Líquen plano bucal versus displasia epitelial: Dificuldades diagnósticas
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/S1808-8694(15)30523-1 http://hdl.handle.net/11449/231903 |
Resumo: | Histopathological diagnosis of oral lichen planus is not easy since some cases of epithelial dysplasia may present traits which are very similar to those from lichen planus. Aim: to compare cell alterations which suggest malignancy present in oral lichen planus with those from epithelial dysplasia. Material and methods: histological cross-sections of oral lichen planus and dysplasia, dyed by hematoxylineosin, were analyzed by means of light microscopy. Results: variance analysis (alpha=5%) revealed a statistically significant difference between the average number of cell alterations in the lichen planus (5.83±1.61) and epithelial dysplasia (4.46±1.26). The chi-squared test did not show statistically significant differences between oral lichen planus and epithelial dysplasia in relation to the following cell alterations: increase in nucleus/cytoplasm ratio, nuclear hyperchromatism, irregular chromatin distribution and enlarged nuclei (p>0.05). Conclusion: Some cell alterations which suggest malignancy present in the oral lichen planus may also be found in epithelial dysplasia, impairing its diagnosis and, consequently, stressing the importance of following these patients in the long run. © Revista Brasileira de Otorrinolaringologia. All Rights reserved. |
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Líquen plano bucal versus displasia epitelial: Dificuldades diagnósticasOral lichen planus versus epithelial dysplasia: Difficulties in diagnosisEpitheliumLichen planusMouth mucosaHistopathological diagnosis of oral lichen planus is not easy since some cases of epithelial dysplasia may present traits which are very similar to those from lichen planus. Aim: to compare cell alterations which suggest malignancy present in oral lichen planus with those from epithelial dysplasia. Material and methods: histological cross-sections of oral lichen planus and dysplasia, dyed by hematoxylineosin, were analyzed by means of light microscopy. Results: variance analysis (alpha=5%) revealed a statistically significant difference between the average number of cell alterations in the lichen planus (5.83±1.61) and epithelial dysplasia (4.46±1.26). The chi-squared test did not show statistically significant differences between oral lichen planus and epithelial dysplasia in relation to the following cell alterations: increase in nucleus/cytoplasm ratio, nuclear hyperchromatism, irregular chromatin distribution and enlarged nuclei (p>0.05). Conclusion: Some cell alterations which suggest malignancy present in the oral lichen planus may also be found in epithelial dysplasia, impairing its diagnosis and, consequently, stressing the importance of following these patients in the long run. © Revista Brasileira de Otorrinolaringologia. All Rights reserved.FOSJC UNESPFOSJC UNESPUniversidade Estadual Paulista (UNESP)De Sousa, Fernando Augusto Cervantes GarciaParadella, Thaís CachutéBrandão, Adriana Aigotti Haberbeck [UNESP]Rosa, Luiz Eduardo Blumer [UNESP]2022-04-29T08:48:08Z2022-04-29T08:48:08Z2009-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article716-720http://dx.doi.org/10.1016/S1808-8694(15)30523-1Brazilian Journal of Otorhinolaryngology, v. 75, n. 5, p. 716-720, 2009.1808-86861808-8694http://hdl.handle.net/11449/23190310.1016/S1808-8694(15)30523-12-s2.0-73449130879Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengporBrazilian Journal of Otorhinolaryngologyinfo:eu-repo/semantics/openAccess2022-04-29T08:48:09Zoai:repositorio.unesp.br:11449/231903Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-29T08:48:09Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Líquen plano bucal versus displasia epitelial: Dificuldades diagnósticas Oral lichen planus versus epithelial dysplasia: Difficulties in diagnosis |
title |
Líquen plano bucal versus displasia epitelial: Dificuldades diagnósticas |
spellingShingle |
Líquen plano bucal versus displasia epitelial: Dificuldades diagnósticas De Sousa, Fernando Augusto Cervantes Garcia Epithelium Lichen planus Mouth mucosa |
title_short |
Líquen plano bucal versus displasia epitelial: Dificuldades diagnósticas |
title_full |
Líquen plano bucal versus displasia epitelial: Dificuldades diagnósticas |
title_fullStr |
Líquen plano bucal versus displasia epitelial: Dificuldades diagnósticas |
title_full_unstemmed |
Líquen plano bucal versus displasia epitelial: Dificuldades diagnósticas |
title_sort |
Líquen plano bucal versus displasia epitelial: Dificuldades diagnósticas |
author |
De Sousa, Fernando Augusto Cervantes Garcia |
author_facet |
De Sousa, Fernando Augusto Cervantes Garcia Paradella, Thaís Cachuté Brandão, Adriana Aigotti Haberbeck [UNESP] Rosa, Luiz Eduardo Blumer [UNESP] |
author_role |
author |
author2 |
Paradella, Thaís Cachuté Brandão, Adriana Aigotti Haberbeck [UNESP] Rosa, Luiz Eduardo Blumer [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
De Sousa, Fernando Augusto Cervantes Garcia Paradella, Thaís Cachuté Brandão, Adriana Aigotti Haberbeck [UNESP] Rosa, Luiz Eduardo Blumer [UNESP] |
dc.subject.por.fl_str_mv |
Epithelium Lichen planus Mouth mucosa |
topic |
Epithelium Lichen planus Mouth mucosa |
description |
Histopathological diagnosis of oral lichen planus is not easy since some cases of epithelial dysplasia may present traits which are very similar to those from lichen planus. Aim: to compare cell alterations which suggest malignancy present in oral lichen planus with those from epithelial dysplasia. Material and methods: histological cross-sections of oral lichen planus and dysplasia, dyed by hematoxylineosin, were analyzed by means of light microscopy. Results: variance analysis (alpha=5%) revealed a statistically significant difference between the average number of cell alterations in the lichen planus (5.83±1.61) and epithelial dysplasia (4.46±1.26). The chi-squared test did not show statistically significant differences between oral lichen planus and epithelial dysplasia in relation to the following cell alterations: increase in nucleus/cytoplasm ratio, nuclear hyperchromatism, irregular chromatin distribution and enlarged nuclei (p>0.05). Conclusion: Some cell alterations which suggest malignancy present in the oral lichen planus may also be found in epithelial dysplasia, impairing its diagnosis and, consequently, stressing the importance of following these patients in the long run. © Revista Brasileira de Otorrinolaringologia. All Rights reserved. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-01-01 2022-04-29T08:48:08Z 2022-04-29T08:48:08Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/S1808-8694(15)30523-1 Brazilian Journal of Otorhinolaryngology, v. 75, n. 5, p. 716-720, 2009. 1808-8686 1808-8694 http://hdl.handle.net/11449/231903 10.1016/S1808-8694(15)30523-1 2-s2.0-73449130879 |
url |
http://dx.doi.org/10.1016/S1808-8694(15)30523-1 http://hdl.handle.net/11449/231903 |
identifier_str_mv |
Brazilian Journal of Otorhinolaryngology, v. 75, n. 5, p. 716-720, 2009. 1808-8686 1808-8694 10.1016/S1808-8694(15)30523-1 2-s2.0-73449130879 |
dc.language.iso.fl_str_mv |
eng por |
language |
eng por |
dc.relation.none.fl_str_mv |
Brazilian Journal of Otorhinolaryngology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
716-720 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799964444311158784 |