Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probe

Detalhes bibliográficos
Autor(a) principal: Trevizan, Heitor Furlan [UNESP]
Data de Publicação: 2021
Outros Autores: Olean-Oliveira, André [UNESP], Cardoso, Celso Xavier [UNESP], Teixeira, Marcos F.S. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.snb.2021.130141
http://hdl.handle.net/11449/208712
Resumo: In the present study, we report the use of an electrochemical sensor for uric acid using a molecularly imprinted polymer (MIP) as a molecular recognition platform. The MIP was based on an azopolymer electropolymerized in the presence of uric acid used as a template molecule. The azo group of the polymer contributes to the quantifiable redox capacitance of the electrode surface, which can be probed by impedance/capacitance spectroscopy. Thus, the advantage of the developed sensor is its ability to perform direct measurements without a soluble redox probe. The molecularly imprinted polymer can sensitively transduce the recognition and binding of specific analytes by redox capacitance. Through electrochemical impedance spectroscopy (EIS) and electrochemical capacitive spectroscopy (ECS), unusual approaches were able to obtain different analytical curves with distinct characteristics, reaching a limit of detection of 0.160 μmol L−1.
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spelling Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probeAzopolymerMolecular recognitionMolecularly imprinted polymerResistive/capacitive sensorUric acidWithout redox probeIn the present study, we report the use of an electrochemical sensor for uric acid using a molecularly imprinted polymer (MIP) as a molecular recognition platform. The MIP was based on an azopolymer electropolymerized in the presence of uric acid used as a template molecule. The azo group of the polymer contributes to the quantifiable redox capacitance of the electrode surface, which can be probed by impedance/capacitance spectroscopy. Thus, the advantage of the developed sensor is its ability to perform direct measurements without a soluble redox probe. The molecularly imprinted polymer can sensitively transduce the recognition and binding of specific analytes by redox capacitance. Through electrochemical impedance spectroscopy (EIS) and electrochemical capacitive spectroscopy (ECS), unusual approaches were able to obtain different analytical curves with distinct characteristics, reaching a limit of detection of 0.160 μmol L−1.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Department of Chemistry and Biochemistry School of Science and Technology – Sao Paulo State University (UNESP), Rua Roberto Simonsen 305Department of Chemistry and Biochemistry School of Science and Technology – Sao Paulo State University (UNESP), Rua Roberto Simonsen 305FAPESP: 2016/09017-1CNPq: 301298/2017-3CAPES: 88882.434480/2019-01Universidade Estadual Paulista (Unesp)Trevizan, Heitor Furlan [UNESP]Olean-Oliveira, André [UNESP]Cardoso, Celso Xavier [UNESP]Teixeira, Marcos F.S. [UNESP]2021-06-25T11:17:47Z2021-06-25T11:17:47Z2021-09-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.snb.2021.130141Sensors and Actuators, B: Chemical, v. 343.0925-4005http://hdl.handle.net/11449/20871210.1016/j.snb.2021.1301412-s2.0-85106476696Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengSensors and Actuators, B: Chemicalinfo:eu-repo/semantics/openAccess2021-10-23T19:02:26Zoai:repositorio.unesp.br:11449/208712Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T19:02:26Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probe
title Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probe
spellingShingle Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probe
Trevizan, Heitor Furlan [UNESP]
Azopolymer
Molecular recognition
Molecularly imprinted polymer
Resistive/capacitive sensor
Uric acid
Without redox probe
title_short Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probe
title_full Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probe
title_fullStr Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probe
title_full_unstemmed Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probe
title_sort Development of a molecularly imprinted polymer for uric acid sensing based on a conductive azopolymer: Unusual approaches using electrochemical impedance/capacitance spectroscopy without a soluble redox probe
author Trevizan, Heitor Furlan [UNESP]
author_facet Trevizan, Heitor Furlan [UNESP]
Olean-Oliveira, André [UNESP]
Cardoso, Celso Xavier [UNESP]
Teixeira, Marcos F.S. [UNESP]
author_role author
author2 Olean-Oliveira, André [UNESP]
Cardoso, Celso Xavier [UNESP]
Teixeira, Marcos F.S. [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Trevizan, Heitor Furlan [UNESP]
Olean-Oliveira, André [UNESP]
Cardoso, Celso Xavier [UNESP]
Teixeira, Marcos F.S. [UNESP]
dc.subject.por.fl_str_mv Azopolymer
Molecular recognition
Molecularly imprinted polymer
Resistive/capacitive sensor
Uric acid
Without redox probe
topic Azopolymer
Molecular recognition
Molecularly imprinted polymer
Resistive/capacitive sensor
Uric acid
Without redox probe
description In the present study, we report the use of an electrochemical sensor for uric acid using a molecularly imprinted polymer (MIP) as a molecular recognition platform. The MIP was based on an azopolymer electropolymerized in the presence of uric acid used as a template molecule. The azo group of the polymer contributes to the quantifiable redox capacitance of the electrode surface, which can be probed by impedance/capacitance spectroscopy. Thus, the advantage of the developed sensor is its ability to perform direct measurements without a soluble redox probe. The molecularly imprinted polymer can sensitively transduce the recognition and binding of specific analytes by redox capacitance. Through electrochemical impedance spectroscopy (EIS) and electrochemical capacitive spectroscopy (ECS), unusual approaches were able to obtain different analytical curves with distinct characteristics, reaching a limit of detection of 0.160 μmol L−1.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-25T11:17:47Z
2021-06-25T11:17:47Z
2021-09-15
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.snb.2021.130141
Sensors and Actuators, B: Chemical, v. 343.
0925-4005
http://hdl.handle.net/11449/208712
10.1016/j.snb.2021.130141
2-s2.0-85106476696
url http://dx.doi.org/10.1016/j.snb.2021.130141
http://hdl.handle.net/11449/208712
identifier_str_mv Sensors and Actuators, B: Chemical, v. 343.
0925-4005
10.1016/j.snb.2021.130141
2-s2.0-85106476696
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Sensors and Actuators, B: Chemical
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799965717461729280

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