Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopy

Detalhes bibliográficos
Autor(a) principal: Coelho, K. I.R.
Data de Publicação: 1981
Outros Autores: Bryden, A. S., Hall, Cheryl, Flewett, T. H.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3109/01913128109031504
http://hdl.handle.net/11449/230803
Resumo: Pathologic changes induced in the small intestine of suckling mice by rotavirus infection were studied by conventional histology, immunofluorescence, scanning electron microscopy, and electron microscopy of ultrathin sections. Infection could be detected within 24 hours in a few mice, but after 2 days it was well established. Swollen, often vacuolated infected cells were found on the sides and tips of villi from which they rapidly became detached; microvilli showed variable irregularity. Immature enterocytes from crypts replaced lost infected cells. By the tenth day very few infected cells could still be found. Both tubular structures and spherical particles occurred in the infected cells. Only tubular structures were found in nuclei. © 1981 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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spelling Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopyGastroenteritisIleumMouseRotavirusScanningPathologic changes induced in the small intestine of suckling mice by rotavirus infection were studied by conventional histology, immunofluorescence, scanning electron microscopy, and electron microscopy of ultrathin sections. Infection could be detected within 24 hours in a few mice, but after 2 days it was well established. Swollen, often vacuolated infected cells were found on the sides and tips of villi from which they rapidly became detached; microvilli showed variable irregularity. Immature enterocytes from crypts replaced lost infected cells. By the tenth day very few infected cells could still be found. Both tubular structures and spherical particles occurred in the infected cells. Only tubular structures were found in nuclei. © 1981 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.Departamento de Patologia Faculdade de Medicina, 18600, Botucatu Sao PauloFaculdade de MedicinaCoelho, K. I.R.Bryden, A. S.Hall, CherylFlewett, T. H.2022-04-29T08:42:13Z2022-04-29T08:42:13Z1981-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article59-80http://dx.doi.org/10.3109/01913128109031504Ultrastructural Pathology, v. 2, n. 1, p. 59-80, 1981.0191-3123http://hdl.handle.net/11449/23080310.3109/019131281090315042-s2.0-0019466155Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengUltrastructural Pathologyinfo:eu-repo/semantics/openAccess2022-04-29T08:42:13Zoai:repositorio.unesp.br:11449/230803Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-29T08:42:13Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopy
title Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopy
spellingShingle Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopy
Coelho, K. I.R.
Gastroenteritis
Ileum
Mouse
Rotavirus
Scanning
title_short Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopy
title_full Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopy
title_fullStr Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopy
title_full_unstemmed Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopy
title_sort Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopy
author Coelho, K. I.R.
author_facet Coelho, K. I.R.
Bryden, A. S.
Hall, Cheryl
Flewett, T. H.
author_role author
author2 Bryden, A. S.
Hall, Cheryl
Flewett, T. H.
author2_role author
author
author
dc.contributor.none.fl_str_mv Faculdade de Medicina
dc.contributor.author.fl_str_mv Coelho, K. I.R.
Bryden, A. S.
Hall, Cheryl
Flewett, T. H.
dc.subject.por.fl_str_mv Gastroenteritis
Ileum
Mouse
Rotavirus
Scanning
topic Gastroenteritis
Ileum
Mouse
Rotavirus
Scanning
description Pathologic changes induced in the small intestine of suckling mice by rotavirus infection were studied by conventional histology, immunofluorescence, scanning electron microscopy, and electron microscopy of ultrathin sections. Infection could be detected within 24 hours in a few mice, but after 2 days it was well established. Swollen, often vacuolated infected cells were found on the sides and tips of villi from which they rapidly became detached; microvilli showed variable irregularity. Immature enterocytes from crypts replaced lost infected cells. By the tenth day very few infected cells could still be found. Both tubular structures and spherical particles occurred in the infected cells. Only tubular structures were found in nuclei. © 1981 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
publishDate 1981
dc.date.none.fl_str_mv 1981-01-01
2022-04-29T08:42:13Z
2022-04-29T08:42:13Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3109/01913128109031504
Ultrastructural Pathology, v. 2, n. 1, p. 59-80, 1981.
0191-3123
http://hdl.handle.net/11449/230803
10.3109/01913128109031504
2-s2.0-0019466155
url http://dx.doi.org/10.3109/01913128109031504
http://hdl.handle.net/11449/230803
identifier_str_mv Ultrastructural Pathology, v. 2, n. 1, p. 59-80, 1981.
0191-3123
10.3109/01913128109031504
2-s2.0-0019466155
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ultrastructural Pathology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 59-80
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799965337344540672

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