Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg)

Detalhes bibliográficos
Autor(a) principal: Coelho, Jéssica Aparecida
Data de Publicação: 2017
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações do UNIOESTE
Texto Completo: http://tede.unioeste.br/handle/tede/2959
Resumo: Currently, research related to natural products, mainly those of plant origin, has been strongly encouraged by the World Health Organization (WHO), once the use of plants with proven or unproven medicinal properties are of great influence on public health. Among the high medicinal potential plants, the species Myrciaria cauliflora Berg, which belongs to the Myrtaceae family, popularly known as `Jabuticaba`, a typical Brazilian fruit, is used in popular medicine to treat angina pectoris, dysentery, inflammation and asthma. Aiming to highlight the importance of the use of plants for the treatment of various diseases, the aim of this work was to identify the bioactive compounds present in Jabuticaba peel, and to perform in vitro tests of antioxidant action, antimicrobial potential and cytotoxic effect against red blood cells. The tests were carried out with the aim of obtaining results that could prove the possible pharmacological activities of the organic extracts, for further development of formulation with the use of pharmaceutical technology. Bioprospecting studies from the Brazilian flora represent concrete possibilities in the discovery of new antimicrobial agents, as well as the improvement and the discovery of new technologies in the most diverse industrial branches, with emphasis in the health sector.
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spelling Rosa, Mauricio Ferreira dahttp://lattes.cnpq.br/3207812515849010Prochnau, Inara Staubhttp://lattes.cnpq.br/4022625544167684Rosa, Mauricio Ferreira dahttp://lattes.cnpq.br/3207812515849010Hoscheid, Jaquelinehttp://lattes.cnpq.br/3955331600809048Manarin, Flávia Giovanahttp://lattes.cnpq.br/9369626756137666http://lattes.cnpq.br/2887407079485007Coelho, Jéssica Aparecida2017-08-30T17:15:03Z2017-02-08COELHO, Jéssica Aparecida. Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg). 2017. 56 f. Dissertação(Mestrado em Ciências Farmacêuticas) - Universidade Estadual do Oeste do Paraná, Cascavel, 2017 .http://tede.unioeste.br/handle/tede/2959Currently, research related to natural products, mainly those of plant origin, has been strongly encouraged by the World Health Organization (WHO), once the use of plants with proven or unproven medicinal properties are of great influence on public health. Among the high medicinal potential plants, the species Myrciaria cauliflora Berg, which belongs to the Myrtaceae family, popularly known as `Jabuticaba`, a typical Brazilian fruit, is used in popular medicine to treat angina pectoris, dysentery, inflammation and asthma. Aiming to highlight the importance of the use of plants for the treatment of various diseases, the aim of this work was to identify the bioactive compounds present in Jabuticaba peel, and to perform in vitro tests of antioxidant action, antimicrobial potential and cytotoxic effect against red blood cells. The tests were carried out with the aim of obtaining results that could prove the possible pharmacological activities of the organic extracts, for further development of formulation with the use of pharmaceutical technology. Bioprospecting studies from the Brazilian flora represent concrete possibilities in the discovery of new antimicrobial agents, as well as the improvement and the discovery of new technologies in the most diverse industrial branches, with emphasis in the health sector.Atualmente as pesquisas relacionadas aos produtos naturais, principalmente os de origem vegetal, têm sido incentivadas fortemente pela Organização Mundial da Saúde (OMS), visto que o uso de plantas com propriedades medicinais, comprovadas ou não, são de grande influência na saúde pública. Dentre as plantas com um alto potencial medicinal, destaca-se a espécie vegetal Myrciaria cauliflora Berg, pertencente à família Myrtaceae, conhecida popularmente como jabuticaba, fruta tipicamente brasileira, utilizada na medicina popular para tratar anginas do peito, disenterias, inflamações e asma. Visando ressaltar a importância do uso de plantas para o tratamento de diversos males, o intuito desse trabalho foi realizar a identificação dos compostos bioativos presentes nas cascas da jabuticaba, além, de realizar testes in vitro de ação antioxidante, potencial antimicrobiano e efeito citotóxico frente a hemácias humanas. Os testes foram realizados com o intuito de obter resultados que comprovassem as possíveis atividades farmacológicas dos extratos orgânicos, para posterior desenvolvimento de formulação com o uso de tecnologia farmacêutica. Estudos de bioprospecção a partir da flora brasileira, representam possibilidades concretas na descoberta de novos agentes antimicrobianos, assim como o aprimoramente e descobrimento de novas tecnologias nos mais diversos ramos industriais, com ênfase no setor da saúde.Submitted by Rosangela Silva (rosangela.silva3@unioeste.br) on 2017-08-30T17:15:03Z No. of bitstreams: 2 Jéssica Aparecida Coelho.pdf: 983869 bytes, checksum: f052f02c58568ed9e5417fa5e8c7bc58 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Made available in DSpace on 2017-08-30T17:15:03Z (GMT). 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dc.title.por.fl_str_mv Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg)
