Ethyl carbamate analysis in german fruit spirits and brazilian sugarcane spirits (cachaça): improved sample cleanup with automated parallel evaporation

Detalhes bibliográficos
Autor(a) principal: Lachenmeier, Dirk W.
Data de Publicação: 2009
Outros Autores: Kuballa, Thomas, Lima, Maria C. P. [UNESP], Nóbrega, Ian C. C., Kerr-Corrêa, Florence [UNESP], Kanteres, Fotis, Rehm, Jürgen
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/225625
Resumo: The analysis of alcoholic beverages for the important carcinogenic con-taminant ethyl carbamate is very time-consuming and expensive. Due to possible matrix interferences, sample cleanup using diatomaceous earth (Extrelut) columns is required prior to gas chromatographic and mass spectrometric measurement. A limiting step in this process is the rotary evaporation of the eluate containing the analyte in organic solvents, which is currently conducted manually and requires approximately 20-30 min per sample. This paper introduces the use of a parallel evaporation device for ethyl carbamate analysis, which allows for the simultaneous evaporation of 12 samples to a specified residual volume without manual intervention. A more efficient and less expensive analy-sis is therefore possible. The method validation showed no differences between the fully-automated parallel evaporation and the manual opera-tion. The applicability was proven by analyzing authentic spirit samples from Germany, Canada and Brazil. It is interesting to note that Brazilian cachaças had a relatively high incidence for ethyl carbamate contamina-tion (55 % of all samples were above 0.15 mg/l), which may be of public health relevance and requires further evaluation.
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spelling Ethyl carbamate analysis in german fruit spirits and brazilian sugarcane spirits (cachaça): improved sample cleanup with automated parallel evaporationThe analysis of alcoholic beverages for the important carcinogenic con-taminant ethyl carbamate is very time-consuming and expensive. Due to possible matrix interferences, sample cleanup using diatomaceous earth (Extrelut) columns is required prior to gas chromatographic and mass spectrometric measurement. A limiting step in this process is the rotary evaporation of the eluate containing the analyte in organic solvents, which is currently conducted manually and requires approximately 20-30 min per sample. This paper introduces the use of a parallel evaporation device for ethyl carbamate analysis, which allows for the simultaneous evaporation of 12 samples to a specified residual volume without manual intervention. A more efficient and less expensive analy-sis is therefore possible. The method validation showed no differences between the fully-automated parallel evaporation and the manual opera-tion. The applicability was proven by analyzing authentic spirit samples from Germany, Canada and Brazil. It is interesting to note that Brazilian cachaças had a relatively high incidence for ethyl carbamate contamina-tion (55 % of all samples were above 0.15 mg/l), which may be of public health relevance and requires further evaluation.Chemisches und Veterinäruntersuchungsamt (CVUA) Karlsruhe, Weissenburger Str. 3, D-76187 KarlsruheDepartamento de Neurologia, Psicologia e Psiquiatria Botucatu Medical School UNESP São Paulo State University, CP 540 -Distrito Rubiao Junior, 18618-970 Botucatu, São PauloUniversidade Federal Rural de Pernambuco Programa de Pós-graduação em Ciência e Tecnologia de Alimentos, CEP 52171-900 Recife, PECentre for Addiction and Mental Health (CAMH), 33 Russell Street, Toronto, ON M5S 2S1Dalla Lana School of Public Health University of Toronto, 55 College Street, Toronto, ON M5T 3M7Institute for Clinical Psychology and Psychotherapy TU Dresden, Chemnitzer Str. 46, 01187 DresdenDepartamento de Neurologia, Psicologia e Psiquiatria Botucatu Medical School UNESP São Paulo State University, CP 540 -Distrito Rubiao Junior, 18618-970 Botucatu, São PauloChemisches und Veterinäruntersuchungsamt (CVUA) KarlsruheUniversidade Estadual Paulista (UNESP)Programa de Pós-graduação em Ciência e Tecnologia de AlimentosCentre for Addiction and Mental Health (CAMH)University of TorontoTU DresdenLachenmeier, Dirk W.Kuballa, ThomasLima, Maria C. P. [UNESP]Nóbrega, Ian C. C.Kerr-Corrêa, Florence [UNESP]Kanteres, FotisRehm, Jürgen2022-04-28T20:55:52Z2022-04-28T20:55:52Z2009-08-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article507-512Deutsche Lebensmittel-Rundschau, v. 105, n. 8, p. 507-512, 2009.0012-0413http://hdl.handle.net/11449/2256252-s2.0-70349459657Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengDeutsche Lebensmittel-Rundschauinfo:eu-repo/semantics/openAccess2024-08-16T15:46:27Zoai:repositorio.unesp.br:11449/225625Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-16T15:46:27Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Ethyl carbamate analysis in german fruit spirits and brazilian sugarcane spirits (cachaça): improved sample cleanup with automated parallel evaporation
title Ethyl carbamate analysis in german fruit spirits and brazilian sugarcane spirits (cachaça): improved sample cleanup with automated parallel evaporation
spellingShingle Ethyl carbamate analysis in german fruit spirits and brazilian sugarcane spirits (cachaça): improved sample cleanup with automated parallel evaporation
Lachenmeier, Dirk W.
