Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxo
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.5433/1679-0359.2013v34n4p1793 http://hdl.handle.net/11449/75873 |
Resumo: | Lymphoma is the most common hematopoietic tumor in dogs and one of the malignant tumors with higher occurrence in this species. It is a great experimental model due to its resemblance with the non-Hodgkin lymphoma in humans. Considering the importance of the overall changes that result from to this kind of neoplastic tumor and those due to polichemotherapy this study aimed to evaluate the absolute leukon count and the total count of CD45+ cells in the blood of 25 dogs with lymphoma. Findings were crosschecked since diagnose and then once weekly during the first eight sessions of the Madison-Wisconsin chemotherapic protocol. Total granulocyte, lymphocyte and monocyte counts obtained from a conventional automatic counter and by flow cytometry were compared. Results did not reveal statistically significant changes between the two techniques. |
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Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxoEvaluation of leukocyte count in dogs with lymphoma submitted to the Madison-Wisconsin protocol by conventional technique and flow cytometryCD45DogLymphomaLymphoma is the most common hematopoietic tumor in dogs and one of the malignant tumors with higher occurrence in this species. It is a great experimental model due to its resemblance with the non-Hodgkin lymphoma in humans. Considering the importance of the overall changes that result from to this kind of neoplastic tumor and those due to polichemotherapy this study aimed to evaluate the absolute leukon count and the total count of CD45+ cells in the blood of 25 dogs with lymphoma. Findings were crosschecked since diagnose and then once weekly during the first eight sessions of the Madison-Wisconsin chemotherapic protocol. Total granulocyte, lymphocyte and monocyte counts obtained from a conventional automatic counter and by flow cytometry were compared. Results did not reveal statistically significant changes between the two techniques.Discente(s) de Doutorado Do Curso em Medicina Veterinária Universidade Estadual Paulista Campus Jaboticabal, PRMedicina Veterinária Universidade Estadual Paulista Campus Jaboticabal, PRDepto de Medicina e Cirurgia Veterinária Universidade Estadual Paulista Campus Jaboticabal, PRDiscente(s) de Doutorado Do Curso em Medicina Veterinária Universidade Estadual Paulista Campus Jaboticabal, PRMedicina Veterinária Universidade Estadual Paulista Campus Jaboticabal, PRDepto de Medicina e Cirurgia Veterinária Universidade Estadual Paulista Campus Jaboticabal, PRUniversidade Estadual Paulista (Unesp)Anai, Letícia Abrahão [UNESP]Dela Coleta, Flávia Eiras [UNESP]Munhoz, Thiago Demarchi [UNESP]Nogueira, Andressa Francisca Silva [UNESP]Semolin, Lívia Maria Souza [UNESP]Vieira, Manuela Cristina [UNESP]Santana, Aureo Evangelista [UNESP]2014-05-27T11:29:54Z2014-05-27T11:29:54Z2013-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1793-1800application/pdfhttp://dx.doi.org/10.5433/1679-0359.2013v34n4p1793Semina:Ciencias Agrarias, v. 34, n. 4, p. 1793-1800, 2013.1676-546X1679-0359http://hdl.handle.net/11449/7587310.5433/1679-0359.2013v34n4p1793WOS:0003282699000312-s2.0-848851326282-s2.0-84885132628.pdf8905659987198068Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporSemina: Ciências Agrárias0.3490,320info:eu-repo/semantics/openAccess2024-06-06T14:10:21Zoai:repositorio.unesp.br:11449/75873Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:29:59.308171Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxo Evaluation of leukocyte count in dogs with lymphoma submitted to the Madison-Wisconsin protocol by conventional technique and flow cytometry |
title |
Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxo |
spellingShingle |
Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxo Anai, Letícia Abrahão [UNESP] CD45 Dog Lymphoma |
title_short |
Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxo |
title_full |
Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxo |
title_fullStr |
Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxo |
title_full_unstemmed |
Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxo |
title_sort |
Avaliação leucocitária de cães com linfoma submetidos ao protocolo de Madison-Wisconsin pela técnica convencional e citometria de fluxo |
author |
Anai, Letícia Abrahão [UNESP] |
author_facet |
Anai, Letícia Abrahão [UNESP] Dela Coleta, Flávia Eiras [UNESP] Munhoz, Thiago Demarchi [UNESP] Nogueira, Andressa Francisca Silva [UNESP] Semolin, Lívia Maria Souza [UNESP] Vieira, Manuela Cristina [UNESP] Santana, Aureo Evangelista [UNESP] |
author_role |
author |
author2 |
Dela Coleta, Flávia Eiras [UNESP] Munhoz, Thiago Demarchi [UNESP] Nogueira, Andressa Francisca Silva [UNESP] Semolin, Lívia Maria Souza [UNESP] Vieira, Manuela Cristina [UNESP] Santana, Aureo Evangelista [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Anai, Letícia Abrahão [UNESP] Dela Coleta, Flávia Eiras [UNESP] Munhoz, Thiago Demarchi [UNESP] Nogueira, Andressa Francisca Silva [UNESP] Semolin, Lívia Maria Souza [UNESP] Vieira, Manuela Cristina [UNESP] Santana, Aureo Evangelista [UNESP] |
dc.subject.por.fl_str_mv |
CD45 Dog Lymphoma |
topic |
CD45 Dog Lymphoma |
description |
Lymphoma is the most common hematopoietic tumor in dogs and one of the malignant tumors with higher occurrence in this species. It is a great experimental model due to its resemblance with the non-Hodgkin lymphoma in humans. Considering the importance of the overall changes that result from to this kind of neoplastic tumor and those due to polichemotherapy this study aimed to evaluate the absolute leukon count and the total count of CD45+ cells in the blood of 25 dogs with lymphoma. Findings were crosschecked since diagnose and then once weekly during the first eight sessions of the Madison-Wisconsin chemotherapic protocol. Total granulocyte, lymphocyte and monocyte counts obtained from a conventional automatic counter and by flow cytometry were compared. Results did not reveal statistically significant changes between the two techniques. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-07-01 2014-05-27T11:29:54Z 2014-05-27T11:29:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.5433/1679-0359.2013v34n4p1793 Semina:Ciencias Agrarias, v. 34, n. 4, p. 1793-1800, 2013. 1676-546X 1679-0359 http://hdl.handle.net/11449/75873 10.5433/1679-0359.2013v34n4p1793 WOS:000328269900031 2-s2.0-84885132628 2-s2.0-84885132628.pdf 8905659987198068 |
url |
http://dx.doi.org/10.5433/1679-0359.2013v34n4p1793 http://hdl.handle.net/11449/75873 |
identifier_str_mv |
Semina:Ciencias Agrarias, v. 34, n. 4, p. 1793-1800, 2013. 1676-546X 1679-0359 10.5433/1679-0359.2013v34n4p1793 WOS:000328269900031 2-s2.0-84885132628 2-s2.0-84885132628.pdf 8905659987198068 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Semina: Ciências Agrárias 0.349 0,320 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1793-1800 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129077708587008 |