Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3389/fvets.2021.671330 http://hdl.handle.net/11449/229059 |
Resumo: | This study aimed to validate a scale for assessing acute pain in donkeys. Forty-four adult donkeys underwent castration after sedation with intravenous (IV) xylazine, induction with guaifenesin and thiopental IV, local anesthetic block, and maintenance with isoflurane. The scale was constructed from a pilot study with four animals combined with algetic behaviors described for equines. After content validation, the scale was evaluated in 40 other donkeys by three blinded and one reference evaluator, by means of edited videos referring to the preoperative and postoperative periods: before anesthesia, 3–4 h after recovery from anesthesia, 5–6 h after recovery from anesthesia (2 h after analgesia with flunixin—1.1 mg/kg, dipyrone—10 mg/kg, and morphine—0.2 mg/kg) IV, and 24 h after recovery. Content validity, sensitivity, specificity, and responsiveness of behaviors were investigated to refine the scale. Intra- and inter-evaluator reliabilities were investigated by the weighted kappa coefficient, criterion validity by comparing the scale with the visual analog scale (VAS), internal consistency by Cronbach's α coefficient, item-total correlation by the Spearman coefficient, and intervention point for rescue analgesic by the receiver operating characteristics curve and Youden index. The scale showed very good intra-evaluator reliability (0.88–0.96), good to moderate (0.56–0.66) inter-evaluator reliability, responsiveness for all items, good criterion validity vs. VAS (0.75), acceptable internal consistency (0.64), adequate item-total correlation, except for head position and direction, and according to the principal component analysis, good association among items. The accuracy of the point for rescue analgesic was excellent (area under the curve = 0.91). The rescue analgesic score was ≥ 4 of 11 points. The scale can diagnose and quantify acute pain in donkeys submitted to castration, as the instrument is reliable and valid, with a defined intervention analgesic score. |
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Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeysanalgesiaanimal behaviorcastrationequineswelfareThis study aimed to validate a scale for assessing acute pain in donkeys. Forty-four adult donkeys underwent castration after sedation with intravenous (IV) xylazine, induction with guaifenesin and thiopental IV, local anesthetic block, and maintenance with isoflurane. The scale was constructed from a pilot study with four animals combined with algetic behaviors described for equines. After content validation, the scale was evaluated in 40 other donkeys by three blinded and one reference evaluator, by means of edited videos referring to the preoperative and postoperative periods: before anesthesia, 3–4 h after recovery from anesthesia, 5–6 h after recovery from anesthesia (2 h after analgesia with flunixin—1.1 mg/kg, dipyrone—10 mg/kg, and morphine—0.2 mg/kg) IV, and 24 h after recovery. Content validity, sensitivity, specificity, and responsiveness of behaviors were investigated to refine the scale. Intra- and inter-evaluator reliabilities were investigated by the weighted kappa coefficient, criterion validity by comparing the scale with the visual analog scale (VAS), internal consistency by Cronbach's α coefficient, item-total correlation by the Spearman coefficient, and intervention point for rescue analgesic by the receiver operating characteristics curve and Youden index. The scale showed very good intra-evaluator reliability (0.88–0.96), good to moderate (0.56–0.66) inter-evaluator reliability, responsiveness for all items, good criterion validity vs. VAS (0.75), acceptable internal consistency (0.64), adequate item-total correlation, except for head position and direction, and according to the principal component analysis, good association among items. The accuracy of the point for rescue analgesic was excellent (area under the curve = 0.91). The rescue analgesic score was ≥ 4 of 11 points. The scale can diagnose and quantify acute pain in donkeys submitted to castration, as the instrument is reliable and valid, with a defined intervention analgesic score.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Animal Sciences Semi-Árido Federal Rural University (UFERSA)Department of Anatomy Pathology and Veterinary Clinics Federal University of Bahia (UFBA)Department of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science São Paulo State University (UNESP)Department of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science São Paulo State University (UNESP)FAPESP: 2017/12815-0Semi-Árido Federal Rural University (UFERSA)Universidade Federal da Bahia (UFBA)Universidade Estadual Paulista (UNESP)Oliveira, Maria Gláucia Carlos dePaula, Valéria Veras deMouta, Andressa NunesLima, Isabelle de OliveiraMacêdo, Luã Barbalho deNunes, Talyta LinsTrindade, Pedro Henrique Esteves [UNESP]Luna, Stelio Pacca Loureiro [UNESP]2022-04-29T08:30:09Z2022-04-29T08:30:09Z2021-06-11info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3389/fvets.2021.671330Frontiers in Veterinary Science, v. 8.2297-1769http://hdl.handle.net/11449/22905910.3389/fvets.2021.6713302-s2.0-85108878512Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFrontiers in Veterinary Scienceinfo:eu-repo/semantics/openAccess2024-09-09T14:01:20Zoai:repositorio.unesp.br:11449/229059Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-09T14:01:20Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys |
