Mimosa tenuiflora (Willd.) Poir and Anadenanthera colubrina as alternatives in drug addiction treatment
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/14251 |
Resumo: | Drug addiction is considered a worldwide public health problem. There are few effective pharmacotherapeutic options for this condition treatment. However, the use of serotonergic hallucinogenic molecules from plants used in religious contexts such as those found in Mimosa tenuiflora root bark and Anadenanthera colubrina seeds have great therapeutic potential by reducing addictive behaviors associated with abstinence. This paper presents the ethnopharmacological, phytochemical, pharmacological, and toxicological characteristics that can support the plants study Mimosa tenuiflora and Anadenanthera colubrina in drug addiction treatment. During this in narrative review, 159 texts were evaluated where it was possible to observe that there are justifications that can endorse the therapeutic investigation of these of these plants, especially when verifying the presence of serotoninergic hallucinogenic molecules such as N, N-dimetiltriptamine and 5-OH-N, N-dimetiltriptamine opening, therefore, the possibility of developing and producing new anti-addict therapeutic options. |
id |
UNIFEI_fed5d41072cac89e92afb4ea7c535b16 |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/14251 |
network_acronym_str |
UNIFEI |
network_name_str |
Research, Society and Development |
repository_id_str |
|
spelling |
Mimosa tenuiflora (Willd.) Poir and Anadenanthera colubrina as alternatives in drug addiction treatmentMimosa tenuiflora (Willd.) Poir y Anadenanthera colubrina como alternativas en el tratamiento de la adicción a las drogas Mimosa tenuiflora (Willd.) Poir e Anadenanthera colubrina como alternativas no tratamento da adicção às drogasNatural productsHallucinogensDrug abuse.Productos naturalesAlucinógenosAbuso de drogas.Produtos naturaisAlucinógenosAbuso de drogas.Dependência químicaDrug addiction is considered a worldwide public health problem. There are few effective pharmacotherapeutic options for this condition treatment. However, the use of serotonergic hallucinogenic molecules from plants used in religious contexts such as those found in Mimosa tenuiflora root bark and Anadenanthera colubrina seeds have great therapeutic potential by reducing addictive behaviors associated with abstinence. This paper presents the ethnopharmacological, phytochemical, pharmacological, and toxicological characteristics that can support the plants study Mimosa tenuiflora and Anadenanthera colubrina in drug addiction treatment. During this in narrative review, 159 texts were evaluated where it was possible to observe that there are justifications that can endorse the therapeutic investigation of these of these plants, especially when verifying the presence of serotoninergic hallucinogenic molecules such as N, N-dimetiltriptamine and 5-OH-N, N-dimetiltriptamine opening, therefore, the possibility of developing and producing new anti-addict therapeutic options.La adicción a las drogas se considera un problema global de salud pública. Hay pocas opciones farmacoterapéuticas eficaces para el tratamiento de esta afección. Sin embargo, el uso de moléculas alucinógenas serotonérgicas de plantas utilizadas en contextos religiosos como las que se encuentran en la corteza de la raíz de mimosa tenuiflora y em las semillas de Anadenanthera colubrina tienen un gran potencial terapéutico al reducir las conductas adictivas asociadas con la abstinencia. Este artículo presenta las características etnofarmacológicas, fitoquímicas, farmacológicas y toxicológicas que pueden apoyar el estudio de las plantas de Mimosa tenuiflora y Anadenanthera colubrina em el tratamiento de la adicción. En el transcurso de esta revisión narrativa se evaluaron 159 textos en los que se pudo observar que existen justificaciones que pueden avalar la investigación terapéutica de estas plantas, especialmente al verificar la presencia de moléculas alucinógenas serotonérgicas como N, N-dimetiltriptalina y 5-OH-N, N-dimetiltriptanina, que abren, por lo tanto, la posibilidad de desarrollar y producir nuevas opciones terapéuticas atiádicas.A adicção às drogas é considerada um problema de saúde pública a nível mundial. Há poucas opções farmacoterapêuticas eficazes para o tratamento desta condição. Contudo, o uso de moléculas alucinógenas serotoninérgicas provenientes de plantas utilizadas em contextos religiosos como as encontradas na casca da raiz da Mimosa tenuiflora e nas sementes da Anadenanthera colubrina possuem grande potencial terapêutico ao reduzir comportamentos adictivos associados à abstinência. Este artigo apresenta as características etnofarmacológicas, fitoquímicas, farmacológicas e toxicológicas que podem embasar o estudo das plantas Mimosa tenuiflora e Anadenanthera colubrina no tratamento da adicção às drogas. No decorrer desta revisão narrativa, foram avaliados 159 textos onde foi possível observar que existem justificativas que podem endossar a investigação terapêutica destas plantas, principalmente ao se verificar a presença de moléculas alucinógenas serotoninérgicas como a N, N-dimetiltriptamina e a 5-OH-N, N-dimetiltriptamina, abrindo, portanto, a possibilidade do desenvolvimento e produção de novas opções terapêuticas anti-adictivas.Research, Society