Unlicensed drugs: a discussion in pediatrics

Detalhes bibliográficos
Autor(a) principal: Barros, Débora Santos Lula
Data de Publicação: 2020
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/9262
Resumo: The scarcity of specific industrialized products for the pediatric public can impact the consumption of unlicensed drugs. Unlicensed drugs are those originating from licensed products, through modifications, in addition to imported ones, contraindicated ones and those that do not have information about the use in a certain group. This study aimed to investigate the prevalence of the use of unlicensed drugs, the drugs frequently prescribed in this context and the pharmaceutical forms of greatest production. In this sense, the methodology of integrative review of the scientific literature was used. The prevalence rates for the use of unlicensed medications ranged from 1.6 to 33.35%, demonstrating the diversity of the scenario according to the country studied. The drugs constantly prescribed were diuretics (furosemide, spironolactone and hydrochlorothiazide), folic acid, caffeine, phenobarbital and morphine. The pharmaceutical forms most frequently produced were liquid, with emphasis on solutions, suspensions and syrups. Although the pharmaceutical market has improved its productive capacity over time, the use of unlicensed drugs is still part of the pediatric care scenario in several countries.
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spelling Unlicensed drugs: a discussion in pediatricsMedicamentos no licenciados: una discusión en pediatríaMedicamentos não licenciados: uma discussão em pediatriaPreparações FarmacêuticasPediatriaFarmácia HospitalarAssistência FarmacêuticaUso de medicamentos.Pharmaceutical preparationsPediatricsHospital PharmacyPharmaceutical assistanceUse of medicines.Preparaciones farmacéuticasPediatríaFarmacia hospitalariaServicios FarmacéuticosUso de medicamentos.The scarcity of specific industrialized products for the pediatric public can impact the consumption of unlicensed drugs. Unlicensed drugs are those originating from licensed products, through modifications, in addition to imported ones, contraindicated ones and those that do not have information about the use in a certain group. This study aimed to investigate the prevalence of the use of unlicensed drugs, the drugs frequently prescribed in this context and the pharmaceutical forms of greatest production. In this sense, the methodology of integrative review of the scientific literature was used. The prevalence rates for the use of unlicensed medications ranged from 1.6 to 33.35%, demonstrating the diversity of the scenario according to the country studied. The drugs constantly prescribed were diuretics (furosemide, spironolactone and hydrochlorothiazide), folic acid, caffeine, phenobarbital and morphine. The pharmaceutical forms most frequently produced were liquid, with emphasis on solutions, suspensions and syrups. Although the pharmaceutical market has improved its productive capacity over time, the use of unlicensed drugs is still part of the pediatric care scenario in several countries.La escasez de productos industrializados específicos para el público pediátrico puede afectar el consumo de medicamentos sin licencia. Los medicamentos sin licencia son aquellos provenientes de productos licenciados, mediante modificaciones, además de los importados, contraindicados y los que no tienen información sobre el uso en un determinado grupo. Este estudio tuvo como objetivo investigar la prevalencia del uso de medicamentos sin licencia, los medicamentos frecuentemente prescritos en este contexto y las formas farmacéuticas de mayor producción. En este sentido, se utilizó la metodología de revisión integradora de la literatura científica. Las tasas de prevalencia para el uso de medicamentos sin licencia oscilaron entre 1,6 y 33,35%, lo que demuestra la diversidad del escenario según el país estudiado. Los fármacos prescritos constantemente fueron diuréticos (furosemida, espironolactona e hidroclorotiazida), ácido fólico, cafeína, fenobarbital y morfina. Las formas farmacéuticas producidas con mayor frecuencia fueron las líquidas, con énfasis en soluciones, suspensiones y jarabes. Si bien el mercado farmacéutico ha mejorado su capacidad productiva a lo largo del tiempo, el uso de medicamentos sin licencia sigue siendo parte del escenario de la atención pediátrica en varios países.A escassez de produtos industrializados específicos para o público pediátrico pode repercutir o consumo de medicamentos não licenciados. Os medicamentos não licenciados são aqueles originados a partir de produtos licenciados, por meio de modificações, além dos importados, os contraindicados e os que não possuem informações sobre o uso em determinado grupo. Esse estudo objetivou investigar a prevalência de uso de medicamentos não licenciados, os fármacos frequentemente prescritos nesse contexto e as formas farmacêuticas de maior produção. Nesse sentido, foi utilizada a metodologia de