Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing

Detalhes bibliográficos
Autor(a) principal: Mussagy, Cassamo U.
Data de Publicação: 2022
Outros Autores: Silva, Pedro G.P., Amantino, Camila F. [UNESP], Burkert, Janaina F.M., Primo, Fernando L. [UNESP], Pessoa, Adalberto, Santos-Ebinuma, Valeria C. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.bej.2022.108658
http://hdl.handle.net/11449/246024
Resumo: Microbial astaxanthin are preferred over the synthetic equivalent, not only to impart color in a wide variety of products but also to provide bioactive antioxidants nutrients to human health. The yeast Phaffia rhodozyma is considered as one of the most important natural sources of astaxanthin. The present research work was designed to enhance the biosynthesis of astaxanthin by using synthetic substrates and moving from orbital shaker to 4 L stirred tank bioreactor (STB). Moreover, it was also evaluated the potential of astaxanthin-rich extracts in dyeing textile fabrics. Under optimal conditions in STB [carbon source (glucose/xylose) and aeration rate (1 vvm) with constant light irradiation], the process production achieved a 503.66 μg/gDCW (+ 48.99%) of astaxanthin compared to the orbital shakers (256.88 μg/gDCW). The in vitro antioxidant activity and potential cytotoxicity assessment of astaxanthin-rich extracts was evaluated, indicating the potential of astaxanthin to be used as a natural dyeing agent for textiles, envisioning the replacement of synthetic colorants by natural counterpart.
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spelling Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeingAntioxidantCarotenoidsSubmerged cultureTextile matrixYeastMicrobial astaxanthin are preferred over the synthetic equivalent, not only to impart color in a wide variety of products but also to provide bioactive antioxidants nutrients to human health. The yeast Phaffia rhodozyma is considered as one of the most important natural sources of astaxanthin. The present research work was designed to enhance the biosynthesis of astaxanthin by using synthetic substrates and moving from orbital shaker to 4 L stirred tank bioreactor (STB). Moreover, it was also evaluated the potential of astaxanthin-rich extracts in dyeing textile fabrics. Under optimal conditions in STB [carbon source (glucose/xylose) and aeration rate (1 vvm) with constant light irradiation], the process production achieved a 503.66 μg/gDCW (+ 48.99%) of astaxanthin compared to the orbital shakers (256.88 μg/gDCW). The in vitro antioxidant activity and potential cytotoxicity assessment of astaxanthin-rich extracts was evaluated, indicating the potential of astaxanthin to be used as a natural dyeing agent for textiles, envisioning the replacement of synthetic colorants by natural counterpart.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Escuela de Agronomía Facultad de Ciencias Agronómicas y de los Alimentos Pontificia Universidad Católica de ValparaísoLaboratory of Biotechnology School of Chemistry and Food Federal University of Rio Grande, RSSão Paulo State University (UNESP) School of Pharmaceutical Sciences Department of Bioprocess Engineering and Biotechnology, São PauloBioprocess Engineering Laboratory School of Chemistry and Food Federal University of Rio Grande, RSDepartment of Pharmaceutical-Biochemical Technology School of Pharmaceutical Sciences University of São Paulo, São PauloSão Paulo State University (UNESP) School of Pharmaceutical Sciences Department of Bioprocess Engineering and Biotechnology, São PauloFAPESP: 2019/15493–9FAPESP: 2020/08655–0FAPESP: 2021/06686–8CNPq: 312463/2021–9Pontificia Universidad Católica de ValparaísoFederal University of Rio GrandeUniversidade Estadual Paulista (UNESP)Universidade de São Paulo (USP)Mussagy, Cassamo U.Silva, Pedro G.P.Amantino, Camila F. [UNESP]Burkert, Janaina F.M.Primo, Fernando L. [UNESP]Pessoa, AdalbertoSantos-Ebinuma, Valeria C. [UNESP]2023-07-29T12:29:43Z2023-07-29T12:29:43Z2022-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.bej.2022.108658Biochemical Engineering Journal, v. 187.1873-295X1369-703Xhttp://hdl.handle.net/11449/24602410.1016/j.bej.2022.1086582-s2.0-85139352068Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBiochemical Engineering Journalinfo:eu-repo/semantics/openAccess2023-07-29T12:29:44Zoai:repositorio.unesp.br:11449/246024Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:15:46.765816Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing
title Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing
spellingShingle Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing
Mussagy, Cassamo U.
Antioxidant
Carotenoids
Submerged culture
Textile matrix
Yeast
title_short Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing
title_full Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing
title_fullStr Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing
title_full_unstemmed Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing
title_sort Production of natural astaxanthin by Phaffia rhodozyma and its potential application in textile dyeing
author Mussagy, Cassamo U.
author_facet Mussagy, Cassamo U.
Silva, Pedro G.P.
Amantino, Camila F. [UNESP]
Burkert, Janaina F.M.
Primo, Fernando L. [UNESP]
Pessoa, Adalberto
Santos-Ebinuma, Valeria C. [UNESP]
author_role author
author2 Silva, Pedro G.P.
Amantino, Camila F. [UNESP]
Burkert, Janaina F.M.
Primo, Fernando L. [UNESP]
Pessoa, Adalberto
Santos-Ebinuma, Valeria C. [UNESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Pontificia Universidad Católica de Valparaíso
Federal University of Rio Grande
Universidade Estadual Paulista (UNESP)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Mussagy, Cassamo U.
Silva, Pedro G.P.
Amantino, Camila F. [UNESP]
Burkert, Janaina F.M.
Primo, Fernando L. [UNESP]
Pessoa, Adalberto
Santos-Ebinuma, Valeria C. [UNESP]
dc.subject.por.fl_str_mv Antioxidant
Carotenoids
Submerged culture
Textile matrix
Yeast
topic Antioxidant
Carotenoids
Submerged culture
Textile matrix
Yeast
description Microbial astaxanthin are preferred over the synthetic equivalent, not only to impart color in a wide variety of products but also to provide bioactive antioxidants nutrients to human health. The yeast Phaffia rhodozyma is considered as one of the most important natural sources of astaxanthin. The present research work was designed to enhance the biosynthesis of astaxanthin by using synthetic substrates and moving from orbital shaker to 4 L stirred tank bioreactor (STB). Moreover, it was also evaluated the potential of astaxanthin-rich extracts in dyeing textile fabrics. Under optimal conditions in STB [carbon source (glucose/xylose) and aeration rate (1 vvm) with constant light irradiation], the process production achieved a 503.66 μg/gDCW (+ 48.99%) of astaxanthin compared to the orbital shakers (256.88 μg/gDCW). The in vitro antioxidant activity and potential cytotoxicity assessment of astaxanthin-rich extracts was evaluated, indicating the potential of astaxanthin to be used as a natural dyeing agent for textiles, envisioning the replacement of synthetic colorants by natural counterpart.
publishDate 2022
dc.date.none.fl_str_mv 2022-11-01
2023-07-29T12:29:43Z
2023-07-29T12:29:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.bej.2022.108658
Biochemical Engineering Journal, v. 187.
1873-295X
1369-703X
http://hdl.handle.net/11449/246024
10.1016/j.bej.2022.108658
2-s2.0-85139352068
url http://dx.doi.org/10.1016/j.bej.2022.108658
http://hdl.handle.net/11449/246024
identifier_str_mv Biochemical Engineering Journal, v. 187.
1873-295X
1369-703X
10.1016/j.bej.2022.108658
2-s2.0-85139352068
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Biochemical Engineering Journal
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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