Endometrial evaluation in menopausal women after six months of isoflavones [Avaliação do endométrio em menopausadas após uso de isoflavonas]
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Data de Publicação: | 2006 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNITAU |
Texto Completo: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33846848090&doi=10.1590%2fS0104-42302006000600022&partnerID=40&md5=ae2f61b152e64f2886a5f04073429ad2 http://repositorio.unitau.br/jspui/handle/20.500.11874/1680 |
Resumo: | OBJETIVE. To evaluate the endometrium of menopausal women before and after six months use of total isoflavone. METHODS. A non-controlled clinical, type "before and after" trial was carried out with 32 post-menopause women, between 40 and 60 years of age. They received 80mg/day of total isoflavones obtained from Trifolium pratense (Climadilâ) during six months. They were evaluated at the beginning and end of treatment by transvaginal pelvic ecography, hysteroscopy and endometrial biopsy. DATA ANALYSIS. Data collected were registered by means of the Epi info, version 6.04b software, data analysis was made using the SAS version 8.2 statistics program, considering a significance level (a) of 0.05 and a 0.80 power (1-β). In order to study the average variation of endometrial thickness and variation of the hysteroscopic and hystologic findings the t Student test for paired data was used. RESULTS. Among the 32 participant women, six presented vaginal bleeding and three presented endometrial alteration when compared to the initial exams. Two of the women developed endometrial cell proliferation and one of them endometrial hiperplasia. There were no significant alterations in relation to endometrial thickness. CONCLUSION. In this study, three women who used isoflavones during the six month period presented endometrial activity. |
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Wolff L.P.G.Martins, Marcos RobertoBedone A.J.Monteiro I.M.U.1584120820014424545400660227047267014486512019-09-12T16:25:46Z2019-09-12T16:25:46Z200652641942310.1590/S0104-423020060006000221044230https://www.scopus.com/inward/record.uri?eid=2-s2.0-33846848090&doi=10.1590%2fS0104-42302006000600022&partnerID=40&md5=ae2f61b152e64f2886a5f04073429ad2http://repositorio.unitau.br/jspui/handle/20.500.11874/16802-s2.0-33846848090OBJETIVE. To evaluate the endometrium of menopausal women before and after six months use of total isoflavone. METHODS. A non-controlled clinical, type "before and after" trial was carried out with 32 post-menopause women, between 40 and 60 years of age. They received 80mg/day of total isoflavones obtained from Trifolium pratense (Climadilâ) during six months. They were evaluated at the beginning and end of treatment by transvaginal pelvic ecography, hysteroscopy and endometrial biopsy. DATA ANALYSIS. Data collected were registered by means of the Epi info, version 6.04b software, data analysis was made using the SAS version 8.2 statistics program, considering a significance level (a) of 0.05 and a 0.80 power (1-β). In order to study the average variation of endometrial thickness and variation of the hysteroscopic and hystologic findings the t Student test for paired data was used. RESULTS. Among the 32 participant women, six presented vaginal bleeding and three presented endometrial alteration when compared to the initial exams. Two of the women developed endometrial cell proliferation and one of them endometrial hiperplasia. There were no significant alterations in relation to endometrial thickness. CONCLUSION. In this study, three women who used isoflavones during the six month period presented endometrial activity.Made available in DSpace on 2019-09-12T16:25:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2006Wolff, L.P.G., Universidade Estadual de Campinas, Universidade de Taubaté, SP, BrazilMartins, M.R., Universidade Estadual de Campinas, Universidade de Taubaté, SP, BrazilBedone, A.J., Universidade Estadual de Campinas, Universidade de Taubaté, SP, BrazilMonteiro, I.M.U., Universidade Estadual de Campinas, Universidade de Taubaté, SP, Brazil, R. Timburi,532. Cond., Alphaville Campinas - SP, BrazilRevista da Associacao Medica Brasileirahttps://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessScopusreponame:Repositório Institucional da UNITAUinstname:Universidade de Taubaté (UNITAU)instacron:UNITAUEndometriumHysteroscopyIsoflavonesMenopauseisoflavone derivativeadultarticlebiopsydrug effectendometriumendometrium hyperplasiafemalehot flushhumanhyperplasiahysteroscopymenopausemiddle agedpathologyprospective studytimeuterus bleedinguterus diseaseAdultBiopsyEndometrial HyperplasiaEndometriumFemaleHot FlashesHumansHyperplasiaHysteroscopyIsoflavonesMenopauseMiddle AgedProspective StudiesTime FactorsUterine DiseasesUterine HemorrhageEndometrial evaluation in menopausal women after six months of isoflavones [Avaliação do endométrio em menopausadas após uso de isoflavonas]info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleporORIGINAL2-s2.0-33846848090.pdf2-s2.0-33846848090.pdfapplication/pdf92532http://repositorio.unitau.br:8080/jspui/bitstream/20.500.11874/1680/1/2-s2.0-33846848090.pdf5f4c1550740812e3a1db7bf43f2bec2bMD5120.500.11874/16802020-09-17 21:38:15.547oai:repositorio.unitau.br:20.500.11874/1680Repositório InstitucionalPUBhttp://repositorio.unitau.br/oai/requestopendoar:2020-09-18T00:38:15Repositório Institucional da UNITAU - Universidade de Taubaté (UNITAU)false |
