THERE IS NO CORRELATION BETWEEN STAGES OF NAFLD ASSESSED BY LIVER BIOPSY AND THE DIAGNOSTIC CRITERIA FOR SARCOPENIA IN ACTIVE POPULATIONS: A CROSS-SECTIONAL STUDY
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Arquivos de Ciências da Saúde da UNIPAR (Online) |
Texto Completo: | https://revistas.unipar.br/index.php/saude/article/view/10742 |
Resumo: | Objective: To demonstrate the correlations of the diagnostic criteria for sarcopenia and the levels of Non-alcoholic Fat Liver Disease (NAFLD) assessed by liver biopsy in a physically active population. Methods: Cross-sectional study. Individuals aged >18 years, with NAFLD confirmed by liver biopsy, physically active. Sarcopenia assessment followed EWGSOP2: muscle strength by handgrip, Skeletal Muscle Mass by Bioimpedance, and physical performance by usual gait speed. Statistical Analysis: To test differences between groups in continuous variables, Student's T or Mann-Whitney U Test for independent samples. Pearson and Spearman tests were used for correlations. A 5% significance was considered (p<0.05). Results: 52 patients with NAFLD included, consisting of 35 women and 15 men. There was no difference in age or anthropometric variables. Were found difference statically significant in platelets (higher in women), basal insulin, HOMA-IR and Quick (higher in men). In sarcopenia, the handgrip strength showed difference in favors of men. There was no statistically significant correlation between the sarcopenia and NAFLD levels. Discussion: sarcopenia has been reported as an independent risk factor for NAFLD and its progressions. The physical exercise is one of the most recommended and more effective treatment for both conditions, so is expected that a non-sedentary individual can reduce both indicators. However, there is no consensus about the best method. Also, the both conditions share heterogeneity in diagnosis, prognosis, reason for develop and risk factors across the literature. Conclusion: For populations where most individuals are physically active, it is not possible to find correlation between sarcopenia diagnostic criteria and the stages of NAFLD. |
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Arquivos de Ciências da Saúde da UNIPAR (Online) |
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THERE IS NO CORRELATION BETWEEN STAGES OF NAFLD ASSESSED BY LIVER BIOPSY AND THE DIAGNOSTIC CRITERIA FOR SARCOPENIA IN ACTIVE POPULATIONS: A CROSS-SECTIONAL STUDYNon-Alcoholic Fatty Liver DiseaseSarcopeniaExerciseObjective: To demonstrate the correlations of the diagnostic criteria for sarcopenia and the levels of Non-alcoholic Fat Liver Disease (NAFLD) assessed by liver biopsy in a physically active population. Methods: Cross-sectional study. Individuals aged >18 years, with NAFLD confirmed by liver biopsy, physically active. Sarcopenia assessment followed EWGSOP2: muscle strength by handgrip, Skeletal Muscle Mass by Bioimpedance, and physical performance by usual gait speed. Statistical Analysis: To test differences between groups in continuous variables, Student's T or Mann-Whitney U Test for independent samples. Pearson and Spearman tests were used for correlations. A 5% significance was considered (p<0.05). Results: 52 patients with NAFLD included, consisting of 35 women and 15 men. There was no difference in age or anthropometric variables. Were found difference statically significant in platelets (higher in women), basal insulin, HOMA-IR and Quick (higher in men). In sarcopenia, the handgrip strength showed difference in favors of men. There was no statistically significant correlation between the sarcopenia and NAFLD levels. Discussion: sarcopenia has been reported as an independent risk factor for NAFLD and its progressions. The physical exercise is one of the most recommended and more effective treatment for both conditions, so is expected that a non-sedentary individual can reduce both indicators. However, there is no consensus about the best method. Also, the both conditions share heterogeneity in diagnosis, prognosis, reason for develop and risk factors across the literature. Conclusion: For populations where most individuals are physically active, it is not possible to find correlation between sarcopenia diagnostic criteria and the stages of NAFLD.UNIPAR2023-10-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistas.unipar.br/index.php/saude/article/view/1074210.25110/arqsaude.v27i10.2023-032Arquivos de Ciências da Saúde da UNIPAR; v. 27 n. 10 (2023); 5961-59731982-114Xreponame:Arquivos de Ciências da Saúde da UNIPAR (Online)instname:Universidade Paranaense (UNIPAR)instacron:UNIPARporhttps://revistas.unipar.br/index.php/saude/article/view/10742/5195Copyright (c) 2023 Arquivos de Ciências da Saúde da UNIPARhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFerreira, Luis FernandoBerleze, Kally JanainaD´Ávila, André FerreiraTovo, Cristiane Valleda Rosa, Luis Henrique Telles2023-10-27T15:32:06Zoai:ojs2.revistas.unipar.br:article/10742Revistahttp://revistas.unipar.br/index.php/saudehttp://revistas.unipar.br/saude/oai||cedic@unipar.br|| arqsaude@unipar.br1982-114X1415-076Xopendoar:2023-10-27T15:32:06Arquivos de Ciências da Saúde da UNIPAR (Online) - Universidade Paranaense (UNIPAR)false |
dc.title.none.fl_str_mv |