title_short Ethyl carbamate analysis in german fruit spirits and brazilian sugarcane spirits (cachaça): improved sample cleanup with automated parallel evaporation
title_full Ethyl carbamate analysis in german fruit spirits and brazilian sugarcane spirits (cachaça): improved sample cleanup with automated parallel evaporation
title_fullStr Ethyl carbamate analysis in german fruit spirits and brazilian sugarcane spirits (cachaça): improved sample cleanup with automated parallel evaporation
title_full_unstemmed Ethyl carbamate analysis in german fruit spirits and brazilian sugarcane spirits (cachaça): improved sample cleanup with automated parallel evaporation
title_sort Ethyl carbamate analysis in german fruit spirits and brazilian sugarcane spirits (cachaça): improved sample cleanup with automated parallel evaporation
author Lachenmeier, Dirk W.
author_facet Lachenmeier, Dirk W.
Kuballa, Thomas
Lima, Maria C. P. [UNESP]
Nóbrega, Ian C. C.
Kerr-Corrêa, Florence [UNESP]
Kanteres, Fotis
Rehm, Jürgen
author_role author
author2 Kuballa, Thomas
Lima, Maria C. P. [UNESP]
Nóbrega, Ian C. C.
Kerr-Corrêa, Florence [UNESP]
Kanteres, Fotis
Rehm, Jürgen
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Chemisches und Veterinäruntersuchungsamt (CVUA) Karlsruhe
Universidade Estadual Paulista (UNESP)
Programa de Pós-graduação em Ciência e Tecnologia de Alimentos
Centre for Addiction and Mental Health (CAMH)
University of Toronto
TU Dresden
dc.contributor.author.fl_str_mv Lachenmeier, Dirk W.
Kuballa, Thomas
Lima, Maria C. P. [UNESP]
Nóbrega, Ian C. C.
Kerr-Corrêa, Florence [UNESP]
Kanteres, Fotis
Rehm, Jürgen
description The analysis of alcoholic beverages for the important carcinogenic con-taminant ethyl carbamate is very time-consuming and expensive. Due to possible matrix interferences, sample cleanup using diatomaceous earth (Extrelut) columns is required prior to gas chromatographic and mass spectrometric measurement. A limiting step in this process is the rotary evaporation of the eluate containing the analyte in organic solvents, which is currently conducted manually and requires approximately 20-30 min per sample. This paper introduces the use of a parallel evaporation device for ethyl carbamate analysis, which allows for the simultaneous evaporation of 12 samples to a specified residual volume without manual intervention. A more efficient and less expensive analy-sis is therefore possible. The method validation showed no differences between the fully-automated parallel evaporation and the manual opera-tion. The applicability was proven by analyzing authentic spirit samples from Germany, Canada and Brazil. It is interesting to note that Brazilian cachaças had a relatively high incidence for ethyl carbamate contamina-tion (55 % of all samples were above 0.15 mg/l), which may be of public health relevance and requires further evaluation.
publishDate 2009
dc.date.none.fl_str_mv 2009-08-01
2022-04-28T20:55:52Z
2022-04-28T20:55:52Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Deutsche Lebensmittel-Rundschau, v. 105, n. 8, p. 507-512, 2009.
0012-0413
http://hdl.handle.net/11449/225625
2-s2.0-70349459657
identifier_str_mv Deutsche Lebensmittel-Rundschau, v. 105, n. 8, p. 507-512, 2009.
0012-0413
2-s2.0-70349459657
url http://hdl.handle.net/11449/225625
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Deutsche Lebensmittel-Rundschau
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 507-512
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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