Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.colsurfa.2022.128721 http://hdl.handle.net/11449/223673 |
Resumo: | Astrocaryum vulgare is an Amazon palm species, popularly known as tucumã. A. vulgare oil has diverse biological purposes, but low solubility in water. Nanoemulsions provide a solution to this problem. This study aimed to evaluate the influence of different surfactants on the development of nanoemulsions. To determine the hydrophilic-lipophilic balance (HLB), the influence of different surfactants on nanoemulsification was determined, the region of nanoemulsion formation on the pseudo-ternary phase diagram was analyzed, nanoemulsions were characterized, and the best candidate was subjected to stability assessment. The HLB was 14, and PPG-5-Ceteth-20 and sorbitan oleate were selected as surfactants. The nanoemulsion had a droplet size of 174.1 nm, a polydispersity index of 0.295, and a zeta potential of 20.7. A. vulgare oil is used in the Amazon for countless pharmaceutical applications. We demonstrate the impact of the chemical structure of surfactants, resulting in the formation of nanoemulsions containing A. vulgare oil. |
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Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm speciesAmazonLow energy methodNanoemulsionSurfactantsTucumãAstrocaryum vulgare is an Amazon palm species, popularly known as tucumã. A. vulgare oil has diverse biological purposes, but low solubility in water. Nanoemulsions provide a solution to this problem. This study aimed to evaluate the influence of different surfactants on the development of nanoemulsions. To determine the hydrophilic-lipophilic balance (HLB), the influence of different surfactants on nanoemulsification was determined, the region of nanoemulsion formation on the pseudo-ternary phase diagram was analyzed, nanoemulsions were characterized, and the best candidate was subjected to stability assessment. The HLB was 14, and PPG-5-Ceteth-20 and sorbitan oleate were selected as surfactants. The nanoemulsion had a droplet size of 174.1 nm, a polydispersity index of 0.295, and a zeta potential of 20.7. A. vulgare oil is used in the Amazon for countless pharmaceutical applications. We demonstrate the impact of the chemical structure of surfactants, resulting in the formation of nanoemulsions containing A. vulgare oil.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)São Paulo State University (Unesp) School of Pharmaceutical Science, São PauloUniversity of Valencia Department of Pharmacy and Pharmaceutical TechnologySão Paulo State University (Unesp) School of Pharmaceutical Science, São PauloCNPq: 130611/2019–0Universidade Estadual Paulista (UNESP)University of ValenciaAlmeida, Fernanda [UNESP]Corrêa, Marcos [UNESP]Zaera, Ana MeleroGarrigues, TeresaIsaac, Vera [UNESP]2022-04-28T19:52:03Z2022-04-28T19:52:03Z2022-06-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.colsurfa.2022.128721Colloids and Surfaces A: Physicochemical and Engineering Aspects, v. 643.1873-43590927-7757http://hdl.handle.net/11449/22367310.1016/j.colsurfa.2022.1287212-s2.0-85126568542Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengColloids and Surfaces A: Physicochemical and Engineering Aspectsinfo:eu-repo/semantics/openAccess2022-04-28T19:52:03Zoai:repositorio.unesp.br:11449/223673Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:22:19.016662Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species |
title |
Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species |
spellingShingle |
Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species Almeida, Fernanda [UNESP] Amazon Low energy method Nanoemulsion Surfactants Tucumã |
title_short |
Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species |
title_full |
Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species |
title_fullStr |
Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species |
title_full_unstemmed |
Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species |
title_sort |
Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species |
author |
Almeida, Fernanda [UNESP] |
author_facet |
Almeida, Fernanda [UNESP] Corrêa, Marcos [UNESP] Zaera, Ana Melero Garrigues, Teresa Isaac, Vera [UNESP] |
author_role |
author |
author2 |
Corrêa, Marcos [UNESP] Zaera, Ana Melero Garrigues, Teresa Isaac, Vera [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) University of Valencia |
dc.contributor.author.fl_str_mv |
Almeida, Fernanda [UNESP] Corrêa, Marcos [UNESP] Zaera, Ana Melero Garrigues, Teresa Isaac, Vera [UNESP] |
dc.subject.por.fl_str_mv |
Amazon Low energy method Nanoemulsion Surfactants Tucumã |
topic |
Amazon Low energy method Nanoemulsion Surfactants Tucumã |
description |
Astrocaryum vulgare is an Amazon palm species, popularly known as tucumã. A. vulgare oil has diverse biological purposes, but low solubility in water. Nanoemulsions provide a solution to this problem. This study aimed to evaluate the influence of different surfactants on the development of nanoemulsions. To determine the hydrophilic-lipophilic balance (HLB), the influence of different surfactants on nanoemulsification was determined, the region of nanoemulsion formation on the pseudo-ternary phase diagram was analyzed, nanoemulsions were characterized, and the best candidate was subjected to stability assessment. The HLB was 14, and PPG-5-Ceteth-20 and sorbitan oleate were selected as surfactants. The nanoemulsion had a droplet size of 174.1 nm, a polydispersity index of 0.295, and a zeta potential of 20.7. A. vulgare oil is used in the Amazon for countless pharmaceutical applications. We demonstrate the impact of the chemical structure of surfactants, resulting in the formation of nanoemulsions containing A. vulgare oil. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-04-28T19:52:03Z 2022-04-28T19:52:03Z 2022-06-20 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.colsurfa.2022.128721 Colloids and Surfaces A: Physicochemical and Engineering Aspects, v. 643. 1873-4359 0927-7757 http://hdl.handle.net/11449/223673 10.1016/j.colsurfa.2022.128721 2-s2.0-85126568542 |
url |
http://dx.doi.org/10.1016/j.colsurfa.2022.128721 http://hdl.handle.net/11449/223673 |
identifier_str_mv |
Colloids and Surfaces A: Physicochemical and Engineering Aspects, v. 643. 1873-4359 0927-7757 10.1016/j.colsurfa.2022.128721 2-s2.0-85126568542 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Colloids and Surfaces A: Physicochemical and Engineering Aspects |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129314140454912 |