title |
Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys |
spellingShingle |
Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys Oliveira, Maria Gláucia Carlos de analgesia animal behavior castration equines welfare |
title_short |
Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys |
title_full |
Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys |
title_fullStr |
Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys |
title_full_unstemmed |
Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys |
title_sort |
Validation of the Donkey Pain Scale (DOPS) for Assessing Postoperative Pain in Donkeys |
author |
Oliveira, Maria Gláucia Carlos de |
author_facet |
Oliveira, Maria Gláucia Carlos de Paula, Valéria Veras de Mouta, Andressa Nunes Lima, Isabelle de Oliveira Macêdo, Luã Barbalho de Nunes, Talyta Lins Trindade, Pedro Henrique Esteves [UNESP] Luna, Stelio Pacca Loureiro [UNESP] |
author_role |
author |
author2 |
Paula, Valéria Veras de Mouta, Andressa Nunes Lima, Isabelle de Oliveira Macêdo, Luã Barbalho de Nunes, Talyta Lins Trindade, Pedro Henrique Esteves [UNESP] Luna, Stelio Pacca Loureiro [UNESP] |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Semi-Árido Federal Rural University (UFERSA) Universidade Federal da Bahia (UFBA) Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Oliveira, Maria Gláucia Carlos de Paula, Valéria Veras de Mouta, Andressa Nunes Lima, Isabelle de Oliveira Macêdo, Luã Barbalho de Nunes, Talyta Lins Trindade, Pedro Henrique Esteves [UNESP] Luna, Stelio Pacca Loureiro [UNESP] |
dc.subject.por.fl_str_mv |
analgesia animal behavior castration equines welfare |
topic |
analgesia animal behavior castration equines welfare |
description |
This study aimed to validate a scale for assessing acute pain in donkeys. Forty-four adult donkeys underwent castration after sedation with intravenous (IV) xylazine, induction with guaifenesin and thiopental IV, local anesthetic block, and maintenance with isoflurane. The scale was constructed from a pilot study with four animals combined with algetic behaviors described for equines. After content validation, the scale was evaluated in 40 other donkeys by three blinded and one reference evaluator, by means of edited videos referring to the preoperative and postoperative periods: before anesthesia, 3–4 h after recovery from anesthesia, 5–6 h after recovery from anesthesia (2 h after analgesia with flunixin—1.1 mg/kg, dipyrone—10 mg/kg, and morphine—0.2 mg/kg) IV, and 24 h after recovery. Content validity, sensitivity, specificity, and responsiveness of behaviors were investigated to refine the scale. Intra- and inter-evaluator reliabilities were investigated by the weighted kappa coefficient, criterion validity by comparing the scale with the visual analog scale (VAS), internal consistency by Cronbach's α coefficient, item-total correlation by the Spearman coefficient, and intervention point for rescue analgesic by the receiver operating characteristics curve and Youden index. The scale showed very good intra-evaluator reliability (0.88–0.96), good to moderate (0.56–0.66) inter-evaluator reliability, responsiveness for all items, good criterion validity vs. VAS (0.75), acceptable internal consistency (0.64), adequate item-total correlation, except for head position and direction, and according to the principal component analysis, good association among items. The accuracy of the point for rescue analgesic was excellent (area under the curve = 0.91). The rescue analgesic score was ≥ 4 of 11 points. The scale can diagnose and quantify acute pain in donkeys submitted to castration, as the instrument is reliable and valid, with a defined intervention analgesic score. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-11 2022-04-29T08:30:09Z 2022-04-29T08:30:09Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3389/fvets.2021.671330 Frontiers in Veterinary Science, v. 8. 2297-1769 http://hdl.handle.net/11449/229059 10.3389/fvets.2021.671330 2-s2.0-85108878512 |
url |
http://dx.doi.org/10.3389/fvets.2021.671330 http://hdl.handle.net/11449/229059 |
identifier_str_mv |
Frontiers in Veterinary Science, v. 8. 2297-1769 10.3389/fvets.2021.671330 2-s2.0-85108878512 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Frontiers in Veterinary Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
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1813546540658065408 |