Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study

Detalhes bibliográficos
Autor(a) principal: Freire, Ana Paula Coelho Figueira
Data de Publicação: 2022
Outros Autores: Lira, Fabio Santos [UNESP], von Ah Morano, Ana Elisa [UNESP], Pereira, Telmo, Coelho-E-silva, Manuel-João, Caseiro, Armando, Christofaro, Diego Giulliano Destro [UNESP], Júnior, Osmar Marchioto [UNESP], Dorneles, Gilson Pires, Minuzzi, Luciele Guerra [UNESP], Pinho, Ricardo Aurino, de Alencar Silva, Bruna Spolador [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3390/ijerph19042457
http://hdl.handle.net/11449/223487
Resumo: The harmful effects of coronavirus disease 2019 (COVID-19) can reach the autonomic nervous system (ANS) and endothelial function. Therefore, the detrimental multiorgan effects of COVID-19 could be induced by deregulations in ANS that may persist after the acute SARS-CoV-2 infection. Additionally, investigating the differences in ANS response in overweight/obese, and physically inactive participants who had COVID-19 compared to those who did not have the disease is necessary. The aim of the study was to analyze the autonomic function of young adults after mild-to-moderate infection with SARS-CoV-2 and to assess whether body mass index (BMI) and levels of physical activity modulates autonomic function in participants with and without COVID-19. Patients previously infected with SARS-CoV-2 and healthy controls were recruited for this cross-sectional observational study. A general anamnesis was taken, and BMI and physical activity levels were assessed. The ANS was evaluated through heart rate variability. A total of 57 subjects were evaluated. Sympathetic nervous system activity in the post-COVID-19 group was increased (stress index; p = 0.0273). They also presented lower values of parasympathetic activity (p < 0.05). Overweight/obese subjects in the post-COVID-19 group presented significantly lower parasympathetic activity and reduced global variability compared to non-obese in control group (p < 0.05). Physically inactive subjects in the post-COVID-19 group presented significantly higher sympathetic activity than active subjects in the control group. Parasympathetic activity was significantly increased in physically active subjects in the control group compared to the physically inactive post-COVID-19 group (p < 0.05). COVID-19 promotes changes in the ANS of young adults, and these changes are modulated by overweight/obesity and physical activity levels.
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spelling Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID StudyAutonomic nervous systemCOVID-19ExerciseHeart rateObesityThe harmful effects of coronavirus disease 2019 (COVID-19) can reach the autonomic nervous system (ANS) and endothelial function. Therefore, the detrimental multiorgan effects of COVID-19 could be induced by deregulations in ANS that may persist after the acute SARS-CoV-2 infection. Additionally, investigating the differences in ANS response in overweight/obese, and physically inactive participants who had COVID-19 compared to those who did not have the disease is necessary. The aim of the study was to analyze the autonomic function of young adults after mild-to-moderate infection with SARS-CoV-2 and to assess whether body mass index (BMI) and levels of physical activity modulates autonomic function in participants with and without COVID-19. Patients previously infected with SARS-CoV-2 and healthy controls were recruited for this cross-sectional observational study. A general anamnesis was taken, and BMI and physical activity levels were assessed. The ANS was evaluated through heart rate variability. A total of 57 subjects were evaluated. Sympathetic nervous system activity in the post-COVID-19 group was increased (stress index; p = 0.0273). They also presented lower values of parasympathetic activity (p < 0.05). Overweight/obese subjects in the post-COVID-19 group presented significantly lower parasympathetic activity and reduced global variability compared to non-obese in control group (p < 0.05). Physically inactive subjects in the post-COVID-19 group presented significantly higher sympathetic activity than active subjects in the control group. Parasympathetic activity was significantly increased in physically active subjects in the control group compared to the physically inactive post-COVID-19 group (p < 0.05). COVID-19 promotes changes in the ANS of young adults, and these changes are modulated by overweight/obesity and physical activity levels.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Health Sciences Central Washington University EllensburgPhysiotherapy Department Universidade do Oeste Paulista (UNOESTE)Exercise and Immunometabolism Research Group Postgraduate Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP)Polytechnic of Coimbra ESTESC Laboratory Biomedical SciencesMolecular Physical-Chemistry R & D Unit Faculty of Science and Technology University of CoimbraLaboratory for Applied Health Research (LabinSaúde)Faculty of Sport Science and Physiucal Education University of Coimbra CIDAFPostgraduate Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP)Cellular and Molecular Immunology Laboratory Universidade Federal de Ciências da Saúde de Porto AlegreGraduate Program in Health Sciences School of Medicine Pontificia Universidade Catolica do ParanaExercise and Immunometabolism Research Group Postgraduate Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP)Postgraduate Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP)CAPES: 001FAPESP: 2019/25626-6Central Washington University EllensburgUniversidade do Oeste Paulista (UNOESTE)Universidade Estadual Paulista (UNESP)Laboratory Biomedical SciencesUniversity of CoimbraLaboratory for Applied Health Research (LabinSaúde)CIDAFUniversidade Federal de Ciências da Saúde de Porto AlegrePontificia Universidade Catolica do