Deuterium Equilibrium Time in Saliva of Newborn Infants
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://journals.lww.com/jpgn/Fulltext/2009/04000/Deuterium_Equilibrium_Time_in_Saliva_of_Newborn.15.aspx# http://hdl.handle.net/11449/17695 |
Resumo: | There is an increasing interest about the use of stable isotopes for body composition analysis in pediatrics. To ensure the success of total body water analysis by the deuterium dilution method, it is fundamental to determine the equilibrium tune (plateau) of deuterium in the body fluid studied.Objectives: We report here the equilibration time of deuterium oxide in the saliva of newborns after oral intake of the isotope.Methods: Twenty healthy term newborn infants, 10 males and 10 females, were analyzed. Saliva was collected from each newborn before the oral administration of a 100 mg/kg dose of deuterium oxide (baseline sample) and then at 1-hour intervals for 5 hours after administration. Deuterium enrichment of saliva was determined by isotope ratio mass spectrometry according to the recommendations of the International Atomic Energy Agency.Results: The plateau time of deuterium in saliva occurred 3 hours after oral administration of the stable isotope.Conclusion: These data are essential for further studies on the body composition of newborn infants. To the best of our knowledge, this is the first study regarding the equilibration time of deuterium in the saliva of term newborns. JPGN 48:471-474, 2009. |
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Repositório Institucional da UNESP |
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Deuterium Equilibrium Time in Saliva of Newborn InfantsBody compositionDeuteriumNewbornSalivaTBWThere is an increasing interest about the use of stable isotopes for body composition analysis in pediatrics. To ensure the success of total body water analysis by the deuterium dilution method, it is fundamental to determine the equilibrium tune (plateau) of deuterium in the body fluid studied.Objectives: We report here the equilibration time of deuterium oxide in the saliva of newborns after oral intake of the isotope.Methods: Twenty healthy term newborn infants, 10 males and 10 females, were analyzed. Saliva was collected from each newborn before the oral administration of a 100 mg/kg dose of deuterium oxide (baseline sample) and then at 1-hour intervals for 5 hours after administration. Deuterium enrichment of saliva was determined by isotope ratio mass spectrometry according to the recommendations of the International Atomic Energy Agency.Results: The plateau time of deuterium in saliva occurred 3 hours after oral administration of the stable isotope.Conclusion: These data are essential for further studies on the body composition of newborn infants. To the best of our knowledge, this is the first study regarding the equilibration time of deuterium in the saliva of term newborns. JPGN 48:471-474, 2009.International Atomic Energy Agency, Nestle NutritionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Univ São Paulo, Dept Pediat, São Paulo, BrazilUniv São Paulo, Lab Mass Spectrometry, Dept Internal Med, São Paulo, BrazilUniv São Paulo, Nutr Course, Sch Med Ribeirao Preto, São Paulo, BrazilIBB UNESP, Dept Phys & Biophys, Stable Isotopes Ctr, São Paulo, BrazilIBB UNESP, Dept Phys & Biophys, Stable Isotopes Ctr, São Paulo, BrazilLippincott Williams & WilkinsUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Marti Traver, Luis AngeloMartinez, Francisco EulogioFerriolli, EduardoMarchini, Julio SergioMonteiro, Jacqueline PontesPfrimer, KarinaMichelin Sanchez, Ana Paulade Oliveira, ThaisDucatti, Carlos [UNESP]Camelo, Jose Simon2014-05-20T13:49:37Z2014-05-20T13:49:37Z2009-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article471-474http://journals.lww.com/jpgn/Fulltext/2009/04000/Deuterium_Equilibrium_Time_in_Saliva_of_Newborn.15.aspx#Journal of Pediatric Gastroenterology and Nutrition. Philadelphia: Lippincott Williams & Wilkins, v. 48, n. 4, p. 471-474, 2009.0277-2116http://hdl.handle.net/11449/17695WOS:0002646716000151030251743943217Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Pediatric Gastroenterology and Nutrition2.7521,376info:eu-repo/semantics/openAccess2021-10-23T11:55:37Zoai:repositorio.unesp.br:11449/17695Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T11:55:37Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Deuterium Equilibrium Time in Saliva of Newborn Infants |
