Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis

Detalhes bibliográficos
Autor(a) principal: Sabes, A. F. [UNESP]
Data de Publicação: 2017
Outros Autores: Girardi, A. M. [UNESP], Filho, D.Zangirolami [UNESP], Bueno, G. M. [UNESP], Oliveira, J. A. [UNESP], Marques, L. C. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/1678-4162-9218
http://hdl.handle.net/11449/169910
Resumo: This study aimed to investigate the changes in the acid-base balance of sheep with experimentally induced acute ruminal lactic acidosis (ARA). Ten ewes orally received 15 grams of sucrose per kilogram of body mass. Arterial blood samples for blood gas analysis were obtained at the following intervals: before the induction of ARA (control), and 2, 4, 6, 8, 10, 12, 16, 20, 24, 28, 32, 36, 48, 72, 96, 120 and 144 hours after sucrose administration. Urine samples for pH measurement were obtained at the following times: -15 days, -7 days, and immediately before sucrose administration, then at 24, 48, 72, 96, 120 and 144 hours. Thereafter, both blood and urine samples were obtained on the 2nd, 3rd, and 4th following weeks. From 4 hours after the induction, elevation of the pH, bicarbonate and base excess on the arterial blood was observed. After 12 hours, the animals showed a decrease of these parameters, as well as urine acidification, which are symptomatic of metabolic acidosis. Within 28 hours, all parameters were normalized except the base excess, which only returned to normal after 72 hours. Despite the occurrence of acidemia, there was no need for medication and no animals died.
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spelling Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosisBlood gas analysisMetabolic acidosisSanta inêsThis study aimed to investigate the changes in the acid-base balance of sheep with experimentally induced acute ruminal lactic acidosis (ARA). Ten ewes orally received 15 grams of sucrose per kilogram of body mass. Arterial blood samples for blood gas analysis were obtained at the following intervals: before the induction of ARA (control), and 2, 4, 6, 8, 10, 12, 16, 20, 24, 28, 32, 36, 48, 72, 96, 120 and 144 hours after sucrose administration. Urine samples for pH measurement were obtained at the following times: -15 days, -7 days, and immediately before sucrose administration, then at 24, 48, 72, 96, 120 and 144 hours. Thereafter, both blood and urine samples were obtained on the 2nd, 3rd, and 4th following weeks. From 4 hours after the induction, elevation of the pH, bicarbonate and base excess on the arterial blood was observed. After 12 hours, the animals showed a decrease of these parameters, as well as urine acidification, which are symptomatic of metabolic acidosis. Within 28 hours, all parameters were normalized except the base excess, which only returned to normal after 72 hours. Despite the occurrence of acidemia, there was no need for medication and no animals died.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Faculdade de Ciências Agrárias e Veterinárias (FCAV) Universidade Estadual Paulista 'Júlio de Mesquita Filho' (UNESP)Faculdade de Ciências Agrárias e Veterinárias (FCAV) Universidade Estadual Paulista 'Júlio de Mesquita Filho' (UNESP)Universidade Estadual Paulista (Unesp)Sabes, A. F. [UNESP]Girardi, A. M. [UNESP]Filho, D.Zangirolami [UNESP]Bueno, G. M. [UNESP]Oliveira, J. A. [UNESP]Marques, L. C. [UNESP]2018-12-11T16:48:09Z2018-12-11T16:48:09Z2017-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article637-643application/pdfhttp://dx.doi.org/10.1590/1678-4162-9218Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, v. 69, n. 3, p. 637-643, 2017.1678-41620102-0935http://hdl.handle.net/11449/16991010.1590/1678-4162-9218S0102-093520170003006372-s2.0-85022204684S0102-09352017000300637.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArquivo Brasileiro de Medicina Veterinaria e Zootecnia0,248info:eu-repo/semantics/openAccess2024-01-21T06:21:20Zoai:repositorio.unesp.br:11449/169910Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:35:02.076102Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis
title Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis
spellingShingle Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis
Sabes, A. F. [UNESP]
Blood gas analysis
Metabolic acidosis
Santa inês
title_short Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis
title_full Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis
title_fullStr Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis
title_full_unstemmed Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis
title_sort Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis
author Sabes, A. F. [UNESP]
author_facet Sabes, A. F. [UNESP]
Girardi, A. M. [UNESP]
Filho, D.Zangirolami [UNESP]
Bueno, G. M. [UNESP]
Oliveira, J. A. [UNESP]
Marques, L. C. [UNESP]
author_role author
author2 Girardi, A. M. [UNESP]
Filho, D.Zangirolami [UNESP]
Bueno, G. M. [UNESP]
Oliveira, J. A. [UNESP]
Marques, L. C. [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Sabes, A. F. [UNESP]
Girardi, A. M. [UNESP]
Filho, D.Zangirolami [UNESP]
Bueno, G. M. [UNESP]
Oliveira, J. A. [UNESP]
Marques, L. C. [UNESP]
dc.subject.por.fl_str_mv Blood gas analysis
Metabolic acidosis
Santa inês
topic Blood gas analysis
Metabolic acidosis
Santa inês
description This study aimed to investigate the changes in the acid-base balance of sheep with experimentally induced acute ruminal lactic acidosis (ARA). Ten ewes orally received 15 grams of sucrose per kilogram of body mass. Arterial blood samples for blood gas analysis were obtained at the following intervals: before the induction of ARA (control), and 2, 4, 6, 8, 10, 12, 16, 20, 24, 28, 32, 36, 48, 72, 96, 120 and 144 hours after sucrose administration. Urine samples for pH measurement were obtained at the following times: -15 days, -7 days, and immediately before sucrose administration, then at 24, 48, 72, 96, 120 and 144 hours. Thereafter, both blood and urine samples were obtained on the 2nd, 3rd, and 4th following weeks. From 4 hours after the induction, elevation of the pH, bicarbonate and base excess on the arterial blood was observed. After 12 hours, the animals showed a decrease of these parameters, as well as urine acidification, which are symptomatic of metabolic acidosis. Within 28 hours, all parameters were normalized except the base excess, which only returned to normal after 72 hours. Despite the occurrence of acidemia, there was no need for medication and no animals died.
publishDate 2017
dc.date.none.fl_str_mv 2017-06-01
2018-12-11T16:48:09Z
2018-12-11T16:48:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/1678-4162-9218
Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, v. 69, n. 3, p. 637-643, 2017.
1678-4162
0102-0935
http://hdl.handle.net/11449/169910
10.1590/1678-4162-9218
S0102-09352017000300637
2-s2.0-85022204684
S0102-09352017000300637.pdf
url http://dx.doi.org/10.1590/1678-4162-9218
http://hdl.handle.net/11449/169910
identifier_str_mv Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, v. 69, n. 3, p. 637-643, 2017.
1678-4162
0102-0935
10.1590/1678-4162-9218
S0102-09352017000300637
2-s2.0-85022204684
S0102-09352017000300637.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinaria e Zootecnia
0,248
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 637-643
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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