Chronic hepatitis B and hepatitis D superinfection in patients in the brazilian Western Amazon.
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista de Epidemiologia e Controle de Infecção |
Texto Completo: | https://online.unisc.br/seer/index.php/epidemiologia/article/view/5442 |
Resumo: | Background and Objectives: Once Hepatitis B is a global public health problem, and the disease, when associated with Hepatitis D develops a severe clinical patterns. This study aims to approach this correlation between both hepatitis viruses. In Brazil, HBV and HDV infections have elevated indicators in the western Amazon, where usually is reported clinical severe manifestations of the disease, and also death from fulminant infection. The objective was to compare clinical, biochemical and serological aspects of patients infected by HBV with those patients superinfected by HDV. Method: Descriptive study based on secondary data from medical records of 208 patients. These patients were divided into two (2) groups (HBV and HBV+HDV), followed in Hepatology Clinic from Sanitary Dermatology Hospital in Cruzeiro do Sul city, Acre state, a regional reference healthcenter. Results: 42.8% - of the 208 records analyzed - have presented HBV infection, and 57.2% were diagnosed with coinfection, ie. HBV+HDV, associated hepatitis viruses infection. Both patients group were predominantly male (67.4% = HBV, and 67.2% = HBV+HDV), aged between 12 and 31 years old. Regarding the analysis of clinical, serological, biochemical and hematological, an overview have showed that, the group with associated HBV+HDV infection presented a poorer prognosis compared to the group with HBV monoinfection. Conclusion: It is possible to assert that superinfection by HDV, in the western Brazilian Amazon, is a serious health problem. It is necessary to carry out studies, especially with clinical approach, concerning chronically ill patients. KEYWORDS: hepatitis B. hepatitis D. gastroenterology. |
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Chronic hepatitis B and hepatitis D superinfection in patients in the brazilian Western Amazon.Hepatite B crônica e a superinfecção por vírus D em pacientes na Amazônia Ocidental brasileiraBackground and Objectives: Once Hepatitis B is a global public health problem, and the disease, when associated with Hepatitis D develops a severe clinical patterns. This study aims to approach this correlation between both hepatitis viruses. In Brazil, HBV and HDV infections have elevated indicators in the western Amazon, where usually is reported clinical severe manifestations of the disease, and also death from fulminant infection. The objective was to compare clinical, biochemical and serological aspects of patients infected by HBV with those patients superinfected by HDV. Method: Descriptive study based on secondary data from medical records of 208 patients. These patients were divided into two (2) groups (HBV and HBV+HDV), followed in Hepatology Clinic from Sanitary Dermatology Hospital in Cruzeiro do Sul city, Acre state, a regional reference healthcenter. Results: 42.8% - of the 208 records analyzed - have presented HBV infection, and 57.2% were diagnosed with coinfection, ie. HBV+HDV, associated hepatitis viruses infection. Both patients group were predominantly male (67.4% = HBV, and 67.2% = HBV+HDV), aged between 12 and 31 years old. Regarding the analysis of clinical, serological, biochemical and hematological, an overview have showed that, the group with associated HBV+HDV infection presented a poorer prognosis compared to the group with HBV monoinfection. Conclusion: It is possible to assert that superinfection by HDV, in the western Brazilian Amazon, is a serious health problem. It is necessary to carry out studies, especially with clinical approach, concerning chronically ill patients. KEYWORDS: hepatitis B. hepatitis D. gastroenterology.Justificativa e objetivos: a hepatite B representa um problema de saúde pública de proporção mundial, sendo que a doença, quando associada à infecção por vírus D, desenvolve padrões clínicos severos. No Brasil, as infecções por vírus B (VHB) e D (VHD) apresentam indicadores elevados na região da Amazônia ocidental, onde são comuns os relatos de quadros graves da doença e mortes por hepatite fulminante. Os objetivos do presente estudo foram correlacionar aspectos clínicos, bioquímicos e sorológicos entre pacientes com infecção por VHB e aqueles superinfectados por VHD. Método: estudo descritivo com informações provenientes de fonte de dados secundários registrados em 208 prontuários de pacientes, divididos em grupos (VHB e VHB+VHD), acompanhados no ambulatório de hepatologia do Hospital de Dermatologia Sanitária na cidade de Cruzeiro do Sul, Acre, centro de referência da regional. Resultados: dos 208 prontuários analisados, 42,8% apresentaram infecção por VHB e 57,2% apresentaram diagnóstico de VHB associada ao VHD. Para ambos os grupos houve predominância do sexo masculino (VHB = 67,4% e VHB+VHD = 67,2%), com faixa etária entre 12 e 31 anos. Quanto à análise dos aspectos clínicos, sorológicos, bioquímicos e hematológicos, de modo geral, o grupo com infecção associada ao vírus D apresentou pior prognóstico frente ao grupo com monoinfecção por vírus B. Conclusão: a superinfecção por vírus D na Amazônia ocidental brasileira representa um grave problema de saúde, sendo necessários novos estudos, principalmente com abordagem clínica, com relação aos pacientes cronicamente afetados pela doença. DESCRITORES: Hepatite B. Hepatite