and Development2021-04-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1425110.33448/rsd-v10i4.14251Research, Society and Development; Vol. 10 No. 4; e48710414251Research, Society and Development; Vol. 10 Núm. 4; e48710414251Research, Society and Development; v. 10 n. 4; e487104142512525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/14251/12915Copyright (c) 2021 Patrícia Caroline Machado de Sousa; Italo Nunes Arrais de Sousa; Lucas Luan Lima Leite; André Luiz Ozorio Oliveira; Karina Aparecida da Silva Souza; Jôslanne dos Santos Soares; Melquisedeque da Rocha Viana; Maurício Pires de Moura do Amaralhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSousa, Patrícia Caroline Machado de Sousa, Italo Nunes Arrais de Leite, Lucas Luan Lima Oliveira, André Luiz Ozorio Souza, Karina Aparecida da Silva Soares, Jôslanne dos Santos Viana, Melquisedeque da Rocha Amaral, Maurício Pires de Moura do 2021-04-25T11:21:26Zoai:ojs.pkp.sfu.ca:article/14251Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:35:25.192794Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Mimosa tenuiflora (Willd.) Poir and Anadenanthera colubrina as alternatives in drug addiction treatment Mimosa tenuiflora (Willd.) Poir y Anadenanthera colubrina como alternativas en el tratamiento de la adicción a las drogas Mimosa tenuiflora (Willd.) Poir e Anadenanthera colubrina como alternativas no tratamento da adicção às drogas |
title |
Mimosa tenuiflora (Willd.) Poir and Anadenanthera colubrina as alternatives in drug addiction treatment |
spellingShingle |
Mimosa tenuiflora (Willd.) Poir and Anadenanthera colubrina as alternatives in drug addiction treatment Sousa, Patrícia Caroline Machado de Natural products Hallucinogens Drug abuse. Productos naturales Alucinógenos Abuso de drogas. Produtos naturais Alucinógenos Abuso de drogas. Dependência química |
title_short |
Mimosa tenuiflora (Willd.) Poir and Anadenanthera colubrina as alternatives in drug addiction treatment |
title_full |
Mimosa tenuiflora (Willd.) Poir and Anadenanthera colubrina as alternatives in drug addiction treatment |
title_fullStr |
Mimosa tenuiflora (Willd.) Poir and Anadenanthera colubrina as alternatives in drug addiction treatment |
title_full_unstemmed |
Mimosa tenuiflora (Willd.) Poir and Anadenanthera colubrina as alternatives in drug addiction treatment |
title_sort |
Mimosa tenuiflora (Willd.) Poir and Anadenanthera colubrina as alternatives in drug addiction treatment |
author |
Sousa, Patrícia Caroline Machado de |
author_facet |
Sousa, Patrícia Caroline Machado de Sousa, Italo Nunes Arrais de Leite, Lucas Luan Lima Oliveira, André Luiz Ozorio Souza, Karina Aparecida da Silva Soares, Jôslanne dos Santos Viana, Melquisedeque da Rocha Amaral, Maurício Pires de Moura do |
author_role |
author |
author2 |
Sousa, Italo Nunes Arrais de Leite, Lucas Luan Lima Oliveira, André Luiz Ozorio Souza, Karina Aparecida da Silva Soares, Jôslanne dos Santos Viana, Melquisedeque da Rocha Amaral, Maurício Pires de Moura do |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Sousa, Patrícia Caroline Machado de Sousa, Italo Nunes Arrais de Leite, Lucas Luan Lima Oliveira, André Luiz Ozorio Souza, Karina Aparecida da Silva Soares, Jôslanne dos Santos Viana, Melquisedeque da Rocha Amaral, Maurício Pires de Moura do |
dc.subject.por.fl_str_mv |
Natural products Hallucinogens Drug abuse. Productos naturales Alucinógenos Abuso de drogas. Produtos naturais Alucinógenos Abuso de drogas. Dependência química |
topic |
Natural products Hallucinogens Drug abuse. Productos naturales Alucinógenos Abuso de drogas. Produtos naturais Alucinógenos Abuso de drogas. Dependência química |
description |
Drug addiction is considered a worldwide public health problem. There are few effective pharmacotherapeutic options for this condition treatment. However, the use of serotonergic hallucinogenic molecules from plants used in religious contexts such as those found in Mimosa tenuiflora root bark and Anadenanthera colubrina seeds have great therapeutic potential by reducing addictive behaviors associated with abstinence. This paper presents the ethnopharmacological, phytochemical, pharmacological, and toxicological characteristics that can support the plants study Mimosa tenuiflora and Anadenanthera colubrina in drug addiction treatment. During this in narrative review, 159 texts were evaluated where it was possible to observe that there are justifications that can endorse the therapeutic investigation of these of these plants, especially when verifying the presence of serotoninergic hallucinogenic molecules such as N, N-dimetiltriptamine and 5-OH-N, N-dimetiltriptamine opening, therefore, the possibility of developing and producing new anti-addict therapeutic options. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-04-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/14251 10.33448/rsd-v10i4.14251 |
url |
https://rsdjournal.org/index.php/rsd/article/view/14251 |
identifier_str_mv |
10.33448/rsd-v10i4.14251 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/14251/12915 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 4; e48710414251 Research, Society and Development; Vol. 10 Núm. 4; e48710414251 Research, Society and Development; v. 10 n. 4; e48710414251 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
_version_ |
1797052747886886912 |