revisão integrativa da literatura científica. As taxas de prevalência de uso de medicamentos não licenciados variaram de 1,6 a 33,35%, demonstrando a diversidade do cenário conforme o país estudado. Os fármacos constantemente prescritos foram os diuréticos (furosemida, espironolactona e hidroclorotiazida), o ácido fólico, a cafeína, o fenobarbital e a morfina. As formas farmacêuticas produzidas com maior frequência foram as líquidas, com destaque para as soluções, as suspensões e os xaropes. Embora o mercado farmacêutico tenha aperfeiçoado a sua capacidade produtiva ao longo do tempo, o uso de medicamentos não licenciados ainda faz parte do cenário assistencial em pediatria em diversos países.Research, Society and Development2020-10-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/926210.33448/rsd-v9i10.9262Research, Society and Development; Vol. 9 No. 10; e8919109262Research, Society and Development; Vol. 9 Núm. 10; e8919109262Research, Society and Development; v. 9 n. 10; e89191092622525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/9262/8333Copyright (c) 2020 Débora Santos Lula Barroshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBarros, Débora Santos Lula 2020-10-31T12:03:23Zoai:ojs.pkp.sfu.ca:article/9262Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:31:35.433482Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Unlicensed drugs: a discussion in pediatrics
Medicamentos no licenciados: una discusión en pediatría
Medicamentos não licenciados: uma discussão em pediatria
title Unlicensed drugs: a discussion in pediatrics
spellingShingle Unlicensed drugs: a discussion in pediatrics
Barros, Débora Santos Lula
Preparações Farmacêuticas
Pediatria
Farmácia Hospitalar
Assistência Farmacêutica
Uso de medicamentos.
Pharmaceutical preparations
Pediatrics
Hospital Pharmacy
Pharmaceutical assistance
Use of medicines.
Preparaciones farmacéuticas
Pediatría
Farmacia hospitalaria
Servicios Farmacéuticos
Uso de medicamentos.
title_short Unlicensed drugs: a discussion in pediatrics
title_full Unlicensed drugs: a discussion in pediatrics
title_fullStr Unlicensed drugs: a discussion in pediatrics
title_full_unstemmed Unlicensed drugs: a discussion in pediatrics
title_sort Unlicensed drugs: a discussion in pediatrics
author Barros, Débora Santos Lula
author_facet Barros, Débora Santos Lula
author_role author
dc.contributor.author.fl_str_mv Barros, Débora Santos Lula
dc.subject.por.fl_str_mv Preparações Farmacêuticas
Pediatria
Farmácia Hospitalar
Assistência Farmacêutica
Uso de medicamentos.
Pharmaceutical preparations
Pediatrics
Hospital Pharmacy
Pharmaceutical assistance
Use of medicines.
Preparaciones farmacéuticas
Pediatría
Farmacia hospitalaria
Servicios Farmacéuticos
Uso de medicamentos.
topic Preparações Farmacêuticas
Pediatria
Farmácia Hospitalar
Assistência Farmacêutica
Uso de medicamentos.
Pharmaceutical preparations
Pediatrics
Hospital Pharmacy
Pharmaceutical assistance
Use of medicines.
Preparaciones farmacéuticas
Pediatría
Farmacia hospitalaria
Servicios Farmacéuticos
Uso de medicamentos.
description The scarcity of specific industrialized products for the pediatric public can impact the consumption of unlicensed drugs. Unlicensed drugs are those originating from licensed products, through modifications, in addition to imported ones, contraindicated ones and those that do not have information about the use in a certain group. This study aimed to investigate the prevalence of the use of unlicensed drugs, the drugs frequently prescribed in this context and the pharmaceutical forms of greatest production. In this sense, the methodology of integrative review of the scientific literature was used. The prevalence rates for the use of unlicensed medications ranged from 1.6 to 33.35%, demonstrating the diversity of the scenario according to the country studied. The drugs constantly prescribed were diuretics (furosemide, spironolactone and hydrochlorothiazide), folic acid, caffeine, phenobarbital and morphine. The pharmaceutical forms most frequently produced were liquid, with emphasis on solutions, suspensions and syrups. Although the pharmaceutical market has improved its productive capacity over time, the use of unlicensed drugs is still part of the pediatric care scenario in several countries.
publishDate 2020
dc.date.none.fl_str_mv 2020-10-24
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/9262
10.33448/rsd-v9i10.9262
url https://rsdjournal.org/index.php/rsd/article/view/9262
identifier_str_mv 10.33448/rsd-v9i10.9262
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/9262/8333
dc.rights.driver.fl_str_mv Copyright (c) 2020 Débora Santos Lula Barros
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Débora Santos Lula Barros
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 10; e8919109262
Research, Society and Development; Vol. 9 Núm. 10; e8919109262
Research, Society and Development; v. 9 n. 10; e8919109262
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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