Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)

Detalhes bibliográficos
Autor(a) principal: Murakami, M. T. [UNESP]
Data de Publicação: 2009
Outros Autores: Kini, R. M., Arni, R. K. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.2174/092986609789839304
http://hdl.handle.net/11449/225725
Resumo: Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 Å resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered a-neurotoxin possessing a positively charged AChR-binding site. © 2009 Bentham Science Publishers Ltd.
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spelling Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)BucainBungarus candidusCrystal structureThree-finger α-neurotoxinBucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 Å resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered a-neurotoxin possessing a positively charged AChR-binding site. © 2009 Bentham Science Publishers Ltd.Center of Structural and Molecular Biology Department of Physics IBILCE/UNESP, São José do Rio Preto, SPDepartment of Biological Sciences Faculty of Science National University of Singapore, SingaporeDepartment of Biochemistry and Molecular Biology Medical College of Virginia Virginia Commonwealth University, Richmond, VACenter for Applied Toxinology CAT/CEPID Butantan Institute, São Paulo-SPCenter for Structural Molecular Biology Brazilian Synchrotron Light Laboratory, Campinas, SPCenter of Structural and Molecular Biology Department of Physics IBILCE/UNESP, São José do Rio Preto, SPUniversidade Estadual Paulista (UNESP)National University of SingaporeVirginia Commonwealth UniversityButantan InstituteBrazilian Synchrotron Light LaboratoryMurakami, M. T. [UNESP]Kini, R. M.Arni, R. K. [UNESP]2022-04-28T20:59:05Z2022-04-28T20:59:05Z2009-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1473-1477http://dx.doi.org/10.2174/092986609789839304Protein and Peptide Letters, v. 16, n. 12, p. 1473-1477, 2009.0929-8665http://hdl.handle.net/11449/22572510.2174/0929866097898393042-s2.0-73449108823Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengProtein and Peptide Lettersinfo:eu-repo/semantics/openAccess2022-04-28T20:59:05Zoai:repositorio.unesp.br:11449/225725Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T20:59:05Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)
title Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)
spellingShingle Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)
Murakami, M. T. [UNESP]
Bucain
Bungarus candidus
Crystal structure
Three-finger α-neurotoxin
title_short Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)
title_full Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)
title_fullStr Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)
title_full_unstemmed Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)
title_sort Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)
author Murakami, M. T. [UNESP]
author_facet Murakami, M. T. [UNESP]
Kini, R. M.
Arni, R. K. [UNESP]
author_role author
author2 Kini, R. M.
Arni, R. K. [UNESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
National University of Singapore
Virginia Commonwealth University
Butantan Institute
Brazilian Synchrotron Light Laboratory
dc.contributor.author.fl_str_mv Murakami, M. T. [UNESP]
Kini, R. M.
Arni, R. K. [UNESP]
dc.subject.por.fl_str_mv Bucain
Bungarus candidus
Crystal structure
Three-finger α-neurotoxin
topic Bucain
Bungarus candidus
Crystal structure
Three-finger α-neurotoxin
description Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 Å resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered a-neurotoxin possessing a positively charged AChR-binding site. © 2009 Bentham Science Publishers Ltd.
publishDate 2009
dc.date.none.fl_str_mv 2009-12-01
2022-04-28T20:59:05Z
2022-04-28T20:59:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.2174/092986609789839304
Protein and Peptide Letters, v. 16, n. 12, p. 1473-1477, 2009.
0929-8665
http://hdl.handle.net/11449/225725
10.2174/092986609789839304
2-s2.0-73449108823
url http://dx.doi.org/10.2174/092986609789839304
http://hdl.handle.net/11449/225725
identifier_str_mv Protein and Peptide Letters, v. 16, n. 12, p. 1473-1477, 2009.
0929-8665
10.2174/092986609789839304
2-s2.0-73449108823
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Protein and Peptide Letters
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1473-1477
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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