POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTES

Detalhes bibliográficos
Autor(a) principal: Magalhães, Alan José Barbosa
Data de Publicação: 2020
Outros Autores: Modolo Regueiro Lorençoni, Roselene
Tipo de documento: Artigo
Idioma: por
Título da fonte: Colloquium Vitae
Texto Completo: http://revistas.unoeste.br/index.php/cv/article/view/3312
Resumo: The aim of this study was to analyze the effects of diet’s potassium dichromate supplementation on cardiac muscle tissue morphology in rats. Forty male rats were used, divided into G0: basal diet, G1: basal diet + 12 mg.kg-1 potassium dichromate, G2: basal diet + 24 mg.kg-1 and G3: basal diet + 36 mg.kg -1 for 90 days. The animals were euthanized, with heart extraction for morphological analysis and fractal dimension analysis. Anova One-Way, Kruskall-Wallis, Tukey and Dunn were used to compare the results, with p<0.05. There is no differences on body mass and heart mass. G1 showed greater tissue inflammation of compared to G2 and G0. It was concluded that potassium dichromate generates morphological changes by proinflammatory effect in rat cardiomyocytes.
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spelling POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTESINGESTÃO DE DICROMATO DE POTÁSSIO INDUZ ALTERAÇÕES MORFOLÓGICAS EM CARDIOMIÓCITOS DE RATOSThe aim of this study was to analyze the effects of diet’s potassium dichromate supplementation on cardiac muscle tissue morphology in rats. Forty male rats were used, divided into G0: basal diet, G1: basal diet + 12 mg.kg-1 potassium dichromate, G2: basal diet + 24 mg.kg-1 and G3: basal diet + 36 mg.kg -1 for 90 days. The animals were euthanized, with heart extraction for morphological analysis and fractal dimension analysis. Anova One-Way, Kruskall-Wallis, Tukey and Dunn were used to compare the results, with p<0.05. There is no differences on body mass and heart mass. G1 showed greater tissue inflammation of compared to G2 and G0. It was concluded that potassium dichromate generates morphological changes by proinflammatory effect in rat cardiomyocytes.O objetivo do estudo foi analisar efeitos da suplementação de dicromato de potássio à dieta sobre a morfologia do tecido muscular cardíaco de ratos. Foram utilizados 40 ratos machos, divididos em G0: dieta basal, G1: dieta basal + 12 mg.kg-1 de dicromato de potássio, G2: dieta basal + 24 mg.kg-1 e G3: dieta basal + 36 mg.kg-1, por 90 dias. Os animais foram eutanasiados, com extração do coração para análises morfológicas e análise da dimensão fractal. Foram utilizados o teste de Levene, Anova One-Way, Kruskall-Wallis, Tukey e Dunn para comparação dos resultados, adotando p<0,05. Não houve diferenças na massa corporal e massa do coração. G1 apresentou maior inflamação tecidual em relação a G2 e G0. Conclui-se que o dicromato de potássio pode gerar alterações morfológicas em decorrência de efeito pró-inflamatório em cardiomiócitos de ratos.Universidade do Oeste Paulista - UNOESTE2020-02-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por paresapplication/pdfhttp://revistas.unoeste.br/index.php/cv/article/view/3312Colloquium Vitae. ISSN: 1984-6436; v. 12 n. 1 (2020): Colloquium Vitae, Vol. 12, n. 1; 29-371984-6436reponame:Colloquium Vitaeinstname:Universidade do Oeste Paulista (UNOESTE)instacron:UNIOESTEporhttp://revistas.unoeste.br/index.php/cv/article/view/3312/2952Copyright (c) 2020 Colloquium Vitae. ISSN: 1984-6436info:eu-repo/semantics/openAccessMagalhães, Alan José BarbosaModolo Regueiro Lorençoni, Roselene 2020-06-29T18:42:31Zoai:ojs.pkp.sfu.ca:article/3312Revistahttps://revistas.unoeste.br/index.php/cv/indexONGhttp://revistas.unoeste.br/revistas/ojs/index.php/cv/oaijgjunior@unoeste.br||jgjunior@unoeste.br1984-64361984-6436opendoar:2020-06-29T18:42:31Colloquium Vitae - Universidade do Oeste Paulista (UNOESTE)false
dc.title.none.fl_str_mv POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTES
INGESTÃO DE DICROMATO DE POTÁSSIO INDUZ ALTERAÇÕES MORFOLÓGICAS EM CARDIOMIÓCITOS DE RATOS
title POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTES
spellingShingle POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTES
Magalhães, Alan José Barbosa
title_short POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTES
title_full POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTES
title_fullStr POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTES
title_full_unstemmed POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTES
title_sort POTASSIUM DICHROMATE INTAKE INDUCES MORPHOLOGICAL CHANGES IN RAT’S CARDIOMYOCYTES
author Magalhães, Alan José Barbosa
author_facet Magalhães, Alan José Barbosa
Modolo Regueiro Lorençoni, Roselene
author_role author
author2 Modolo Regueiro Lorençoni, Roselene
author2_role author
dc.contributor.author.fl_str_mv Magalhães, Alan José Barbosa
Modolo Regueiro Lorençoni, Roselene
description The aim of this study was to analyze the effects of diet’s potassium dichromate supplementation on cardiac muscle tissue morphology in rats. Forty male rats were used, divided into G0: basal diet, G1: basal diet + 12 mg.kg-1 potassium dichromate, G2: basal diet + 24 mg.kg-1 and G3: basal diet + 36 mg.kg -1 for 90 days. The animals were euthanized, with heart extraction for morphological analysis and fractal dimension analysis. Anova One-Way, Kruskall-Wallis, Tukey and Dunn were used to compare the results, with p<0.05. There is no differences on body mass and heart mass. G1 showed greater tissue inflammation of compared to G2 and G0. It was concluded that potassium dichromate generates morphological changes by proinflammatory effect in rat cardiomyocytes.
publishDate 2020
dc.date.none.fl_str_mv 2020-02-18
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado por pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://revistas.unoeste.br/index.php/cv/article/view/3312
url http://revistas.unoeste.br/index.php/cv/article/view/3312
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv http://revistas.unoeste.br/index.php/cv/article/view/3312/2952
dc.rights.driver.fl_str_mv Copyright (c) 2020 Colloquium Vitae. ISSN: 1984-6436
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Colloquium Vitae. ISSN: 1984-6436
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade do Oeste Paulista - UNOESTE
publisher.none.fl_str_mv Universidade do Oeste Paulista - UNOESTE
dc.source.none.fl_str_mv Colloquium Vitae. ISSN: 1984-6436; v. 12 n. 1 (2020): Colloquium Vitae, Vol. 12, n. 1; 29-37
1984-6436
reponame:Colloquium Vitae
instname:Universidade do Oeste Paulista (UNOESTE)
instacron:UNIOESTE
instname_str Universidade do Oeste Paulista (UNOESTE)
instacron_str UNIOESTE
institution UNIOESTE
reponame_str Colloquium Vitae
collection Colloquium Vitae
repository.name.fl_str_mv Colloquium Vitae - Universidade do Oeste Paulista (UNOESTE)
repository.mail.fl_str_mv jgjunior@unoeste.br||jgjunior@unoeste.br
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