Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1155/2014/498961 http://hdl.handle.net/11449/117232 |
Resumo: | The aim of this study was to evaluate the effects of moderate aerobic exercise training on sleep, depression, cortisol, and markers of immune function in patients with chronic primary insomnia. Twenty-one sedentary participants (16 women aged 44.7 +/- 9 years) with chronic primary insomnia completed a 4-month intervention of moderate aerobic exercise. Compared with baseline, polysomnographic data showed improvements following exercise training. Also observed were reductions in depression symptoms and plasma cortisol. Immunologic assays revealed a significant increase in plasma apolipoprotein A (140.9 +/- 22 to 151.2 +/- 22mg/dL) and decreases in CD4 (915.6 +/- 361 to 789.6 +/- 310 mm(3)) and CD8 (532.4 +/- 259 to 435.7 +/- 204 mm(3)). Decreases in cortisol were significantly correlated with increases in total sleep time (r. = -0.51) and REMsleep (r. = -0.52). In summary, long-termmoderate aerobic exercise training improved sleep, reduced depression and cortisol, and promoted significant changes in immunologic variables. |
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Repositório Institucional da UNESP |
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Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomniaThe aim of this study was to evaluate the effects of moderate aerobic exercise training on sleep, depression, cortisol, and markers of immune function in patients with chronic primary insomnia. Twenty-one sedentary participants (16 women aged 44.7 +/- 9 years) with chronic primary insomnia completed a 4-month intervention of moderate aerobic exercise. Compared with baseline, polysomnographic data showed improvements following exercise training. Also observed were reductions in depression symptoms and plasma cortisol. Immunologic assays revealed a significant increase in plasma apolipoprotein A (140.9 +/- 22 to 151.2 +/- 22mg/dL) and decreases in CD4 (915.6 +/- 361 to 789.6 +/- 310 mm(3)) and CD8 (532.4 +/- 259 to 435.7 +/- 204 mm(3)). Decreases in cortisol were significantly correlated with increases in total sleep time (r. = -0.51) and REMsleep (r. = -0.52). In summary, long-termmoderate aerobic exercise training improved sleep, reduced depression and cortisol, and promoted significant changes in immunologic variables.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Associacao Fundo de Incentivo a Pesquisa (AFIP)Centro de Estudos em Psicobiologia e Exercicio (CEPE)Univ Fed Goias, Jatai, Go, BrazilUniv Fed Sao Paulo, Sao Paulo, BrazilUniv Estadual Paulista, Presidente Prudente, SP, BrazilArizona State Univ, Coll Nursing & Hlth Innovat & Exercise & Wellness, Phoenix, AZ USAPhoenix VA Hlth Care Syst, Phoenix, AZ USAUniv Fed Minas Gerais, Belo Horizonte, MG, BrazilUniv Estadual Paulista, Presidente Prudente, SP, BrazilFAPESP: 98/14303-3FAPESP: 08/02862-1Hindawi Publishing CorporationUniversidade Federal de Goiás (UFG)Universidade Federal de São Paulo (UNIFESP)Universidade Estadual Paulista (Unesp)Arizona State UnivPhoenix VA Hlth Care SystUniversidade Federal de Minas Gerais (UFMG)Passos, Giselle SoaresPoyares, DalvaSantana, Marcos GoncalvesSouza Teixeira, Alexandre Abilio deLira, Fabio Santos [UNESP]Youngstedt, Shawn D.Thomatieli dos Santos, Ronaldo VagnerTufik, SergioMello, Marco Tulio de2015-03-18T15:55:35Z2015-03-18T15:55:35Z2014-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/epub+zipapplication/pdfhttp://dx.doi.org/10.1155/2014/498961Biomed Research International. New York: Hindawi Publishing Corporation, 7 p., 2014.2314-6133http://hdl.handle.net/11449/11723210.1155/2014/498961WOS:000346709900001WOS000346709900001.pdfWOS000346709900001.epubWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBiomed Research International2.5830,935info:eu-repo/semantics/openAccess2024-06-18T17:42:46Zoai:repositorio.unesp.br:11449/117232Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T17:00:12.403668Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia |
