Biological Maturation, Central Adiposity, and Metabolic Risk in Adolescents: A Mediation Analysis
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1089/chi.2016.0042 http://hdl.handle.net/11449/168989 |
Resumo: | Background: Earlier biological maturation has been related to increased metabolic risk. In this study, we verified mediating effects by central adiposity of the relationship between somatic maturity and metabolic risk factors in adolescents. Methods: In a cross-sectional study, 1034 adolescents aged 10-16 years from Londrina/PR/Brazil were evaluated. The age of peak height velocity (PHV) method was used to evaluate somatic maturity. Central adiposity was estimated through waist circumference measurements. Fasting glucose, triglycerides, high-density lipoprotein cholesterol (HDL-C), and blood pressure were measured as metabolic risk indicators. Physical activity (Baecke questionnaire) and cardiorespiratory fitness (20-m shuttle run test) were used as covariates. Results: Except for fasting glucose, waist circumference showed partial or full mediation of the relationship between maturity and the following metabolic risk factors with their respective z-score values: triglycerides (boys =-3.554 vs. girls =-5.031), HDL-C (boys = +5.300 vs. girls = +5.905), systolic blood pressure (boys =-3.540 vs. girls =-3.763), diastolic blood pressure (boys =-2.967 vs. girls =-3.264), and metabolic risk score (boys =-5.339 vs. girls =-6.362). Conclusions: The results suggest that central obesity plays a mediating role in the relationship between somatic maturation and metabolic risk during adolescence. |
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Repositório Institucional da UNESP |
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spelling |
Biological Maturation, Central Adiposity, and Metabolic Risk in Adolescents: A Mediation AnalysisBackground: Earlier biological maturation has been related to increased metabolic risk. In this study, we verified mediating effects by central adiposity of the relationship between somatic maturity and metabolic risk factors in adolescents. Methods: In a cross-sectional study, 1034 adolescents aged 10-16 years from Londrina/PR/Brazil were evaluated. The age of peak height velocity (PHV) method was used to evaluate somatic maturity. Central adiposity was estimated through waist circumference measurements. Fasting glucose, triglycerides, high-density lipoprotein cholesterol (HDL-C), and blood pressure were measured as metabolic risk indicators. Physical activity (Baecke questionnaire) and cardiorespiratory fitness (20-m shuttle run test) were used as covariates. Results: Except for fasting glucose, waist circumference showed partial or full mediation of the relationship between maturity and the following metabolic risk factors with their respective z-score values: triglycerides (boys =-3.554 vs. girls =-5.031), HDL-C (boys = +5.300 vs. girls = +5.905), systolic blood pressure (boys =-3.540 vs. girls =-3.763), diastolic blood pressure (boys =-2.967 vs. girls =-3.264), and metabolic risk score (boys =-5.339 vs. girls =-6.362). Conclusions: The results suggest that central obesity plays a mediating role in the relationship between somatic maturation and metabolic risk during adolescence.Study and Research Group in Metabolism Nutrition and Exercise (GEPEMENE) Londrina State University, Rodovia Celso Garcia Cid, km 380Bradford Institute for Health Research Bradford NHS Foundation TrustLaboratory of Investigation in Exercise (LIVE) Department of Physical Education São Paulo State University (UNESP)Department of Pathology Clinical and Toxicological Analysis Center of Health Sciences Londrina State UniversityLaboratory of Investigation in Exercise (LIVE) Department of Physical Education São Paulo State University (UNESP)Universidade Estadual de Londrina (UEL)Bradford NHS Foundation TrustUniversidade Estadual Paulista (Unesp)Werneck, André O.Silva, Danilo R.Collings, Paul J.Fernandes, Rômulo A. [UNESP]Ronque, Enio R.V.Barbosa, Décio S.Cyrino, Edilson S.2018-12-11T16:43:55Z2018-12-11T16:43:55Z2016-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article377-383http://dx.doi.org/10.1089/chi.2016.0042Childhood Obesity, v. 12, n. 5, p. 377-383, 2016.2153-21762153-2168http://hdl.handle.net/11449/16898910.1089/chi.2016.00422-s2.0-84989169875Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengChildhood Obesity1,5301,530info:eu-repo/semantics/openAccess2021-10-23T15:48:34Zoai:repositorio.unesp.br:11449/168989Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T15:48:34Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Biological Maturation, Central Adiposity, and Metabolic Risk in Adolescents: A Mediation Analysis |