THERE IS NO CORRELATION BETWEEN STAGES OF NAFLD ASSESSED BY LIVER BIOPSY AND THE DIAGNOSTIC CRITERIA FOR SARCOPENIA IN ACTIVE POPULATIONS: A CROSS-SECTIONAL STUDY |
title |
THERE IS NO CORRELATION BETWEEN STAGES OF NAFLD ASSESSED BY LIVER BIOPSY AND THE DIAGNOSTIC CRITERIA FOR SARCOPENIA IN ACTIVE POPULATIONS: A CROSS-SECTIONAL STUDY |
spellingShingle |
THERE IS NO CORRELATION BETWEEN STAGES OF NAFLD ASSESSED BY LIVER BIOPSY AND THE DIAGNOSTIC CRITERIA FOR SARCOPENIA IN ACTIVE POPULATIONS: A CROSS-SECTIONAL STUDY Ferreira, Luis Fernando Non-Alcoholic Fatty Liver Disease Sarcopenia Exercise |
title_short |
THERE IS NO CORRELATION BETWEEN STAGES OF NAFLD ASSESSED BY LIVER BIOPSY AND THE DIAGNOSTIC CRITERIA FOR SARCOPENIA IN ACTIVE POPULATIONS: A CROSS-SECTIONAL STUDY |
title_full |
THERE IS NO CORRELATION BETWEEN STAGES OF NAFLD ASSESSED BY LIVER BIOPSY AND THE DIAGNOSTIC CRITERIA FOR SARCOPENIA IN ACTIVE POPULATIONS: A CROSS-SECTIONAL STUDY |
title_fullStr |
THERE IS NO CORRELATION BETWEEN STAGES OF NAFLD ASSESSED BY LIVER BIOPSY AND THE DIAGNOSTIC CRITERIA FOR SARCOPENIA IN ACTIVE POPULATIONS: A CROSS-SECTIONAL STUDY |
title_full_unstemmed |
THERE IS NO CORRELATION BETWEEN STAGES OF NAFLD ASSESSED BY LIVER BIOPSY AND THE DIAGNOSTIC CRITERIA FOR SARCOPENIA IN ACTIVE POPULATIONS: A CROSS-SECTIONAL STUDY |
title_sort |
THERE IS NO CORRELATION BETWEEN STAGES OF NAFLD ASSESSED BY LIVER BIOPSY AND THE DIAGNOSTIC CRITERIA FOR SARCOPENIA IN ACTIVE POPULATIONS: A CROSS-SECTIONAL STUDY |
author |
Ferreira, Luis Fernando |
author_facet |
Ferreira, Luis Fernando Berleze, Kally Janaina D´Ávila, André Ferreira Tovo, Cristiane Valle da Rosa, Luis Henrique Telles |
author_role |
author |
author2 |
Berleze, Kally Janaina D´Ávila, André Ferreira Tovo, Cristiane Valle da Rosa, Luis Henrique Telles |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ferreira, Luis Fernando Berleze, Kally Janaina D´Ávila, André Ferreira Tovo, Cristiane Valle da Rosa, Luis Henrique Telles |
dc.subject.por.fl_str_mv |
Non-Alcoholic Fatty Liver Disease Sarcopenia Exercise |
topic |
Non-Alcoholic Fatty Liver Disease Sarcopenia Exercise |
description |
Objective: To demonstrate the correlations of the diagnostic criteria for sarcopenia and the levels of Non-alcoholic Fat Liver Disease (NAFLD) assessed by liver biopsy in a physically active population. Methods: Cross-sectional study. Individuals aged >18 years, with NAFLD confirmed by liver biopsy, physically active. Sarcopenia assessment followed EWGSOP2: muscle strength by handgrip, Skeletal Muscle Mass by Bioimpedance, and physical performance by usual gait speed. Statistical Analysis: To test differences between groups in continuous variables, Student's T or Mann-Whitney U Test for independent samples. Pearson and Spearman tests were used for correlations. A 5% significance was considered (p<0.05). Results: 52 patients with NAFLD included, consisting of 35 women and 15 men. There was no difference in age or anthropometric variables. Were found difference statically significant in platelets (higher in women), basal insulin, HOMA-IR and Quick (higher in men). In sarcopenia, the handgrip strength showed difference in favors of men. There was no statistically significant correlation between the sarcopenia and NAFLD levels. Discussion: sarcopenia has been reported as an independent risk factor for NAFLD and its progressions. The physical exercise is one of the most recommended and more effective treatment for both conditions, so is expected that a non-sedentary individual can reduce both indicators. However, there is no consensus about the best method. Also, the both conditions share heterogeneity in diagnosis, prognosis, reason for develop and risk factors across the literature. Conclusion: For populations where most individuals are physically active, it is not possible to find correlation between sarcopenia diagnostic criteria and the stages of NAFLD. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-10-27 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistas.unipar.br/index.php/saude/article/view/10742 10.25110/arqsaude.v27i10.2023-032 |
url |
https://revistas.unipar.br/index.php/saude/article/view/10742 |
identifier_str_mv |
10.25110/arqsaude.v27i10.2023-032 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revistas.unipar.br/index.php/saude/article/view/10742/5195 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2023 Arquivos de Ciências da Saúde da UNIPAR https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2023 Arquivos de Ciências da Saúde da UNIPAR https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
UNIPAR |
publisher.none.fl_str_mv |
UNIPAR |
dc.source.none.fl_str_mv |
Arquivos de Ciências da Saúde da UNIPAR; v. 27 n. 10 (2023); 5961-5973 1982-114X reponame:Arquivos de Ciências da Saúde da UNIPAR (Online) instname:Universidade Paranaense (UNIPAR) instacron:UNIPAR |
instname_str |
Universidade Paranaense (UNIPAR) |
instacron_str |
UNIPAR |
institution |
UNIPAR |
reponame_str |
Arquivos de Ciências da Saúde da UNIPAR (Online) |
collection |
Arquivos de Ciências da Saúde da UNIPAR (Online) |
repository.name.fl_str_mv |
Arquivos de Ciências da Saúde da UNIPAR (Online) - Universidade Paranaense (UNIPAR) |
repository.mail.fl_str_mv |
||cedic@unipar.br|| arqsaude@unipar.br |
_version_ |
1800218858011754496 |