Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental study
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2020 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Colloquium Vitae |
| Texto Completo: | http://revistas.unoeste.br/index.php/cv/article/view/3266 |
Resumo: | The purpose of study was to evaluate the behavioral changes of male and female adult rats exposed to fine and ultrafine particulate matter (PM≤2,5) suspended in air pollution during development. Wistar rats aged 7 days postnatal were exposed to the chamber of an atmospheric particle concentrator. Open field tests and sucrose preference tests were performed to assess the presence of anxiety and depression behaviors. Male rats from the pollution group showed reduced locomotor activity and length of stay in the open field center when compared to the control group males. The sucrose preference test showed statistical significance between the pollution and control groups, and among the males of the pollution and control group. The study concluded that exposure to PM≤2.5 causes behavioral changes characteristic of depression and anxiety in adult male rats exposed during the developmental period. |
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Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental studyEXPOSIÇÃO PÓS-NATAL A POLUENTES DO AR (MP≤2,5) COMO FATOR DE RISCO PARA O DESENVOLVIMENTO DE COMPORTAMENTOS DE DEPRESSÃO E ANSIEDADE: UM ESTUDO EXPERIMENTALThe purpose of study was to evaluate the behavioral changes of male and female adult rats exposed to fine and ultrafine particulate matter (PM≤2,5) suspended in air pollution during development. Wistar rats aged 7 days postnatal were exposed to the chamber of an atmospheric particle concentrator. Open field tests and sucrose preference tests were performed to assess the presence of anxiety and depression behaviors. Male rats from the pollution group showed reduced locomotor activity and length of stay in the open field center when compared to the control group males. The sucrose preference test showed statistical significance between the pollution and control groups, and among the males of the pollution and control group. The study concluded that exposure to PM≤2.5 causes behavioral changes characteristic of depression and anxiety in adult male rats exposed during the developmental period.O objetivo do estudo foi avaliar as alterações comportamentais de ratos machos e fêmeas adultos, expostos ao material particulado fino e ultrafino (MP≤2,5) suspenso na poluição do ar, durante o desenvolvimento. Ratos Wistar com idade de 7 dias pós-natal, foram expostos à câmara de um concentrador de partículas atmosféricas. Foram realizados os testes de campo aberto e teste de preferência por sacarose para avaliação da presença de comportamentos de ansiedade e depressão. Ratos machos do grupo poluição apresentaram redução da atividade locomotora e do tempo de permanência no centro do campo aberto quando comparados aos machos do grupo controle. O teste de preferência por sacarose evidenciou significância estatística entre os grupos poluição e controle, e entre os machos do grupo poluição e controle. O estudo concluiu que a exposição ao MP≤2,5 causa alterações comportamentais características de depressão e ansiedade, em ratos machos adultos expostos durante o período de desenvolvimento. Universidade do Oeste Paulista - UNOESTE2020-01-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por paresapplication/pdfhttp://revistas.unoeste.br/index.php/cv/article/view/3266Colloquium Vitae. ISSN: 1984-6436; v. 11 n. 3 (2019): Colloquium Vitae, Vol. 11, n. 3; 20-311984-6436reponame:Colloquium Vitaeinstname:Universidade do Oeste Paulista (UNOESTE)instacron:UNIOESTEporhttp://revistas.unoeste.br/index.php/cv/article/view/3266/2909Copyright (c) 2020 Colloquium Vitae. ISSN: 1984-6436info:eu-repo/semantics/openAccessde Oliveira Carletti, CarlaCorreia Santos, RodrigoFernando Sierra de Araújo, LuisAmérico de Paiva Santos, MuriloMatera Veras, MarianaHelena da Silva , ReginaJose da Silva Fernandes, Maria2020-07-03T17:49:27Zoai:ojs.pkp.sfu.ca:article/3266Revistahttps://revistas.unoeste.br/index.php/cv/indexONGhttp://revistas.unoeste.br/revistas/ojs/index.php/cv/oaijgjunior@unoeste.br||jgjunior@unoeste.br1984-64361984-6436opendoar:2020-07-03T17:49:27Colloquium Vitae - Universidade do Oeste Paulista (UNOESTE)false |
