Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.bej.2022.108658 http://hdl.handle.net/11449/246024 |
Resumo: | Microbial astaxanthin are preferred over the synthetic equivalent, not only to impart color in a wide variety of products but also to provide bioactive antioxidants nutrients to human health. The yeast Phaffia rhodozyma is considered as one of the most important natural sources of astaxanthin. The present research work was designed to enhance the biosynthesis of astaxanthin by using synthetic substrates and moving from orbital shaker to 4 L stirred tank bioreactor (STB). Moreover, it was also evaluated the potential of astaxanthin-rich extracts in dyeing textile fabrics. Under optimal conditions in STB [carbon source (glucose/xylose) and aeration rate (1 vvm) with constant light irradiation], the process production achieved a 503.66 μg/gDCW (+ 48.99%) of astaxanthin compared to the orbital shakers (256.88 μg/gDCW). The in vitro antioxidant activity and potential cytotoxicity assessment of astaxanthin-rich extracts was evaluated, indicating the potential of astaxanthin to be used as a natural dyeing agent for textiles, envisioning the replacement of synthetic colorants by natural counterpart. |
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Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeingAntioxidantCarotenoidsSubmerged cultureTextile matrixYeastMicrobial astaxanthin are preferred over the synthetic equivalent, not only to impart color in a wide variety of products but also to provide bioactive antioxidants nutrients to human health. The yeast Phaffia rhodozyma is considered as one of the most important natural sources of astaxanthin. The present research work was designed to enhance the biosynthesis of astaxanthin by using synthetic substrates and moving from orbital shaker to 4 L stirred tank bioreactor (STB). Moreover, it was also evaluated the potential of astaxanthin-rich extracts in dyeing textile fabrics. Under optimal conditions in STB [carbon source (glucose/xylose) and aeration rate (1 vvm) with constant light irradiation], the process production achieved a 503.66 μg/gDCW (+ 48.99%) of astaxanthin compared to the orbital shakers (256.88 μg/gDCW). The in vitro antioxidant activity and potential cytotoxicity assessment of astaxanthin-rich extracts was evaluated, indicating the potential of astaxanthin to be used as a natural dyeing agent for textiles, envisioning the replacement of synthetic colorants by natural counterpart.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Escuela de Agronomía Facultad de Ciencias Agronómicas y de los Alimentos Pontificia Universidad Católica de ValparaísoLaboratory of Biotechnology School of Chemistry and Food Federal University of Rio Grande, RSSão Paulo State University (UNESP) School of Pharmaceutical Sciences Department of Bioprocess Engineering and Biotechnology, São PauloBioprocess Engineering Laboratory School of Chemistry and Food Federal University of Rio Grande, RSDepartment of Pharmaceutical-Biochemical Technology School of Pharmaceutical Sciences University of São Paulo, São PauloSão Paulo State University (UNESP) School of Pharmaceutical Sciences Department of Bioprocess Engineering and Biotechnology, São PauloFAPESP: 2019/15493–9FAPESP: 2020/08655–0FAPESP: 2021/06686–8CNPq: 312463/2021–9Pontificia Universidad Católica de ValparaísoFederal University of Rio GrandeUniversidade Estadual Paulista (UNESP)Universidade de São Paulo (USP)Mussagy, Cassamo U.Silva, Pedro G.P.Amantino, Camila F. [UNESP]Burkert, Janaina F.M.Primo, Fernando L. [UNESP]Pessoa, AdalbertoSantos-Ebinuma, Valeria C. [UNESP]2023-07-29T12:29:43Z2023-07-29T12:29:43Z2022-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.bej.2022.108658Biochemical Engineering Journal, v. 187.1873-295X1369-703Xhttp://hdl.handle.net/11449/24602410.1016/j.bej.2022.1086582-s2.0-85139352068Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBiochemical Engineering Journalinfo:eu-repo/semantics/openAccess2023-07-29T12:29:44Zoai:repositorio.unesp.br:11449/246024Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:15:46.765816Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing |
title |
Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing |
spellingShingle |
Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing Mussagy, Cassamo U. Antioxidant Carotenoids Submerged culture Textile matrix Yeast |
title_short |
Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing |
title_full |
Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing |
title_fullStr |
Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing |
title_full_unstemmed |
Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing |
title_sort |
Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing |
author |
Mussagy, Cassamo U. |
author_facet |
Mussagy, Cassamo U. Silva, Pedro G.P. Amantino, Camila F. [UNESP] Burkert, Janaina F.M. Primo, Fernando L. [UNESP] Pessoa, Adalberto Santos-Ebinuma, Valeria C. [UNESP] |
author_role |
author |
author2 |
Silva, Pedro G.P. Amantino, Camila F. [UNESP] Burkert, Janaina F.M. Primo, Fernando L. [UNESP] Pessoa, Adalberto Santos-Ebinuma, Valeria C. [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Pontificia Universidad Católica de Valparaíso Federal University of Rio Grande Universidade Estadual Paulista (UNESP) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Mussagy, Cassamo U. Silva, Pedro G.P. Amantino, Camila F. [UNESP] Burkert, Janaina F.M. Primo, Fernando L. [UNESP] Pessoa, Adalberto Santos-Ebinuma, Valeria C. [UNESP] |
dc.subject.por.fl_str_mv |
Antioxidant Carotenoids Submerged culture Textile matrix Yeast |
topic |
Antioxidant Carotenoids Submerged culture Textile matrix Yeast |
description |
Microbial astaxanthin are preferred over the synthetic equivalent, not only to impart color in a wide variety of products but also to provide bioactive antioxidants nutrients to human health. The yeast Phaffia rhodozyma is considered as one of the most important natural sources of astaxanthin. The present research work was designed to enhance the biosynthesis of astaxanthin by using synthetic substrates and moving from orbital shaker to 4 L stirred tank bioreactor (STB). Moreover, it was also evaluated the potential of astaxanthin-rich extracts in dyeing textile fabrics. Under optimal conditions in STB [carbon source (glucose/xylose) and aeration rate (1 vvm) with constant light irradiation], the process production achieved a 503.66 μg/gDCW (+ 48.99%) of astaxanthin compared to the orbital shakers (256.88 μg/gDCW). The in vitro antioxidant activity and potential cytotoxicity assessment of astaxanthin-rich extracts was evaluated, indicating the potential of astaxanthin to be used as a natural dyeing agent for textiles, envisioning the replacement of synthetic colorants by natural counterpart. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-11-01 2023-07-29T12:29:43Z 2023-07-29T12:29:43Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.bej.2022.108658 Biochemical Engineering Journal, v. 187. 1873-295X 1369-703X http://hdl.handle.net/11449/246024 10.1016/j.bej.2022.108658 2-s2.0-85139352068 |
url |
http://dx.doi.org/10.1016/j.bej.2022.108658 http://hdl.handle.net/11449/246024 |
identifier_str_mv |
Biochemical Engineering Journal, v. 187. 1873-295X 1369-703X 10.1016/j.bej.2022.108658 2-s2.0-85139352068 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Biochemical Engineering Journal |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129180799336448 |