title |
Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia |
spellingShingle |
Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia Passos, Giselle Soares |
title_short |
Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia |
title_full |
Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia |
title_fullStr |
Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia |
title_full_unstemmed |
Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia |
title_sort |
Exercise improves immune function, antidepressive response, and sleep quality in patients with chronic primary insomnia |
author |
Passos, Giselle Soares |
author_facet |
Passos, Giselle Soares Poyares, Dalva Santana, Marcos Goncalves Souza Teixeira, Alexandre Abilio de Lira, Fabio Santos [UNESP] Youngstedt, Shawn D. Thomatieli dos Santos, Ronaldo Vagner Tufik, Sergio Mello, Marco Tulio de |
author_role |
author |
author2 |
Poyares, Dalva Santana, Marcos Goncalves Souza Teixeira, Alexandre Abilio de Lira, Fabio Santos [UNESP] Youngstedt, Shawn D. Thomatieli dos Santos, Ronaldo Vagner Tufik, Sergio Mello, Marco Tulio de |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de Goiás (UFG) Universidade Federal de São Paulo (UNIFESP) Universidade Estadual Paulista (Unesp) Arizona State Univ Phoenix VA Hlth Care Syst Universidade Federal de Minas Gerais (UFMG) |
dc.contributor.author.fl_str_mv |
Passos, Giselle Soares Poyares, Dalva Santana, Marcos Goncalves Souza Teixeira, Alexandre Abilio de Lira, Fabio Santos [UNESP] Youngstedt, Shawn D. Thomatieli dos Santos, Ronaldo Vagner Tufik, Sergio Mello, Marco Tulio de |
description |
The aim of this study was to evaluate the effects of moderate aerobic exercise training on sleep, depression, cortisol, and markers of immune function in patients with chronic primary insomnia. Twenty-one sedentary participants (16 women aged 44.7 +/- 9 years) with chronic primary insomnia completed a 4-month intervention of moderate aerobic exercise. Compared with baseline, polysomnographic data showed improvements following exercise training. Also observed were reductions in depression symptoms and plasma cortisol. Immunologic assays revealed a significant increase in plasma apolipoprotein A (140.9 +/- 22 to 151.2 +/- 22mg/dL) and decreases in CD4 (915.6 +/- 361 to 789.6 +/- 310 mm(3)) and CD8 (532.4 +/- 259 to 435.7 +/- 204 mm(3)). Decreases in cortisol were significantly correlated with increases in total sleep time (r. = -0.51) and REMsleep (r. = -0.52). In summary, long-termmoderate aerobic exercise training improved sleep, reduced depression and cortisol, and promoted significant changes in immunologic variables. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-01-01 2015-03-18T15:55:35Z 2015-03-18T15:55:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1155/2014/498961 Biomed Research International. New York: Hindawi Publishing Corporation, 7 p., 2014. 2314-6133 http://hdl.handle.net/11449/117232 10.1155/2014/498961 WOS:000346709900001 WOS000346709900001.pdf WOS000346709900001.epub |
url |
http://dx.doi.org/10.1155/2014/498961 http://hdl.handle.net/11449/117232 |
identifier_str_mv |
Biomed Research International. New York: Hindawi Publishing Corporation, 7 p., 2014. 2314-6133 10.1155/2014/498961 WOS:000346709900001 WOS000346709900001.pdf WOS000346709900001.epub |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Biomed Research International 2.583 0,935 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
7 application/epub+zip application/pdf |
dc.publisher.none.fl_str_mv |
Hindawi Publishing Corporation |
publisher.none.fl_str_mv |
Hindawi Publishing Corporation |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1808128735678824448 |