dc.title.en.fl_str_mv |
Endometrial evaluation in menopausal women after six months of isoflavones [Avaliação do endométrio em menopausadas após uso de isoflavonas] |
title |
Endometrial evaluation in menopausal women after six months of isoflavones [Avaliação do endométrio em menopausadas após uso de isoflavonas] |
spellingShingle |
Endometrial evaluation in menopausal women after six months of isoflavones [Avaliação do endométrio em menopausadas após uso de isoflavonas] Wolff L.P.G. Endometrium Hysteroscopy Isoflavones Menopause isoflavone derivative adult article biopsy drug effect endometrium endometrium hyperplasia female hot flush human hyperplasia hysteroscopy menopause middle aged pathology prospective study time uterus bleeding uterus disease Adult Biopsy Endometrial Hyperplasia Endometrium Female Hot Flashes Humans Hyperplasia Hysteroscopy Isoflavones Menopause Middle Aged Prospective Studies Time Factors Uterine Diseases Uterine Hemorrhage |
title_short |
Endometrial evaluation in menopausal women after six months of isoflavones [Avaliação do endométrio em menopausadas após uso de isoflavonas] |
title_full |
Endometrial evaluation in menopausal women after six months of isoflavones [Avaliação do endométrio em menopausadas após uso de isoflavonas] |
title_fullStr |
Endometrial evaluation in menopausal women after six months of isoflavones [Avaliação do endométrio em menopausadas após uso de isoflavonas] |
title_full_unstemmed |
Endometrial evaluation in menopausal women after six months of isoflavones [Avaliação do endométrio em menopausadas após uso de isoflavonas] |
title_sort |
Endometrial evaluation in menopausal women after six months of isoflavones [Avaliação do endométrio em menopausadas após uso de isoflavonas] |
author |
Wolff L.P.G. |
author_facet |
Wolff L.P.G. Martins, Marcos Roberto Bedone A.J. Monteiro I.M.U. |
author_role |
author |
author2 |
Martins, Marcos Roberto Bedone A.J. Monteiro I.M.U. |
author2_role |
author author author |
dc.contributor.scopus.pt_BR.fl_str_mv |
15841208200 14424545400 6602270472 6701448651 |
dc.contributor.author.fl_str_mv |
Wolff L.P.G. Martins, Marcos Roberto Bedone A.J. Monteiro I.M.U. |
dc.subject.other.en.fl_str_mv |
Endometrium Hysteroscopy Isoflavones Menopause isoflavone derivative adult article biopsy drug effect endometrium endometrium hyperplasia female hot flush human hyperplasia hysteroscopy menopause middle aged pathology prospective study time uterus bleeding uterus disease Adult Biopsy Endometrial Hyperplasia Endometrium Female Hot Flashes Humans Hyperplasia Hysteroscopy Isoflavones Menopause Middle Aged Prospective Studies Time Factors Uterine Diseases Uterine Hemorrhage |
topic |
Endometrium Hysteroscopy Isoflavones Menopause isoflavone derivative adult article biopsy drug effect endometrium endometrium hyperplasia female hot flush human hyperplasia hysteroscopy menopause middle aged pathology prospective study time uterus bleeding uterus disease Adult Biopsy Endometrial Hyperplasia Endometrium Female Hot Flashes Humans Hyperplasia Hysteroscopy Isoflavones Menopause Middle Aged Prospective Studies Time Factors Uterine Diseases Uterine Hemorrhage |
description |
OBJETIVE. To evaluate the endometrium of menopausal women before and after six months use of total isoflavone. METHODS. A non-controlled clinical, type "before and after" trial was carried out with 32 post-menopause women, between 40 and 60 years of age. They received 80mg/day of total isoflavones obtained from Trifolium pratense (Climadilâ) during six months. They were evaluated at the beginning and end of treatment by transvaginal pelvic ecography, hysteroscopy and endometrial biopsy. DATA ANALYSIS. Data collected were registered by means of the Epi info, version 6.04b software, data analysis was made using the SAS version 8.2 statistics program, considering a significance level (a) of 0.05 and a 0.80 power (1-β). In order to study the average variation of endometrial thickness and variation of the hysteroscopic and hystologic findings the t Student test for paired data was used. RESULTS. Among the 32 participant women, six presented vaginal bleeding and three presented endometrial alteration when compared to the initial exams. Two of the women developed endometrial cell proliferation and one of them endometrial hiperplasia. There were no significant alterations in relation to endometrial thickness. CONCLUSION. In this study, three women who used isoflavones during the six month period presented endometrial activity. |
publishDate |
2006 |
dc.date.issued.fl_str_mv |
2006 |
dc.date.accessioned.fl_str_mv |
2019-09-12T16:25:46Z |
dc.date.available.fl_str_mv |
2019-09-12T16:25:46Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-33846848090&doi=10.1590%2fS0104-42302006000600022&partnerID=40&md5=ae2f61b152e64f2886a5f04073429ad2 http://repositorio.unitau.br/jspui/handle/20.500.11874/1680 |
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Revista da Associacao Medica Brasileira |
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