Analysis of of medication and potential interactions in prescriptions containing antimicrobials distributed in a community pharmacy in the city of Ijuí /RS
Autor(a) principal: | |
---|---|
Data de Publicação: | 2012 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista de Epidemiologia e Controle de Infecção |
Texto Completo: | https://online.unisc.br/seer/index.php/epidemiologia/article/view/2753 |
Resumo: | Rationale and Objectives: Bacterial resistance is a worldwide concern and the inappropriate prescription of antimicrobials is one of the factors that can infl uence its rates. The objective was to evaluate the prescriptions containing antimicrobials distributed in a community pharmacy in the municipality of Ijuí / RS, to identify the antimicrobials and the drugs prescribed in combination, as well as potential drug interactions. Methods: The sample consisted of prescriptions retained at the study site from November 28 2010 to March 31 2011, which contained at least one antimicrobial listed in Appendix I of RDC 44/2010. Results: A total of 268 prescriptions were analyzed, containing 283 antimicrobials; 15 prescriptions had two drugs. The class of penicillins, found in 30.04% of prescriptions, and quinolones (23.67%) were the most commonly prescribed drugs. In 45.9% of prescriptions, at least one drug was associated with an antimicrobial agent, totaling 167 medications, primarily the class of analgesics and antipyretics (43.11%) and non-steroidal anti-infl ammatory and anti-rheumatic drugs (29.94 %). The non-steroidal anti-infl ammatory and anti-rheumatic drugs were present in 39% of 82.05% potential drug interactions found, with penicillin being the main class of antimicrobials involved in the interaction (64.1%). Conclusion: Professionals responsible for prescribing and dispensing drugs should be able to identify and prevent drug interactions, providing more safety for the user and treatment effectiveness. It is understood that it is necessary to review and standardize the criteria for drug prescription, distribution and administration in order to rationalize the use of antimicrobials. KEYWORDS: Drug prescriptions. Drug interactions. Antimicrobials |
id |
UNISC-4_b9e4c8f64f0d67e9d7ae09f057e472f1 |
---|---|
oai_identifier_str |
oai:ojs.online.unisc.br:article/2753 |
network_acronym_str |
UNISC-4 |
network_name_str |
Revista de Epidemiologia e Controle de Infecção |
repository_id_str |
|
spelling |
Analysis of of medication and potential interactions in prescriptions containing antimicrobials distributed in a community pharmacy in the city of Ijuí /RSAnálise de dos medicamentos e interações petenciais em prescrições contendo antimicrobianos dispensados em uma farmácia comunitária de Ijuí/RSRationale and Objectives: Bacterial resistance is a worldwide concern and the inappropriate prescription of antimicrobials is one of the factors that can infl uence its rates. The objective was to evaluate the prescriptions containing antimicrobials distributed in a community pharmacy in the municipality of Ijuí / RS, to identify the antimicrobials and the drugs prescribed in combination, as well as potential drug interactions. Methods: The sample consisted of prescriptions retained at the study site from November 28 2010 to March 31 2011, which contained at least one antimicrobial listed in Appendix I of RDC 44/2010. Results: A total of 268 prescriptions were analyzed, containing 283 antimicrobials; 15 prescriptions had two drugs. The class of penicillins, found in 30.04% of prescriptions, and quinolones (23.67%) were the most commonly prescribed drugs. In 45.9% of prescriptions, at least one drug was associated with an antimicrobial agent, totaling 167 medications, primarily the class of analgesics and antipyretics (43.11%) and non-steroidal anti-infl ammatory and anti-rheumatic drugs (29.94 %). The non-steroidal anti-infl ammatory and anti-rheumatic drugs were present in 39% of 82.05% potential drug interactions found, with penicillin being the main class of antimicrobials involved in the interaction (64.1%). Conclusion: Professionals responsible for prescribing and dispensing