ParanaFreire, Ana Paula Coelho FigueiraLira, Fabio Santos [UNESP]von Ah Morano, Ana Elisa [UNESP]Pereira, TelmoCoelho-E-silva, Manuel-JoãoCaseiro, ArmandoChristofaro, Diego Giulliano Destro [UNESP]Júnior, Osmar Marchioto [UNESP]Dorneles, Gilson PiresMinuzzi, Luciele Guerra [UNESP]Pinho, Ricardo Aurinode Alencar Silva, Bruna Spolador [UNESP]2022-04-28T19:50:55Z2022-04-28T19:50:55Z2022-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/ijerph19042457International Journal of Environmental Research and Public Health, v. 19, n. 4, 2022.1660-46011661-7827http://hdl.handle.net/11449/22348710.3390/ijerph190424572-s2.0-85124900390Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Environmental Research and Public Healthinfo:eu-repo/semantics/openAccess2022-04-28T19:50:55Zoai:repositorio.unesp.br:11449/223487Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:15:24.451869Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study
title Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study
spellingShingle Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study
Freire, Ana Paula Coelho Figueira
Autonomic nervous system
COVID-19
Exercise
Heart rate
Obesity
title_short Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study
title_full Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study
title_fullStr Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study
title_full_unstemmed Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study
title_sort Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study
author Freire, Ana Paula Coelho Figueira
author_facet Freire, Ana Paula Coelho Figueira
Lira, Fabio Santos [UNESP]
von Ah Morano, Ana Elisa [UNESP]
Pereira, Telmo
Coelho-E-silva, Manuel-João
Caseiro, Armando
Christofaro, Diego Giulliano Destro [UNESP]
Júnior, Osmar Marchioto [UNESP]
Dorneles, Gilson Pires
Minuzzi, Luciele Guerra [UNESP]
Pinho, Ricardo Aurino
de Alencar Silva, Bruna Spolador [UNESP]
author_role author
author2 Lira, Fabio Santos [UNESP]
von Ah Morano, Ana Elisa [UNESP]
Pereira, Telmo
Coelho-E-silva, Manuel-João
Caseiro, Armando
Christofaro, Diego Giulliano Destro [UNESP]
Júnior, Osmar Marchioto [UNESP]
Dorneles, Gilson Pires
Minuzzi, Luciele Guerra [UNESP]
Pinho, Ricardo Aurino
de Alencar Silva, Bruna Spolador [UNESP]
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Central Washington University Ellensburg
Universidade do Oeste Paulista (UNOESTE)
Universidade Estadual Paulista (UNESP)
Laboratory Biomedical Sciences
University of Coimbra
Laboratory for Applied Health Research (LabinSaúde)
CIDAF
Universidade Federal de Ciências da Saúde de Porto Alegre
Pontificia Universidade Catolica do Parana
dc.contributor.author.fl_str_mv Freire, Ana Paula Coelho Figueira
Lira, Fabio Santos [UNESP]
von Ah Morano, Ana Elisa [UNESP]
Pereira, Telmo
Coelho-E-silva, Manuel-João
Caseiro, Armando
Christofaro, Diego Giulliano Destro [UNESP]
Júnior, Osmar Marchioto [UNESP]
Dorneles, Gilson Pires
Minuzzi, Luciele Guerra [UNESP]
Pinho, Ricardo Aurino
de Alencar Silva, Bruna Spolador [UNESP]
dc.subject.por.fl_str_mv Autonomic nervous system
COVID-19
Exercise
Heart rate
Obesity
topic Autonomic nervous system
COVID-19
Exercise
Heart rate
Obesity
description The harmful effects of coronavirus disease 2019 (COVID-19) can reach the autonomic nervous system (ANS) and endothelial function. Therefore, the detrimental multiorgan effects of COVID-19 could be induced by deregulations in ANS that may persist after the acute SARS-CoV-2 infection. Additionally, investigating the differences in ANS response in overweight/obese, and physically inactive participants who had COVID-19 compared to those who did not have the disease is necessary. The aim of the study was to analyze the autonomic function of young adults after mild-to-moderate infection with SARS-CoV-2 and to assess whether body mass index (BMI) and levels of physical activity modulates autonomic function in participants with and without COVID-19. Patients previously infected with SARS-CoV-2 and healthy controls were recruited for this cross-sectional observational study. A general anamnesis was taken, and BMI and physical activity levels were assessed. The ANS was evaluated through heart rate variability. A total of 57 subjects were evaluated. Sympathetic nervous system activity in the post-COVID-19 group was increased (stress index; p = 0.0273). They also presented lower values of parasympathetic activity (p < 0.05). Overweight/obese subjects in the post-COVID-19 group presented significantly lower parasympathetic activity and reduced global variability compared to non-obese in control group (p < 0.05). Physically inactive subjects in the post-COVID-19 group presented significantly higher sympathetic activity than active subjects in the control group. Parasympathetic activity was significantly increased in physically active subjects in the control group compared to the physically inactive post-COVID-19 group (p < 0.05). COVID-19 promotes changes in the ANS of young adults, and these changes are modulated by overweight/obesity and physical activity levels.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-28T19:50:55Z
2022-04-28T19:50:55Z
2022-02-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3390/ijerph19042457
International Journal of Environmental Research and Public Health, v. 19, n. 4, 2022.
1660-4601
1661-7827
http://hdl.handle.net/11449/223487
10.3390/ijerph19042457
2-s2.0-85124900390
url http://dx.doi.org/10.3390/ijerph19042457
http://hdl.handle.net/11449/223487
identifier_str_mv International Journal of Environmental Research and Public Health, v. 19, n. 4, 2022.
1660-4601
1661-7827
10.3390/ijerph19042457
2-s2.0-85124900390
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv International Journal of Environmental Research and Public Health
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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