Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys

Detalhes bibliográficos
Autor(a) principal: Oliveira, Maria Gláucia Carlos de
Data de Publicação: 2021
Outros Autores: Paula, Valéria Veras de, Mouta, Andressa Nunes, Lima, Isabelle de Oliveira, Macêdo, Luã Barbalho de, Nunes, Talyta Lins, Trindade, Pedro Henrique Esteves [UNESP], Luna, Stelio Pacca Loureiro [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3389/fvets.2021.671330
http://hdl.handle.net/11449/229059
Resumo: This study aimed to validate a scale for assessing acute pain in donkeys. Forty-four adult donkeys underwent castration after sedation with intravenous (IV) xylazine, induction with guaifenesin and thiopental IV, local anesthetic block, and maintenance with isoflurane. The scale was constructed from a pilot study with four animals combined with algetic behaviors described for equines. After content validation, the scale was evaluated in 40 other donkeys by three blinded and one reference evaluator, by means of edited videos referring to the preoperative and postoperative periods: before anesthesia, 3–4 h after recovery from anesthesia, 5–6 h after recovery from anesthesia (2 h after analgesia with flunixin—1.1 mg/kg, dipyrone—10 mg/kg, and morphine—0.2 mg/kg) IV, and 24 h after recovery. Content validity, sensitivity, specificity, and responsiveness of behaviors were investigated to refine the scale. Intra- and inter-evaluator reliabilities were investigated by the weighted kappa coefficient, criterion validity by comparing the scale with the visual analog scale (VAS), internal consistency by Cronbach's α coefficient, item-total correlation by the Spearman coefficient, and intervention point for rescue analgesic by the receiver operating characteristics curve and Youden index. The scale showed very good intra-evaluator reliability (0.88–0.96), good to moderate (0.56–0.66) inter-evaluator reliability, responsiveness for all items, good criterion validity vs. VAS (0.75), acceptable internal consistency (0.64), adequate item-total correlation, except for head position and direction, and according to the principal component analysis, good association among items. The accuracy of the point for rescue analgesic was excellent (area under the curve = 0.91). The rescue analgesic score was ≥ 4 of 11 points. The scale can diagnose and quantify acute pain in donkeys submitted to castration, as the instrument is reliable and valid, with a defined intervention analgesic score.
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spelling Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeysanalgesiaanimal behaviorcastrationequineswelfareThis study aimed to validate a scale for assessing acute pain in donkeys. Forty-four adult donkeys underwent castration after sedation with intravenous (IV) xylazine, induction with guaifenesin and thiopental IV, local anesthetic block, and maintenance with isoflurane. The scale was constructed from a pilot study with four animals combined with algetic behaviors described for equines. After content validation, the scale was evaluated in 40 other donkeys by three blinded and one reference evaluator, by means of edited videos referring to the preoperative and postoperative periods: before anesthesia, 3–4 h after recovery from anesthesia, 5–6 h after recovery from anesthesia (2 h after analgesia with flunixin—1.1 mg/kg, dipyrone—10 mg/kg, and morphine—0.2 mg/kg) IV, and 24 h after recovery. Content validity, sensitivity, specificity, and responsiveness of behaviors were investigated to refine the scale. Intra- and inter-evaluator reliabilities were investigated by the weighted kappa coefficient, criterion validity by comparing the scale with the visual analog scale (VAS), internal consistency by Cronbach's α coefficient, item-total correlation by the Spearman coefficient, and intervention point for rescue analgesic by the receiver operating characteristics curve and Youden index. The scale showed very good intra-evaluator reliability (0.88–0.96), good to moderate (0.56–0.66) inter-evaluator reliability, responsiveness for all items, good criterion validity vs. VAS (0.75), acceptable internal consistency (0.64), adequate item-total correlation, except for head position and direction, and according to the principal component analysis, good association among items. The accuracy of the point for rescue analgesic was excellent (area under the curve = 0.91). The rescue analgesic score was ≥ 4 of 11 points. The scale can diagnose and quantify acute pain in donkeys submitted to castration, as the instrument is reliable and valid, with a defined intervention analgesic score.