title |
Biological Maturation, Central Adiposity, and Metabolic Risk in Adolescents: A Mediation Analysis |
spellingShingle |
Biological Maturation, Central Adiposity, and Metabolic Risk in Adolescents: A Mediation Analysis Werneck, André O. |
title_short |
Biological Maturation, Central Adiposity, and Metabolic Risk in Adolescents: A Mediation Analysis |
title_full |
Biological Maturation, Central Adiposity, and Metabolic Risk in Adolescents: A Mediation Analysis |
title_fullStr |
Biological Maturation, Central Adiposity, and Metabolic Risk in Adolescents: A Mediation Analysis |
title_full_unstemmed |
Biological Maturation, Central Adiposity, and Metabolic Risk in Adolescents: A Mediation Analysis |
title_sort |
Biological Maturation, Central Adiposity, and Metabolic Risk in Adolescents: A Mediation Analysis |
author |
Werneck, André O. |
author_facet |
Werneck, André O. Silva, Danilo R. Collings, Paul J. Fernandes, Rômulo A. [UNESP] Ronque, Enio R.V. Barbosa, Décio S. Cyrino, Edilson S. |
author_role |
author |
author2 |
Silva, Danilo R. Collings, Paul J. Fernandes, Rômulo A. [UNESP] Ronque, Enio R.V. Barbosa, Décio S. Cyrino, Edilson S. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual de Londrina (UEL) Bradford NHS Foundation Trust Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Werneck, André O. Silva, Danilo R. Collings, Paul J. Fernandes, Rômulo A. [UNESP] Ronque, Enio R.V. Barbosa, Décio S. Cyrino, Edilson S. |
description |
Background: Earlier biological maturation has been related to increased metabolic risk. In this study, we verified mediating effects by central adiposity of the relationship between somatic maturity and metabolic risk factors in adolescents. Methods: In a cross-sectional study, 1034 adolescents aged 10-16 years from Londrina/PR/Brazil were evaluated. The age of peak height velocity (PHV) method was used to evaluate somatic maturity. Central adiposity was estimated through waist circumference measurements. Fasting glucose, triglycerides, high-density lipoprotein cholesterol (HDL-C), and blood pressure were measured as metabolic risk indicators. Physical activity (Baecke questionnaire) and cardiorespiratory fitness (20-m shuttle run test) were used as covariates. Results: Except for fasting glucose, waist circumference showed partial or full mediation of the relationship between maturity and the following metabolic risk factors with their respective z-score values: triglycerides (boys =-3.554 vs. girls =-5.031), HDL-C (boys = +5.300 vs. girls = +5.905), systolic blood pressure (boys =-3.540 vs. girls =-3.763), diastolic blood pressure (boys =-2.967 vs. girls =-3.264), and metabolic risk score (boys =-5.339 vs. girls =-6.362). Conclusions: The results suggest that central obesity plays a mediating role in the relationship between somatic maturation and metabolic risk during adolescence. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-10-01 2018-12-11T16:43:55Z 2018-12-11T16:43:55Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1089/chi.2016.0042 Childhood Obesity, v. 12, n. 5, p. 377-383, 2016. 2153-2176 2153-2168 http://hdl.handle.net/11449/168989 10.1089/chi.2016.0042 2-s2.0-84989169875 |
url |
http://dx.doi.org/10.1089/chi.2016.0042 http://hdl.handle.net/11449/168989 |
identifier_str_mv |
Childhood Obesity, v. 12, n. 5, p. 377-383, 2016. 2153-2176 2153-2168 10.1089/chi.2016.0042 2-s2.0-84989169875 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Childhood Obesity 1,530 1,530 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
377-383 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965274127990784 |