| dc.title.none.fl_str_mv |
Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental study EXPOSIÇÃO PÓS-NATAL A POLUENTES DO AR (MP≤2,5) COMO FATOR DE RISCO PARA O DESENVOLVIMENTO DE COMPORTAMENTOS DE DEPRESSÃO E ANSIEDADE: UM ESTUDO EXPERIMENTAL |
| title |
Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental study |
| spellingShingle |
Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental study de Oliveira Carletti, Carla |
| title_short |
Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental study |
| title_full |
Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental study |
| title_fullStr |
Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental study |
| title_full_unstemmed |
Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental study |
| title_sort |
Postnatal exposure to air pollutants PM≤2,5 as risk factor for the development of depression and anxiety: an experimental study |
| author |
de Oliveira Carletti, Carla |
| author_facet |
de Oliveira Carletti, Carla Correia Santos, Rodrigo Fernando Sierra de Araújo, Luis Américo de Paiva Santos, Murilo Matera Veras, Mariana Helena da Silva , Regina Jose da Silva Fernandes, Maria |
| author_role |
author |
| author2 |
Correia Santos, Rodrigo Fernando Sierra de Araújo, Luis Américo de Paiva Santos, Murilo Matera Veras, Mariana Helena da Silva , Regina Jose da Silva Fernandes, Maria |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
de Oliveira Carletti, Carla Correia Santos, Rodrigo Fernando Sierra de Araújo, Luis Américo de Paiva Santos, Murilo Matera Veras, Mariana Helena da Silva , Regina Jose da Silva Fernandes, Maria |
| description |
The purpose of study was to evaluate the behavioral changes of male and female adult rats exposed to fine and ultrafine particulate matter (PM≤2,5) suspended in air pollution during development. Wistar rats aged 7 days postnatal were exposed to the chamber of an atmospheric particle concentrator. Open field tests and sucrose preference tests were performed to assess the presence of anxiety and depression behaviors. Male rats from the pollution group showed reduced locomotor activity and length of stay in the open field center when compared to the control group males. The sucrose preference test showed statistical significance between the pollution and control groups, and among the males of the pollution and control group. The study concluded that exposure to PM≤2.5 causes behavioral changes characteristic of depression and anxiety in adult male rats exposed during the developmental period. |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2020-01-17 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado por pares |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://revistas.unoeste.br/index.php/cv/article/view/3266 |
| url |
http://revistas.unoeste.br/index.php/cv/article/view/3266 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.none.fl_str_mv |
http://revistas.unoeste.br/index.php/cv/article/view/3266/2909 |
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Copyright (c) 2020 Colloquium Vitae. ISSN: 1984-6436 info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
Copyright (c) 2020 Colloquium Vitae. ISSN: 1984-6436 |
| eu_rights_str_mv |
openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Universidade do Oeste Paulista - UNOESTE |
| publisher.none.fl_str_mv |
Universidade do Oeste Paulista - UNOESTE |
| dc.source.none.fl_str_mv |
Colloquium Vitae. ISSN: 1984-6436; v. 11 n. 3 (2019): Colloquium Vitae, Vol. 11, n. 3; 20-31 1984-6436 reponame:Colloquium Vitae instname:Universidade do Oeste Paulista (UNOESTE) instacron:UNIOESTE |
| instname_str |
Universidade do Oeste Paulista (UNOESTE) |
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UNIOESTE |
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UNIOESTE |
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Colloquium Vitae |
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Colloquium Vitae |
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Colloquium Vitae - Universidade do Oeste Paulista (UNOESTE) |
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jgjunior@unoeste.br||jgjunior@unoeste.br |
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1800218925550534656 |