Second Brazilian consensus on the management of ulcerative colitis in adults: a consensus of the Brazilian Organization for Crohn’s Disease and Colitis (GEDIIB)

• Autor(a) principal: Baima, Júlio Pinheiro [UNESP]
• Data de Publicação: 2022
• Outros Autores: Imbrizi, Marcello, Andrade, Adriana Ribas, Chebli, Liliane Andrade, Argollo, Marjorie Costa, Queiroz, Natália Sousa Freitas, De Azevedo, Matheus Freitas Cardoso [UNESP], Vieira, Andrea, Costa, Marcia Henriques De Magalhães, Fróes, Renata de Sá Brito, Cancela E Penna, Francisco Guilherme, Quaresma, Abel Botelho, Damião, Aderson Omar Mourão Cintra [UNESP], Da Silva Moraes, Antonio Carlos, dos Santos, Carlos Henrique Marques, Flores, Cristina, Zaltman, Cyrla, Vilela, Eduardo Garcia, Morsoletto, Eloá, Gonçalves Filho, Francisco De Assis, Santana, Genoile Oliveira, Zabot, Gilmara Pandolfo, Parente, José Miguel Luz, Sassaki, Ligia Yukie [UNESP], Zerôncio, Marco Antonio, Machado, Marta Brenner, Cassol, Ornella Sari, Kotze, Paulo Gustavo, Parra, Rogerio Serafim, Miszputen, Sender Jankiel, Coy, Cláudio Saddy Rodrigues, Junior, Orlando Ambrogini, Chebli, Júlio Maria Fonseca, Saad-Hossne, Rogério [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1590/S0004-2803.2022005S1-03; http://hdl.handle.net/11449/248633
• topic: adults; Colitis, ulcerative; disease management; drug therapy; inflammatory bowel diseases

Background – Inflammatory bowel diseases are immune-mediated disorders that include Crohn’s disease (CD) and ulcerative colitis (UC). UC is a progressive disease that affects the colorectal mucosa causing debilitating symptoms leading to high morbidity and work disability. As a consequence of chronic colonic inflammation, UC is also associated with an increased risk of colorectal cancer. Objective – This consensus aims to provide guidance on the most effective medical management of adult patients with UC. Methods – A consensus statement was developed by stakeholders representing Brazilian gastroenterologists and colorectal surgeons (Brazilian Organization for Crohn’s Disease and Colitis [GEDIIB]). A systematic review including the most recent evidence was conducted to support the recommendations and statements. All recommendations/statements were endorsed using a modified Delphi Panel by the stakeholders/experts in inflammatory bowel disease with at least 80% or greater consensus. Results and conclusion – The medical recommendations (pharmacological and non-pharmacological) were mapped according to the stage of treatment and severity of the disease onto three domains: management and treatment (drug and surgical interventions), criteria for evaluating the effectiveness of medical treatment, and follow-up/ patient monitoring after initial treatment. The consensus targeted general practitioners, gastroenterologists and surgeons who manage patients with UC, and supports decision-making processes by health insurance companies, regulatory agencies, health institutional leaders, and administrators.