Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/ijerph19042457 http://hdl.handle.net/11449/223487 |
Resumo: | The harmful effects of coronavirus disease 2019 (COVID-19) can reach the autonomic nervous system (ANS) and endothelial function. Therefore, the detrimental multiorgan effects of COVID-19 could be induced by deregulations in ANS that may persist after the acute SARS-CoV-2 infection. Additionally, investigating the differences in ANS response in overweight/obese, and physically inactive participants who had COVID-19 compared to those who did not have the disease is necessary. The aim of the study was to analyze the autonomic function of young adults after mild-to-moderate infection with SARS-CoV-2 and to assess whether body mass index (BMI) and levels of physical activity modulates autonomic function in participants with and without COVID-19. Patients previously infected with SARS-CoV-2 and healthy controls were recruited for this cross-sectional observational study. A general anamnesis was taken, and BMI and physical activity levels were assessed. The ANS was evaluated through heart rate variability. A total of 57 subjects were evaluated. Sympathetic nervous system activity in the post-COVID-19 group was increased (stress index; p = 0.0273). They also presented lower values of parasympathetic activity (p < 0.05). Overweight/obese subjects in the post-COVID-19 group presented significantly lower parasympathetic activity and reduced global variability compared to non-obese in control group (p < 0.05). Physically inactive subjects in the post-COVID-19 group presented significantly higher sympathetic activity than active subjects in the control group. Parasympathetic activity was significantly increased in physically active subjects in the control group compared to the physically inactive post-COVID-19 group (p < 0.05). COVID-19 promotes changes in the ANS of young adults, and these changes are modulated by overweight/obesity and physical activity levels. |
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Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID StudyAutonomic nervous systemCOVID-19ExerciseHeart rateObesityThe harmful effects of coronavirus disease 2019 (COVID-19) can reach the autonomic nervous system (ANS) and endothelial function. Therefore, the detrimental multiorgan effects of COVID-19 could be induced by deregulations in ANS that may persist after the acute SARS-CoV-2 infection. Additionally, investigating the differences in ANS response in overweight/obese, and physically inactive participants who had COVID-19 compared to those who did not have the disease is necessary. The aim of the study was to analyze the autonomic function of young adults after mild-to-moderate infection with SARS-CoV-2 and to assess whether body mass index (BMI) and levels of physical activity modulates autonomic function in participants with and without COVID-19. Patients previously infected with SARS-CoV-2 and healthy controls were recruited for this cross-sectional observational study. A general anamnesis was taken, and BMI and physical activity levels were assessed. The ANS was evaluated through heart rate variability. A total of 57 subjects were evaluated. Sympathetic nervous system activity in the post-COVID-19 group was increased (stress index; p = 0.0273). They also presented lower values of parasympathetic activity (p < 0.05). Overweight/obese subjects in the post-COVID-19 group presented significantly lower parasympathetic activity and reduced global variability compared to non-obese in control group (p < 0.05). Physically inactive subjects in the post-COVID-19 group presented significantly higher sympathetic activity than active subjects in the control group. Parasympathetic activity was significantly increased in physically active subjects in the control group compared to the physically inactive post-COVID-19 group (p < 0.05). COVID-19 promotes changes in the ANS of young adults, and these changes are modulated by overweight/obesity and physical activity levels.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Health Sciences Central Washington University EllensburgPhysiotherapy Department Universidade do Oeste Paulista (UNOESTE)Exercise and Immunometabolism Research Group Postgraduate Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP)Polytechnic of Coimbra ESTESC Laboratory Biomedical SciencesMolecular Physical-Chemistry R & D Unit Faculty of Science and Technology University of CoimbraLaboratory for Applied Health Research (LabinSaúde)Faculty of Sport Science and Physiucal Education University of Coimbra CIDAFPostgraduate Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP)Cellular and Molecular Immunology Laboratory Universidade Federal de Ciências da Saúde de Porto AlegreGraduate Program in Health Sciences School of Medicine Pontificia Universidade Catolica do ParanaExercise and Immunometabolism Research Group Postgraduate Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP)Postgraduate Program in Movement Sciences Department of Physical Education Universidade Estadual Paulista (UNESP)CAPES: 001FAPESP: 2019/25626-6Central Washington University EllensburgUniversidade do Oeste Paulista (UNOESTE)Universidade Estadual Paulista (UNESP)Laboratory Biomedical SciencesUniversity of CoimbraLaboratory for Applied Health Research (LabinSaúde)CIDAFUniversidade Federal de Ciências da Saúde de Porto AlegrePontificia Universidade Catolica do ParanaFreire, Ana Paula Coelho FigueiraLira, Fabio Santos [UNESP]von Ah Morano, Ana Elisa [UNESP]Pereira, TelmoCoelho-E-silva, Manuel-JoãoCaseiro, ArmandoChristofaro, Diego Giulliano Destro [UNESP]Júnior, Osmar Marchioto [UNESP]Dorneles, Gilson PiresMinuzzi, Luciele Guerra [UNESP]Pinho, Ricardo Aurinode Alencar Silva, Bruna Spolador [UNESP]2022-04-28T19:50:55Z2022-04-28T19:50:55Z2022-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/ijerph19042457International Journal of Environmental Research and Public Health, v. 19, n. 4, 2022.1660-46011661-7827http://hdl.handle.net/11449/22348710.3390/ijerph190424572-s2.0-85124900390Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Journal of Environmental Research and Public Healthinfo:eu-repo/semantics/openAccess2022-04-28T19:50:55Zoai:repositorio.unesp.br:11449/223487Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:15:24.451869Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study |
