The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo de conferência |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNESP |
| Texto Completo: | http://dx.doi.org/10.1117/12.2283317 http://hdl.handle.net/11449/170565 |
Resumo: | We have been searching for new photosensitizers (PS) for photodynamic therapy (PDT) of cancer based on extracts from Amazonian plants since 2009. In this paper, we demonstrate that, under certain conditions, the extract from fruits of the Amazonian palm Euterpe oleraceae (popular name Açaí) can serve as a PS for PDT treatment of murine breast cancer cells (4T1 cell line). We have been first to show directly that the photodynamic effect of plant PS is due to singlet oxygen. |
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The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cellsamazon Palm Treecancer cellslaserMTT methodnanoemulsionPDTplant extractPSsinglet oxygenUV-Vis and fluorescent spectraWe have been searching for new photosensitizers (PS) for photodynamic therapy (PDT) of cancer based on extracts from Amazonian plants since 2009. In this paper, we demonstrate that, under certain conditions, the extract from fruits of the Amazonian palm Euterpe oleraceae (popular name Açaí) can serve as a PS for PDT treatment of murine breast cancer cells (4T1 cell line). We have been first to show directly that the photodynamic effect of plant PS is due to singlet oxygen.Immanuel Kant Baltic Federal University Interdisciplinary Reference Centre, 14 A.Nevskogo St.Universidade Federal Do Acre Biotecnologia e BiodiversidadeSão Paulo State University (UNESP) Institute of BiosciencesHerminio Ometto University Center (FHO UNIARARAS)Paulista University (UNIP)São Paulo State University (UNESP) Institute of BiosciencesInterdisciplinary Reference CentreBiotecnologia e BiodiversidadeUniversidade Estadual Paulista (Unesp)Herminio Ometto University Center (FHO UNIARARAS)Paulista University (UNIP)Tcibulnikova, Anna V.Degterev, Igor A.Bryukhanov, Valery V.Roberto, Mantuanelly M. [UNESP]Campos Pereira, F. D. [UNESP]Marin-Morales, M. A. [UNESP]Slezhkin, Vasily A.Samusev, Ilya G.2018-12-11T16:51:20Z2018-12-11T16:51:20Z2017-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectapplication/pdfhttp://dx.doi.org/10.1117/12.2283317Proceedings of SPIE - The International Society for Optical Engineering, v. 10456.1996-756X0277-786Xhttp://hdl.handle.net/11449/17056510.1117/12.22833172-s2.0-850407209662-s2.0-85040720966.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengProceedings of SPIE - The International Society for Optical Engineeringinfo:eu-repo/semantics/openAccess2023-10-05T06:08:05Zoai:repositorio.unesp.br:11449/170565Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-05-23T11:35:03.309160Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
| dc.title.none.fl_str_mv |
The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells |
| title |
The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells |
| spellingShingle |
The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells Tcibulnikova, Anna V. amazon Palm Tree cancer cells laser MTT method nanoemulsion PDT plant extract PS singlet oxygen UV-Vis and fluorescent spectra |
| title_short |
The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells |
| title_full |
The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells |
| title_fullStr |
The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells |
| title_full_unstemmed |
The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells |
| title_sort |
The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells |
| author |
Tcibulnikova, Anna V. |
| author_facet |
Tcibulnikova, Anna V. Degterev, Igor A. Bryukhanov, Valery V. Roberto, Mantuanelly M. [UNESP] Campos Pereira, F. D. [UNESP] Marin-Morales, M. A. [UNESP] Slezhkin, Vasily A. Samusev, Ilya G. |
| author_role |
author |
| author2 |
Degterev, Igor A. Bryukhanov, Valery V. Roberto, Mantuanelly M. [UNESP] Campos Pereira, F. D. [UNESP] Marin-Morales, M. A. [UNESP] Slezhkin, Vasily A. Samusev, Ilya G. |
| author2_role |
author author author author author author author |
| dc.contributor.none.fl_str_mv |
Interdisciplinary Reference Centre Biotecnologia e Biodiversidade Universidade Estadual Paulista (Unesp) Herminio Ometto University Center (FHO UNIARARAS) Paulista University (UNIP) |
| dc.contributor.author.fl_str_mv |
Tcibulnikova, Anna V. Degterev, Igor A. Bryukhanov, Valery V. Roberto, Mantuanelly M. [UNESP] Campos Pereira, F. D. [UNESP] Marin-Morales, M. A. [UNESP] Slezhkin, Vasily A. Samusev, Ilya G. |
| dc.subject.por.fl_str_mv |
amazon Palm Tree cancer cells laser MTT method nanoemulsion PDT plant extract PS singlet oxygen UV-Vis and fluorescent spectra |
| topic |
amazon Palm Tree cancer cells laser MTT method nanoemulsion PDT plant extract PS singlet oxygen UV-Vis and fluorescent spectra |
| description |
We have been searching for new photosensitizers (PS) for photodynamic therapy (PDT) of cancer based on extracts from Amazonian plants since 2009. In this paper, we demonstrate that, under certain conditions, the extract from fruits of the Amazonian palm Euterpe oleraceae (popular name Açaí) can serve as a PS for PDT treatment of murine breast cancer cells (4T1 cell line). We have been first to show directly that the photodynamic effect of plant PS is due to singlet oxygen. |
| publishDate |
2017 |
| dc.date.none.fl_str_mv |
2017-01-01 2018-12-11T16:51:20Z 2018-12-11T16:51:20Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
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conferenceObject |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1117/12.2283317 Proceedings of SPIE - The International Society for Optical Engineering, v. 10456. 1996-756X 0277-786X http://hdl.handle.net/11449/170565 10.1117/12.2283317 2-s2.0-85040720966 2-s2.0-85040720966.pdf |
| url |
http://dx.doi.org/10.1117/12.2283317 http://hdl.handle.net/11449/170565 |
| identifier_str_mv |
Proceedings of SPIE - The International Society for Optical Engineering, v. 10456. 1996-756X 0277-786X 10.1117/12.2283317 2-s2.0-85040720966 2-s2.0-85040720966.pdf |
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eng |
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eng |
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Proceedings of SPIE - The International Society for Optical Engineering |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
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Universidade Estadual Paulista (UNESP) |
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UNESP |
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UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
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