Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.2174/092986609789839304 http://hdl.handle.net/11449/225725 |
Resumo: | Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 Å resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered a-neurotoxin possessing a positively charged AChR-binding site. © 2009 Bentham Science Publishers Ltd. |
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Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)BucainBungarus candidusCrystal structureThree-finger α-neurotoxinBucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 Å resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered a-neurotoxin possessing a positively charged AChR-binding site. © 2009 Bentham Science Publishers Ltd.Center of Structural and Molecular Biology Department of Physics IBILCE/UNESP, São José do Rio Preto, SPDepartment of Biological Sciences Faculty of Science National University of Singapore, SingaporeDepartment of Biochemistry and Molecular Biology Medical College of Virginia Virginia Commonwealth University, Richmond, VACenter for Applied Toxinology CAT/CEPID Butantan Institute, São Paulo-SPCenter for Structural Molecular Biology Brazilian Synchrotron Light Laboratory, Campinas, SPCenter of Structural and Molecular Biology Department of Physics IBILCE/UNESP, São José do Rio Preto, SPUniversidade Estadual Paulista (UNESP)National University of SingaporeVirginia Commonwealth UniversityButantan InstituteBrazilian Synchrotron Light LaboratoryMurakami, M. T. [UNESP]Kini, R. M.Arni, R. K. [UNESP]2022-04-28T20:59:05Z2022-04-28T20:59:05Z2009-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1473-1477http://dx.doi.org/10.2174/092986609789839304Protein and Peptide Letters, v. 16, n. 12, p. 1473-1477, 2009.0929-8665http://hdl.handle.net/11449/22572510.2174/0929866097898393042-s2.0-73449108823Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengProtein and Peptide Lettersinfo:eu-repo/semantics/openAccess2022-04-28T20:59:05Zoai:repositorio.unesp.br:11449/225725Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T20:59:05Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus) |
title |
Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus) |
spellingShingle |
Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus) Murakami, M. T. [UNESP] Bucain Bungarus candidus Crystal structure Three-finger α-neurotoxin |
title_short |
Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus) |
title_full |
Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus) |
title_fullStr |
Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus) |
title_full_unstemmed |
Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus) |
title_sort |
Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus) |
author |
Murakami, M. T. [UNESP] |
author_facet |
Murakami, M. T. [UNESP] Kini, R. M. Arni, R. K. [UNESP] |
author_role |
author |
author2 |
Kini, R. M. Arni, R. K. [UNESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) National University of Singapore Virginia Commonwealth University Butantan Institute Brazilian Synchrotron Light Laboratory |
dc.contributor.author.fl_str_mv |
Murakami, M. T. [UNESP] Kini, R. M. Arni, R. K. [UNESP] |
dc.subject.por.fl_str_mv |
Bucain Bungarus candidus Crystal structure Three-finger α-neurotoxin |
topic |
Bucain Bungarus candidus Crystal structure Three-finger α-neurotoxin |
description |
Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 Å resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered a-neurotoxin possessing a positively charged AChR-binding site. © 2009 Bentham Science Publishers Ltd. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-12-01 2022-04-28T20:59:05Z 2022-04-28T20:59:05Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.2174/092986609789839304 Protein and Peptide Letters, v. 16, n. 12, p. 1473-1477, 2009. 0929-8665 http://hdl.handle.net/11449/225725 10.2174/092986609789839304 2-s2.0-73449108823 |
url |
http://dx.doi.org/10.2174/092986609789839304 http://hdl.handle.net/11449/225725 |
identifier_str_mv |
Protein and Peptide Letters, v. 16, n. 12, p. 1473-1477, 2009. 0929-8665 10.2174/092986609789839304 2-s2.0-73449108823 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Protein and Peptide Letters |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1473-1477 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965680896835584 |