title |
Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study |
spellingShingle |
Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study Freire, Ana Paula Coelho Figueira Autonomic nervous system COVID-19 Exercise Heart rate Obesity |
title_short |
Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study |
title_full |
Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study |
title_fullStr |
Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study |
title_full_unstemmed |
Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study |
title_sort |
Role of Body Mass and Physical Activity in Autonomic Function Modulation on Post-COVID-19 Condition: An Observational Subanalysis of Fit-COVID Study |
author |
Freire, Ana Paula Coelho Figueira |
author_facet |
Freire, Ana Paula Coelho Figueira Lira, Fabio Santos [UNESP] von Ah Morano, Ana Elisa [UNESP] Pereira, Telmo Coelho-E-silva, Manuel-João Caseiro, Armando Christofaro, Diego Giulliano Destro [UNESP] Júnior, Osmar Marchioto [UNESP] Dorneles, Gilson Pires Minuzzi, Luciele Guerra [UNESP] Pinho, Ricardo Aurino de Alencar Silva, Bruna Spolador [UNESP] |
author_role |
author |
author2 |
Lira, Fabio Santos [UNESP] von Ah Morano, Ana Elisa [UNESP] Pereira, Telmo Coelho-E-silva, Manuel-João Caseiro, Armando Christofaro, Diego Giulliano Destro [UNESP] Júnior, Osmar Marchioto [UNESP] Dorneles, Gilson Pires Minuzzi, Luciele Guerra [UNESP] Pinho, Ricardo Aurino de Alencar Silva, Bruna Spolador [UNESP] |
author2_role |
author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Central Washington University Ellensburg Universidade do Oeste Paulista (UNOESTE) Universidade Estadual Paulista (UNESP) Laboratory Biomedical Sciences University of Coimbra Laboratory for Applied Health Research (LabinSaúde) CIDAF Universidade Federal de Ciências da Saúde de Porto Alegre Pontificia Universidade Catolica do Parana |
dc.contributor.author.fl_str_mv |
Freire, Ana Paula Coelho Figueira Lira, Fabio Santos [UNESP] von Ah Morano, Ana Elisa [UNESP] Pereira, Telmo Coelho-E-silva, Manuel-João Caseiro, Armando Christofaro, Diego Giulliano Destro [UNESP] Júnior, Osmar Marchioto [UNESP] Dorneles, Gilson Pires Minuzzi, Luciele Guerra [UNESP] Pinho, Ricardo Aurino de Alencar Silva, Bruna Spolador [UNESP] |
dc.subject.por.fl_str_mv |
Autonomic nervous system COVID-19 Exercise Heart rate Obesity |
topic |
Autonomic nervous system COVID-19 Exercise Heart rate Obesity |
description |
The harmful effects of coronavirus disease 2019 (COVID-19) can reach the autonomic nervous system (ANS) and endothelial function. Therefore, the detrimental multiorgan effects of COVID-19 could be induced by deregulations in ANS that may persist after the acute SARS-CoV-2 infection. Additionally, investigating the differences in ANS response in overweight/obese, and physically inactive participants who had COVID-19 compared to those who did not have the disease is necessary. The aim of the study was to analyze the autonomic function of young adults after mild-to-moderate infection with SARS-CoV-2 and to assess whether body mass index (BMI) and levels of physical activity modulates autonomic function in participants with and without COVID-19. Patients previously infected with SARS-CoV-2 and healthy controls were recruited for this cross-sectional observational study. A general anamnesis was taken, and BMI and physical activity levels were assessed. The ANS was evaluated through heart rate variability. A total of 57 subjects were evaluated. Sympathetic nervous system activity in the post-COVID-19 group was increased (stress index; p = 0.0273). They also presented lower values of parasympathetic activity (p < 0.05). Overweight/obese subjects in the post-COVID-19 group presented significantly lower parasympathetic activity and reduced global variability compared to non-obese in control group (p < 0.05). Physically inactive subjects in the post-COVID-19 group presented significantly higher sympathetic activity than active subjects in the control group. Parasympathetic activity was significantly increased in physically active subjects in the control group compared to the physically inactive post-COVID-19 group (p < 0.05). COVID-19 promotes changes in the ANS of young adults, and these changes are modulated by overweight/obesity and physical activity levels. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-04-28T19:50:55Z 2022-04-28T19:50:55Z 2022-02-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/ijerph19042457 International Journal of Environmental Research and Public Health, v. 19, n. 4, 2022. 1660-4601 1661-7827 http://hdl.handle.net/11449/223487 10.3390/ijerph19042457 2-s2.0-85124900390 |
url |
http://dx.doi.org/10.3390/ijerph19042457 http://hdl.handle.net/11449/223487 |
identifier_str_mv |
International Journal of Environmental Research and Public Health, v. 19, n. 4, 2022. 1660-4601 1661-7827 10.3390/ijerph19042457 2-s2.0-85124900390 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
International Journal of Environmental Research and Public Health |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129043292225536 |