drugs should be able to identify and prevent drug interactions, providing more safety for the user and treatment effectiveness. It is understood that it is necessary to review and standardize the criteria for drug prescription, distribution and administration in order to rationalize the use of antimicrobials. KEYWORDS: Drug prescriptions. Drug interactions. AntimicrobialsJustifi cativa e Objetivos: A resistência bacteriana se constitui em preocupação mundial e a prescrição inadequada de antimicrobianos é um dos fatores que pode infl uenciar nas suas taxas. O objetivo foi avaliar as prescrições contendo antimicrobianos dispensados em uma farmácia comunitária do município de Ijuí/RS, para identifi car os antimicrobianos e os fármacos prescritos em associação, bem como interações medicamentosas potenciais. Métodos: A amostra foi constituída por prescrições retidas no local do estudo, de 28 de novembro de 2010 a 31 de março de 2011, que continham ao menos um antimicrobiano listado no Anexo I da RDC 44/2010. Resultados: Foram analisadas 268 prescrições, contendo 283 antimicrobianos, em 15 prescrições foram prescritos dois produtos. A classe das penicilinas, presente em 30,04% das prescrições, e as quinolonas (23,67%) foram os mais prescritos. Em 45,9% das prescrições, pelo menos mais um medicamento foi associado ao antimicrobiano, totalizando 167 medicamentos, sendo principalmente a classe dos analgésicos e antipiréticos (43,11%) e dos antiinfl amatórios e antirreumáticos não-esteróides (29,94%). Os antiinfl amatórios e antirreumáticos não-esteróides estavam presentes em 82,05% das 39 interações medicamentosas potenciais encontradas, sendo que a principal classe de antimicrobianos envolvida foi a das penicilinas (64,1%). Conclusão: é necessário que os profi ssionais responsáveis pela prescrição e pela dispensação estejam capacitados para identifi car e evitar a presença de interações medicamentosas, proporcionando mais segurança para o usuário e efetividade no tratamento. Entende-se que seja necessário rever e padronizar os critérios de prescrição, dispensação e administração, a fi m de racionalizar o uso dos antimicrobianos.Unisc2012-10-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://online.unisc.br/seer/index.php/epidemiologia/article/view/275310.17058/reci.v2i4.2753Revista de Epidemiologia e Controle de Infecção; Vol. 2 No. 4 (2012); 122-127Revista de Epidemiologia e Controle de Infecção; v. 2 n. 4 (2012); 122-1272238-3360reponame:Revista de Epidemiologia e Controle de Infecçãoinstname:Universidade de Santa Cruz do Sul (UNISC)instacron:UNISCporhttps://online.unisc.br/seer/index.php/epidemiologia/article/view/2753/2368Weber, Bruna RodriguesScherer, Vanessa CristinaOliveira, Karla RenataColet, Christiane Fátimainfo:eu-repo/semantics/openAccess2019-01-21T12:59:24Zoai:ojs.online.unisc.br:article/2753Revistahttps://online.unisc.br/seer/index.php/epidemiologia/indexONGhttp://online.unisc.br/seer/index.php/epidemiologia/oai||liapossuelo@unisc.br|| julia.kern@hotmail.com||reci.unisc@gmail.com2238-33602238-3360opendoar:2019-01-21T12:59:24Revista de Epidemiologia e Controle de Infecção - Universidade de Santa Cruz do Sul (UNISC)false |
dc.title.none.fl_str_mv |
Analysis of of medication and potential interactions in prescriptions containing antimicrobials distributed in a community pharmacy in the city of Ijuí /RS Análise de dos medicamentos e interações petenciais em prescrições contendo antimicrobianos dispensados em uma farmácia comunitária de Ijuí/RS |
title |
Analysis of of medication and potential interactions in prescriptions containing antimicrobials distributed in a community pharmacy in the city of Ijuí /RS |
spellingShingle |
Analysis of of medication and potential interactions in prescriptions containing antimicrobials distributed in a community pharmacy in the city of Ijuí /RS Weber, Bruna Rodrigues |
title_short |
Analysis of of medication and potential interactions in prescriptions containing antimicrobials distributed in a community pharmacy in the city of Ijuí /RS |
title_full |
Analysis of of medication and potential interactions in prescriptions containing antimicrobials distributed in a community pharmacy in the city of Ijuí /RS |
