (c) 2021 Arno Rieder ; Fabiana Aparecida Caldart Rodrigues ; Maria das Dores dos Santos; Kauanne Naysa Alves Pegaiani; Edir de Abreuhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRieder , Arno Rodrigues , Fabiana Aparecida Caldart Santos, Maria das Dores dos Pegaiani, Kauanne Naysa Alves Abreu, Edir de 2021-08-21T18:46:59Zoai:ojs.pkp.sfu.ca:article/17070Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:37:28.906900Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Bioactive potential of finches: Effect of the aqueous extract of leaves of Phoradendron piperoides (Kunt.) Trel. (Santalaceae) on mitosis
Potencial bioactivo de los pinzones: Efecto del extracto acuoso de hojas de Phoradendron piperoides (Kunt.) Trel. (Santalaceae) sobre la mitosis
Potencial bioativo de ervas-de-passarinho: Efeito do extrato aquoso de folhas de Phoradendron piperoides (Kunt.) Trel. (Santalaceae) na mitose
title Bioactive potential of finches: Effect of the aqueous extract of leaves of Phoradendron piperoides (Kunt.) Trel. (Santalaceae) on mitosis
spellingShingle Bioactive potential of finches: Effect of the aqueous extract of leaves of Phoradendron piperoides (Kunt.) Trel. (Santalaceae) on mitosis
Rieder , Arno
Extratos
Uso popular
Bioatividade
Alterações na mitose
Citotóxico
Recuperação.
Extractos
Uso popular
Bioactividad
Cambios en la mitosis
Citotóxico
Recuperación.
Extracts
Folk use
Bioactivity
Changes in mitosis
Cytotoxic
Recovery.
title_short Bioactive potential of finches: Effect of the aqueous extract of leaves of Phoradendron piperoides (Kunt.) Trel. (Santalaceae) on mitosis
title_full Bioactive potential of finches: Effect of the aqueous extract of leaves of Phoradendron piperoides (Kunt.) Trel. (Santalaceae) on mitosis
title_fullStr Bioactive potential of finches: Effect of the aqueous extract of leaves of Phoradendron piperoides (Kunt.) Trel. (Santalaceae) on mitosis
title_full_unstemmed Bioactive potential of finches: Effect of the aqueous extract of leaves of Phoradendron piperoides (Kunt.) Trel. (Santalaceae) on mitosis
title_sort Bioactive potential of finches: Effect of the aqueous extract of leaves of Phoradendron piperoides (Kunt.) Trel. (Santalaceae) on mitosis
author Rieder , Arno
author_facet Rieder , Arno
Rodrigues , Fabiana Aparecida Caldart
Santos, Maria das Dores dos
Pegaiani, Kauanne Naysa Alves
Abreu, Edir de
author_role author
author2 Rodrigues , Fabiana Aparecida Caldart
Santos, Maria das Dores dos
Pegaiani, Kauanne Naysa Alves
Abreu, Edir de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Rieder , Arno
Rodrigues , Fabiana Aparecida Caldart
Santos, Maria das Dores dos
Pegaiani, Kauanne Naysa Alves
Abreu, Edir de
dc.subject.por.fl_str_mv Extratos
Uso popular
Bioatividade
Alterações na mitose
Citotóxico
Recuperação.
Extractos
Uso popular
Bioactividad
Cambios en la mitosis
Citotóxico
Recuperación.
Extracts
Folk use
Bioactivity
Changes in mitosis
Cytotoxic
Recovery.
topic Extratos
Uso popular
Bioatividade
Alterações na mitose
Citotóxico
Recuperação.
Extractos
Uso popular
Bioactividad
Cambios en la mitosis
Citotóxico
Recuperación.
Extracts
Folk use
Bioactivity
Changes in mitosis
Cytotoxic
Recovery.
description Medicinal mistletoes are also used in cancer therapies. Mitotic effects of the aqueous leaf extract of Phoradendron piperoides (Kunth) Trel. were evaluated. The plant material was collected in Cáceres, Mato Grosso, Brazil, in 2017. The test with three concentrations of aqueous leaf extract (0, 6 and 18 g of leaf powder/500 mL of water) was applied to Allium cepa L. Newly-emitted onion roots were immersed in the solution for 24 hours (action) and another 24 hours in water (recovery). Roots were collected for microscopy and cell counting was used to calculate the mitotic indices (MI%), which showed a lower value at the highest concentration than the intermediate concentration (3.95% c < 16.80% b), both differing from the control (60.40% a). Mitosis inhibition increased with an increase in extract concentration. The mitotic indices in the control of action and recovery tests were similar (60.47%) but higher than in the other concentrations. The indices were higher (3.95% B < 46.00% A) at intermediate doses (16.80% B < 36.60% A) and lower (p < 0.05) in the action than the recovery considering the overall average (27.05% B < 47.71% A). Thus, P. piperoides has bioactive compounds extracted in water that are inhibitors of mitosis, dose-dependent, and partially reversible effects on recovery.
publishDate 2021
dc.date.none.fl_str_mv 2021-07-05
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/17070
10.33448/rsd-v10i8.17070
url https://rsdjournal.org/index.php/rsd/article/view/17070
identifier_str_mv 10.33448/rsd-v10i8.17070
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/17070/15228
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 8; e8310817070
Research, Society and Development; Vol. 10 Núm. 8; e8310817070
Research, Society and Development; v. 10 n. 8; e8310817070
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052641894727680

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