Gill denervation eliminates the barostatic reflex in a neotropical teleost, the tambaqui (Colossoma macropomum)

Detalhes bibliográficos
Autor(a) principal: Armelin, Vinicius Araújo
Data de Publicação: 2016
Outros Autores: Braga, Victor Hugo da Silva [UNESP], Teixeira, Mariana Teodoro [UNESP], Rantin, Francisco Tadeu, Florindo, Luiz Henrique [UNESP], Kalinin, Ana Lúcia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1007/s10695-016-0211-9
http://hdl.handle.net/11449/172602
Resumo: The baroreflex is one of the most important regulators of cardiovascular homeostasis in vertebrates. It begins with the monitoring of arterial pressure by baroreceptors, which constantly provide the central nervous system with afferent information about the status of this variable. Any change in arterial pressure relative to its normal state triggers autonomic responses, which are characterized by an inversely proportional change in heart rate and systemic vascular resistance and which tend to restore pressure normality. Although the baroreceptors have been located in mammals and other terrestrial vertebrates, their location in fish is still not completely clear and remains quite controversial. Thus, the objective of this study was to locate the baroreceptors in a teleost, the Colossoma macropomum. To do so, the occurrence and efficiency of the baroreflex were both analyzed when this mechanism was induced by pressure imbalancements in intact fish (IN), first-gill-denervated fish (G1), and total-gill-denervated fish (G4). The pressure imbalances were initiated through the administration of the α1-adrenergic agonist phenylephrine (100 µg kg−1) and the α1-adrenergic antagonist prazosin (1 mg kg−1). The baroreflex responses were then analyzed using an electrocardiogram that allowed for the measurement of the heart rate, the relationship between pre- and post-pharmacological manipulation heart rates, the time required for maximum chronotropic baroreflex response, and total heart rate variability. The results revealed that the barostatic reflex was attenuated in the G1 group and nonexistent in G4 group, findings which indicate that baroreceptors are exclusively located in the gill arches of C. macropomum.
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spelling Gill denervation eliminates the barostatic reflex in a neotropical teleost, the tambaqui (Colossoma macropomum)BaroreceptorBaroreflexGillsTambaquiTeleostThe baroreflex is one of the most important regulators of cardiovascular homeostasis in vertebrates. It begins with the monitoring of arterial pressure by baroreceptors, which constantly provide the central nervous system with afferent information about the status of this variable. Any change in arterial pressure relative to its normal state triggers autonomic responses, which are characterized by an inversely proportional change in heart rate and systemic vascular resistance and which tend to restore pressure normality. Although the baroreceptors have been located in mammals and other terrestrial vertebrates, their location in fish is still not completely clear and remains quite controversial. Thus, the objective of this study was to locate the baroreceptors in a teleost, the Colossoma macropomum. To do so, the occurrence and efficiency of the baroreflex were both analyzed when this mechanism was induced by pressure imbalancements in intact fish (IN), first-gill-denervated fish (G1), and total-gill-denervated fish (G4). The pressure imbalances were initiated through the administration of the α1-adrenergic agonist phenylephrine (100 µg kg−1) and the α1-adrenergic antagonist prazosin (1 mg kg−1). The baroreflex responses were then analyzed using an electrocardiogram that allowed for the measurement of the heart rate, the relationship between pre- and post-pharmacological manipulation heart rates, the time required for maximum chronotropic baroreflex response, and total heart rate variability. The results revealed that the barostatic reflex was attenuated in the G1 group and nonexistent in G4 group, findings which indicate that baroreceptors are exclusively located in the gill arches of C. macropomum.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Physiological Sciences Federal University of São Carlos (UFSCar), Rodovia Washington Luiz, km 235Department of Zoology and Botany São Paulo State University (UNESP), Rua Cristóvão Colombo, 2265National Institute of Science and Technology in Comparative Physiology (INCT – FAPESP/CNPq)Aquaculture Center (CAUNESP) São Paulo State University (UNESP), Rodovia Prof. Paulo Donato Castellane, n/nDepartment of Zoology and Botany São Paulo State University (UNESP), Rua Cristóvão Colombo, 2265Aquaculture Center (CAUNESP) São Paulo State University (UNESP), Rodovia Prof. Paulo Donato Castellane, n/nUniversidade Federal de São Carlos (UFSCar)Universidade Estadual Paulista (Unesp)National Institute of Science and Technology in Comparative Physiology (INCT – FAPESP/CNPq)Armelin, Vinicius AraújoBraga, Victor Hugo da Silva [UNESP]Teixeira, Mariana Teodoro [UNESP]Rantin, Francisco TadeuFlorindo, Luiz Henrique [UNESP]Kalinin, Ana Lúcia2018-12-11T17:01:18Z2018-12-11T17:01:18Z2016-08-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1213-1224application/pdfhttp://dx.doi.org/10.1007/s10695-016-0211-9Fish Physiology and Biochemistry, v. 42, n. 4, p. 1213-1224, 2016.1573-51680920-1742http://hdl.handle.net/11449/17260210.1007/s10695-016-0211-92-s2.0-849593312862-s2.0-84959331286.pdf2797832406818407Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFish Physiology and Biochemistry0,6900,690info:eu-repo/semantics/openAccess2024-04-09T15:36:52Zoai:repositorio.unesp.br:11449/172602Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:14:42.393293Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Gill denervation eliminates the barostatic reflex in a neotropical teleost, the tambaqui (Colossoma macropomum)
