The genetic diversity of Plasmodium vivax: a review

Detalhes bibliográficos
Autor(a) principal: Souza-Neiras, Wanessa Christina de [UNESP]
Data de Publicação: 2007
Outros Autores: Melo, Luciane Moreno Storti de [UNESP], Machado, Ricardo Luiz Dantas
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S0074-02762007000300002
http://hdl.handle.net/11449/21666
Resumo: The genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.
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spelling The genetic diversity of Plasmodium vivax: a reviewMalariaPlasmodium vivaxGenetic diversityMolecular markersPhylogenyEvolutionThe genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.Universidade Estadual Paulista Instituto de Biociências, Letras e Ciências Exatas Departamento de BiologiaFaculdade de Medicina de São José do Rio Preto (FAMERP) Departamento de Doenças Dermatológicas, Infecciosas e Parasitárias Centro de Investigação de MicrorganismosUniversidade Estadual Paulista Instituto de Biociências, Letras e Ciências Exatas Departamento de BiologiaInstituto Oswaldo Cruz, Ministério da SaúdeUniversidade Estadual Paulista (Unesp)Faculdade de Medicina de São José do Rio Preto (FAMERP)Souza-Neiras, Wanessa Christina de [UNESP]Melo, Luciane Moreno Storti de [UNESP]Machado, Ricardo Luiz Dantas2014-05-20T14:01:21Z2014-05-20T14:01:21Z2007-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article245-254application/pdfhttp://dx.doi.org/10.1590/S0074-02762007000300002Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 102, n. 3, p. 245-254, 2007.0074-0276http://hdl.handle.net/11449/2166610.1590/S0074-02762007000300002S0074-02762007000300002S0074-02762007000300002.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMemórias do Instituto Oswaldo Cruz2.8331,172info:eu-repo/semantics/openAccess2023-12-24T06:16:54Zoai:repositorio.unesp.br:11449/21666Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:10:09.037968Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv The genetic diversity of Plasmodium vivax: a review
title The genetic diversity of Plasmodium vivax: a review
spellingShingle The genetic diversity of Plasmodium vivax: a review
Souza-Neiras, Wanessa Christina de [UNESP]
Malaria
Plasmodium vivax
Genetic diversity
Molecular markers
Phylogeny
Evolution
title_short The genetic diversity of Plasmodium vivax: a review
title_full The genetic diversity of Plasmodium vivax: a review
title_fullStr The genetic diversity of Plasmodium vivax: a review
title_full_unstemmed The genetic diversity of Plasmodium vivax: a review
title_sort The genetic diversity of Plasmodium vivax: a review
author Souza-Neiras, Wanessa Christina de [UNESP]
author_facet Souza-Neiras, Wanessa Christina de [UNESP]
Melo, Luciane Moreno Storti de [UNESP]
Machado, Ricardo Luiz Dantas
author_role author
author2 Melo, Luciane Moreno Storti de [UNESP]
Machado, Ricardo Luiz Dantas
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Faculdade de Medicina de São José do Rio Preto (FAMERP)
dc.contributor.author.fl_str_mv Souza-Neiras, Wanessa Christina de [UNESP]
Melo, Luciane Moreno Storti de [UNESP]
Machado, Ricardo Luiz Dantas
dc.subject.por.fl_str_mv Malaria
Plasmodium vivax
Genetic diversity
Molecular markers
Phylogeny
Evolution
topic Malaria
Plasmodium vivax
Genetic diversity
Molecular markers
Phylogeny
Evolution
description The genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.
publishDate 2007
dc.date.none.fl_str_mv 2007-06-01
2014-05-20T14:01:21Z
2014-05-20T14:01:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0074-02762007000300002
Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 102, n. 3, p. 245-254, 2007.
0074-0276
http://hdl.handle.net/11449/21666
10.1590/S0074-02762007000300002
S0074-02762007000300002
S0074-02762007000300002.pdf
url http://dx.doi.org/10.1590/S0074-02762007000300002
http://hdl.handle.net/11449/21666
identifier_str_mv Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 102, n. 3, p. 245-254, 2007.
0074-0276
10.1590/S0074-02762007000300002
S0074-02762007000300002
S0074-02762007000300002.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Memórias do Instituto Oswaldo Cruz
2.833
1,172
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 245-254
application/pdf
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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