Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
DOI: | 10.1109/ACCESS.2021.3135787 |
Texto Completo: | http://dx.doi.org/10.1109/ACCESS.2021.3135787 http://hdl.handle.net/11449/233937 |
Resumo: | Miranda and Bueno recently demonstrated that chemical hardness could be experimentally measured and used as a chemical reactivity index of electrochemical interfaces. Herein, we applied this reactivity index concept to sense biological targets of medical interest, demonstrating the advantages of using this concept in improving the reproducibility of signal analysis during the construction of analytical curves. An analytical signal was obtained for sensing based on the effective chemical hardness of the quantum capacitive electroactive moieties of the interface, demonstrating advantages for calibration compared with methods based solely on the inverse of capacitance. The clinical value of this concept was demonstrated by studying the biological interaction of paclitaxel withβ -tubulin. |
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Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the InterfaceAnalytical curveCalibration procedureConceptual density functional theoryElectrochemical sensorQuality control and reproducibilityQuantum capacitanceMiranda and Bueno recently demonstrated that chemical hardness could be experimentally measured and used as a chemical reactivity index of electrochemical interfaces. Herein, we applied this reactivity index concept to sense biological targets of medical interest, demonstrating the advantages of using this concept in improving the reproducibility of signal analysis during the construction of analytical curves. An analytical signal was obtained for sensing based on the effective chemical hardness of the quantum capacitive electroactive moieties of the interface, demonstrating advantages for calibration compared with methods based solely on the inverse of capacitance. The clinical value of this concept was demonstrated by studying the biological interaction of paclitaxel withβ -tubulin.Escuela de Física Universidad Industrial de SantanderDepartment of Engineering Physics and Mathematics Universidade Estadual Paulista (UNESP), AraraquaraDepartment of Engineering Physics and Mathematics Universidade Estadual Paulista (UNESP), AraraquaraUniversidad Industrial de SantanderUniversidade Estadual Paulista (UNESP)Corzo, Sandra P.Bueno, Paulo R. [UNESP]Miranda, David A.2022-05-01T11:54:06Z2022-05-01T11:54:06Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article166446-166454http://dx.doi.org/10.1109/ACCESS.2021.3135787IEEE Access, v. 9, p. 166446-166454.2169-3536http://hdl.handle.net/11449/23393710.1109/ACCESS.2021.31357872-s2.0-85121795320Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengIEEE Accessinfo:eu-repo/semantics/openAccess2022-05-01T11:54:06Zoai:repositorio.unesp.br:11449/233937Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:56:59.314271Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface |
title |
Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface |
spellingShingle |
Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface Corzo, Sandra P. Analytical curve Calibration procedure Conceptual density functional theory Electrochemical sensor Quality control and reproducibility Quantum capacitance Corzo, Sandra P. Analytical curve Calibration procedure Conceptual density functional theory Electrochemical sensor Quality control and reproducibility Quantum capacitance |
title_short |
Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface |
title_full |
Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface |
title_fullStr |
Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface |
title_full_unstemmed |
Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface |
title_sort |
Improving the Analytical Reproducibility of Electrochemical Capacitive Sensors Using the Chemical Hardness of the Interface |
author |
Corzo, Sandra P. |
author_facet |
Corzo, Sandra P. Corzo, Sandra P. Bueno, Paulo R. [UNESP] Miranda, David A. Bueno, Paulo R. [UNESP] Miranda, David A. |
author_role |
author |
author2 |
Bueno, Paulo R. [UNESP] Miranda, David A. |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidad Industrial de Santander Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Corzo, Sandra P. Bueno, Paulo R. [UNESP] Miranda, David A. |
dc.subject.por.fl_str_mv |
Analytical curve Calibration procedure Conceptual density functional theory Electrochemical sensor Quality control and reproducibility Quantum capacitance |
topic |
Analytical curve Calibration procedure Conceptual density functional theory Electrochemical sensor Quality control and reproducibility Quantum capacitance |
description |
Miranda and Bueno recently demonstrated that chemical hardness could be experimentally measured and used as a chemical reactivity index of electrochemical interfaces. Herein, we applied this reactivity index concept to sense biological targets of medical interest, demonstrating the advantages of using this concept in improving the reproducibility of signal analysis during the construction of analytical curves. An analytical signal was obtained for sensing based on the effective chemical hardness of the quantum capacitive electroactive moieties of the interface, demonstrating advantages for calibration compared with methods based solely on the inverse of capacitance. The clinical value of this concept was demonstrated by studying the biological interaction of paclitaxel withβ -tubulin. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 2022-05-01T11:54:06Z 2022-05-01T11:54:06Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1109/ACCESS.2021.3135787 IEEE Access, v. 9, p. 166446-166454. 2169-3536 http://hdl.handle.net/11449/233937 10.1109/ACCESS.2021.3135787 2-s2.0-85121795320 |
url |
http://dx.doi.org/10.1109/ACCESS.2021.3135787 http://hdl.handle.net/11449/233937 |
identifier_str_mv |
IEEE Access, v. 9, p. 166446-166454. 2169-3536 10.1109/ACCESS.2021.3135787 2-s2.0-85121795320 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
IEEE Access |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
166446-166454 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1822182361618448384 |
dc.identifier.doi.none.fl_str_mv |
10.1109/ACCESS.2021.3135787 |