title Gill denervation eliminates the barostatic reflex in a neotropical teleost, the tambaqui (Colossoma macropomum)
spellingShingle Gill denervation eliminates the barostatic reflex in a neotropical teleost, the tambaqui (Colossoma macropomum)
Armelin, Vinicius Araújo
Baroreceptor
Baroreflex
Gills
Tambaqui
Teleost
title_short Gill denervation eliminates the barostatic reflex in a neotropical teleost, the tambaqui (Colossoma macropomum)
title_full Gill denervation eliminates the barostatic reflex in a neotropical teleost, the tambaqui (Colossoma macropomum)
title_fullStr Gill denervation eliminates the barostatic reflex in a neotropical teleost, the tambaqui (Colossoma macropomum)
title_full_unstemmed Gill denervation eliminates the barostatic reflex in a neotropical teleost, the tambaqui (Colossoma macropomum)
title_sort Gill denervation eliminates the barostatic reflex in a neotropical teleost, the tambaqui (Colossoma macropomum)
author Armelin, Vinicius Araújo
author_facet Armelin, Vinicius Araújo
Braga, Victor Hugo da Silva [UNESP]
Teixeira, Mariana Teodoro [UNESP]
Rantin, Francisco Tadeu
Florindo, Luiz Henrique [UNESP]
Kalinin, Ana Lúcia
author_role author
author2 Braga, Victor Hugo da Silva [UNESP]
Teixeira, Mariana Teodoro [UNESP]
Rantin, Francisco Tadeu
Florindo, Luiz Henrique [UNESP]
Kalinin, Ana Lúcia
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Carlos (UFSCar)
Universidade Estadual Paulista (Unesp)
National Institute of Science and Technology in Comparative Physiology (INCT – FAPESP/CNPq)
dc.contributor.author.fl_str_mv Armelin, Vinicius Araújo
Braga, Victor Hugo da Silva [UNESP]
Teixeira, Mariana Teodoro [UNESP]
Rantin, Francisco Tadeu
Florindo, Luiz Henrique [UNESP]
Kalinin, Ana Lúcia
dc.subject.por.fl_str_mv Baroreceptor
Baroreflex
Gills
Tambaqui
Teleost
topic Baroreceptor
Baroreflex
Gills
Tambaqui
Teleost
description The baroreflex is one of the most important regulators of cardiovascular homeostasis in vertebrates. It begins with the monitoring of arterial pressure by baroreceptors, which constantly provide the central nervous system with afferent information about the status of this variable. Any change in arterial pressure relative to its normal state triggers autonomic responses, which are characterized by an inversely proportional change in heart rate and systemic vascular resistance and which tend to restore pressure normality. Although the baroreceptors have been located in mammals and other terrestrial vertebrates, their location in fish is still not completely clear and remains quite controversial. Thus, the objective of this study was to locate the baroreceptors in a teleost, the Colossoma macropomum. To do so, the occurrence and efficiency of the baroreflex were both analyzed when this mechanism was induced by pressure imbalancements in intact fish (IN), first-gill-denervated fish (G1), and total-gill-denervated fish (G4). The pressure imbalances were initiated through the administration of the α1-adrenergic agonist phenylephrine (100 µg kg−1) and the α1-adrenergic antagonist prazosin (1 mg kg−1). The baroreflex responses were then analyzed using an electrocardiogram that allowed for the measurement of the heart rate, the relationship between pre- and post-pharmacological manipulation heart rates, the time required for maximum chronotropic baroreflex response, and total heart rate variability. The results revealed that the barostatic reflex was attenuated in the G1 group and nonexistent in G4 group, findings which indicate that baroreceptors are exclusively located in the gill arches of C. macropomum.
publishDate 2016
dc.date.none.fl_str_mv 2016-08-01
2018-12-11T17:01:18Z
2018-12-11T17:01:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/s10695-016-0211-9
Fish Physiology and Biochemistry, v. 42, n. 4, p. 1213-1224, 2016.
1573-5168
0920-1742
http://hdl.handle.net/11449/172602
10.1007/s10695-016-0211-9
2-s2.0-84959331286
2-s2.0-84959331286.pdf
2797832406818407
url http://dx.doi.org/10.1007/s10695-016-0211-9
http://hdl.handle.net/11449/172602
identifier_str_mv Fish Physiology and Biochemistry, v. 42, n. 4, p. 1213-1224, 2016.
1573-5168
0920-1742
10.1007/s10695-016-0211-9
2-s2.0-84959331286
2-s2.0-84959331286.pdf
2797832406818407
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Fish Physiology and Biochemistry
0,690
0,690
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1213-1224
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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