title_fullStr |
Analysis of of medication and potential interactions in prescriptions containing antimicrobials distributed in a community pharmacy in the city of Ijuí /RS |
title_full_unstemmed |
Analysis of of medication and potential interactions in prescriptions containing antimicrobials distributed in a community pharmacy in the city of Ijuí /RS |
title_sort |
Analysis of of medication and potential interactions in prescriptions containing antimicrobials distributed in a community pharmacy in the city of Ijuí /RS |
author |
Weber, Bruna Rodrigues |
author_facet |
Weber, Bruna Rodrigues Scherer, Vanessa Cristina Oliveira, Karla Renata Colet, Christiane Fátima |
author_role |
author |
author2 |
Scherer, Vanessa Cristina Oliveira, Karla Renata Colet, Christiane Fátima |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Weber, Bruna Rodrigues Scherer, Vanessa Cristina Oliveira, Karla Renata Colet, Christiane Fátima |
description |
Rationale and Objectives: Bacterial resistance is a worldwide concern and the inappropriate prescription of antimicrobials is one of the factors that can infl uence its rates. The objective was to evaluate the prescriptions containing antimicrobials distributed in a community pharmacy in the municipality of Ijuí / RS, to identify the antimicrobials and the drugs prescribed in combination, as well as potential drug interactions. Methods: The sample consisted of prescriptions retained at the study site from November 28 2010 to March 31 2011, which contained at least one antimicrobial listed in Appendix I of RDC 44/2010. Results: A total of 268 prescriptions were analyzed, containing 283 antimicrobials; 15 prescriptions had two drugs. The class of penicillins, found in 30.04% of prescriptions, and quinolones (23.67%) were the most commonly prescribed drugs. In 45.9% of prescriptions, at least one drug was associated with an antimicrobial agent, totaling 167 medications, primarily the class of analgesics and antipyretics (43.11%) and non-steroidal anti-infl ammatory and anti-rheumatic drugs (29.94 %). The non-steroidal anti-infl ammatory and anti-rheumatic drugs were present in 39% of 82.05% potential drug interactions found, with penicillin being the main class of antimicrobials involved in the interaction (64.1%). Conclusion: Professionals responsible for prescribing and dispensing drugs should be able to identify and prevent drug interactions, providing more safety for the user and treatment effectiveness. It is understood that it is necessary to review and standardize the criteria for drug prescription, distribution and administration in order to rationalize the use of antimicrobials. KEYWORDS: Drug prescriptions. Drug interactions. Antimicrobials |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-10-04 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://online.unisc.br/seer/index.php/epidemiologia/article/view/2753 10.17058/reci.v2i4.2753 |
url |
https://online.unisc.br/seer/index.php/epidemiologia/article/view/2753 |
identifier_str_mv |
10.17058/reci.v2i4.2753 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://online.unisc.br/seer/index.php/epidemiologia/article/view/2753/2368 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Unisc |
publisher.none.fl_str_mv |
Unisc |
dc.source.none.fl_str_mv |
Revista de Epidemiologia e Controle de Infecção; Vol. 2 No. 4 (2012); 122-127 Revista de Epidemiologia e Controle de Infecção; v. 2 n. 4 (2012); 122-127 2238-3360 reponame:Revista de Epidemiologia e Controle de Infecção instname:Universidade de Santa Cruz do Sul (UNISC) instacron:UNISC |
instname_str |
Universidade de Santa Cruz do Sul (UNISC) |
instacron_str |
UNISC |
institution |
UNISC |
reponame_str |
Revista de Epidemiologia e Controle de Infecção |
collection |
Revista de Epidemiologia e Controle de Infecção |
repository.name.fl_str_mv |
Revista de Epidemiologia e Controle de Infecção - Universidade de Santa Cruz do Sul (UNISC) |
repository.mail.fl_str_mv |
||liapossuelo@unisc.br|| julia.kern@hotmail.com||reci.unisc@gmail.com |
_version_ |
1800218809322176512 |