dc.title.alternative.eng.fl_str_mv In vitro evaluation of antioxidant, antimicrobial and cytotoxic activities from organic extracts of the jabuticaba fruit’s peel (Myrciaria cauliflora Berg)
title Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg)
spellingShingle Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg)
Coelho, Jéssica Aparecida
Extratos vegetais
Plantas medicinais
Atividade antioxidante
Plant extracts
Medicinal plants
Antioxidant activity
CIENCIAS DA SAUDE::FARMACIA
title_short Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg)
title_full Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg)
title_fullStr Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg)
title_full_unstemmed Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg)
title_sort Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg)
author Coelho, Jéssica Aparecida
author_facet Coelho, Jéssica Aparecida
author_role author
dc.contributor.advisor1.fl_str_mv Rosa, Mauricio Ferreira da
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/3207812515849010
dc.contributor.advisor-co1.fl_str_mv Prochnau, Inara Staub
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/4022625544167684
dc.contributor.referee1.fl_str_mv Rosa, Mauricio Ferreira da
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/3207812515849010
dc.contributor.referee2.fl_str_mv Hoscheid, Jaqueline
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/3955331600809048
dc.contributor.referee3.fl_str_mv Manarin, Flávia Giovana
dc.contributor.referee3Lattes.fl_str_mv http://lattes.cnpq.br/9369626756137666
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/2887407079485007
dc.contributor.author.fl_str_mv Coelho, Jéssica Aparecida
contributor_str_mv Rosa, Mauricio Ferreira da
Prochnau, Inara Staub
Rosa, Mauricio Ferreira da
Hoscheid, Jaqueline
Manarin, Flávia Giovana
dc.subject.por.fl_str_mv Extratos vegetais
Plantas medicinais
Atividade antioxidante
topic Extratos vegetais
Plantas medicinais
Atividade antioxidante
Plant extracts
Medicinal plants
Antioxidant activity
CIENCIAS DA SAUDE::FARMACIA
dc.subject.eng.fl_str_mv Plant extracts
Medicinal plants
Antioxidant activity
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::FARMACIA
description Currently, research related to natural products, mainly those of plant origin, has been strongly encouraged by the World Health Organization (WHO), once the use of plants with proven or unproven medicinal properties are of great influence on public health. Among the high medicinal potential plants, the species Myrciaria cauliflora Berg, which belongs to the Myrtaceae family, popularly known as `Jabuticaba`, a typical Brazilian fruit, is used in popular medicine to treat angina pectoris, dysentery, inflammation and asthma. Aiming to highlight the importance of the use of plants for the treatment of various diseases, the aim of this work was to identify the bioactive compounds present in Jabuticaba peel, and to perform in vitro tests of antioxidant action, antimicrobial potential and cytotoxic effect against red blood cells. The tests were carried out with the aim of obtaining results that could prove the possible pharmacological activities of the organic extracts, for further development of formulation with the use of pharmaceutical technology. Bioprospecting studies from the Brazilian flora represent concrete possibilities in the discovery of new antimicrobial agents, as well as the improvement and the discovery of new technologies in the most diverse industrial branches, with emphasis in the health sector.
publishDate 2017
dc.date.accessioned.fl_str_mv 2017-08-30T17:15:03Z
dc.date.issued.fl_str_mv 2017-02-08
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dc.identifier.citation.fl_str_mv COELHO, Jéssica Aparecida. Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg). 2017. 56 f. Dissertação(Mestrado em Ciências Farmacêuticas) - Universidade Estadual do Oeste do Paraná, Cascavel, 2017 .
dc.identifier.uri.fl_str_mv http://tede.unioeste.br/handle/tede/2959
identifier_str_mv COELHO, Jéssica Aparecida. Avaliação in vitro das atividades antioxidante, antimicrobiana e citotóxica de extratos orgânicos das cascas da do fruto jabuticaba (Myrciaria cauliflora Berg). 2017. 56 f. Dissertação(Mestrado em Ciências Farmacêuticas) - Universidade Estadual do Oeste do Paraná, Cascavel, 2017 .
url http://tede.unioeste.br/handle/tede/2959
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Cascavel
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dc.publisher.initials.fl_str_mv UNIOESTE
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dc.publisher.department.fl_str_mv Centro de Ciências Médicas e Farmacêuticas
publisher.none.fl_str_mv Universidade Estadual do Oeste do Paraná
Cascavel
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