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Animal Sciences Semi-Árido Federal Rural University (UFERSA)Department of Anatomy Pathology and Veterinary Clinics Federal University of Bahia (UFBA)Department of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science São Paulo State University (UNESP)Department of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science São Paulo State University (UNESP)FAPESP: 2017/12815-0Semi-Árido Federal Rural University (UFERSA)Universidade Federal da Bahia (UFBA)Universidade Estadual Paulista (UNESP)Oliveira, Maria Gláucia Carlos dePaula, Valéria Veras deMouta, Andressa NunesLima, Isabelle de OliveiraMacêdo, Luã Barbalho deNunes, Talyta LinsTrindade, Pedro Henrique Esteves [UNESP]Luna, Stelio Pacca Loureiro [UNESP]2022-04-29T08:30:09Z2022-04-29T08:30:09Z2021-06-11info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3389/fvets.2021.671330Frontiers in Veterinary Science, v. 8.2297-1769http://hdl.handle.net/11449/22905910.3389/fvets.2021.6713302-s2.0-85108878512Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFrontiers in Veterinary Scienceinfo:eu-repo/semantics/openAccess2024-09-09T14:01:20Zoai:repositorio.unesp.br:11449/229059Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-09T14:01:20Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys
title Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys
spellingShingle Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys
Oliveira, Maria Gláucia Carlos de
analgesia
animal behavior
castration
equines
welfare
title_short Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys
title_full Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys
title_fullStr Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys
title_full_unstemmed Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys
title_sort Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys
author Oliveira, Maria Gláucia Carlos de
author_facet Oliveira, Maria Gláucia Carlos de
Paula, Valéria Veras de
Mouta, Andressa Nunes
Lima, Isabelle de Oliveira
Macêdo, Luã Barbalho de
Nunes, Talyta Lins
Trindade, Pedro Henrique Esteves [UNESP]
Luna, Stelio Pacca Loureiro [UNESP]
author_role author
author2 Paula, Valéria Veras de
Mouta, Andressa Nunes
Lima, Isabelle de Oliveira
Macêdo, Luã Barbalho de
Nunes, Talyta Lins
Trindade, Pedro Henrique Esteves [UNESP]
Luna, Stelio Pacca Loureiro [UNESP]
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Semi-Árido Federal Rural University (UFERSA)
Universidade Federal da Bahia (UFBA)
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Oliveira, Maria Gláucia Carlos de
Paula, Valéria Veras de
Mouta, Andressa Nunes
Lima, Isabelle de Oliveira
Macêdo, Luã Barbalho de
Nunes, Talyta Lins
Trindade, Pedro Henrique Esteves [UNESP]
Luna, Stelio Pacca Loureiro [UNESP]
dc.subject.por.fl_str_mv analgesia
animal behavior
castration
equines
welfare
topic analgesia
animal behavior
castration
equines
welfare
description This study aimed to validate a scale for assessing acute pain in donkeys. Forty-four adult donkeys underwent castration after sedation with intravenous (IV) xylazine, induction with guaifenesin and thiopental IV, local anesthetic block, and maintenance with isoflurane. The scale was constructed from a pilot study with four animals combined with algetic behaviors described for equines. After content validation, the scale was evaluated in 40 other donkeys by three blinded and one reference evaluator, by means of edited videos referring to the preoperative and postoperative periods: before anesthesia, 3–4 h after recovery from anesthesia, 5–6 h after recovery from anesthesia (2 h after analgesia with flunixin—1.1 mg/kg, dipyrone—10 mg/kg, and morphine—0.2 mg/kg) IV, and 24 h after recovery. Content validity, sensitivity, specificity, and responsiveness of behaviors were investigated to refine the scale. Intra- and inter-evaluator reliabilities were investigated by the weighted kappa coefficient, criterion validity by comparing the scale with the visual analog scale (VAS), internal consistency by Cronbach's α coefficient, item-total correlation by the Spearman coefficient, and intervention point for rescue analgesic by the receiver operating characteristics curve and Youden index. The scale showed very good intra-evaluator reliability (0.88–0.96), good to moderate (0.56–0.66) inter-evaluator reliability, responsiveness for all items, good criterion validity vs. VAS (0.75), acceptable internal consistency (0.64), adequate item-total correlation, except for head position and direction, and according to the principal component analysis, good association among items. The accuracy of the point for rescue analgesic was excellent (area under the curve = 0.91). The rescue analgesic score was ≥ 4 of 11 points. The scale can diagnose and quantify acute pain in donkeys submitted to castration, as the instrument is reliable and valid, with a defined intervention analgesic score.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-11
2022-04-29T08:30:09Z
2022-04-29T08:30:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3389/fvets.2021.671330
Frontiers in Veterinary Science, v. 8.
2297-1769
http://hdl.handle.net/11449/229059
10.3389/fvets.2021.671330
2-s2.0-85108878512
url http://dx.doi.org/10.3389/fvets.2021.671330
http://hdl.handle.net/11449/229059
identifier_str_mv Frontiers in Veterinary Science, v. 8.
2297-1769
10.3389/fvets.2021.671330
2-s2.0-85108878512
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Frontiers in Veterinary Science
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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