D. Gastroenterologia.Unisc2015-04-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://online.unisc.br/seer/index.php/epidemiologia/article/view/544210.17058/reci.v5i2.5442Revista de Epidemiologia e Controle de Infecção; Vol. 5 No. 2 (2015); 72-78Revista de Epidemiologia e Controle de Infecção; v. 5 n. 2 (2015); 72-782238-3360reponame:Revista de Epidemiologia e Controle de Infecçãoinstname:Universidade de Santa Cruz do Sul (UNISC)instacron:UNISCporhttps://online.unisc.br/seer/index.php/epidemiologia/article/view/5442/4293Oliveira, Marcelo Siqueira deValle, Suiane da Costa Negreiros doSilva, Romeu Paulo MartinsFigueiredo, Elisabeth Níglio deinfo:eu-repo/semantics/openAccess2019-01-21T12:55:14Zoai:ojs.online.unisc.br:article/5442Revistahttps://online.unisc.br/seer/index.php/epidemiologia/indexONGhttp://online.unisc.br/seer/index.php/epidemiologia/oai||liapossuelo@unisc.br|| julia.kern@hotmail.com||reci.unisc@gmail.com2238-33602238-3360opendoar:2019-01-21T12:55:14Revista de Epidemiologia e Controle de Infecção - Universidade de Santa Cruz do Sul (UNISC)false |
dc.title.none.fl_str_mv |
Chronic hepatitis B and hepatitis D superinfection in patients in the brazilian Western Amazon. Hepatite B crônica e a superinfecção por vírus D em pacientes na Amazônia Ocidental brasileira |
title |
Chronic hepatitis B and hepatitis D superinfection in patients in the brazilian Western Amazon. |
spellingShingle |
Chronic hepatitis B and hepatitis D superinfection in patients in the brazilian Western Amazon. Oliveira, Marcelo Siqueira de |
title_short |
Chronic hepatitis B and hepatitis D superinfection in patients in the brazilian Western Amazon. |
title_full |
Chronic hepatitis B and hepatitis D superinfection in patients in the brazilian Western Amazon. |
title_fullStr |
Chronic hepatitis B and hepatitis D superinfection in patients in the brazilian Western Amazon. |
title_full_unstemmed |
Chronic hepatitis B and hepatitis D superinfection in patients in the brazilian Western Amazon. |
title_sort |
Chronic hepatitis B and hepatitis D superinfection in patients in the brazilian Western Amazon. |
author |
Oliveira, Marcelo Siqueira de |
author_facet |
Oliveira, Marcelo Siqueira de Valle, Suiane da Costa Negreiros do Silva, Romeu Paulo Martins Figueiredo, Elisabeth Níglio de |
author_role |
author |
author2 |
Valle, Suiane da Costa Negreiros do Silva, Romeu Paulo Martins Figueiredo, Elisabeth Níglio de |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Marcelo Siqueira de Valle, Suiane da Costa Negreiros do Silva, Romeu Paulo Martins Figueiredo, Elisabeth Níglio de |
description |
Background and Objectives: Once Hepatitis B is a global public health problem, and the disease, when associated with Hepatitis D develops a severe clinical patterns. This study aims to approach this correlation between both hepatitis viruses. In Brazil, HBV and HDV infections have elevated indicators in the western Amazon, where usually is reported clinical severe manifestations of the disease, and also death from fulminant infection. The objective was to compare clinical, biochemical and serological aspects of patients infected by HBV with those patients superinfected by HDV. Method: Descriptive study based on secondary data from medical records of 208 patients. These patients were divided into two (2) groups (HBV and HBV+HDV), followed in Hepatology Clinic from Sanitary Dermatology Hospital in Cruzeiro do Sul city, Acre state, a regional reference healthcenter. Results: 42.8% - of the 208 records analyzed - have presented HBV infection, and 57.2% were diagnosed with coinfection, ie. HBV+HDV, associated hepatitis viruses infection. Both patients group were predominantly male (67.4% = HBV, and 67.2% = HBV+HDV), aged between 12 and 31 years old. Regarding the analysis of clinical, serological, biochemical and hematological, an overview have showed that, the group with associated HBV+HDV infection presented a poorer prognosis compared to the group with HBV monoinfection. Conclusion: It is possible to assert that superinfection by HDV, in the western Brazilian Amazon, is a serious health problem. It is necessary to carry out studies, especially with clinical approach, concerning chronically ill patients. KEYWORDS: hepatitis B. hepatitis D. gastroenterology. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-04-04 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://online.unisc.br/seer/index.php/epidemiologia/article/view/5442 10.17058/reci.v5i2.5442 |
url |
https://online.unisc.br/seer/index.php/epidemiologia/article/view/5442 |
identifier_str_mv |
10.17058/reci.v5i2.5442 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://online.unisc.br/seer/index.php/epidemiologia/article/view/5442/4293 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Unisc |
publisher.none.fl_str_mv |
Unisc |
dc.source.none.fl_str_mv |
Revista de Epidemiologia e Controle de Infecção; Vol. 5 No. 2 (2015); 72-78 Revista de Epidemiologia e Controle de Infecção; v. 5 n. 2 (2015); 72-78 2238-3360 reponame:Revista de Epidemiologia e Controle de Infecção instname:Universidade de Santa Cruz do Sul (UNISC) instacron:UNISC |
instname_str |
Universidade de Santa Cruz do Sul (UNISC) |
instacron_str |
UNISC |
institution |
UNISC |
reponame_str |
Revista de Epidemiologia e Controle de Infecção |
collection |
Revista de Epidemiologia e Controle de Infecção |
repository.name.fl_str_mv |
Revista de Epidemiologia e Controle de Infecção - Universidade de Santa Cruz do Sul (UNISC) |
repository.mail.fl_str_mv |
||liapossuelo@unisc.br|| julia.kern@hotmail.com||reci.unisc@gmail.com |
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