title |
Deuterium Equilibrium Time in Saliva of Newborn Infants |
spellingShingle |
Deuterium Equilibrium Time in Saliva of Newborn Infants Marti Traver, Luis Angelo Body composition Deuterium Newborn Saliva TBW |
title_short |
Deuterium Equilibrium Time in Saliva of Newborn Infants |
title_full |
Deuterium Equilibrium Time in Saliva of Newborn Infants |
title_fullStr |
Deuterium Equilibrium Time in Saliva of Newborn Infants |
title_full_unstemmed |
Deuterium Equilibrium Time in Saliva of Newborn Infants |
title_sort |
Deuterium Equilibrium Time in Saliva of Newborn Infants |
author |
Marti Traver, Luis Angelo |
author_facet |
Marti Traver, Luis Angelo Martinez, Francisco Eulogio Ferriolli, Eduardo Marchini, Julio Sergio Monteiro, Jacqueline Pontes Pfrimer, Karina Michelin Sanchez, Ana Paula de Oliveira, Thais Ducatti, Carlos [UNESP] Camelo, Jose Simon |
author_role |
author |
author2 |
Martinez, Francisco Eulogio Ferriolli, Eduardo Marchini, Julio Sergio Monteiro, Jacqueline Pontes Pfrimer, Karina Michelin Sanchez, Ana Paula de Oliveira, Thais Ducatti, Carlos [UNESP] Camelo, Jose Simon |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Marti Traver, Luis Angelo Martinez, Francisco Eulogio Ferriolli, Eduardo Marchini, Julio Sergio Monteiro, Jacqueline Pontes Pfrimer, Karina Michelin Sanchez, Ana Paula de Oliveira, Thais Ducatti, Carlos [UNESP] Camelo, Jose Simon |
dc.subject.por.fl_str_mv |
Body composition Deuterium Newborn Saliva TBW |
topic |
Body composition Deuterium Newborn Saliva TBW |
description |
There is an increasing interest about the use of stable isotopes for body composition analysis in pediatrics. To ensure the success of total body water analysis by the deuterium dilution method, it is fundamental to determine the equilibrium tune (plateau) of deuterium in the body fluid studied.Objectives: We report here the equilibration time of deuterium oxide in the saliva of newborns after oral intake of the isotope.Methods: Twenty healthy term newborn infants, 10 males and 10 females, were analyzed. Saliva was collected from each newborn before the oral administration of a 100 mg/kg dose of deuterium oxide (baseline sample) and then at 1-hour intervals for 5 hours after administration. Deuterium enrichment of saliva was determined by isotope ratio mass spectrometry according to the recommendations of the International Atomic Energy Agency.Results: The plateau time of deuterium in saliva occurred 3 hours after oral administration of the stable isotope.Conclusion: These data are essential for further studies on the body composition of newborn infants. To the best of our knowledge, this is the first study regarding the equilibration time of deuterium in the saliva of term newborns. JPGN 48:471-474, 2009. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-04-01 2014-05-20T13:49:37Z 2014-05-20T13:49:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://journals.lww.com/jpgn/Fulltext/2009/04000/Deuterium_Equilibrium_Time_in_Saliva_of_Newborn.15.aspx# Journal of Pediatric Gastroenterology and Nutrition. Philadelphia: Lippincott Williams & Wilkins, v. 48, n. 4, p. 471-474, 2009. 0277-2116 http://hdl.handle.net/11449/17695 WOS:000264671600015 1030251743943217 |
url |
http://journals.lww.com/jpgn/Fulltext/2009/04000/Deuterium_Equilibrium_Time_in_Saliva_of_Newborn.15.aspx# http://hdl.handle.net/11449/17695 |
identifier_str_mv |
Journal of Pediatric Gastroenterology and Nutrition. Philadelphia: Lippincott Williams & Wilkins, v. 48, n. 4, p. 471-474, 2009. 0277-2116 WOS:000264671600015 1030251743943217 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Pediatric Gastroenterology and Nutrition 2.752 1,376 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
471-474 |
dc.publisher.none.fl_str_mv |
Lippincott Williams & Wilkins |
publisher.none.fl_str_mv |
Lippincott Williams & Wilkins |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797789840026107904 |